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Mar. Drugs 2018, 16(5), 160; https://doi.org/10.3390/md16050160

Investigation of the Anti-Prostate Cancer Properties of Marine-Derived Compounds

1
Division of Food Bioscience, College of Biomedical and Health Sciences, Konkuk University, Chungju 27478, Korea
2
School of Bio-Science and Food Engineering, Changchun University of Science and Technology, Changchun 130-600, China
3
Department of Food Science and Biotechnology, Dongguk University, Goyang 10326, Korea
4
Department of Physical Education, College of Education, Daegu Catholic University, Gyeongsan 38430, Korea
These authors contributed equally to this work.
*
Author to whom correspondence should be addressed.
Received: 8 April 2018 / Revised: 30 April 2018 / Accepted: 9 May 2018 / Published: 12 May 2018
(This article belongs to the Collection Marine Compounds and Cancer)
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Abstract

This review focuses on marine compounds with anti-prostate cancer properties. Marine species are unique and have great potential for the discovery of anticancer drugs. Marine sources are taxonomically diverse and include bacteria, cyanobacteria, fungi, algae, and mangroves. Marine-derived compounds, including nucleotides, amides, quinones, polyethers, and peptides are biologically active compounds isolated from marine organisms such as sponges, ascidians, gorgonians, soft corals, and bryozoans, including those mentioned above. Several compound classes such as macrolides and alkaloids include drugs with anti-cancer mechanisms, such as antioxidants, anti-angiogenics, antiproliferatives, and apoptosis-inducing drugs. Despite the diversity of marine species, most marine-derived bioactive compounds have not yet been evaluated. Our objective is to explore marine compounds to identify new treatment strategies for prostate cancer. This review discusses chemically and pharmacologically diverse marine natural compounds and their sources in the context of prostate cancer drug treatment. View Full-Text
Keywords: prostate cancer; antioxidant; anti-proliferative; apoptosis; natural marine compounds prostate cancer; antioxidant; anti-proliferative; apoptosis; natural marine compounds
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Fan, M.; Nath, A.K.; Tang, Y.; Choi, Y.-J.; Debnath, T.; Choi, E.-J.; Kim, E.-K. Investigation of the Anti-Prostate Cancer Properties of Marine-Derived Compounds. Mar. Drugs 2018, 16, 160.

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