Special Issues

Pharmaceutics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Biodegradable Hydrogels with Potential Biomedical Applications as Drug Delivery Systems
edited by , , and Vanessa Rosciardi
submission deadline 20 Jul 2025 | 1 articles | Viewed by 1561 | Submission Open
Keywords: biodegradable and hybrid hydrogels; drug delivery; smart biomaterials; stimuli-sensitive; multi-responsive; self-healing; nanocomposites; targeted release; controlled degradation; natural polymers; functionalization and characterization strategies; renewable materials
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Novel Drug Delivery Systems for Natural Extracts
edited by
submission deadline 20 Jul 2025 | 1 articles | Viewed by 1022 | Submission Open
Keywords: natural extracts; drug delivery systems; pharmacokinetics; liposome; nanoparticles; hydrogel; controlled release; biopharmaceutics; plant extracts; animal products; marine products
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Pharmaceutical Formulation of Novel Bioactive Molecules from Marine Sources submission deadline 20 Jul 2025 | Viewed by 621 | Submission Open
Keywords: marine drugs; antimicrobial activity; antiviral activity; anticancer; drug delivery; pharmaceutical formulation; drug discovery; pharmaceutical applications
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Formulation of Recombinant Therapeutic Proteins
edited by
submission deadline 20 Jul 2025 | Viewed by 129 | Submission Open
Keywords: therapeutic proteins; biosimilars; formulation; route of administration; immunogenicity; patents; buffer-free formulations
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Nanoparticles: Technology and Therapeutic Applications in Human Infectious and Parasitic Diseases
edited by Margarita López-Viota and
submission deadline 25 Jul 2025 | 1 articles | Viewed by 2114 | Submission Open
Keywords: nanoparticles; infectious disease; parasitic disease; nanotechnology; bioenhancers; biological availability
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Liposomes Applied in Drug Delivery Systems submission deadline 30 Jul 2025 | 2 articles | Viewed by 7487 | Submission Open
Keywords: liposome; targeted drug delivery; nanomedicine; gene therapy; liposomal formulations; drug delivery; vaccine; biomaterial
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances in Dendritic Cell-Based Delivery Systems
edited by Jacqueline Oliva-Ramírez and
submission deadline 30 Jul 2025 | Viewed by 138 | Submission Open
Keywords: dendritic cells; cancer immunotherapy; targeted therapy; personalized medicine; tumor microenvironment; vaccine formulations; combination therapies; metabolic reprogramming
(This special issue belongs to the Section Drug Targeting and Design)
Pharmaceutical Applications of 3D Printing
edited by
submission deadline 31 Jul 2025 | 10 articles | Viewed by 16736 | Submission Open
Keywords: 3D printing; printlet; pharmaceutical application; dosage form; polymedication; personalized medicine
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Application of Nanomaterials in Pulmonary Drug Delivery submission deadline 31 Jul 2025 | 6 articles | Viewed by 16443 | Submission Open
Keywords: nanomaterials; lung delivery; inhalable formulations; nanoparticle properties; aerosolization; nanoparticle/mucus interactions
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Biomedical Applications: Advances in Bioengineering and Drug Delivery
edited by María Carolina Otero and
submission deadline 31 Jul 2025 | 7 articles | Viewed by 12951 | Submission Open
Keywords: biomedicine; tissue engineering; biomaterials; drug carrier; biological therapy
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Delivery System for Biomacromolecule Drugs: Design and Application
edited by and
submission deadline 31 Jul 2025 | 6 articles | Viewed by 11878 | Submission Open
Keywords: drug delivery system; biomacromolecule; protein/peptide; DNA; RNA; gene therapy; immune therapy; cancer therapy; microneedle; self-assembly
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Prodrugs and Molecular Hybrids as Innovative Strategies in Medicinal Chemistry submission deadline 31 Jul 2025 | 6 articles | Viewed by 9687 | Submission Open
Keywords: prodrugs; bioprecursors; carrier prodrugs; macromolecular prodrugs; mutual prodrugs; molecular hybrids; hybrid drugs; macromolecular hybrids; anti-inflammatory activity; antimicrobial activity; anticancer activity; biomedical applications; physicochemical characterization; pharmacokinetics profile; pharmacodynamics properties; drug targeting; drug delivery; drug discovery; drug development; toxicity
(This special issue belongs to the Section Drug Targeting and Design)
Combination Therapy Approaches for Cancer Treatment
edited by and Anita Thyagarajan
submission deadline 31 Jul 2025 | 8 articles | Viewed by 7930 | Submission Open
Keywords: combination therapy approaches; cancer chemoprevention; chemotherapeutic agents; cell signaling pathways; dietary phytochemicals; tumor resistance mechanisms; repurposed drugs; targeted therapy; immunotherapy
(This special issue belongs to the Section Drug Targeting and Design)
Advanced Strategies for Sublingual and Buccal Drug Delivery submission deadline 31 Jul 2025 | 3 articles | Viewed by 7852 | Submission Open
Keywords: permeability enhancement; sublingual absorption; buccal absorption; fast-dissolving film; fast-dissolving tablet; under the tongue solution spray; prodrugs design; pediatric formulations; drug stability; drug solubility; microneedle sublingual patch; microneedle buccal patch; solid lipid nanoparticles; nanoemulsion; nanosuspension; colloidal dispersion
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Nanoformulations for Local Treatment of Cancer, Infections and Wounds
edited by , and Tatiane Roquete Amparo
submission deadline 31 Jul 2025 | 5 articles | Viewed by 7498 | Submission Open
Keywords: nanoformulation; local application; cancer; infections; wound healing; nanotechnology; topical application; intravesical application; intratumoral administration; gel; nanoemulsion; nanoparticle
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Targeted Immune Modulation Strategies for Cancer, Infectious and Autoimmune Diseases
edited by Guangsheng Du and Lian Li
submission deadline 31 Jul 2025 | 5 articles | Viewed by 6195 | Submission Open
Keywords: immune modulation; lymphoid targeting; cancer immunotherapy; autoimmune disease; vaccine delivery
(This special issue belongs to the Section Drug Targeting and Design)
Nanomedicines for Overcoming Tumor Immunotherapy Tolerance
edited by Yaping Li
submission deadline 31 Jul 2025 | 4 articles | Viewed by 5938 | Submission Open
Keywords: tumor immunotherapy; immunotherapy tolerance; nanomedicine
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Antimicrobial Resistance and Antimicrobial Activity of Bioactive Compounds in Drug Formulations submission deadline 31 Jul 2025 | 5 articles | Viewed by 5854 | Submission Open
Keywords: new biologically active agents; drug delivery systems; antibiotic resistance; gene expression; biofilms; quorum sensing; in vitro and in vivo models
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Where Are We Now and Where Is Antimicrobial Therapy Headed?
edited by
submission deadline 31 Jul 2025 | 2 articles | Viewed by 5336 | Submission Open
Keywords: antimicrobial peptides and peptidomimetics; use of natural products; combinations of antimicrobial agents; inhibitors of virulence factors; use of nanoparticles; drug delivery systems; unconventional Drugs; phage therapy; enzybiotics
(This special issue belongs to the Section Drug Targeting and Design)
Mesenchymal Stromal Cell-Based Cell Therapy: Recent Advances and Expectations submission deadline 31 Jul 2025 | 2 articles | Viewed by 4012 | Submission Open
Keywords: cancer; exosome; mesenchymal stem cell; therapy resistance; regenerative medicine
(This special issue belongs to the Section Gene and Cell Therapy)
Chitosan-Based Nanoparticles as Carriers for Drug Delivery and Biomedical Applications
edited by Aline Martins dos Santos, Leonardo Miziara Barboza Ferreira and Eleonora Maretti
submission deadline 31 Jul 2025 | 3 articles | Viewed by 3643 | Submission Open
Keywords: chitosan; nanoparticles; pre-formulation; drug delivery; anti-cancer; anti-inflammatory; biomedical applications
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Controlled-Release Drug Delivery Systems for Anti-Inflammatory and Wound Healing Action
edited by , and Anica M. Petrović
submission deadline 31 Jul 2025 | 2 articles | Viewed by 3333 | Submission Open
Keywords: controlled drug delivery systems; systems for topical delivery; physicochemical characterization; stability studies; rheological properties; release and permeation testing; anti-inflammatory properties; wound-healing properties; natural products
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Pharmaceutical Excipients: Impact on Efficiency, Stability, and Solubility in Formulation submission deadline 31 Jul 2025 | 2 articles | Viewed by 2750 | Submission Open
Keywords: excipient; drug-excipient interaction; drug solubility; cyclodextrins; solid-state kinetics; drug delivery systems; drug release; bioavailability
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Advances in Granulation Processes in Pharmaceutical Formulation Systems
edited by Krunoslav Žižek and
submission deadline 31 Jul 2025 | 3 articles | Viewed by 2528 | Submission Open
Keywords: granulation; drug formulation; tableting; process modelling; process optimization; scale-up
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Nanocomposites as Implantable Devices or Drug Delivery Platforms: A New Insight into Treat Dental and Oral Diseases submission deadline 31 Jul 2025 | 2 articles | Viewed by 2525 | Submission Open
Keywords: dental implant; covering materials; bone substitutes; scaffold; antioxidant; anti-inflammatory; nanocomposite; controlled release; dental and oral diseases; patches and films; injectable in situ gelling formulations; biocompatibility; tissue regeneration; anticancer
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Extracellular Vesicle-Based Delivery System for Cancer and Neurodegenerative Disease Treatment
edited by Eva Costanzi, and
submission deadline 31 Jul 2025 | 2 articles | Viewed by 2452 | Submission Open
Keywords: extracellular vesicles; liposomes; cancer; neurodegenerative diseases; immunotherapy; mRNA delivery; drug delivery system; therapeutics
(This special issue belongs to the Section Gene and Cell Therapy)
Multifunctional Hydrogels for Controlled Drug Delivery
edited by
submission deadline 31 Jul 2025 | 1 articles | Viewed by 2377 | Submission Open
Keywords: multifunctional hydrogels; drug delivery; biomedical applications; targeted release; therapeutic effects
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Multi-Target Ligands Design and Targeted Drug Delivery
edited by , Slavica Oljacic and Marija Popovic Nikolic
submission deadline 31 Jul 2025 | 1 articles | Viewed by 2283 | Submission Open
Keywords: drug design; multi-target ligands; targeted drug delivery; kinases; epigenetics; cancer; neurodegeneration
(This special issue belongs to the Section Drug Targeting and Design)
Dispersed System for Controlled Drug Release and Delivery—the Path to Effective Therapeutic Solutions
edited by and Agnieszka Markowska-Radomska
submission deadline 31 Jul 2025 | 3 articles | Viewed by 1627 | Submission Open
Keywords: drug delivery systems; controlled drug release; dispersed systems; microemulsions; nanoemulsions; multiple emulsions; liposomes; nanosuspensions; self-emulsifying drug delivery system (SEDDS); colloids; micelles
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Pharmaceutical Compounding and Development of Advanced Therapy Medicinal Products: From Bench to Bedside
edited by , and Hugo Calderón
submission deadline 31 Jul 2025 | 1 articles | Viewed by 1538 | Submission Open
Keywords: ATMPs; manufacturing process; pharmaceutical compounding; product development; product characterization; process optimization; tech transfer; analytical procedures; qualification; validation; mechanism of action; CAR T cells; TILs; (viral) vectors; cell banking; regulatory aspects; hospital exemption; donor variability; comparability; point-of-care; allogenic/autologous; reconstitution/preparation for administration
(This special issue belongs to the Section Clinical Pharmaceutics)
Medical Applications of Biologic Drugs submission deadline 31 Jul 2025 | 1 articles | Viewed by 1195 | Submission Open
Keywords: monoclonal antibodies; vaccines; hormones; biologic enzymes; immunosuppressants; immunomodulators; biologic drug development; mechanism of action; safety and efficacy; therapeutic outcomes; biosimilars; gene therapy
(This special issue belongs to the Section Biologics and Biosimilars)
Synthesis of Microfluidic-Based Nanoparticles and Their Potential Applications in Drug Delivery Systems submission deadline 31 Jul 2025 | 1 articles | Viewed by 1077 | Submission Open
Keywords: microfluidics; lipids; nanomedicine; nanoparticles; drug delivery; polymers
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advanced Nanomaterials and Drug Delivery Systems for Wound Healing and Antimicrobial Therapy
edited by and Marthe Carine D. Fotsing
submission deadline 31 Jul 2025 | 3 articles | Viewed by 1034 | Submission Open
Keywords: nanotherapeutics; wound dressings; nanoparticles; nanometals; antimicrobial drugs; debridement; skin regeneration; controlled delivery systems; targeted delivery systems; bioactive 3D scaffolds; scar; nanotechnology; drug delivery; chronic wounds; acute wounds; microbial infections; HIV; viral infections; fungal infections; bacterial infections; drug resistance; nanocarriers
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
New Platform for Tuberculosis Treatment submission deadline 31 Jul 2025 | 1 articles | Viewed by 1012 | Submission Open
Keywords: tuberculosis; anti-TB drugs; drug delivery systems; nanotechnology; bioavailability; targeting
(This special issue belongs to the Section Drug Targeting and Design)
Dosage Forms in Drug Delivery: State of the Art and Future Perspectives submission deadline 31 Jul 2025 | Viewed by 649 | Submission Open
Keywords: dosage forms; drug delivery; tablets; capsules; nanoparticles; liposomes; patches; microparticles; implants; therapeutic efficacy
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Research on the Design of New Metal-Based Antitumor Drugs
edited by and Paulina Gorolomova
submission deadline 31 Jul 2025 | Viewed by 474 | Submission Open
Keywords: metal-based antitumor drugs; transition metal complexes; synthesis and physicochemical properties; structural diversity and characterization; antiproliferative effects; mechanisms of cytotoxicity and common toxicity
(This special issue belongs to the Section Drug Targeting and Design)
Biomedical Applications of Nanocarriers in Targeted Delivery of Bioactive Compounds submission deadline 31 Jul 2025 | 1 articles | Viewed by 421 | Submission Open
Keywords: absorption; bioavailability; bioactive compounds; drug delivery systems; nanoencapsulation; nanomaterials; nanocarrier systems; natural compounds; oral administration; precision therapy; targeted delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Mucosal Drug Delivery: Exploring Novel Approaches and Formulations
edited by
submission deadline 31 Jul 2025 | Viewed by 342 | Submission Open
Keywords: drug delivery; bioavailability; enhanced drug permeation; formulations
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Innovative Drug Delivery Systems for Biologics in the Treatment of Dermatological Diseases submission deadline 31 Jul 2025 | Viewed by 288 | Submission Open
Keywords: biologic treatment; skin disease; drug delivery; psoriasis; psoriasis arthritis; atopic dermatitis; hidradenitis suppurativa; chronic urticarial; bullous diseases; colagenoses; vasculitis; autoinflammatory diseases; skin cancer; drug release; dermatological pharmaceutics
(This special issue belongs to the Section Drug Delivery and Controlled Release)
New Insights in Nanoparticle-Based Psoriasis and Psoriatic Arthritis Therapy submission deadline 31 Jul 2025 | Viewed by 279 | Submission Open
Keywords: nanoparticle-based therapy; psoriasis; psoriasis arthritis
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Smart Responsive Nanocomposite as Advanced Drug Delivery System in Regenerative Tissue Engineering
edited by and Tao L. Lowe
submission deadline 31 Jul 2025 | Viewed by 186 | Submission Open
Keywords: advanced drug delivery; stimuli-responsive nanocomposite; regenerative medicine; biomaterials; gene therapy
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Recent Advances in Nucleic Acid-Based Therapeutics, Vaccines, and Drug Delivery Vehicles
edited by and Ting-Yu Shih
submission deadline 31 Jul 2025 | Viewed by 185 | Submission Open
Keywords: immunotherapy; nucleic acid-based therapeutics and delivery; RNA vaccines; biomaterials; nanomaterials; autoimmune and neurological disorders’ treatment
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Hydrogels-Based Drug Delivery System for Wound Healing submission deadline 31 Jul 2025 | Viewed by 181 | Submission Open
Keywords: controlled drug release; polymer-based hydrogels; advanced wound dressings; smart hydrogels for tissue regeneration; bioactive hydrogels; 3D-printed hydrogels for personalized wound dressings
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advanced Drug Nanocrystals
edited by Nadia Araci Bou-Chacra
submission deadline 31 Jul 2025 | Viewed by 177 | Submission Open
Keywords: preparation of drug nanocrystals: key factors affecting their stability; quality by design (QbD) approach; critical quality attributes (CQAs); and process insights for the production of drug nanocrystals; scaling up and down: industrial applications of drug nanocrystals; characterization methods for drug nanocrystals; applications of drug nanocrystals across various drug delivery routes and therapies; in vivo fate and cellular uptake of drug nanocrystals: exploring pharmacokinetics and pharmacodynamics
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advances in Inhalation Formulations: Innovations and Analytical Approaches for Pulmonary and Nasal Drug Delivery
edited by Helvécio Vinicius Antunes Rocha and
submission deadline 31 Jul 2025 | Viewed by 177 | Submission Open
Keywords: inhalation formulation; pulmonary delivery; nasal delivery
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Dendrimers in Nanomedicine: Recent Advances submission deadline 31 Jul 2025 | Viewed by 173 | Submission Open
Keywords: dendrimers; dendritic nanostructures; biological properties; diagnosis; imaging agents; carriers; drug delivery; drug therapy; nanomedicine
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Solid Dispersions for Drug Delivery: Development, Preparation and In Vitro/In Vivo Characterization submission deadline 31 Jul 2025 | Viewed by 159 | Submission Open
Keywords: solid dispersion; poorly soluble drugs; stability; dissolution properties; molecular interaction; polymers
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Recent Advances in Cancer Treatment and Drug Delivery with a Focus on Coinage Metals (Copper, Silver and Gold) submission deadline 31 Jul 2025 | Viewed by 145 | Submission Open
Keywords: cancer; copper; silver; gold; drug delivery systems; drug release; cancer therapy; chemotherapy; coinage metals
(This special issue belongs to the Section Drug Targeting and Design)
Formulation and Pharmacokinetic Studies on Liposomal Delivery
edited by Chalet Tan
submission deadline 31 Jul 2025 | Viewed by 125 | Submission Open
Keywords: liposomal delivery; liposome synthesis; liposome functionality; pharmacokinetics; targeted delivery; nanocarriers; nanomedicine; biodistribution; clinical translation
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Recent Advances in Injectable Formulations
edited by René Holm
submission deadline 31 Jul 2025 | Viewed by 123 | Submission Open
Keywords: parenteral; sterile; injectable; lyophillized; intravenous; intramuscular; subcutaneous; long-acting injectables; biologicals; pharmacokinetics
(This special issue belongs to the Section Physical Pharmacy and Formulation)
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