Skip to Content

29 Results Found

  • Case Report
  • Open Access
2 Citations
9,478 Views
11 Pages

Case Report of Cerebral Sinus Thrombosis Related to Immune Thrombotic Thrombocytopenia Following Administration of ChAdOx1 nCoV-19 for Vaccination against COVID-19

  • Wojciech Szypowski,
  • Aleksander Dębiec,
  • Jarosław Świstak,
  • Maciej Nowocień,
  • Piotr Rzepecki,
  • Marcin Możański,
  • Jacek Staszewski and
  • Adam Stępień

24 January 2022

Vaccine-induced immune thrombotic thrombocytopenia (VITT) with cerebral venous sinus thrombosis (CVST) has been recently reported after vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We present a case of a patient w...

  • Case Report
  • Open Access
4,190 Views
9 Pages

Post-Traumatic Cerebral Venous Sinus Thrombosis (PtCVST) Resulting in Increased Intracranial Pressure during Early Post-Traumatic Brain Injury Period: Case Report and Narrative Literature Review

  • Athanasios Theofanopoulos,
  • Athanasia Proklou,
  • Marianna Miliaraki,
  • Ioannis Konstantinou,
  • Konstantinos Ntotsikas,
  • Nikolaos Moustakis,
  • Sofia Lazarioti,
  • Eleftherios Papadakis,
  • George Kypraios and
  • Christos Tsitsipanis
  • + 3 authors

1 September 2024

Post-traumatic cerebral venous sinus thrombosis (ptCVST) often remains underdiagnosed due to the non-specific nature of clinical signs, commonly mimicking severe traumatic brain injury (TBI) manifestations. Early recognition of this rare and potentia...

  • Article
  • Open Access
4 Citations
3,379 Views
12 Pages

Postoperative Cerebral Venous Sinus Thrombosis Following a Retrosigmoid Craniotomy—A Clinical and Radiological Analysis

  • Lukasz Przepiorka,
  • Katarzyna Wójtowicz,
  • Katarzyna Camlet,
  • Jan Jankowski,
  • Sławomir Kujawski,
  • Laretta Grabowska-Derlatka,
  • Andrzej Marchel and
  • Przemysław Kunert

Postoperative cerebral venous sinus thrombosis (CVST) is a rare complication of the retrosigmoid approach. To address the lack of literature, we performed a retrospective analysis. The thromboses were divided into those demonstrating radiological (rC...

  • Article
  • Open Access
5 Citations
6,867 Views
9 Pages

Imaging Outcomes of Emergency MRI in Patients with Suspected Cerebral Venous Sinus Thrombosis: A Retrospective Cohort Study

  • Tatu Happonen,
  • Mikko Nyman,
  • Pauli Ylikotila,
  • Ville Kytö,
  • Dan Laukka,
  • Kimmo Mattila and
  • Jussi Hirvonen

Cerebral venous sinus thrombosis (CVST) is a rare neurological emergency condition with non-specific symptoms. Imaging options to rule out CVST are computed tomography (CT) and magnetic resonance imaging (MRI). This study aimed to determine the imagi...

  • Case Report
  • Open Access
2,157 Views
7 Pages

Introduction: Heparin-induced thrombocytopenia (HIT) is an autoimmune life-threatening prothrombotic syndrome associated with low platelet count after heparin exposure. Spontaneous heparin-induced thrombocytopenia (S-HIT) is an even less frequent var...

  • Article
  • Open Access
10 Citations
4,261 Views
10 Pages

Structural Imaging Characteristic, Clinical Features and Risk Factors of Cerebral Venous Sinus Thrombosis: A Prospective Cross-Sectional Analysis from a Tertiary Care Hospital in Pakistan

  • Safia Bano,
  • Muhammad Umer Farooq,
  • Sarwat Nazir,
  • Ayesha Aslam,
  • Adnan Tariq,
  • Muhammad Athar Javed,
  • Habib Rehman and
  • Ahsan Numan

Cerebral venous sinus thrombosis (CVST) is a rare cause of stroke that accounts for 0.5–1.0% of all strokes. Clinical presentation, predisposing factors, neuroimaging findings, and outcomes of CVST are extremely diverse, which causes a high index of...

  • Systematic Review
  • Open Access
5 Citations
4,568 Views
15 Pages

Rare Causes of Cerebral Venus Sinus Thrombosis: A Systematic Review

  • Rafaella Theologou,
  • Antonios Nteveros,
  • Artemios Artemiadis and
  • Konstantinos Faropoulos

12 May 2023

Background: Cerebral venous sinus thrombosis (CVST) is a rare manifestation of thrombosis commonly caused by thrombophilia, hormonal-related factors, non-cerebral malignancy, and hematologic diseases. The aim of this review was to identify and summar...

  • Article
  • Open Access
13 Citations
4,300 Views
12 Pages

Plasminogen Activator Inhibitor-1 (PAI-1) Gene Polymorphisms Associated with Cardiovascular Risk Factors Involved in Cerebral Venous Sinus Thrombosis

  • Anca Elena Gogu,
  • Andrei Gheorghe Motoc,
  • Alina Zorina Stroe,
  • Any Docu Axelerad,
  • Daniel Docu Axelerad,
  • Ligia Petrica and
  • Dragos Catalin Jianu

23 April 2021

Cerebral venous sinus thrombosis (CVST), accounting for less than 1% of stroke cases, is characterized by various causes, heterogeneous clinical presentation and different outcome. The plasminogen activator inhibitor-1 (PAI-1) gene polymorphisms has...

  • Article
  • Open Access
22 Citations
6,298 Views
15 Pages

MTHFR Gene Polymorphisms and Cardiovascular Risk Factors, Clinical-Imagistic Features and Outcome in Cerebral Venous Sinus Thrombosis

  • Anca Elena Gogu,
  • Dragos Catalin Jianu,
  • Victor Dumitrascu,
  • Horia Ples,
  • Alina Zorina Stroe,
  • Daniel Docu Axelerad and
  • Any Docu Axelerad

27 December 2020

Cerebral venous sinus thrombosis (CVST) as a severe neurological emergency, is represented by variable conditions in its clinic presentation, onset, risk factors, neuroimagistic features and outcome. The genetic polymorphism of the methylenetetrahydr...

  • Article
  • Open Access
15 Citations
3,536 Views
11 Pages

Mechanical Thrombectomy in Cerebral Venous Sinus Thrombosis: Reports of a Retrospective Single-Center Study

  • Farzaneh Jedi,
  • Gero Dethlefs,
  • Till-Karsten Hauser,
  • Florian Hennersdorf,
  • Annerose Mengel,
  • Ulrike Ernemann and
  • Benjamin Bender

28 October 2022

Current standard care for acute cerebral venous sinus thrombosis (CVST) includes either intravenous heparin or subcutaneous low-molecular-weight heparin, but patients with refractory CVST, despite adequate anticoagulation therapy, may benefit from me...

  • Case Report
  • Open Access
5,057 Views
5 Pages

17 January 2022

Cerebral venous sinus thrombosis (CVST) is a rare venous thromboembolic disease that affects young adults in their thirties, with a female predilection. Head trauma accounts for only 1–3% of cases among possible etiologies. Here, we present a p...

  • Article
  • Open Access
9 Citations
3,205 Views
6 Pages

Characteristics of Cerebral Sinus Venous Thrombosis Patients Presenting with Intracerebral Hemorrhage

  • Naaem Simaan,
  • Jeremy Molad,
  • Shlomi Peretz,
  • Andrei Filioglo,
  • Eitan Auriel,
  • Hen Hallevi,
  • Estelle Seyman,
  • Rani Barnea,
  • José E. Cohen and
  • Asaf Honig
  • + 1 author

17 February 2022

Patients with cerebral venous sinus thrombosis (CVST) occasionally present with intracerebral hemorrhage (ICH). In this study, we aimed to identify predictors for ICH in CVST patients. Prospective CVST databases from three academic centers were retro...

  • Article
  • Open Access
6 Citations
4,613 Views
9 Pages

Cerebral Venous Thrombosis: A Challenging Diagnosis; A New Nonenhanced Computed Tomography Standardized Semi-Quantitative Method

  • Andrea Romano,
  • Maria Camilla Rossi-Espagnet,
  • Luca Pasquini,
  • Alberto Di Napoli,
  • Francesco Dellepiane,
  • Giulia Butera,
  • Giulia Moltoni,
  • Olga Gagliardo and
  • Alessandro Bozzao

22 December 2021

Cerebral venous sinus thrombosis (CVST) on non-contrast CT (NCCT) is often challenging to detect. We retrospectively selected 41 children and 36 adults with confirmed CVST and two age-matched control groups with comparable initial symptoms. We evalua...

  • Case Report
  • Open Access
5,098 Views
8 Pages

16 April 2025

Background and Clinical Significance: The occurrence of cerebral venous sinus thrombosis (CVST), both with or without thrombocytopenia, following COVID-19 vaccination, is well documented and more common in recipients of vector vaccines. Cases of CVST...

  • Article
  • Open Access
1 Citations
4,804 Views
10 Pages

An Approximation of Heart Failure Using Cardiovascular Simulation Toolbox

  • Gabriela Ortiz-León,
  • Heiner José Barrantes-Vargas,
  • Manuel Arguedas-Sandí,
  • Jose Ángel Pacheco-Chaverri and
  • Marta Vílchez-Monge

In this paper, we present the simulation of 5 different heart failures with the help of the Cardiovascular Simulation Toolbox (CVST) proposed by O. Barnea et al. at Tel-Aviv University. This is a modified version of the CVST, proposed by G.Ortiz; her...

  • Case Report
  • Open Access
4 Citations
3,455 Views
7 Pages

Combined Methylprednisolone Pulse Therapy plus Rituximab for Treating a Rare Juvenile Steroid-Resistant Nephrotic Syndrome with Cerebral Venous Sinus Thrombosis: A Case Report

  • Hader I. Sakr,
  • Burhan Edrees,
  • Hussein Omar Taher,
  • Tuleen Talal Miliany,
  • Raneem Yasser Gazzaz,
  • Asma Omar AlRuwaithi,
  • Mohammed Fouad Alamer and
  • Mostafa E. Metawee

Background: Cerebral venous sinus thrombosis (CVST) secondary to nephrotic syndrome (NS) is rarely reported. Additionally, treating steroid-sensitive nephrotic syndrome (SSNS) that changes to steroid resistance (SRNS) is difficult, with many relapses...

  • Brief Report
  • Open Access
1 Citations
1,883 Views
9 Pages

Cranioplasty after Decompressive Craniectomy (DC) in a Patient with Intracerebral Hemorrhage after SARS-CoV-2 Vaccination-Related Vaccine-Induced Thrombotic Thrombocytopenia (VITT)—Proposal of a Management Protocol for This Rare Pathological Condition

  • Lennard Spanehl,
  • Uwe Walter,
  • Thomas Thiele,
  • Daniel Dubinski,
  • Bedjan Behmanesh,
  • Thomas M. Freiman,
  • Matthias Wittstock,
  • Patrick Schuss,
  • Hartmut Vatter and
  • Sae-Yeon Won
  • + 2 authors

14 August 2024

The COVID-19 (coronavirus disease) pandemic had a severe impact on public health worldwide. A rare but serious complication after administration of adenoviral vaccines against SARS-CoV-2 (AstraZeneca–Oxford and Johnson & Johnson) is vaccine...

  • Review
  • Open Access
26 Citations
8,418 Views
15 Pages

Cerebral Venous Sinus Thrombosis following COVID-19 Vaccination: Analysis of 552 Worldwide Cases

  • Cesare de Gregorio,
  • Luigi Colarusso,
  • Giuseppe Calcaterra,
  • Pier Paolo Bassareo,
  • Antonio Ieni,
  • Anna Teresa Mazzeo,
  • Giuseppe Ferrazzo,
  • Alberto Noto,
  • Ioanna Koniari and
  • Nicholas G. Kounis
  • + 1 author

3 February 2022

To date, billions of vaccine doses have been administered to restrain the current COVID-19 pandemic worldwide. Rare side effects, including intravascular blood clots, were reported in the general population after vaccination. Among these, cerebral ve...

  • Case Report
  • Open Access
6,795 Views
8 Pages

Cerebral Venous Sinus Thrombosis Following an mRNA COVID-19 Vaccination and Recent Oral Contraceptive Use

  • Timothy C. Frommeyer,
  • Tongfan Wu,
  • Michael M. Gilbert,
  • Garrett V. Brittain and
  • Stephen P. Fuqua

7 February 2023

Rising concerns of cerebral venous sinus thrombosis (CVST) and other forms of venous thromboembolism have been associated with the SARS-CoV-2 vaccinations. Adverse effects with vector-based vaccines are well documented in the literature, while less i...

  • Review
  • Open Access
47 Citations
15,003 Views
14 Pages

COVID-19 Vaccination and Neurological Manifestations: A Review of Case Reports and Case Series

  • Shitiz Sriwastava,
  • Kanika Sharma,
  • Syed Hassan Khalid,
  • Sakhi Bhansali,
  • Ashish K. Shrestha,
  • Mahmoud Elkhooly,
  • Samiksha Srivastava,
  • Erum Khan,
  • Shruti Jaiswal and
  • Sijin Wen

Background: With 10 vaccines approved by the WHO and nearly 48% of people fully vaccinated worldwide, we have observed several individual case studies of neurological manifestations post-COVID-19 vaccination. Through this systematic review, we aim to...

  • Review
  • Open Access
17 Citations
6,019 Views
16 Pages

26 October 2021

Serious vaccine-associated side effects are very rare. Major complications of vaccines are thrombocytopenia and thrombosis in which pathogenetic mechanism is consistent with endotheliopathy characterized by “attenuated” sepsis-like syndro...

  • Review
  • Open Access
3 Citations
3,488 Views
12 Pages

20 October 2022

Ischemic cerebrovascular disease (ICD), the most common neurological disease worldwide, can be classified based on the onset time (acute/chronic) and the type of cerebral blood vessel involved (artery or venous sinus). Classifications include acute i...

  • Case Report
  • Open Access
3 Citations
3,380 Views
8 Pages

12 January 2023

The main causes of anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis are ovarian teratoma and herpes simplex virus (HSV) encephalitis. We present a rare case of suspected anti-NMDAR encephalitis caused by corpus callosotomy (CC). An 18-year-old...

  • Article
  • Open Access
23 Citations
5,178 Views
15 Pages

Venous Thrombosis within 30 Days after Vaccination against SARS-CoV-2 in a Multinational Venous Thromboembolism Registry

  • Behnood Bikdeli,
  • David Jiménez,
  • Pablo Demelo-Rodriguez,
  • Francisco Galeano-Valle,
  • José Antonio Porras,
  • Raquel Barba,
  • Cihan Ay,
  • Radovan Malý,
  • Andrei Braester and
  • for the RIETE Investigators
  • + 7 authors

18 January 2022

Background: Venous thromboembolism (VTE)—including deep vein thrombosis, pulmonary embolism, and cerebral venous sinus thrombosis (CVST)—may occur early after vaccination against the severe acute respiratory syndrome coronavirus 2 (SARS-C...

  • Case Report
  • Open Access
3 Citations
5,706 Views
7 Pages

Bilateral Abducens Nerve Palsy Due to Extensive Cerebral Venous Sinus Thrombosis

  • Krunoslav Buljan,
  • Gordan Šarić,
  • Dennis Czersky Hafner and
  • Romana Perković

23 April 2019

Cerebral venous sinus thrombosis (CVST) is a relatively rare condition. We present a case of an acute aseptic thrombosis of the sagittal, transverse and sigmoid sinus in a puerperium patient with protein S deficiency. The specifics of the case includ...

  • Article
  • Open Access
6 Citations
4,409 Views
9 Pages

A Quantitative Benefit–Risk Analysis of ChAdOx1 nCoV-19 Vaccine among People under 60 in Italy

  • Raffaele Palladino,
  • Daniele Ceriotti,
  • Damiano De Ambrosi,
  • Marta De Vito,
  • Marco Farsoni,
  • Giuseppina Seminara and
  • Francesco Barone-Adesi

The Oxford-AstraZeneca ChAdOx1 nCoV-19 is a vaccine against the COVID-19 infection that was granted a conditional marketing authorization by the European Commission in January 2021. However, following a report from the Pharmacovigilance Risk Assessme...

  • Article
  • Open Access
7 Citations
17,770 Views
17 Pages

Investigation of Neurological Complications after COVID-19 Vaccination: Report of the Clinical Scenarios and Review of the Literature

  • Wei-Ping Chen,
  • Ming-Hua Chen,
  • Shih-Ta Shang,
  • Yung-Hsi Kao,
  • Kuo-An Wu,
  • Wen-Fang Chiang,
  • Jenq-Shyong Chan,
  • Hann-Yeh Shyu and
  • Po-Jen Hsiao

13 February 2023

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), broke out in 2019 and became a pandemic in 2020. Since then, vaccines have been approved to prevent severe illness. However, vaccines are ass...

  • Review
  • Open Access
11 Citations
11,504 Views
14 Pages

Vaccine-Induced Immune Thrombotic Thrombocytopenia: Clinicopathologic Features and New Perspectives on Anti-PF4 Antibody-Mediated Disorders

  • Yi Zhang,
  • Anna-Lise Bissola,
  • Jared Treverton,
  • Michael Hack,
  • Mark Lychacz,
  • Sarah Kwok,
  • Addi Arnold and
  • Ishac Nazy

9 February 2024

Introduction: Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare yet severe adverse complication first identified during the global vaccination effort against SARS-CoV-2 infection, predominantly observed following administration of t...

  • Article
  • Open Access
10 Citations
2,684 Views
23 Pages

Obesity-Dependent Association of the rs10454142 PPP1R21 with Breast Cancer

  • Irina Ponomarenko,
  • Konstantin Pasenov,
  • Maria Churnosova,
  • Inna Sorokina,
  • Inna Aristova,
  • Vladimir Churnosov,
  • Marina Ponomarenko,
  • Yuliya Reshetnikova,
  • Evgeny Reshetnikov and
  • Mikhail Churnosov

The purpose of this work was to find a link between the breast cancer (BC)-risk effects of sex hormone-binding globulin (SHBG)-associated polymorphisms and obesity. The study was conducted on a sample of 1498 women (358 BC; 1140 controls) who, depend...