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34 Results Found

  • Article
  • Open Access
4 Citations
3,285 Views
11 Pages

Evaluation of Intra-Abdominal Hypertension Parameters in Patients with Acute Pancreatitis

  • Maja Stojanović,
  • Marko Đurić,
  • Irina Nenadić,
  • Nemanja Dimić,
  • Suzana Bojić and
  • Predrag Stevanović

23 May 2023

Background: Patients with acute pancreatitis develop numerous complications and organ damage due to increased intra-abdominal pressure (IAP). These extrapancreatic complications determine the clinical outcome of the disease. Materials and methods: A...

  • Review
  • Open Access
5 Citations
4,037 Views
15 Pages

24 January 2023

Intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) are associated with high morbidity and mortality. Obesity may result in increased intra-abdominal pressure (IAP) and affect clinical outcomes of patients with IAH and/or ACS....

  • Review
  • Open Access
26 Citations
6,056 Views
10 Pages

10 June 2022

Patients with severe acute pancreatitis (SAP) present complications and organ failure, which require treatment in critical care units. These extrapancreatic complications determine the clinical outcome of the disease. Intra-abdominal hypertension (IA...

  • Article
  • Open Access
2 Citations
2,431 Views
13 Pages

Differential Effects of Intra-Abdominal Hypertension and ARDS on Respiratory Mechanics in a Porcine Model

  • Benjamin Seybold,
  • Anna M. Deutsch,
  • Barbara Luise Deutsch,
  • Emilis Simeliunas,
  • Markus A. Weigand,
  • Mascha O. Fiedler-Kalenka and
  • Armin Kalenka

Background and Objectives: Intra-abdominal hypertension (IAH) and acute respiratory distress syndrome (ARDS) are common concerns in intensive care unit patients with acute respiratory failure (ARF). Although both conditions lead to impairment of glob...

  • Review
  • Open Access
2 Citations
2,973 Views
33 Pages

Acute Compartment Syndrome and Intra-Abdominal Hypertension, Decompression, Current Pharmacotherapy, and Stable Gastric Pentadecapeptide BPC 157 Solution

  • Predrag Sikiric,
  • Sven Seiwerth,
  • Anita Skrtic,
  • Mario Staresinic,
  • Sanja Strbe,
  • Antonia Vuksic,
  • Suncana Sikiric,
  • Dinko Bekic,
  • Toni Penovic and
  • Ivan Dobric
  • + 9 authors

In this study, pharmacotherapies of abdominal compartment syndrome (ACS) and intra-abdominal hypertension (IAH) in animal studies were reviewed from the perspective of ACS/IAH as failed cytoprotection issues, as non-specific injuries, and from the po...

  • Article
  • Open Access
21 Citations
1,312 Views
7 Pages

15 June 2008

Objective. The objectives of this study were to determine the incidence of intraabdominal hypertension in patients after major abdominal surgery and to evaluate the correlation of intra-abdominal pressure with fluid balance and systemic inflammatory...

  • Brief Report
  • Open Access
9 Citations
5,092 Views
8 Pages

Assessment of Intra-Abdominal Pressure with a Novel Continuous Bladder Pressure Monitor—A Clinical Validation Study

  • Liat Iacubovici,
  • Dana Karol,
  • Yuval Baar,
  • Avi Beri,
  • Haim Herzberg,
  • Shiri Zarour,
  • Or Goren and
  • Barak Cohen

30 January 2023

Introduction: Intra-abdominal hypertension and the resulting abdominal compartment syndrome are serious complications of severely ill patients. Diagnosis requires an intra-abdominal pressure (IAP) measurement, which is currently cumbersome and underu...

  • Review
  • Open Access
17 Citations
7,496 Views
17 Pages

Abdominal Compartment Syndrome in Acute Pancreatitis: A Narrative Review

  • Narcis Octavian Zarnescu,
  • Ioana Dumitrascu,
  • Eugenia Claudia Zarnescu and
  • Radu Costea

Abdominal compartment syndrome (ACS) represents a severe complication of acute pancreatitis (AP), resulting from an acute and sustained increase in abdominal pressure >20 mmHg, in association with new organ dysfunction. The harmful effect of high...

  • Article
  • Open Access
4 Citations
2,825 Views
12 Pages

Evaluation of the TraumaGuard Balloon-in-Balloon Catheter Design for Intra-Abdominal Pressure Monitoring: Insights from Pig and Human Cadaver Studies

  • Salar Tayebi,
  • Tim McKinney,
  • Cynthia McKinney,
  • Dipak Delvadia,
  • Marc-Alan Levine,
  • Edward S. Spofford,
  • Luca Malbrain,
  • Johan Stiens,
  • Wojciech Dabrowski and
  • Manu L. N. G. Malbrain

29 October 2023

Introduction: Intra-abdominal pressure (IAP) monitoring is crucial for the detection and prevention of intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS). In the 1970s, air-filled catheters (AFCs) for urodynamic studies were...

  • Article
  • Open Access
28 Citations
5,076 Views
10 Pages

An Ingestible Electronics for Continuous and Real-Time Intraabdominal Pressure Monitoring

  • Chien-Hung Liao,
  • Chi-Tung Cheng,
  • Chih-Chi Chen,
  • Uei-Ming Jow,
  • Chun-Hung Chen,
  • Yen-Liang Lai,
  • Ya-Chuan Chen and
  • Dong-Ru Ho

24 December 2020

Abdominal compartment syndrome can be treated through decompressive surgery if intraabdominal hypertension (IAH) can be detected in time. Treatment delays due to manual, conventional intravesical pressure (IVP) monitoring using a Foley catheter have...

  • Review
  • Open Access
36 Citations
15,199 Views
39 Pages

Fluid Management, Intra-Abdominal Hypertension and the Abdominal Compartment Syndrome: A Narrative Review

  • Rita Jacobs,
  • Robert D. Wise,
  • Ivan Myatchin,
  • Domien Vanhonacker,
  • Andrea Minini,
  • Michael Mekeirele,
  • Andrew W. Kirkpatrick,
  • Bruno M. Pereira,
  • Michael Sugrue and
  • Manu L. N. G. Malbrain
  • + 17 authors

6 September 2022

Background: General pathophysiological mechanisms regarding associations between fluid administration and intra-abdominal hypertension (IAH) are evident, but specific effects of type, amount, and timing of fluids are less clear. Objectives: This revi...

  • Article
  • Open Access
2 Citations
2,316 Views
15 Pages

24 March 2023

Background: For a long time, trans-femoral venous pressure (FVP) measurement was considered a simple alternative for estimating intra-abdominal pressure (IAP). Since intravesical [IVP] and intragastric [IGP] pressure measurements are sometimes contra...

  • Article
  • Open Access
6 Citations
2,805 Views
14 Pages

Intra-Abdominal Hypertension and Compartment Syndrome after Pediatric Liver Transplantation: Incidence, Risk Factors and Outcome

  • Norman Junge,
  • Annika Artmann,
  • Nicolas Richter,
  • Florian W. R. Vondran,
  • Dietmar Böthig,
  • Michael Sasse,
  • Harald Köditz,
  • Ulrich Baumann,
  • Philipp Beerbaum and
  • Torsten Kaussen

18 December 2022

In pediatric liver transplantation (pLT), the risk for the manifestation and relevance of intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) is high. This observational study aimed to evaluate the incidence, relevance and ris...

  • Article
  • Open Access
8 Citations
5,392 Views
41 Pages

Stable Gastric Pentadecapeptide BPC 157 Therapy: Effect on Reperfusion Following Maintained Intra-Abdominal Hypertension (Grade III and IV) in Rats

  • Marijan Tepes,
  • Ivan Krezic,
  • Hrvoje Vranes,
  • Ivan Maria Smoday,
  • Luka Kalogjera,
  • Helena Zizek,
  • Vlasta Vukovic,
  • Katarina Oroz,
  • Katarina Kasnik Kovac and
  • Predrag Sikiric
  • + 15 authors

2 November 2023

Given in reperfusion, the use of stable gastric pentadecapeptide BPC 157 is an effective therapy in rats. It strongly counteracted, as a whole, decompression/reperfusion-induced occlusion/occlusion-like syndrome following the worst circumstances of a...

  • Systematic Review
  • Open Access
13 Citations
7,142 Views
15 Pages

Systematic Review of Diagnostic Sensors for Intra-Abdominal Pressure Monitoring

  • Chien-Hung Liao,
  • Chi-Tung Cheng,
  • Chih-Chi Chen,
  • Yu-Hsin Wang,
  • Hsin-Tzu Chiu,
  • Cheng-Chun Peng,
  • Uei-Ming Jow,
  • Yen-Liang Lai,
  • Ya-Chuan Chen and
  • Dong-Ru Ho

15 July 2021

Intra-abdominal pressure (IAP) is defined as the steady-state pressure within the abdominal cavity. Elevated IAP has been implicated in many medical complications. This article reviews the current state-of-the-art in innovative sensors for the measur...

  • Article
  • Open Access
29 Citations
9,321 Views
11 Pages

Stretchable Capacitive Pressure Sensing Sleeve Deployable onto Catheter Balloons towards Continuous Intra-Abdominal Pressure Monitoring

  • Kirthika Senthil Kumar,
  • Zongyuan Xu,
  • Manivannan Sivaperuman Kalairaj,
  • Godwin Ponraj,
  • Hui Huang,
  • Chi-Fai Ng,
  • Qing Hui Wu and
  • Hongliang Ren

14 May 2021

Intra-abdominal pressure (IAP) is closely correlated with intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) diagnoses, indicating the need for continuous monitoring. Early intervention for IAH and ACS has been proven to redu...

  • Article
  • Open Access
8 Citations
4,559 Views
15 Pages

Increased Intra-Abdominal Pressure During Laparoscopic Pneumoperitoneum Enhances Albuminuria via Renal Venous Congestion, Illustrating Pathophysiological Aspects of High Output Preeclampsia

  • Pauline Dreesen,
  • Melanie K. Schoutteten,
  • Nele Vande Velde,
  • Iris Kaminski,
  • Line Heylen,
  • Bart De Moor,
  • Manu L.N.G. Malbrain and
  • Wilfried Gyselaers

11 February 2020

Intra-abdominal hypertension (IAH) causes severe organ dysfunction. Our aim is to evaluate the effect of increased intra-abdominal pressure (IAP) on renal function, hypothesizing that venous congestion may increase proteinuria and fluid retention wit...

  • Communication
  • Open Access
12 Citations
5,156 Views
11 Pages

7 September 2021

Intra-abdominal hypertension, defined as an intra-abdominal pressure (IAP) equal to or above 12 mmHg is one of the major risk-factors for increased morbidity (organ failure) and mortality in critically ill patients. Therefore, IAP monitoring is highl...

  • Case Report
  • Open Access
3,024 Views
5 Pages

A Case Report of Pseudotumor Cerebri Syndrome with a Huge Retroperitoneal Cyst

  • Jae-Myung Kim,
  • Hyunsoo Kim,
  • Kyung Wook Kang,
  • Seong-Min Choi and
  • Man-Seok Park

29 August 2023

Background: Aside from primary pseudotumor cerebri syndrome (PTCS) with an unknown etiology (i.e., idiopathic intracranial hypertension), which typically occurs in association with obesity, several conditions including cerebral venous abnormalities,...

  • Review
  • Open Access
7 Citations
4,332 Views
10 Pages

Role of Melatonin in the Onset of Metabolic Syndrome in Women

  • Vania Miloucheva Peneva,
  • Dora Dimitrova Terzieva and
  • Mitko Dimitrov Mitkov

Metabolic syndrome (MetS) is a constellation of several associated cardiometabolic risk factors that increase the risk of developing type 2 diabetes mellitus (T2DM), cardiovascular diseases, and mortality. The role of hormonal factors in the developm...

  • Article
  • Open Access
3 Citations
2,242 Views
13 Pages

Acute Kidney Injury Secondary to Abdominal Compartment Syndrome: Biomarkers, Pressure Variability, and Clinical Outcomes

  • Harun Muğlu,
  • Eslem İnan Kahraman,
  • Erdem Sünger,
  • Ahmet Murt,
  • Ahmet Bilici and
  • Numan Görgülü

22 February 2025

Background and Objectives: Abdominal compartment syndrome (ACS) is a severe clinical condition caused by intra-abdominal hypertension (IAH), often observed in surgical and trauma patients. However, ACS can also develop in non-surgical patients with m...

  • Article
  • Open Access
5 Citations
7,313 Views
12 Pages

Nonselective Blocking of the Sympathetic Nervous System Decreases Detrusor Overactivity in Spontaneously Hypertensive Rats

  • Khae-Hawn Kim,
  • Long-Hu Jin,
  • Gwoan-Youb Choo,
  • Hun-Jae Lee,
  • Bo-Hwa Choi,
  • Jiyeon Kwak,
  • Sang-Min Yoon,
  • Chang-Shin Park and
  • Tack Lee

23 April 2012

The involuntary dual control systems of the autonomic nervous system (ANS) in the bladder of awake spontaneously hypertensive rats (SHRs) were investigated through simultaneous registrations of intravesical and intraabdominal pressures to observe det...

  • Review
  • Open Access
1 Citations
5,788 Views
18 Pages

Omphalocele and Associated Anomalies: Exploring Pulmonary Development and Genetic Correlations—A Literature Review

  • Dina Al Namat,
  • Romulus Adrian Roșca,
  • Razan Al Namat,
  • Elena Hanganu,
  • Andrei Ivan,
  • Delia Hînganu,
  • Ancuța Lupu and
  • Marius Valeriu Hînganu

Omphalocele is a rare congenital abdominal wall defect, occurring in approximately 3.38 per 10,000 pregnancies. It is characterized by the herniation of abdominal organs through the base of the umbilical cord, enclosed by a peritoneal sac. While omph...

  • Article
  • Open Access
20 Citations
9,821 Views
41 Pages

Therapy Effect of the Stable Gastric Pentadecapeptide BPC 157 on Acute Pancreatitis as Vascular Failure-Induced Severe Peripheral and Central Syndrome in Rats

  • Ivan Maria Smoday,
  • Igor Petrovic,
  • Luka Kalogjera,
  • Hrvoje Vranes,
  • Helena Zizek,
  • Ivan Krezic,
  • Slaven Gojkovic,
  • Ivan Skorak,
  • Klaudija Hriberski and
  • Predrag Sikiric
  • + 10 authors

We revealed the therapy effect of the stable gastric pentadecapeptide BPC 157 (10 μg/kg, 10 ng/kg ig or po) with specific activation of the collateral rescuing pathways, the azygos vein, on bile duct ligation in particular, and acute pancreatitis...

  • Interesting Images
  • Open Access
3 Citations
2,442 Views
6 Pages

Transarterial Embolization of Ruptured Pancreaticoduodenal Artery Pseudoaneurysm Related to Chronic Pancreatitis

  • Lucian Mărginean,
  • Adrian Vasile Mureșan,
  • Emil Marian Arbănași,
  • Cătălin Mircea Coșarcă,
  • Eliza Mihaela Arbănași,
  • Eliza Russu,
  • Rares Cristian Filep and
  • Réka Kaller

We presented a 67-year-old woman with lightheadedness, diaphoresis, and acute epigastric and right hypochondrium pain, with a past medical history including stage 2 essential hypertension, chronic ischemic cardiomyopathy, and class 1 obesity. An abdo...

  • Article
  • Open Access
9 Citations
8,565 Views
18 Pages

Revealing Edible Bird Nest as Novel Functional Foods in Combating Metabolic Syndrome: Comprehensive In Silico, In Vitro, and In Vivo Studies

  • Happy Kurnia Permatasari,
  • Queen Intan Permatasari,
  • Nurpudji Astuti Taslim,
  • Dionysius Subali,
  • Rudy Kurniawan,
  • Reggie Surya,
  • Faqrizal Ria Qhabibi,
  • Melvin Junior Tanner,
  • Siti Chairiyah Batubara and
  • Fahrul Nurkolis
  • + 8 authors

6 September 2023

Metabolic dysfunction, which includes intra-abdominal adiposity, glucose intolerance, insulin resistance, dyslipidemia, and hypertension, manifests into metabolic syndrome and related diseases. Therefore, the discovery of new therapies in the fight a...

  • Article
  • Open Access
6 Citations
3,577 Views
10 Pages

Retrospective Study of Indications and Outcomes of Open Abdomen with Negative Pressure Wound Therapy Technique for Abdominal Sepsis in a Tertiary Referral Centre

  • Francesco Prete,
  • Giuseppe Massimiliano De Luca,
  • Alessandro Pasculli,
  • Giovanna Di Meo,
  • Elisabetta Poli,
  • Lucia Ilaria Sgaramella,
  • Piercarmine Panzera,
  • Francesco Vittore,
  • Antonella Filoia and
  • Angela Gurrado
  • + 2 authors

28 October 2022

In patients with advanced sepsis from abdominal disease, the open abdomen (OA) technique as part of a damage control surgery (DCS) approach enables relook surgery to control infection, defer intestinal anastomosis, and prevent intra-abdominal hyperte...

  • Article
  • Open Access
3 Citations
5,637 Views
10 Pages

DXA Android-to-Gynoid Ratio and Cardiovascular Risk Assessment in Age and BMI Propensity-Matched Early Postmenopausal Women

  • Irina Manuela Nistor,
  • Simona Fica,
  • Sorina Carmen Martin,
  • Theodor Mustata,
  • Theodor Eugen Oprea,
  • Anca Elena Sirbu and
  • Carmen Gabriela Barbu

4 July 2024

Background and Objectives: The literature suggests that physiological menopause (MP) seems linked with increased adiposity with a preference for intra-abdominal fat accumulation, greater than what can be attributed only by aging, which could magnify...

  • Article
  • Open Access
1 Citations
5,808 Views
13 Pages

25 April 2024

Background: In hemodynamically unstable patients, the passive leg raise (PLR) test is recommended for use as a self-fluid challenge for predicting preload responsiveness. However, to interpret the hemodynamic effects and reliability of the PLR, the m...

  • Article
  • Open Access
2,054 Views
14 Pages

Assessing the Impact of the Prone Position on Acute Kidney Injury

  • Eden Ezra,
  • Itai Hazan,
  • Dana Braiman,
  • Rachel Gaufberg,
  • Jonathan Taylor,
  • Adva Alyagon,
  • Amit Shira Babievb and
  • Lior Fuchs

19 January 2025

Background: Prone positioning is a standard intervention in managing patients with severe acute respiratory distress syndrome (ARDS) and is known to improve oxygenation. However, its effects on other organs, particularly the kidneys, are less well un...

  • Case Report
  • Open Access
371 Views
9 Pages

Takotsubo Syndrome After Surgical Treatment of Liver Abscess: A Case Report and Literature Review

  • Aigerim Tanyrbergenova,
  • Zhandos Burkitbayev,
  • Asel Zhumabekova,
  • Daulet Marat,
  • Damesh Orazbayeva,
  • Bekkozha Yeskendirov and
  • Dinara Zharlyganova

Background: Takotsubo cardiomyopathy (TTC), also known as stress-induced cardiomyopathy, is an acute but reversible form of left ventricular dysfunction, most commonly triggered by physical or emotional stress. Although well documented in cardiology...

  • Article
  • Open Access
4 Citations
1,637 Views
8 Pages

The Effect of Esophagogastroduodenoscopy on Intraocular Pressure

  • Maddalena De Bernardo,
  • Antonella Santonicola,
  • Marco Gioia,
  • Livio Vitiello,
  • Ferdinando Cione,
  • Sergio Pagliarulo,
  • Paola Iovino and
  • Nicola Rosa

21 February 2024

Background: Esophagogastroduodenoscopy (EGD) is an endoscopic examination of the upper gastrointestinal tract that requires insufflation with gas, leading to intra-abdominal hypertension (IAH). There is evidence suggesting that IAH positively correla...

  • Article
  • Open Access
4 Citations
4,584 Views
19 Pages

In Vitro Validation of a Novel Continuous Intra-Abdominal Pressure Measurement System (TraumaGuard)

  • Salar Tayebi,
  • Robert Wise,
  • Ashkan Zarghami,
  • Luca Malbrain,
  • Ashish K. Khanna,
  • Wojciech Dabrowski,
  • Johan Stiens and
  • Manu L. N. G. Malbrain

28 September 2023

Introduction: Intra-abdominal pressure (IAP) has been recognized as an important vital sign in critically ill patients. Due to the high prevalence and incidence of intra-abdominal hypertension in surgical (trauma, burns, cardiac) and medical (sepsis,...

  • Review
  • Open Access
365 Views
16 Pages

Transcranial Color Doppler for Assessing Cerebral Venous Outflow in Critically Ill and Surgical Patients

  • Amedeo Bianchini,
  • Giovanni Vitale,
  • Gabriele Melegari,
  • Matteo Cescon,
  • Matteo Ravaioli,
  • Elena Zangheri,
  • Maria Francesca Scuppa,
  • Stefano Tigano and
  • Antonio Siniscalchi

In recent years, Transcranial Color Doppler (TCCD) has gained increasing recognition as a non-invasive neuromonitoring tool. However, there remains a strong tendency to view arterial TCCD as the ‘stethoscope for the brain,’ while the asse...