- Communication
Ultra-Fast Middle-Up Reversed Phase Liquid Chromatography Analysis of Complex Bispecific Antibodies Obtained in Less Than One Minute
- Amarande Murisier,
- Valentina D’Atri,
- Sebastian Pirner,
- Vincent Larraillet,
- Szabolcs Fekete,
- Matthew Lauber and
- Davy Guillarme
This work illustrates the benefits and limitations of using ultra-short reversed phase liquid chromatography (RPLC) columns for the characterization of various complex bispecific antibodies after prolonged thermal stress at the middle-up level of ana...