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17 Results Found

  • Review
  • Open Access
248 Views
2 Pages

Das Happy-Heart-Syndrom: Positive Emotionen und Takotsubo-Syndrom

  • Victoria L. Cammann,
  • Christian Templin and
  • Jelena-R. Ghadri

Takotsubo syndrome (TTS) is an underestimated acute heart failure syndrome masquerading as acute myocardial infarction at presentation and mostly affecting postmenopausal women. As TTS is often precipitated by emotional stress especially after negati...

  • Opinion
  • Open Access
2,438 Views
8 Pages

31 December 2025

Takotsubo syndrome (TTS), popularly known as “broken heart syndrome”, is a type of reversible but not benign acute heart failure condition of unknown etiology, usually triggered by physical or emotional stress, affecting primarily elderly...

  • Systematic Review
  • Open Access
5 Citations
5,192 Views
11 Pages

Takotsubo Syndrome or Peripartum Cardiomyopathy? Depends on Who You Are Talking to

  • Abigail O. Falola,
  • Naveed Razvi,
  • Ruta Gada,
  • David R. Thompson and
  • Colin R. Martin

5 September 2024

Takotsubo syndrome (otherwise known as broken-heart syndrome or left ventricular apical ballooning) is a rare cause of reversible heart failure that predominantly affects postmenopausal women. It was first described by Japanese researchers in the 199...

(This article belongs to the Section Health Psychology)
  • Review
  • Open Access
17 Citations
12,721 Views
27 Pages

Broken Heart Syndrome: Evolving Molecular Mechanisms and Principles of Management

  • Yashendra Sethi,
  • Hamsa Murli,
  • Oroshay Kaiwan,
  • Vidhi Vora,
  • Pratik Agarwal,
  • Hitesh Chopra,
  • Inderbir Padda,
  • Manasa Kanithi,
  • Mihaela Simona Popoviciu and
  • Simona Cavalu

24 December 2022

Broken Heart Syndrome, also known as Takotsubo Syndrome (TS), is sudden and transient dysfunction of the left and/or right ventricle which often mimics Acute Coronary Syndrome (ACS). Japan was the first country to describe this syndrome in the 1990s,...

(This article belongs to the Section Cardiology)
  • Review
  • Open Access
9 Citations
5,796 Views
19 Pages

Takotsubo Syndrome and Gender Differences: Exploring Pathophysiological Mechanisms and Clinical Differences for a Personalized Approach in Patient Management

  • Simona Giubilato,
  • Giuseppina Maura Francese,
  • Maria Teresa Manes,
  • Roberta Rossini,
  • Roberta Della Bona,
  • Laura Gatto,
  • Antonio Di Monaco,
  • Filippo Zilio,
  • Nicola Gasparetto and
  • Fabrizio Oliva
  • + 11 authors

21 August 2024

Takotsubo syndrome (TTS), also known as the broken-heart syndrome, is a reversible condition typically observed in female patients presenting for acute coronary syndromes (ACS). Despite its increasing incidence, TTS often remains undiagnosed due to i...

(This article belongs to the Special Issue Diagnosis, Treatment and Prognosis of Coronary Heart Disease)
  • Article
  • Open Access
16 Citations
4,735 Views
13 Pages

The Broken Heart: The Role of Life Events in Takotsubo Syndrome

  • Maria Casagrande,
  • Giuseppe Forte,
  • Francesca Favieri,
  • Francesca Agostini,
  • Jasmine Giovannoli,
  • Luca Arcari,
  • Ilaria Passaseo,
  • Raffaella Semeraro,
  • Giovanni Camastra and
  • Luca Cacciotti
  • + 2 authors

26 October 2021

The onset of Takotsubo syndrome (TTS), also known as stress cardiomyopathy, is thought to be associated with some life events. This study focuses on clarifying life event characteristics and the role of triggers in the onset of TTS. Participants with...

(This article belongs to the Section Cardiology)
  • Systematic Review
  • Open Access
26 Citations
6,169 Views
15 Pages

Takotsubo Cardiomyopathy in Cancer Patients Treated with Immune Checkpoint Inhibitors: A Systematic Review and Meta-Summary of Included Cases

  • Ioannis P. Trontzas,
  • Ioannis A. Vathiotis,
  • Konstantinos G. Kyriakoulis,
  • Amalia Sofianidi,
  • Zoi Spyropoulou,
  • Andriani Charpidou,
  • Elias A. Kotteas,
  • Konstantinos N. Syrigos and
  • ImmunoTTS Collaborative Group

6 May 2023

Background: There are emerging reports of Takotsubo syndrome (TTS) in cancer patients treated with immune checkpoint inhibitors (ICIs); however, the association of the two remains uncertain. Methods: A systematic literature review was performed in th...

(This article belongs to the Section Cancer Immunology and Immunotherapy)
  • Review
  • Open Access
8 Citations
6,402 Views
23 Pages

26 December 2025

Takotsubo syndrome (TTS) is an acute condition involving left ventricular dysfunction that may present clinically as acute coronary syndrome without obstructive coronary disease or congestive heart failure. Initially considered benign, TTS is now rec...

(This article belongs to the Section Cardiology)
  • Review
  • Open Access
15 Citations
17,650 Views
24 Pages

Broad Electrocardiogram Syndromes Spectrum: From Common Emergencies to Particular Electrical Heart Disorders

  • Anastasia Balta,
  • Alexandr Ceasovschih,
  • Victorița Șorodoc,
  • Kyriakos Dimitriadis,
  • Sara Güzel,
  • Cătălina Lionte,
  • Cristian Stătescu,
  • Radu Andy Sascău,
  • Emmanouil Mantzouranis and
  • Laurențiu Șorodoc
  • + 6 authors

22 October 2022

Electrocardiogram (ECG) still remains a very useful diagnostic method in modern cardiology. Its broad availability, noninvasiveness and good sensitivity explain why it plays a capital role in the very beginning of the process of diagnosis for every p...

(This article belongs to the Section Personalized Medical Care)
  • Review
  • Open Access
60 Citations
11,238 Views
23 Pages

Current Knowledge and Future Challenges in Takotsubo Syndrome: Part 1—Pathophysiology and Diagnosis

  • Elias Rawish,
  • Thomas Stiermaier,
  • Francesco Santoro,
  • Natale D. Brunetti and
  • Ingo Eitel

28 January 2021

First recognized in 1990, takotsubo syndrome (TTS) constitutes an acute cardiac condition that mimics acute myocardial infarction commonly in the absence of obstructive coronary artery disease; it is characterized by temporary left ventricular dysfun...

(This article belongs to the Special Issue Takotsubo Syndrome)
  • Article
  • Open Access
1 Citations
4,180 Views
12 Pages

Validation of Takotsubo Syndrome Scoring System

  • Dana Deeb,
  • Ranel Loutati,
  • Louay Taha,
  • Mohammad Karmi,
  • Akiva Brin,
  • Ofir Rabi,
  • Nir Levi,
  • Noam Fink,
  • Pierre Sabouret and
  • Elad Asher
  • + 5 authors

Background: Takotsubo syndrome (TS) mimics acute coronary syndrome in 1% to 3% of patients presenting with chest pain, ECG changes and echocardiographic transient apical wall hypokinesia. Objectives: This study aimed to validate a previously develope...

(This article belongs to the Special Issue Clinical Diagnosis and Management in Cardiology)
  • Case Report
  • Open Access
1,718 Views
6 Pages

11 January 2026

Biventricular Takotsubo cardiomyopathy (TCM) is a rare variant characterized by involvement of both the left and right ventricles. This variant is associated with greater hemodynamic instability and longer hospital stays compared to the isolated left...

  • Case Report
  • Open Access
2 Citations

Objective: To present a case of takotsubo cardiomyopathy (TTC) in the context of major neurocognitive disorder and identify important considerations for psychiatrists. Conclusions: Patients with neurocognitive disorders who are treated with antidepre...

  • Feature Paper
  • Comment
  • Open Access
2 Citations
3,691 Views
2 Pages

Takotsubo cardiomyopathy (TC) or stress-induced cardiomyopathy is also popularly referred to as “broken heart syndrome” or “apical ballooning syndrome”. [...]

  • Review
  • Open Access
607 Views
23 Pages

12 August 2026

Background/Objectives: Takotsubo cardiomyopathy (TTC), also known as “broken heart syndrome”, is an acute and reversible cardiac condition often triggered by emotional or physical stress. Increasing evidence suggests a strong comorbidity...

(This article belongs to the Section Mental Health)
  • Review
  • Open Access
1 Citations
1,742 Views
14 Pages

Takotsubo Cardiomyopathy and Stressed Heart Morphology: Molecular, Hemodynamic, and Imaging Intersections

  • Omar Atef Abdelhamid Mahmoud,
  • Boran Cagatay,
  • Nagehan Kucukler,
  • Fatih Yalcin and
  • Mario J. Garcia

28 October 2025

Takotsubo Cardiomyopathy (TTC), often referred to as stress-induced or “broken heart” syndrome, is characterized by transient left ventricular dysfunction predominantly involving apical hypokinesia and basal hyperkinesia in the absence of...

(This article belongs to the Section Cardiology)
  • Case Report
  • Open Access
1 Citations
1,847 Views
8 Pages

Empowering Early Recovery: The Role of Impella 5.5 in Takotsubo Cardiomyopathy Complicated by Cardiogenic Shock

  • Aarti Desai,
  • Jose Ruiz,
  • Anna Shapiro,
  • Rebecca Klingbeil,
  • Archer Martin and
  • Rohan Goswami

5 September 2025

Introduction: Takotsubo cardiomyopathy (TCM), also known as stress cardiomyopathy or Broken Heart Syndrome, is a reversible, transient state of myocardial dyskinesis and apical ballooning. Infrequently, TCM may progress to severe life-threatening com...

(This article belongs to the Section Cardiology)