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Marine Drugs, Volume 22, Issue 6

June 2024 - 54 articles

Cover Story: The discovery of new actinobacterial natural products goes beyond Streptomyces species, with rarer taxa's secondary metabolism offering a prolific route to uncover novel chemistry. The investigation of a macroalgae-associated Cellulosimicrobium strain, selected during biological screening, led to the discovery of cellulamides, a new family of marine-sourced linear peptides, the first natural products ever described from the genus Cellulosimicrobium. View this paper
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Articles (54)

  • Article
  • Open Access
5 Citations
2,464 Views
16 Pages

20 June 2024

To promote the bioconversion of marine chitin waste into value-added products, we expressed a novel pH-stable Micromonospora aurantiaca-derived chitinase, MaChi1, in Escherichia coli and subsequently purified, characterized, and evaluated it for its...

  • Article
  • Open Access
2 Citations
2,412 Views
16 Pages

20 June 2024

Cadmium (Cd) is a toxic heavy metal that causes nephrosis, including acute kidney injury. To prevent and treat acute kidney injury (AKI) following Cd exposure, a tripeptide, Ser-Arg-Pro (SRP), from Sipunculus nudus L. was employed, and its potential...

  • Article
  • Open Access
2 Citations
5,898 Views
19 Pages

Reversed-Phase Medium-Pressure Liquid Chromatography Purification of Omega-3 Fatty Acid Ethyl Esters Using AQ-C18

  • Mingxin Sang,
  • Nan Pan,
  • Jingna Wu,
  • Xiaoting Chen,
  • Shuilin Cai,
  • Huan Fang,
  • Meitian Xiao,
  • Xiaoming Jiang and
  • Zhiyu Liu

19 June 2024

Omega-3 fatty acids are in high demand due to their efficacy in treating hypertriglyceridemia and preventing cardiovascular diseases. However, the growth of the industry is hampered by low purity and insufficient productivity. This study aims to deve...

  • Article
  • Open Access
9 Citations
5,394 Views
19 Pages

Optimizing the Extraction of Bioactive Compounds from Porphyra linearis (Rhodophyta): Evaluating Alkaline and Enzymatic Hydrolysis for Nutraceutical Applications

  • Débora Tomazi Pereira,
  • Paz García-García,
  • Nathalie Korbee,
  • Julia Vega,
  • Francisco J. Señoráns and
  • Félix L. Figueroa

18 June 2024

Porphyra sensu lato is one of the most economically significant and widely cultured and consumed algae in the world. Porphyra species present excellent nutraceutic properties due to their bioactive compounds (BACs). This research aimed to find the mo...

  • Article
  • Open Access
3 Citations
3,138 Views
16 Pages

Isaridin E Protects against Sepsis by Inhibiting Von Willebrand Factor-Induced Endothelial Hyperpermeability and Platelet–Endothelium Interaction

  • Yao-Sheng Liu,
  • Wen-Liang Chen,
  • Yu-Wei Zeng,
  • Zhi-Hong Li,
  • Hao-Lin Zheng,
  • Ni Pan,
  • Li-Yan Zhao,
  • Shu Wang,
  • Sen-Hua Chen and
  • Ming-Hua Jiang
  • + 7 authors

16 June 2024

Endothelial hyperpermeability is pivotal in sepsis-associated multi-organ dysfunction. Increased von Willebrand factor (vWF) plasma levels, stemming from activated platelets and endothelium injury during sepsis, can bind to integrin αvβ3,...

  • Article
  • Open Access
10 Citations
2,288 Views
10 Pages

New Cyclic Pentapeptides from the Mangrove-Derived Aspergillus fumigatus GXIMD 03099

  • Yu Wang,
  • Guangping Cao,
  • Yuman Gan,
  • Xiao Lin,
  • Xiangxi Yi,
  • Longyan Zhao,
  • Yonghong Liu,
  • Chenghai Gao and
  • Meng Bai

16 June 2024

Four new cyclic pentapeptides, avellanins D–G (1–4), together with four known compounds (5–8), were isolated from a mangrove-derived Aspergillus fumigatus GXIMD 03099 fungus from Acanthus ilicifolius L. Their structures were elucida...

  • Article
  • Open Access
6 Citations
2,867 Views
21 Pages

Innovative Alkanediol-Based Eutectic Solvents for Extracting/Pre-Formulating Dermatologically Valuable Free Fatty Acids from Spirulina and Porphyridium Cakes

  • Laura Wils,
  • Mervé Yagmur,
  • Nicolas Bellin,
  • Myriam Phelippe,
  • Alia Chevalley,
  • Charles Bodet and
  • Leslie Boudesocque-Delaye

15 June 2024

The growing demand for phycobiliproteins from microalgae generates a significant volume of by-products, such as extraction cakes. These cakes are enriched with products of interest for the cosmetics market, namely free fatty acids, particularly polyu...

  • Article
  • Open Access
12 Citations
5,551 Views
23 Pages

Improvement of Alginate Extraction from Brown Seaweed (Laminaria digitata L.) and Valorization of Its Remaining Ethanolic Fraction

  • Ivana M. Savić Gajić,
  • Ivan M. Savić,
  • Aleksandra M. Ivanovska,
  • Jovana D. Vunduk,
  • Ivana S. Mihalj and
  • Zorica B. Svirčev

15 June 2024

This study aimed to improve the conventional procedure of alginate isolation from the brown seaweed (Laminaria digitata L.) biomass and investigate the possibility of further valorization of the ethanolic fraction representing the byproduct after the...

  • Article
  • Open Access
2 Citations
1,908 Views
17 Pages

14 June 2024

Ichthyotoxic red tide is a problem that the world is facing and needs to solve. The use of antialgal compounds from marine macroalgae to suppress ichthyotoxic red tide is considered a promising biological control method. Antialgal substances were scr...

  • Article
  • Open Access
7 Citations
2,856 Views
18 Pages

14 June 2024

Overwhelming evidence points to an aberrant Wnt/β-catenin signaling as a critical factor in hepatocellular carcinoma (HCC) and cervical cancer (CC) pathogenesis. Dicerandrol C (DD-9), a dimeric tetrahydroxanthenone isolated from the endophytic f...

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Mar. Drugs - ISSN 1660-3397