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Marine Drugs, Volume 22, Issue 6

June 2024 - 54 articles

Cover Story: The discovery of new actinobacterial natural products goes beyond Streptomyces species, with rarer taxa's secondary metabolism offering a prolific route to uncover novel chemistry. The investigation of a macroalgae-associated Cellulosimicrobium strain, selected during biological screening, led to the discovery of cellulamides, a new family of marine-sourced linear peptides, the first natural products ever described from the genus Cellulosimicrobium. View this paper
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Articles (54)

  • Article
  • Open Access
3 Citations
2,589 Views
13 Pages

10 June 2024

A novel fibrinolytic enzyme, BSFE1, was isolated from the marine bacterium Bacillus sp. S-3685 (GenBank No.: KJ023685) found in the South China Sea. This enzyme, with a molecular weight of approximately 42 kDa and a specific activity of 736.4 U/mg, e...

  • Article
  • Open Access
4 Citations
2,139 Views
13 Pages

Halenaquinol Blocks Staphylococcal Protein A Anchoring on Cell Wall Surface by Inhibiting Sortase A in Staphylococcus aureus

  • Jaepil Lee,
  • Jae-Hyeong Choi,
  • Jayho Lee,
  • Eunji Cho,
  • Yeon-Ju Lee,
  • Hyi-Seung Lee and
  • Ki-Bong Oh

10 June 2024

Sortase A (SrtA) is a cysteine transpeptidase that binds to the periplasmic membrane and plays a crucial role in attaching surface proteins, including staphylococcal protein A (SpA), to the peptidoglycan cell wall. Six pentacyclic polyketides (1&ndas...

  • Article
  • Open Access
7 Citations
2,637 Views
15 Pages

Purification and Structural Analyses of Sulfated Polysaccharides from Low-Value Sea Cucumber Stichopus naso and Anticoagulant Activities of Its Oligosaccharides

  • Lige Cui,
  • Huifang Sun,
  • Xiaolei Shang,
  • Jing Wen,
  • Pengfei Li,
  • Shengtao Yang,
  • Linxia Chen,
  • Xiangyang Huang,
  • Haoyang Li and
  • Ronghua Yin
  • + 1 author

8 June 2024

Three polysaccharides (SnNG, SnFS and SnFG) were purified from the body wall of Stichopus naso. The physicochemical properties, including monosaccharide composition, molecular weight, sulfate content, and optical rotation, were analyzed, confirming t...

  • Article
  • Open Access
4 Citations
2,725 Views
22 Pages

Status of Fishery Discards and By-Products in Greece and Potential Valorization Scenarios towards a National Exploitation Master Plan

  • Efstratios Roussos,
  • George Triantaphyllidis,
  • Vassiliki Ilia,
  • Konstantinos Tsagarakis,
  • Athanasios Machias,
  • Leto-Aikaterini Tziveleka,
  • Vassilios Roussis,
  • Efstathia Ioannou and
  • Yannis Kotzamanis

7 June 2024

The valorization of aquaculture/fishery processing by-products, as well as unavoidable/unwanted catches and discards in Greece, is currently an underutilized activity despite the fact that there are several best practices in Northern Europe and overs...

  • Article
  • Open Access
1,923 Views
15 Pages

Elements in Serum, Muscle, Liver, and Kidney of Rabbits Fed Macroalgae-Supplemented Diets

  • Sabela Al-Soufi,
  • Marta Miranda,
  • Javier García,
  • Antonio Muíños,
  • Eugenio Cegarra,
  • Nuria Nicodemus,
  • Carlos Herrero-Latorre and
  • Marta López-Alonso

7 June 2024

The addition of marine macroalgae to animal feed has garnered interest due to the demonstrated benefits of gut health in many livestock species. Most macroalgae have a higher mineral content than terrestrial vegetables, making them an attractive, sus...

  • Communication
  • Open Access
1 Citations
1,855 Views
9 Pages

6 June 2024

Three new cyclic lipopeptides, olenamidonins A-C (1–3), in addition to two previously reported metabolites (4 and 5), were accumulated in the ΔdtxRso deletion mutant of deepsea-derived Streptomyces olivaceus SCSIO 1071. The structures of...

  • Article
  • Open Access
4 Citations
3,158 Views
11 Pages

5 June 2024

Utilization of fish rest raw material for fish oil extraction has received interest with the increasing demand for sustainable food sources. Enzymatic hydrolysis is an efficient method for the extraction of value-added compounds, but its effectivenes...

  • Article
  • Open Access
2 Citations
2,721 Views
19 Pages

5 June 2024

TRAF6 is an E3 ubiquitin ligase that plays a crucial role in cell signaling. It is known that MMP is involved in tumor metastasis, and TRAF6 induces MMP-9 expression by binding to BSG. However, inhibiting TRAF6’s ubiquitinase activity without d...

  • Article
  • Open Access
4 Citations
2,207 Views
11 Pages

Chrysomycins, Anti-Tuberculosis C-Glycoside Polyketides from Streptomyces sp. MS751

  • Jiaming Yu,
  • Hui Guo,
  • Jing Zhang,
  • Jiansen Hu,
  • Hongtao He,
  • Caixia Chen,
  • Na Yang,
  • Fan Yang,
  • Zexu Lin and
  • Huanqin Dai
  • + 6 authors

3 June 2024

A new dimeric C-glycoside polyketide chrysomycin F (1), along with four new monomeric compounds, chrysomycins G (2), H (3), I (4), J (5), as well as three known analogues, chrysomycins A (6), B (7), and C (8), were isolated and characterised from a s...

  • Article
  • Open Access
2,141 Views
15 Pages

Distribution and Level of Bioactive Monoacylglycerols in 12 Marine Microalgal Species

  • Giovanna Santaniello,
  • Gianna Falascina,
  • Marcello Ziaco,
  • Laura Fioretto,
  • Angela Sardo,
  • Martina Carelli,
  • Mariarosaria Conte,
  • Giovanna Romano and
  • Adele Cutignano

31 May 2024

Microalgae are currently considered an attractive source of highly valuable metabolites potentially exploitable as anticancer agents, nutraceuticals and cosmeceuticals and for bioenergy purposes. Their ease of culturing and their high growth rates fu...

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Mar. Drugs - ISSN 1660-3397