Novel Technologies and Challenges for the Delivery of Biomacromolecular Drugs
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".
Deadline for manuscript submissions: 20 January 2026 | Viewed by 38
Special Issue Editors
Interests: transdermal drug delivery; pulmonary drug delivery; nanocarrier; molecular pharmaceutics
Special Issues, Collections and Topics in MDPI journals
Interests: artificial intelligence; machine learning; pulmonary drug delivery; amorphous solid dispersion
Special Issues, Collections and Topics in MDPI journals
Interests: inhalable nanomedicines; drug delivery; ferroptosis; biological fate
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The delivery of biomacromolecular drugs, such as proteins and peptides, has consistently been a critical issue in the field of pharmaceutics. However, the inherent instability and large molecular weight of these drugs pose significant challenges to their effective delivery. In recent years, numerous innovative technologies have been developed to enhance the delivery efficiency of biomacromolecular drugs, including in situ hydrogels, microneedles, inhalation drug delivery systems, nanocarriers, and others. These technologies aim to achieve controlled release, maintain drug stability, and ensure precise delivery, thereby improving therapeutic efficacy. Despite these advancements, several critical challenges remain that hinder the clinical translation of these novel technologies, necessitating further investigation and attention.
The theme of this Special Issue focuses on the latest advances in novel technologies for biomacromolecular drug delivery, as well as the associated challenges. Submissions are invited to address the fabrication, characterization, evaluation, and clinical translation of biomacromolecular drug delivery systems, along with their application as strategies for treating various diseases, including both localized and systemic conditions.
Dr. Wenhao Wang
Dr. Junhuang Jiang
Dr. Zhengwei Huang
Guest Editors
Manuscript Submission Information
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Keywords
- drug delivery
- biomacromolecular drug
- drug stability
- controlled release
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