Table of Contents
Pathogens, Volume 9, Issue 10 (October 2020) – 85 articles
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Cover Story (view full-size image) The fungus Candida albicans and the Gram-positive bacterium Staphylococcus aureus are among the [...] Read more. The fungus Candida albicans and the Gram-positive bacterium Staphylococcus aureus are among the most frequent etiological agents of opportunistic nosocomial infections and are often co-isolated forming mixed biofilms. These fungal/bacterial biofilms are particularly difficult to control and eradicate by virtue of their high levels of resistance against conventional antibiotics. Previous studies reported on the potent activity of silver nanoparticles (AgNPs) against single species biofilms formed by either C. albicans or S. aureus, including MRSA. In this article, we demonstrate that these AgNPs are active in vitro against mixed C. albicans/MRSA dual-species biofilms. Furthermore, we demonstrate that functionalization of catheter material with AgNPs inhibits the formation of these mixed fungal/bacterial biofilms. Vew this paper.