Nobel Prize in Physiology or Medicine—Where Breakthroughs Meet Open Sciences

Since 1901, the Nobel Prizes have celebrated the moments when human curiosity breaks new ground — achievements that so often start small: an unexpected result, a question nobody else thought to ask, an idea pursued long before its value was clear. More than a tribute to individual achievement, the Nobel Prize honors the patience and imagination that quietly rewrite what we know, and expand what's possible for generations to come.

Join us for an upcoming webinar as our experts revisit the groundbreaking research of past laureates in physiology or medicine and examine the trends currently shaping the field. This session will offer a deeper understanding of how past breakthroughs continue to influence the direction of modern research.

Keynote Speakers:


Dr. Andre van Zundert Section Editor-in-Chief of Healthcare The University of Queensland, Australia	Prof. Dr. Süleyman Ergün Editor-in-Chief of Organoids University of Würzburg, Würzburg, Germany	Prof. Dr. Jens Coorssen Editor-in-Chief of Proteomes Institute for Globally Distributed Open Research and Education (IGDORE), Canada	Prof. Dr. Patricia Schofield Section Editor-in-Chief of Geriatrics University of Plymouth, UK

“Research Progress on Downstream Mechanisms of Glucose Metabolic Reprogramming and Its Role in the Occurrence and Progression of Type 2 Diabetes Mellitus”
by Chan Wu, Maoying Wei, Aijing Li, Qingyi Zhu, Jingyi Guo, Anning Sun, Xin Gu, Yincheng Li and Yanbing Gong
Biomedicines 2026, 14(7), 1427; https://doi.org/10.3390/biomedicines14071427

“Metformin as an Innate Immune Modulator: Metabolic and Epigenetic Reprogramming of Innate Immune Cells and Therapeutic Implications”
by Yunfeng Shi and Sheng Xia
Curr. Issues Mol. Biol. 2026, 48(6), 642; https://doi.org/10.3390/cimb48060642

“Glucagon‑like Peptide‑1 Receptor Agonists in Rheumatoid Arthritis: A Scoping Review of Metabolic, Anti‑Inflammatory, and Cardioprotective Effects”
by Simona Buonanno, Carla Gaggiano, Caterina Baldi, Luca Cantarini, Bruno Frediani and Stefano Gentileschi
J. Pers. Med. 2026, 16(6), 284; https://doi.org/10.3390/jpm16060284

“Metabolism and Metabolic Reprogramming in Laryngeal Squamous Cell Carcinoma”
by Barbara Verro, Roberta Oliveri, Giovanni Pratelli, Marianna Lauricella, Diana Di Liberto, Anna De Blasio, Daniela Carlisi and Carmelo Saraniti
Biomedicines 2026, 14(5), 959; https://doi.org/10.3390/biomedicines14050959

“Microbiota–Gut–Brain Axis Disruption, Neuroinflammation, and Potential Antioxidant‑Based Treatments in Metabolic Diseases”
by Jazmín Carro‑Rodríguez, Gabriela Ibáñez‑Cervantes, Noemí Cárdenas‑Rodríguez, Iván Ignacio‑Mejía, Exsal Manuel Albores‑Méndez, Blanca Rosalba Pardo‑Pacheco, Verónica Fernández‑Sánchez, Ana María Balboa‑Verduzco, Cecilia Adame, Eleazar Lara‑Padilla et al.
Antioxidants 2026, 15(4), 522; https://doi.org/10.3390/antiox15040522

“Integrating Untargeted Metabolomics and Transcriptomics in Mice with Pulmonary Tuberculosis to Reveal Changes in Linoleic Acid and Its Metabolism in Lung Monocyte‑Derived Macrophages”
by Yuxia Sha, Xiaoman Zhao, Hongying Zhu, Ye Li, Meilin Shao, Shenggang Ding and Haoquan Zhou
Pathogens 2026, 15(3), 254; https://doi.org/10.3390/pathogens15030254

“Integrated Multi‑Omics Analysis Reveals Dysregulated Lipid Metabolism as a Novel Mechanism in Androgenetic Alopecia”
by Xiao‑Shuang Yang, Liyang Duan, Yu‑Jie Miao, Zhongfa Lu and Ru Dai
Biomedicines 2026, 14(1), 160; https://doi.org/10.3390/biomedicines14010160

“Insulin Resistance in Bipolar Disorder: A Real‑World Cross‑Sectional Study”
by Andrea Aguglia, Matteo Meinero, Valentina Aprile, Tommaso Cerisola, Giuditta Mazzarello, Angelo Oggianu, Alessandra Costanza, Mario Amore, Andrea Amerio and Gianluca Serafini
J. Pers. Med. 2026, 16(1), 47; https://doi.org/10.3390/jpm16010047

Special Issues:

“Bone Metabolism and Skeletal Health in Diabetes” Guest Editor: Dr. Shivani Srivastava Deadline for manuscript submissions: 20 January 2027	“New Insights into Lipid Metabolism in Health and Disease” Guest Editor: Dr. Arleta Drozd Deadline for manuscript submissions: 28 February 2027

“Modeling Context‑Dependent Tumor Metabolism in 3D Systems: Implications for Functional Precision Oncology”
by Maria Virginia Giolito, Olivier Feron and Cyril Corbet
Organoids 2026, 5(3), 22; https://doi.org/10.3390/organoids5030022

“Genetic Interruption of PD‑1/PD‑L1 as an Alternative Means for Immune Checkpoint Blockade in Cancer: A Review”
by Dan Li, Jiao Lu, Qianru Li, Huan Deng and Songwei Tan
Pharmaceutics 2026, 18(6), 752; https://doi.org/10.3390/pharmaceutics18060752

“Hidden Targets in Cancer Immunotherapy: The Potential of “Dark Matter” Neoantigens”
by Francois Xavier Rwandamuriye, Alec J. Redwood, Jenette Creaney and Bruce W. S. Robinson
Vaccines 2026, 14(1), 104; https://doi.org/10.3390/vaccines14010104

“Emerging Cell‑Based Therapies for Systemic Sclerosis: From Stem Cells to CAR‑T Cells”
by Vitaly Chasov, Sabir Mukhametshin, Elvina Gilyazova, Damir Davletshin, Mariya Tikhomirova, Iuliia Topchu, Aygul Valiullina, Marcella Prete and Emil Bulatov
Curr. Issues Mol. Biol. 2026, 48(1), 76; https://doi.org/10.3390/cimb48010076

“Microbial Modulation: Unraveling the Influence of Gut Microbiota on Macrophage Polarization in Tumor Microenvironments”
by Jonathan Trejo, Hayes Koegeboehn, Farah Faizuddin, Ryan Logan, Michel Toutoungy, Aadil Sheikh, Tamer E. Fandy, Sergio Saucedo, Victor M. Vasquez, Jr., Thien Nguyen et al.
Cells 2026, 15(2), 136; https://doi.org/10.3390/cells15020136

“Adipose Stromal Cell‑Derived Cancer‑Associated Fibroblasts Promote Pancreatic Adenocarcinoma Progression Through SFRP4 Signaling”
by Joseph Rupert, Lingyi Cai, Alexes C. Daquinag, Dimitris Anastassiou and Mikhail G. Kolonin
Cancers 2026, 18(2), 233; https://doi.org/10.3390/cancers18020233

“BTK Inhibition in Hematology: From CLL/SLL to Emerging Applications Across B‑Cell and Immune Disorders”
by Andrea Duminuco, Paola De Luca, Gaia Stanzione, Laura Anastasia Caruso, Giulio Lavenia, Salvatore Scarso, Bruno Garibaldi, Fanny Erika Palumbo, Calogero Vetro and Giuseppe Alberto Palumbo
Biomolecules 2026, 16(1), 123; https://doi.org/10.3390/biom16010123

Special Issues:

“Cancer Immunotherapy: Molecular Research and Application” Guest Editors: Dr. Joaquin Marco-Brualla and Prof. Dr. Alberto Anel Deadline for manuscript submissions: 15 December 2026	“Mechanisms and Innovations in Natural Killer Cell-Based Immunotherapy” Guest Editor: Dr. Dipnarine Maharaj Deadline for manuscript submissions: 28 February 2027

“Sulbactam–Durlobactam for Carbapenem-Resistant Acinetobacter baumannii–calcoaceticus Complex”
by Francesco Nappi
Pathogens 2026, 15(4), 449; https://doi.org/10.3390/pathogens15040449

“Reduced Left Ventricular Ejection Fraction as a Marker of Vulnerability to Healthcare-Associated Infections in Coronary Care Unit Patients: A Single-Centre Cohort Study”
by Daniela-Mirela Vîrtosu, Angela Dragomir, Simina Crișan, Silvia Luca, Oana Pătru, Ruxandra-Maria Băghină, Mihai-Andrei Lazăr, Alina-Ramona Cozlac, Stela Iurciuc and Constantin-Tudor Luca
J. Clin. Med. 2026, 15(5), 1789; https://doi.org/10.3390/jcm15051789

“Dissecting Cell Death Pathways in Influenza A virus Infection: Comparative Insights from Human Models”
by Ngoc Mai Khoi Nguyen, Alison C. West, Rebecca L. Ambrose and Michelle D. Tate
Viruses 2026, 18(2), 246; https://doi.org/10.3390/v18020246

“Effect of Hantavirus Infection on the Rodent Lung Microbiome: Specific Regulatory Roles of Host Species and Virus Types”
by Yaru Xiong, Zhihui Dai, Fangling He, Rongjiao Liu, Juan Wang, Zhifei Zhan, Huayun Jia, Shengbao Chen and Liang Cai
Microorganisms 2026, 14(1), 244; https://doi.org/10.3390/microorganisms14010244

“Vaccination Against Respiratory Infections in Adults with Cancer: A Concise Guide for Clinicians”
by Kay Choong See
Vaccines 2026, 14(1), 105; https://doi.org/10.3390/vaccines14010105

“Pathogen Evasion of Humoral Innate Immunity: Coping with C-Reactive Protein and Serum Amyloid A”
by Weichen Gong, Xuefei Cheng, Julio Villena and Haruki Kitazawa
Int. J. Mol. Sci. 2026, 27(2), 1072; https://doi.org/10.3390/ijms27021072

“Antioxidant and Anti-Inflammatory Activities of Probiotic Strains”
by Olga Adriana Caliman-Sturdza, Josiana A. Vaz, Ancuta Veronica Lupaescu, Andrei Lobiuc, Codruta Bran and Roxana Elena Gheorghita
Int. J. Mol. Sci. 2026, 27(2), 1079; https://doi.org/10.3390/ijms27021079

“Reinfection-Driven Accumulation of SARS-CoV-2 Antibodies: A 36-Month Longitudinal Study in Austrian Blood Donors”
by Orkan Kartal, Alexandra Domnica Hoeggerl, Wanda Lauth, Lisa Weidner, Natalie Badstuber, Christoph Grabmer, Christof Jungbauer, Verena Nunhofer, Heidrun Neureiter, Nina Held et al.
Diagnostics 2026, 16(2), 195; https://doi.org/10.3390/diagnostics16020195

Special Issue:

“Diagnosis, Immunopathogenesis and Control of Bacterial Infections—2nd Edition”
Guest Editor: Prof. Dr. Neil Foster
Submission Deadline: 20 December 2026

“Targeting Neutrophil Extracellular Traps in Neuroinflammation: A Therapeutic Perspective on Neurodegenerative Diseases”
by Iolanda Masalskiene Costa, Alexandre Kanashiro, Giovanna Siqueira Favi Barros, Ana Julia Monteiro, Caio Santos Bonilha, Giovane Galdino and Flavio Protasio Veras
Brain Sci. 2026, 16(8), 792; https://doi.org/10.3390/brainsci16080792

“Therapeutic Advances in Major NBIA Disorders: Current Strategies and Translational Challenges”
by Floriana Cascone, Gemma Gasparini, Valeria Tiranti and Ivano Di Meo
Neurol. Int. 2026, 18(7), 133; https://doi.org/10.3390/neurolint18070133

“Targeting PD-1/PD-L1-MAPK1 Signaling by a Novel Synergistic Combination of Rivastigmine and Epigallocatechin in Alzheimer’s Disease: An Integrated In Silico Approach”
by Bhaswati Das and Marakanam Srinivasan Umashankar
Sci. Pharm. 2026, 94(3), 57; https://doi.org/10.3390/scipharm94030057

“Epstein–Barr Virus and Multiple Sclerosis: A Narrative Review on Prevention and the Concept of an Infection-Driven Disease”
by Lou Marie Salomé Schleicher, Dorotea Zivalj, Hadid Joseph Farzad Diamee, Jan Finderle, Antea Krsek and Lara Baticic
Biomedicines 2026, 14(5), 962; https://doi.org/10.3390/biomedicines14050962

“Contextual Regulation of the Kynurenine Pathway and Its Relevance for Personalized Psychiatry”
by Stephen Murata, Gregory Oxenkrug and Angelos Halaris
J. Pers. Med. 2026, 16(2), 118; https://doi.org/10.3390/jpm16020118

“Dysregulation of Immune Mediators and Synaptic Plasticity in Central Nervous System Disorders”
by Paola Imbriani, Clara D’Ambra, Roberta De Mori, Marta Ionta, Alessandro Renna and Paola Bonsi
Cells 2026, 15(2), 201; https://doi.org/10.3390/cells15020201

“Oral Dysbiosis and Neuroinflammation: Implications for Alzheimer’s, Parkinson’s and Mood Disorders”
by Laura Carolina Zavala-Medina, Joan Sebastian Salas-Leiva, Carlos Esteban Villegas-Mercado, Juan Antonio Arreguín-Cano, Uriel Soto-Barreras, Sandra Aidé Santana-Delgado, Ana Delia Larrinua-Pacheco, María Fernanda García-Vega and Mercedes Bermúdez
Microorganisms 2026, 14(1), 143; https://doi.org/10.3390/microorganisms14010143

Special Issues:

“Inflammation at the Nexus of Neurodegeneration: Cellular Mechanisms, Biomarkers and Therapeutic Targets” Guest Editor: Dr. Kirstan A. Vessey Deadline for manuscript submissions: 15 December 2026	“Advances in Neuropharmacology and Brain Injury Therapeutics” Guest Editors: Dr. Bruce X.W. Wong and Dr. Kaelyn Tan Deadline for manuscript submissions: 25 March 2027