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Current Oncology, Volume 30, Issue 4

April 2023 - 62 articles

Cover Story: Although surgery represents the most potentially curative therapeutic option for patients with resectable non-small cell lung cancer (NSCLC), their five-year survival remains poor, ranging from 67% for those with T1N0 (IA) disease to 23% for those with T1-3N2 (IIIA). Immune checkpoint inhibitors have recently been found to be treatment options in the neoadjuvant and adjuvant settings, thus significantly improving patients’ prognosis. Like what has happened in the metastatic setting, their development has been shifted from immune checkpoint inhibitor monotherapy to concurrent chemo-immunotherapy. In the current review, we explore the results from clinical trials that have determined the introduction of immunotherapy in patients with early-stage NSCLC. View this paper
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Articles (62)

  • Review
  • Open Access
15 Citations
7,299 Views
14 Pages

20 April 2023

The treatment paradigm for metastatic castrate-sensitive prostate cancer (mCSPC) has evolved rapidly in the past decade with the approval of several life-prolonging therapies including docetaxel chemotherapy and multiple androgen receptor pathway inh...

  • Systematic Review
  • Open Access
9 Citations
4,573 Views
14 Pages

A Systematic Review Assessing the Impact of Vitamin D Levels on Adult Patients with Lymphoid Malignancies

  • Cristina Potre,
  • Ema Borsi,
  • Ovidiu Potre,
  • Ioana Ionita,
  • Miruna Samfireag,
  • Dan Costachescu,
  • Cristina Secosan,
  • Sandra Lazar and
  • Anca Irina Ristescu

20 April 2023

Vitamin D deficiency has been correlated with various conditions, including the risk of developing lymphoid malignancies. This systematic review aimed to assess the association between vitamin D levels at diagnosis of lymphoid malignancies, patient o...

  • Review
  • Open Access
11 Citations
14,299 Views
22 Pages

20 April 2023

Antibody-Drug conjugates (ADCs) are a relatively new class of drugs with a promise to improve the outcomes in specific cancers. By delivering the cytotoxic agent to tumor cells expressing specific antigens, ADCs achieve a better therapeutic index and...

  • Article
  • Open Access
6 Citations
3,486 Views
18 Pages

20 April 2023

Primary central nervous system (CNS) tumours are heterogeneous, with different treatment pathways and prognoses depending on their histological and molecular classification. Due to their anatomical location, all CNS tumours, regardless of malignancy,...

  • Review
  • Open Access
22 Citations
5,059 Views
10 Pages

Single-Port Robot-Assisted Radical Prostatectomy: Where Do We Stand?

  • Antonio Franco,
  • Antony A. Pellegrino,
  • Cosimo De Nunzio,
  • Morgan Salkowski,
  • Jamal C. Jackson,
  • Lucas B. Zukowski,
  • Enrico Checcucci,
  • Srinivas Vourganti,
  • Alexander K. Chow and
  • Francesco Porpiglia
  • + 3 authors

20 April 2023

In 2018, the da Vinci Single Port (SP) robotic system was approved by the US Food and Drug Administration for urologic procedures. Available studies for the application of SP to prostate cancer surgery are limited. The aim of our study is to summariz...

  • Article
  • Open Access
7 Citations
3,810 Views
12 Pages

Clinicopathological Characteristics, Treatment Patterns, and Outcomes in Patients with Laryngeal Cancer

  • Dejan Đokanović,
  • Radoslav Gajanin,
  • Zdenka Gojković,
  • Goran Marošević,
  • Igor Sladojević,
  • Vesna Gajanin,
  • Olja Jović-Đokanović and
  • Ljiljana Amidžić

20 April 2023

Background: Various factors can affect the survival of patients with laryngeal cancer (LC). In this retrospective study, we assessed clinicopathological features, their prognostic value, and treatment modalities for patients with confirmed squamous c...

  • Article
  • Open Access
3 Citations
2,369 Views
14 Pages

The Effect of Contemporary Brachytherapy Practices on Prognosis in Women with Locally Advanced Cervical Cancer

  • Janna J. Laan,
  • Luc R. C. W. van Lonkhuijzen,
  • Jaap A. Stokking,
  • Danique L. J. Barten,
  • Karel A. Hinnen,
  • Bradley R. Pieters,
  • Lukas J. A. Stalpers and
  • Henrike Westerveld

19 April 2023

(1) Background: Over the past two decades use of new imaging modalities and the adaptation of applicators have allowed for advances in volumetric (3D) imaging-based brachytherapy practices for patients with locally advanced cervical cancer. The aim o...

  • Comment
  • Open Access
7 Citations
2,383 Views
6 Pages

19 April 2023

We read with great interest the manuscript by Brassetti et al. recently published in your journal and hope it will encourage discussion and debate around the optimization of the surgical management of patients with penile cancer (PECa) [...]

  • Article
  • Open Access
7 Citations
2,591 Views
12 Pages

Clinical Rationale of Using Steerable Technologies for Radiofrequency Ablation Followed by Cavity Creation and Cement Augmentation in the Treatment of Painful Spinal Metastases

  • Claudio Pusceddu,
  • Salvatore Marsico,
  • Daniele Derudas,
  • Nicola Ballicu,
  • Luca Melis,
  • Stefano Zedda,
  • Carlo De Felice,
  • Alessandro Calabrese,
  • Domiziana Santucci and
  • Eliodoro Faiella

19 April 2023

(1) Background: Cement distribution after radiofrequency ablation of spinal metastases can be unpredictable due to various tumor factors, and vertebral augmentation requires advanced devices to prevent cement leakage and achieve satisfactory filling....

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Curr. Oncol. - ISSN 1718-7729