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Marine Drugs, Volume 16, Issue 5

May 2018 - 38 articles

Cover Story: The purpose of this study is to change the paradigm based on the harvest/extraction approach and replace it with remote trapping of marine invertebrate molecules. This ecofriendly and sustainable approach aimed to exploit the animals in their natural habitat and to highlight the interdependence between the animal and its neighbors and between the animal and its symbionts. Our results demonstrate that when maintaining Crambe crambe and Anemonia sulcate in an aquarium and trapping the compounds released in the water, we succeeded in isolating and identifying toxic compounds to Anemonia, released by Crambe. Thus, This publication provide the proof of concept of a technology named Somartex® for (Self Operating MARine Trapping EXtractor) which was patented and built in order to transfer the concept from closed aquarium systems to open marine ecosystems. View this paper.
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Articles (38)

  • Article
  • Open Access
17 Citations
5,530 Views
12 Pages

Structure of the Exopolysaccharide Secreted by a Marine Strain Vibrio alginolyticus

  • Sophie Drouillard,
  • Isabelle Jeacomine,
  • Laurine Buon,
  • Claire Boisset,
  • Anthony Courtois,
  • Bertrand Thollas,
  • Pierre-Yves Morvan,
  • Romuald Vallée and
  • William Helbert

15 May 2018

Vibrio alginolyticus (CNCM I-4151) secretes an exopolysaccharide whose carbohydrate backbone is decorated with amino acids, likely conferring its properties that are appreciated in cosmetics. Here, the secreted polysaccharide of another strain of V....

  • Review
  • Open Access
249 Citations
19,757 Views
17 Pages

Marine Microalgae with Anti-Cancer Properties

  • Kevin A. Martínez Andrade,
  • Chiara Lauritano,
  • Giovanna Romano and
  • Adrianna Ianora

15 May 2018

Cancer is the leading cause of death globally and finding new therapeutic agents for cancer treatment remains a major challenge in the pursuit for a cure. This paper presents an overview on microalgae with anti-cancer activities. Microalgae are eukar...

  • Article
  • Open Access
32 Citations
7,716 Views
19 Pages

Characterization of Rhamnolipids Produced by an Arctic Marine Bacterium from the Pseudomonas fluorescence Group

  • Venke Kristoffersen,
  • Teppo Rämä,
  • Johan Isaksson,
  • Jeanette Hammer Andersen,
  • William H. Gerwick and
  • Espen Hansen

14 May 2018

The marine environment is a rich source of biodiversity, including microorganisms that have proven to be prolific producers of bioactive secondary metabolites. Arctic seas are less explored than warmer, more accessible areas, providing a promising st...

  • Review
  • Open Access
42 Citations
7,756 Views
15 Pages

Investigation of the Anti-Prostate Cancer Properties of Marine-Derived Compounds

  • Meiqi Fan,
  • Amit Kumar Nath,
  • Yujiao Tang,
  • Young-Jin Choi,
  • Trishna Debnath,
  • Eun-Ju Choi and
  • Eun-Kyung Kim

12 May 2018

This review focuses on marine compounds with anti-prostate cancer properties. Marine species are unique and have great potential for the discovery of anticancer drugs. Marine sources are taxonomically diverse and include bacteria, cyanobacteria, fung...

  • Article
  • Open Access
95 Citations
7,057 Views
19 Pages

12 May 2018

Collagen is one of the most useful biomaterials and widely applied in functional food and cosmetics. However, some consumers have paid close attention to the safety of mammalian collagens because of the outbreaks of bovine spongiform encephalopathy (...

  • Article
  • Open Access
32 Citations
8,101 Views
21 Pages

The Maxi-K (BK) Channel Antagonist Penitrem A as a Novel Breast Cancer-Targeted Therapeutic

  • Amira A. Goda,
  • Abu Bakar Siddique,
  • Mohamed Mohyeldin,
  • Nehad M. Ayoub and
  • Khalid A. El Sayed

11 May 2018

Breast cancer (BC) is a heterogeneous disease with different molecular subtypes. The high conductance calcium-activated potassium channels (BK, Maxi-K channels) play an important role in the survival of some BC phenotypes, via membrane hyperpolarizat...

  • Article
  • Open Access
45 Citations
5,846 Views
16 Pages

11 May 2018

An alginate lyase encoding gene sagl from Flavobacterium sp. H63 was codon optimized and recombinantly expressed at high level in P.pastoris through high cell-density fermentation. The highest yield of recombinant enzyme of sagl (rSAGL) in yeast cult...

  • Review
  • Open Access
78 Citations
9,066 Views
25 Pages

Diterpenes from the Marine Algae of the Genus Dictyota

  • Jiayun Chen,
  • Hong Li,
  • Zishuo Zhao,
  • Xue Xia,
  • Bo Li,
  • Jinrong Zhang and
  • Xiaojun Yan

11 May 2018

Species of the brown algae of the genus Dictyota are rich sources of bioactive secondary metabolites with diverse structural features. Excellent progress has been made in the discovery of diterpenes possessing broad chemical defensive activities from...

  • Article
  • Open Access
9 Citations
7,702 Views
14 Pages

10 May 2018

α-N-acetylgalactosaminidase (EC 3.2.1.49) (alpha-NaGalase) catalyzes the hydrolysis of N-acetamido-2-deoxy-α-d-galactoside residues from non-reducing ends of various complex carbohydrates and glycoconjugates. It is known that human cancer...

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Mar. Drugs - ISSN 1660-3397