2026 February-2 - 76 articles
The Wuding chicken, a renowned indigenous breed in Yunnan Province, is prized for its superior meat quality; however, its economic potential is limited by pronounced broodiness and suboptimal egg production. Central to alleviating these constraints i...
Understanding the spatiotemporal dynamics of medicinal plant distributions and their quality responses under climate change is essential for formulating forward-looking conservation and utilization strategies. In response to the increasing depletion...
Root rot disease severely impacts the yield of Cardamine violifolia, a selenium-enriched cruciferous vegetable. However, the causal pathogens and effective control strategies of this disease remain poorly characterized. This study systematically isol...
Cystic fibrosis (CF) is a multisystem genetic disorder in which malnutrition has historically been a major determinant of disease severity. The advent of CFTR modulators has significantly altered the nutritional and functional profile of CF patients....
Yam end black disease (YEBD) is a devastating soil-borne disease that severely compromises the yield of Chinese yam (Dioscorea opposita Thunb.). Despite its agricultural importance, the etiological agents and molecular mechanisms underlying YEBD rema...
Sea cucumber viscera, the primary by-product of processing, are generated in increasing quantities annually, leading to significant environmental pollution and resource wastage. Nevertheless, they are rich in nutrients and possess diverse bioactiviti...
Bone metastases represent a major cause of morbidity in advanced cancers, yet the neural regulation of metastatic growth within bone remains largely unexplored. The skeletal system is richly innervated by sensory and sympathetic nerve fibers that inf...
Bivalves possess a diverse array of photoreceptive organs that are significant for their evolutionary success and systematic classification. Giant clams are the largest bivalve mollusks, with mantle tissue permanently extended in nature to maintain s...
Background: The interaction between keratinocytes and proinflammatory cytokines is essential in the development of psoriatic lesions. The synergism among these cytokines and their involvement in ferroptosis are not yet elucidated. This study aimed at...
In applying a hierarchical mixed model to genome-wide association analysis (GWAS) of longitudinal data, dimensionality reduction through modeling repeated measurements improves both computational efficiency and statistical power. Legendre polynomials...
Olfaction plays a central role in mammalian social behavior, yet its contribution to group coordination remains poorly understood. Here, we show that olfactory impairment in adult C57BL/6J mice (Mus musculus) leads to the spontaneous emergence of str...
Understanding the ecological drivers of plant-associated microbiota is essential for predicting grassland ecosystem resilience. This study aimed to characterize the community structure, functional potential, and soil environmental drivers of rhizosph...
Landscape features often shape maternal genetic structure by influencing connectivity. In this study, habitat fragmentation, a major threat to the Asian elephant (Elephas maximus), was assessed through an integrated approach involving mitochondrial D...
Influenza’s pandemic threat is driven by antigenic drift, which limits the efficacy of conventional vaccines. To address this challenge, we established a clinical serum-anchored computational design pipeline for a broad-spectrum multi-epitope m...
Small-cell lung cancer (SCLC) is the most lethal histologic subtype of lung cancer. It is characterized by rapid tumor growth and early metastatic dissemination, resulting in an extremely poor prognosis. The addition of immunotherapy to standard chem...
Retinol-binding protein 4 (RBP4), an adipokine secreted by adipose tissues, has been implicated in metabolic inflammation and insulin resistance. Type 2 diabetes (T2D) is a recognized risk factor for osteoarthritis, with both conditions characterized...
Salt stress is a major environmental constraint affecting plant growth and productivity. Crop wild relatives provide valuable genetic resources for stress tolerance, yet transcriptomic information for forest-derived wild species remains limited. In t...
This study provides the first insights into the biology of the blue crab Callinectes sapidus in the Loukkos Estuary, based on 461 individuals collected between December 2022 and November 2023. Results indicate a well-structured invasive population. C...
Sympatric species share identical geographical spaces, climatic conditions and survival pressures. Comparative chloroplast genomes among Anna and Lysionotus sympatric species enable exploration of genome-wide evolutionary dynamics of sympatric specie...
Global climate problems and the sharp decline in biodiversity have attracted widespread attention. Orchids, as the “flagship” species of biodiversity, are important indicators of ecological changes. This study took Chongqing as the study...
This study aimed to explore genetic variants associated with serum albumin (ALB) levels in Chinese winter sports athletes using genome-wide association analysis (GWAS) and to investigate potential regulatory mechanisms using bioinformatics annotation...
Purple rice contains beneficial bioactive compounds, but the concentrations can be influenced by the growing conditions. This study investigated the interactive effects of water regime, biochar amendment, and nitrogen (N) sources on the yield and gra...
The proper regulation of signaling pathways, including WNT signaling, during early embryonic development is critical for whole-organism development. In particular, maternally enriched WNTs play critical roles in cell cleavage and axis formation throu...
Exposure to T2 toxin is known to induce hepatotoxicity and gut dysbiosis, yet effective dietary interventions remain underexplored. This study investigates the hepatoprotective and microbiota-modulating effects of lycopene against T2 toxin-induced to...
Ophiocordyceps sinensis, a fungus parasitic on insects, attracts interest due to its unique medicinal applications and complex ecological interactions. The potential relationship between codon usage bias and the parasitic relationship between O. sine...
Alzheimer’s disease (AD) is the most common neurodegenerative disorder worldwide, for which aging represents the main risk factor. As the global elderly population expands, the prevalence of Alzheimer’s disease escalates rapidly. Notably,...
Potato common scab is a widespread soil-borne disease that severely reduces tuber quality and market value. However, the diversity of common scab pathogens and the availability of resistance resources in major potato-producing regions of China remain...
C2H2-type zinc finger transcription factors play crucial roles in regulating plant growth and responses to abiotic stresses. Although pear is an economically important fruit crop with available genomic resources, the comprehensive analyses of its C2H...
Ventricular arrhythmias are among the most life-threatening cardiac rhythm disturbances. Owing to their complex pathophysiology and high mortality risk, they remain a major focus of research aimed at elucidating underlying mechanisms and improving pr...
Heavy metal pollution in aquatic environments presents a considerable risk to fish populations, primarily through the induction of oxidative damage. This study aimed to investigate the relationship between heavy metals (Cu, Cd, Hg, and Pb) and As acc...
Extrachromosomal circular DNA (eccDNA) has emerged as a pivotal contributor to cancer progression, facilitating oncogene amplification, dysregulated gene expression, and tumor heterogeneity. Despite its significance in cancer, the interplay between e...
Ophiocordyceps sinensis (O. sinensis) is a valuable medicinal fungus distributed in the Qinghai–Tibet Plateau and adjacent high-altitude regions. Wild excavation has raised increasing concerns about its impact on fragile alpine soil ecosystems....
Marine fish communities in the Yangtze River Estuary and Adjacent East China Sea (YRE-ECS) are subject to complex environmental gradients; however, their multidimensional assembly mechanisms remain insufficiently resolved. Here, we integrated environ...
Environmental DNA (eDNA) metabarcoding has become a powerful, non-invasive method for detecting aquatic organisms. However, optimal sampling strategies for benthic taxa in lentic ecosystems remain unclear. This study evaluated the effectiveness of eD...
High-altitude grazing animals are continuously exposed to strong wind and low temperature, which challenge physiological homeostasis and energy metabolism. Improving living conditions and nutritional supplementation are two commonly used strategies....
Mycobacterium bovis is the causative agent of tuberculosis (TB) infecting a wide range of animal hosts, including humans. Domestic pigs (Sus scrofa domestica) are susceptible to different mycobacteria, particularly species within the Mycobacterium av...
Leigh Syndrome Spectrum (LSS) is a rare and heterogeneous disease continuum with most published cohorts in small sizes that limit the statistical power. Large-scale meta-analyses with published case-level clinical data extracted from the literature a...
Macrophage polarization is widely recognized as a pivotal role in the maintenance of liver homeostasis. Lysolecithin (LPC) has previously been associated with hepatoprotective effect. This study aimed to determine whether LPC protected against lipopo...
Trollius chinensis Bunge (TCB), a perennial Ranunculaceae herb, produces Flos Trollii-dried flowers with medicinal properties including heat clearing, detoxification, and relieving oral/throat discomfort, eye pain, and cold-induced fever. TCB is main...
River channel development and hydraulic engineering alter natural flow-velocity patterns, subjecting Triplophysa orientalis to heightened hydrodynamic stress and energy expenditure in high-flow-velocity habitats. Regulating the molecular regulatory m...
The half-life of proteins is determined by the “information” carried within specific regions of the protein. Lysine methylation is an emerging post-translational modification that can act at the decision node. In contrast to the charge-ne...
Biological invasion is a major driver of biodiversity loss and ecosystem disruption, with non-native aquatic species threatening ecological integrity and economic stability. The Qinling Mountains, located in central China, serve as a crucial barrier...
This study aimed to elucidate the dynamic changes in meat quality attributes and metabolomic profiles of Dezhou donkey longissimus lumborum (LL) during extended chilled storage. Donkey longissimus lumborum (LL) muscles (n = 4) were vacuum-packaged 24...
Riverine ecosystems represent critical nodes in the global carbon cycle, where the mechanistic role of viruses in modulating eukaryotic carbon cycling remains underexplored, particularly across heterogeneous landscapes. Here, we applied metatranscrip...
Penicillium expansum inflicts significant economic damage in the fruit and vegetable industry due to its wide distribution and ability to infect a diverse range of hosts. Therefore, developing safe and environmentally sustainable strategies to suppre...
Microbial spoilage and foodborne pathogens remain central challenges in food safety, driven by the metabolic resilience and ecological adaptability of bacteria, yeasts, and molds across diverse food matrices. Active antimicrobial packaging has emerge...
Aquatic organisms are continuously challenged by dynamic environmental factors, including temperature, salinity fluctuations, and dissolved oxygen levels [...]
Although the diterpenoid alkaloids of Aconitum carmichaelii Debx. have long been a research focus in phytochemistry and pharmacology, systematic studies on the growth and development of its daughter roots remain limited, yet this process critically d...
With the continuous development of the livestock industry, the availability of high-quality roughage is becoming increasingly constrained. Therefore, the exploitation of unconventional feed resources is crucial for the sustainable development of the...
(1) Background. Parabuthus liosoma is one of the largest buthid scorpion species and is endemic to Saudi Arabia and Yemen. This study provides the first DNA barcoding and phylogenetic analysis of P. liosoma from Saudi Arabia, contributing to global e...
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