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30 Results Found

  • Article
  • Open Access
19 Citations
4,527 Views
18 Pages

29 September 2023

Fundus diseases cause damage to any part of the retina. Untreated fundus diseases can lead to severe vision loss and even blindness. Analyzing optical coherence tomography (OCT) images using deep learning methods can provide early screening and diagn...

  • Article
  • Open Access
467 Views
23 Pages

21 November 2025

Multiple ocular diseases frequently coexist in fundus images, while image quality is highly susceptible to imaging conditions and patient cooperation, often manifesting as blurring, underexposure, and indistinct lesion regions. These challenges signi...

  • Article
  • Open Access
630 Views
22 Pages

With the growing use of deep learning in medical image analysis, automated classification of fundus images is crucial for the early detection of fundus diseases. However, the complexity of fluorescein fundus angiography (FFA) images poses challenges...

  • Data Descriptor
  • Open Access
220 Citations
37,045 Views
14 Pages

Retinal Fundus Multi-Disease Image Dataset (RFMiD): A Dataset for Multi-Disease Detection Research

  • Samiksha Pachade,
  • Prasanna Porwal,
  • Dhanshree Thulkar,
  • Manesh Kokare,
  • Girish Deshmukh,
  • Vivek Sahasrabuddhe,
  • Luca Giancardo,
  • Gwenolé Quellec and
  • Fabrice Mériaudeau

3 February 2021

The world faces difficulties in terms of eye care, including treatment, quality of prevention, vision rehabilitation services, and scarcity of trained eye care experts. Early detection and diagnosis of ocular pathologies would enable forestall of vis...

  • Article
  • Open Access
4 Citations
2,435 Views
17 Pages

Discriminative-Region Multi-Label Classification of Ultra-Widefield Fundus Images

  • Van-Nguyen Pham,
  • Duc-Tai Le,
  • Junghyun Bum,
  • Seong Ho Kim,
  • Su Jeong Song and
  • Hyunseung Choo

Ultra-widefield fundus image (UFI) has become a crucial tool for ophthalmologists in diagnosing ocular diseases because of its ability to capture a wide field of the retina. Nevertheless, detecting and classifying multiple diseases within this imagin...

  • Article
  • Open Access
5 Citations
3,259 Views
24 Pages

6 February 2025

Retinal diseases account for a large fraction of global blinding disorders, requiring sophisticated diagnostic tools for early management. In this study, the author proposes a hybrid deep learning framework in the form of AdaptiveSwin-CNN that combin...

  • Article
  • Open Access
48 Citations
7,647 Views
27 Pages

Designing computer-aided diagnosis (CAD) systems that can automatically detect ocular diseases (ODs) has become an active research field in the health domain. Although the human eye might have more than one OD simultaneously, most existing systems ar...

  • Article
  • Open Access
25 Citations
5,140 Views
12 Pages

15 June 2022

Fundus diseases can cause irreversible vision loss in both eyes if not diagnosed and treated immediately. Due to the complexity of fundus diseases, the probability of fundus images containing two or more diseases is extremely high, while existing dee...

  • Article
  • Open Access
9 Citations
3,944 Views
12 Pages

22 March 2023

At present, multi-disease fundus image classification tasks still have the problems of small data volumes, uneven distributions, and low classification accuracy. In order to solve the problem of large data demand of deep learning models, a multi-dise...

  • Communication
  • Open Access
11 Citations
3,390 Views
9 Pages

Attention Mechanism-Based Glaucoma Classification Model Using Retinal Fundus Images

  • You-Sang Cho,
  • Ho-Jung Song,
  • Ju-Hyuck Han and
  • Yong-Suk Kim

19 July 2024

This paper presents a classification model for eye diseases utilizing attention mechanisms to learn features from fundus images and structures. The study focuses on diagnosing glaucoma by extracting retinal vessels and the optic disc from fundus imag...

  • Article
  • Open Access
70 Citations
6,130 Views
15 Pages

An Adoptive Threshold-Based Multi-Level Deep Convolutional Neural Network for Glaucoma Eye Disease Detection and Classification

  • Muhammad Aamir,
  • Muhammad Irfan,
  • Tariq Ali,
  • Ghulam Ali,
  • Ahmad Shaf,
  • Alqahtani Saeed S,
  • Ali Al-Beshri,
  • Tariq Alasbali and
  • Mater H. Mahnashi

Glaucoma, an eye disease, occurs due to Retinal damages and it is an ordinary cause of blindness. Most of the available examining procedures are too long and require manual instructions to use them. In this work, we proposed a multi-level deep convol...

  • Article
  • Open Access
5 Citations
2,534 Views
16 Pages

19 September 2024

The difficulty of classifying retinal fundus images with one or more illnesses present or missing is known as fundus multi-lesion classification. The challenges faced by current approaches include the inability to extract comparable morphological fea...

  • Article
  • Open Access
2 Citations
3,230 Views
26 Pages

One of the early manifestations of systemic atherosclerosis, which leads to blood circulation issues, is the enhanced arterial light reflex (EALR). Fundus images are commonly used for regular screening purposes to intervene and assess the severity of...

  • Article
  • Open Access
9 Citations
3,147 Views
23 Pages

CA-ViT: Contour-Guided and Augmented Vision Transformers to Enhance Glaucoma Classification Using Fundus Images

  • Tewodros Gizaw Tohye,
  • Zhiguang Qin,
  • Mugahed A. Al-antari,
  • Chiagoziem C. Ukwuoma,
  • Zenebe Markos Lonseko and
  • Yeong Hyeon Gu

Glaucoma, a predominant cause of visual impairment on a global scale, poses notable challenges in diagnosis owing to its initially asymptomatic presentation. Early identification is vital to prevent irreversible vision impairment. Cutting-edge deep l...

  • Article
  • Open Access
45 Citations
4,275 Views
11 Pages

23 November 2021

With recent advancements in machine learning, especially in deep learning, the prediction of eye diseases based on fundus photography using deep convolutional neural networks (DCNNs) has attracted great attention. However, studies focusing on identif...

  • Article
  • Open Access
4 Citations
3,663 Views
18 Pages

31 July 2023

Automatic classification of arteries and veins (A/V) in fundus images has gained considerable attention from researchers due to its potential to detect vascular abnormalities and facilitate the diagnosis of some systemic diseases. However, the variab...

  • Article
  • Open Access
13 Citations
8,186 Views
32 Pages

Early Detection and Classification of Diabetic Retinopathy: A Deep Learning Approach

  • Mustafa Youldash,
  • Atta Rahman,
  • Manar Alsayed,
  • Abrar Sebiany,
  • Joury Alzayat,
  • Noor Aljishi,
  • Ghaida Alshammari and
  • Mona Alqahtani

29 November 2024

Background—Diabetes is a rapidly spreading chronic disease that poses a significant risk to individual health as the population grows. This increase is largely attributed to busy lifestyles, unhealthy eating habits, and a lack of awareness abou...

  • Article
  • Open Access
11 Citations
3,368 Views
21 Pages

Self-FI: Self-Supervised Learning for Disease Diagnosis in Fundus Images

  • Toan Duc Nguyen,
  • Duc-Tai Le,
  • Junghyun Bum,
  • Seongho Kim,
  • Su Jeong Song and
  • Hyunseung Choo

Self-supervised learning has been successful in computer vision, and its application to medical imaging has shown great promise. This study proposes a novel self-supervised learning method for medical image classification, specifically targeting ultr...

  • Article
  • Open Access
41 Citations
4,176 Views
16 Pages

Diabetic retinopathy (DR) is the prime cause of blindness in people who suffer from diabetes. Automation of DR diagnosis could help a lot of patients avoid the risk of blindness by identifying the disease and making judgments at an early stage. The m...

  • Article
  • Open Access
13 Citations
5,251 Views
20 Pages

A Multi-Stage Approach for Cardiovascular Risk Assessment from Retinal Images Using an Amalgamation of Deep Learning and Computer Vision Techniques

  • Deepthi K. Prasad,
  • Madhura Prakash Manjunath,
  • Meghna S. Kulkarni,
  • Spoorthi Kullambettu,
  • Venkatakrishnan Srinivasan,
  • Madhulika Chakravarthi and
  • Anusha Ramesh

Cardiovascular diseases (CVDs) are a leading cause of mortality worldwide. Early detection and effective risk assessment are crucial for implementing preventive measures and improving patient outcomes for CVDs. This work presents a novel approach to...

  • Article
  • Open Access
334 Views
31 Pages

16 January 2026

Effective and transparent medical diagnosis relies on accurate and interpretable classification of medical images across multiple modalities. This paper introduces an explainable multi-modal image analysis framework based on a dual-stream architectur...

  • Article
  • Open Access
71 Citations
6,788 Views
20 Pages

A Novel Hybrid Approach Based on Deep CNN to Detect Glaucoma Using Fundus Imaging

  • Rabbia Mahum,
  • Saeed Ur Rehman,
  • Ofonime Dominic Okon,
  • Amerah Alabrah,
  • Talha Meraj and
  • Hafiz Tayyab Rauf

Glaucoma is one of the eye diseases stimulated by the fluid pressure that increases in the eyes, damaging the optic nerves and causing partial or complete vision loss. As Glaucoma appears in later stages and it is a slow disease, detailed screening a...

  • Article
  • Open Access
1 Citations
1,347 Views
17 Pages

29 October 2025

Background/Objectives: The prevailing paradigm in ophthalmic AI involves siloed, single-disease models, which fails to address the complexity of differential diagnosis in clinical practice. This study aimed to develop and validate a unified deep lear...

  • Article
  • Open Access
1,596 Views
35 Pages

ODDM: Integration of SMOTE Tomek with Deep Learning on Imbalanced Color Fundus Images for Classification of Several Ocular Diseases

  • Afraz Danish Ali Qureshi,
  • Hassaan Malik,
  • Ahmad Naeem,
  • Syeda Nida Hassan,
  • Daesik Jeong and
  • Rizwan Ali Naqvi

18 August 2025

Ocular disease (OD) represents a complex medical condition affecting humans. OD diagnosis is a challenging process in the current medical system, and blindness may occur if the disease is not detected at its initial phase. Recent studies showed signi...

  • Article
  • Open Access
28 Citations
4,392 Views
17 Pages

17 February 2023

The aim of this study is to develop a computer-assisted solution for the efficient and effective detection of diabetic retinopathy (DR), a complication of diabetes that can damage the retina and cause vision loss if not treated in a timely manner. Ma...

  • Feature Paper
  • Article
  • Open Access
25 Citations
4,960 Views
16 Pages

24 December 2020

Accurate segmentation of retinal blood vessels is a key step in the diagnosis of fundus diseases, among which cataracts, glaucoma, and diabetic retinopathy (DR) are the main diseases that cause blindness. Most segmentation methods based on deep convo...

  • Article
  • Open Access
20 Citations
4,622 Views
13 Pages

Data Diversity in Convolutional Neural Network Based Ensemble Model for Diabetic Retinopathy

  • Inamullah,
  • Saima Hassan,
  • Nabil A. Alrajeh,
  • Emad A. Mohammed and
  • Shafiullah Khan

The medical and healthcare domains require automatic diagnosis systems (ADS) for the identification of health problems with technological advancements. Biomedical imaging is one of the techniques used in computer-aided diagnosis systems. Ophthalmolog...

  • Article
  • Open Access
2 Citations
1,086 Views
37 Pages

17 September 2025

Background: Diabetic retinopathy (DR) is a leading cause of preventable vision impairment in individuals with diabetes. Early detection is essential, yet often hindered by subtle disease progression and reliance on manual expert screening. This study...

  • Article
  • Open Access
1 Citations
1,522 Views
31 Pages

HIRD-Net: An Explainable CNN-Based Framework with Attention Mechanism for Diabetic Retinopathy Diagnosis Using CLAHE-D-DoG Enhanced Fundus Images

  • Muhammad Hassaan Ashraf,
  • Muhammad Nabeel Mehmood,
  • Musharif Ahmed,
  • Dildar Hussain,
  • Jawad Khan,
  • Younhyun Jung,
  • Mohammed Zakariah and
  • Deema Mohammed AlSekait

8 September 2025

Diabetic Retinopathy (DR) is a leading cause of vision impairment globally, underscoring the need for accurate and early diagnosis to prevent disease progression. Although fundus imaging serves as a cornerstone of Computer-Aided Diagnosis (CAD) syste...

  • Article
  • Open Access
6 Citations
2,714 Views
12 Pages

30 October 2022

Morphological and functional changes in retinal vessels are indicators of a variety of chronic diseases, such as diabetes, stroke, and hypertension. However, without a large number of high-quality annotations, existing deep learning-based medical ima...