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Current Oncology, Volume 29, Issue 3

March 2022 - 66 articles

Cover Story: Craniopharyngiomas (CPs) are slow-growing benign intracranial tumors located in the sellar–suprasellar region. Although they are non-malignant, their location and relationship to adjacent neural and vascular structures complicates a complete resection and results in complications. CPs are divided into the adamantinomatous (ACPs) and the papillary (PCPs) subtypes. The main pathways involved in CPs development and recurrence include the wingless (Wnt)/β-catenin and the mitogen-activated protein kinases/extracellular signal-regulated kinase (MAPK/ERK). The current treatment of CPs includes surgery followed by radiation. The latest advances in surgical techniques, imaging tools, and instrumentations have led to the evolution of surgery using endoscopic procedures, with residual components being treated by recent radiotherapy, chemotherapy, and novel immunotherapies. View this paper
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Articles (66)

  • Article
  • Open Access
11 Citations
3,924 Views
9 Pages

Cutaneous Melanoma in Alpine Population: Incidence Trends and Clinicopathological Profile

  • Alessandra Buja,
  • Massimo Rugge,
  • Giuseppe De Luca,
  • Emanuela Bovo,
  • Manuel Zorzi,
  • Chiara De Toni,
  • Claudia Cozzolino,
  • Antonella Vecchiato,
  • Paolo Del Fiore and
  • Romina Spina
  • + 4 authors

21 March 2022

Previous studies associated high-level exposure to ultraviolet radiation with a greater risk of cutaneous malignant melanoma (CMM). This study focuses on the changing incidence of CMM over time (from 1990 to 2017) in the Veneto region of Northeast It...

  • Article
  • Open Access
24 Citations
10,967 Views
11 Pages

Genomic Landscape of Non-Small Cell Lung Cancer (NSCLC) in East Asia Using Circulating Tumor DNA (ctDNA) in Clinical Practice

  • Byoung Chul Cho,
  • Herbert H. F. Loong,
  • Chun-Ming Tsai,
  • Man Lung P. Teo,
  • Hye Ryun Kim,
  • Sun Min Lim,
  • Suyog Jain,
  • Steve Olsen and
  • Keunchil Park

21 March 2022

Plasma-based next-generation sequencing (NGS) has demonstrated the potential to guide the personalized treatment of non-small cell lung cancer (NSCLC). Inherent differences in mutational genomic profiles of NSCLC exist between Asian and Western popul...

  • Article
  • Open Access
32 Citations
4,982 Views
13 Pages

Prevalence and Persistence of Anxiety and Depression over Five Years since Breast Cancer Diagnosis—The NEON-BC Prospective Study

  • Catarina Lopes,
  • Luisa Lopes-Conceição,
  • Filipa Fontes,
  • Augusto Ferreira,
  • Susana Pereira,
  • Nuno Lunet and
  • Natália Araújo

21 March 2022

Anxiety and depression are frequent among patients with breast cancer (BCa). Evidence of the persistence and recovery from these conditions and their determinants is scarce. We describe the occurrence of clinically significant anxiety and depression...

  • Communication
  • Open Access
5 Citations
4,494 Views
9 Pages

Risk-Reducing Options for High-Grade Serous Gynecologic Malignancy in BRCA1/2

  • Lauren Clarfield,
  • Laura Diamond and
  • Michelle Jacobson

21 March 2022

Ovarian cancer (OC) is the leading cause of death among women with gynecologic malignancy. Breast Cancer Susceptibility Gene 1 (BRCA 1) and Breast Cancer Susceptibility Gene 2 (BRCA 2) germline mutations confer an estimated 20 to 40 times increased r...

  • Article
  • Open Access
5 Citations
4,389 Views
13 Pages

19 March 2022

For women with genetic risk of breast cancer, the addition of screening breast MRI to mammography has become a standard. The order and interval of annual imaging can be variable among providers. To evaluate the clinical implications related to the ti...

  • Article
  • Open Access
3 Citations
3,266 Views
13 Pages

19 March 2022

Our objective was to examine the prevalence of mental health symptoms and the behavioral impact of the COVID-19 pandemic on cancer survivors who endorse cannabis. Participants included 158 adults (≥18 years) who self-reported medicinal cannabis us...

  • Article
  • Open Access
6 Citations
4,681 Views
15 Pages

18 March 2022

The incidence of BM among Canadian cancer patients is unknown. We aimed to estimate IP of BM at the time of cancer diagnosis and during the lifetime of patients with selected primary cancers. Data on BM at diagnosis from 2010–2017 was obtained...

  • Perspective
  • Open Access
1 Citations
3,591 Views
10 Pages

Perspective on Cancer Control: Whither the Tobacco Endgame for Canada?

  • Elizabeth A. Eisenhauer,
  • Robert Schwartz,
  • Rob Cunningham,
  • Les Hagen,
  • Geoffrey T. Fong,
  • Cynthia Callard,
  • Michael Chaiton and
  • Andrew Pipe

18 March 2022

Aims: In 2014, in response to evidence that Canada’s tobacco use would lead, inexorably, to substantial morbidity and mortality for the foreseeable future, a group of experts convened to consider the development of a “Tobacco Endgame&rdqu...

  • Communication
  • Open Access
1 Citations
2,737 Views
8 Pages

Evaluation of Patient-Reported Outcome Differences by Radiotherapy Techniques for Bone Metastases in A Population-Based Healthcare System

  • Robert A. Olson,
  • Vincent LaPointe,
  • Alex Benny,
  • Matthew Chan,
  • Shilo Lefresne and
  • Michael McKenzie

18 March 2022

We assessed whether advanced RT techniques were associated with differences in patient-reported outcomes (PROs). Patients with bone metastases who completed the brief pain inventory (BPI) before and after RT were identified, and RT technique was cate...

  • Viewpoint
  • Open Access
16 Citations
6,228 Views
9 Pages

17 March 2022

Canada lacks a national drug insurance plan. The home province or territory of a patient determines which cancer drugs are available on the public formulary, who is eligible for public coverage and what portion of the financial burden of cancer care...

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Curr. Oncol. - ISSN 1718-7729Creative Common CC BY license