You are currently viewing a new version of our website. To view the old version click .

Marine Drugs, Volume 22, Issue 5

May 2024 - 44 articles

Cover Story: Thirty-two fungal polyketide derivatives, including eleven new compounds together with one new naturally occurring metabolite, were isolated and identified from the deep-sea cold-seep-derived fungus Talaromyces sp. CS-258. Among them, racemic ((±)-11) or epimeric (1315, 25, and 26) mixtures were successfully separated, and 27 represents a rarely reported iodinated compound. Their structures were determined by extensive analysis via NMR, MS, single-crystal X-ray diffraction, Mosher’s method, and ECD or NMR calculation (with DP4+ probability analysis). Possible biosynthetic routes of some isolated compounds were put forward. Eleven compounds showed broad-spectrum antibacterial activities against several human and aquatic pathogens. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (44)

  • Article
  • Open Access
6 Citations
2,645 Views
17 Pages

20 May 2024

The deep-sea bacterium Spongiibacter nanhainus CSC3.9 has significant inhibitory effects on agricultural pathogenic fungi and human pathogenic bacteria, especially Pseudomonas aeruginosa, the notorious multidrug-resistant pathogen affecting human pub...

  • Article
  • Open Access
1 Citations
2,492 Views
13 Pages

Marine-Derived Sulfated Glycans Inhibit the Interaction of Heparin with Adhesion Proteins of Mycoplasma pneumoniae

  • Jiyuan Yang,
  • Yuefan Song,
  • Ke Xia,
  • Vitor H. Pomin,
  • Chunyu Wang,
  • Mingqiang Qiao,
  • Robert J. Linhardt,
  • Jonathan S. Dordick and
  • Fuming Zhang

20 May 2024

Mycoplasma pneumoniae, a notable pathogen behind respiratory infections, employs specialized proteins to adhere to the respiratory epithelium, an essential process for initiating infection. The role of glycosaminoglycans, especially heparan sulfate,...

  • Article
  • Open Access
1 Citations
2,097 Views
12 Pages

Denigrins H–L: Sulfated Derivatives of Denigrins D and E from a New Zealand Dictyodendrilla c.f. dendyi Marine Sponge

  • Lauren Gris,
  • Michèle R. Prinsep,
  • Linda M. Peters and
  • Christopher N. Battershill

20 May 2024

Five new sulfated arylpyrrole and arylpyrrolone alkaloids, denigrins H–L (1–5), along with two known compounds, dictyodendrin B and denigrin G, were isolated from an extract of a New Zealand Dictyodendrilla c.f. dendyi marine sponge. Deni...

  • Article
  • Open Access
9 Citations
2,340 Views
16 Pages

High-Level Extracellular Production of a Trisaccharide-Producing Alginate Lyase AlyC7 in Escherichia coli and Its Agricultural Application

  • Xiao-Han Wang,
  • Yu-Qiang Zhang,
  • Xin-Ru Zhang,
  • Xiao-Dong Zhang,
  • Xiao-Meng Sun,
  • Xiao-Fei Wang,
  • Xiao-Hui Sun,
  • Xiao-Yan Song,
  • Yu-Zhong Zhang and
  • Ning Wang
  • + 2 authors

18 May 2024

Alginate oligosaccharides (AOS), products of alginate degradation by endotype alginate lyases, possess favorable biological activities and have broad applications. Although many have been reported, alginate lyases with homogeneous AOS products and se...

  • Review
  • Open Access
4 Citations
3,105 Views
15 Pages

17 May 2024

Heart disease is one of the leading causes of death worldwide, and it is estimated that 17.9 million people die of it each year. The risk factors for cardiovascular diseases are attributable to an unhealthy and sedentary lifestyle, poor nutrition, st...

  • Article
  • Open Access
6 Citations
2,265 Views
16 Pages

17 May 2024

Among female oncology patients, cervical cancer stands as the fourth most prevalent malignancy, exerting significant impacts on their health. Over 600,000 women received the diagnosis of cervical cancer in 2020, and the illness claimed over 300,000 l...

  • Article
  • Open Access
5 Citations
2,321 Views
25 Pages

Viral Infection Leads to a Unique Suite of Allelopathic Chemical Signals in Three Diatom Host–Virus Pairs

  • Bethanie R. Edwards,
  • Kimberlee Thamatrakoln,
  • Helen F. Fredricks,
  • Kay D. Bidle and
  • Benjamin A. S. Van Mooy

17 May 2024

Ecophysiological stress and the grazing of diatoms are known to elicit the production of chemical defense compounds called oxylipins, which are toxic to a wide range of marine organisms. Here we show that (1) the viral infection and lysis of diatoms...

  • Article
  • Open Access
11 Citations
3,542 Views
26 Pages

Phytochemical Composition, Anti-Inflammatory Property, and Anti-Atopic Effect of Chaetomorpha linum Extract

  • Luisa Frusciante,
  • Michela Geminiani,
  • Alfonso Trezza,
  • Tommaso Olmastroni,
  • Pierfrancesco Mastroeni,
  • Laura Salvini,
  • Stefania Lamponi,
  • Andrea Bernini,
  • Daniela Grasso and
  • Elena Dreassi
  • + 2 authors

17 May 2024

Utilizing plant-based resources, particularly their by-products, aligns with sustainability principles and circular bioeconomy, contributing to environmental preservation. The therapeutic potential of plant extracts is garnering increasing interest,...

  • Article
  • Open Access
10 Citations
3,098 Views
25 Pages

16 May 2024

In an attempt to reduce such decay induced by pathogenic causes, several studies investigated the effectiveness of nanoparticles (NPs) that play a vital role in saving food products, especially fruits. Current research delves into biogenic silver nan...

  • Article
  • Open Access
2 Citations
1,688 Views
13 Pages

Predigested Mixture of Arachidonic and Docosahexaenoic Acids for Better Bio-Accessibility

  • Assamae Chabni,
  • Blanca Pardo de Donlebún,
  • Marina Romero and
  • Carlos F. Torres

16 May 2024

A predigested product from arachidonic acid oil (ARA) and docosahexaenoic acid (DHA) oil in a 2:1 (w/w) ratio has been developed and evaluated in an in vitro digestion model. To produce this predigested lipid mixture, first, the two oils were enzymat...

of 5

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Mar. Drugs - ISSN 1660-3397Creative Common CC BY license