Mechanisms and Innovations in Natural Killer Cell-Based Immunotherapy
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: 31 July 2026 | Viewed by 5
Special Issue Editor
Interests: immune-regenerative medicine; stem cell biology; G-CSF-mobilized hematopoietic stem cells and their secretome; functioning natural killer cells as well as B and T cells
Special Issue Information
Dear Colleagues,
Natural Killer (NK) cells are pivotal in innate immunity, offering rapid and potent cytotoxic responses against tumors and virally infected cells without prior sensitization. NK cell-based immunotherapy represents a transformative approach in oncology and infectious disease treatment, leveraging NK cells’ unique ability to recognize stress ligands and modulate adaptive immunity.
This Special Issue aims to highlight advances in NK cell biology, adoptive transfer strategies, CAR-NK engineering, and combination therapies to overcome tumor immune evasion.
We welcome original research and reviews addressing NK cell expansion, activation, tumor microenvironment interactions, and clinical translation. By fostering interdisciplinary collaboration, this Special Issue seeks to accelerate the development of safe and effective NK cell-based therapies for cancer and beyond.
Dr. Dipnarine Maharaj
Guest Editor
Manuscript Submission Information
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Keywords
- natural killer cells
- immunotherapy
- CAR-NK
- cancer therapy
- adoptive cell transfer
- immune modulation
- tumor microenvironment
- cell engineering
- hematologic malignancies
- viral infections
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