Special Issues

Pharmaceutics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Emerging Trends in Skin Delivery Systems submission deadline 25 Sep 2025 | 4 articles | Viewed by 9944 | Submission Open
Keywords: delivery systems; topical and transdermal delivery; innovative excipients; nanoparticles; skin models
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Recent Advances in Nanotechnology Therapeutics
edited by
submission deadline 30 Sep 2025 | 9 articles | Viewed by 22371 | Submission Open
Keywords: nanotechnology; cancer treatment; drug delivery systems; diagnostic imaging; personalized medicine
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Development of Physiologically Based Pharmacokinetic (PBPK) Modeling submission deadline 30 Sep 2025 | 9 articles | Viewed by 18583 | Submission Open
Keywords: physiologically based pharmacokinetic modeling (PBPK); modeling and simulations (M& S); pharmacokinetics; ADME; pharmacometrics
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Advancing Biologic Drug Development Through Physiologically Based Pharmacokinetic Modelling and Simulations
edited by and Javier Reig Lopez
submission deadline 30 Sep 2025 | 6 articles | Viewed by 9926 | Submission Open
Keywords: monoclonal antibodies; antibody-drug conjugates; bispecific antibodies; PBPK; target-mediated drug disposition; lysosomal degradation; FcRn binding; special populations
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Dosage Form Design and Delivery Therapy for Skin Disorders submission deadline 30 Sep 2025 | 3 articles | Viewed by 5938 | Submission Open
Keywords: skin therapy; skin dosage forms; skin delivery; formulations design; natural agents; polysaccharides; vegetable oils; bioactive compounds; antioxidant activity; anti-inflammatory activity; antimicrobial effect; dosage safety and efficacy
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Kinase Inhibitors: Innovative Delivery Strategies and Anticancer Potential submission deadline 30 Sep 2025 | 3 articles | Viewed by 4122 | Submission Open
Keywords: kinase inhibitors; ADME; DMPK; formulation studies; anticancer activity; drug discovery; targeted therapy; drug delivery; innovative delivery platforms
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Regenerative Biomaterials with Plant Derivatives for Skin Wound Therapy submission deadline 30 Sep 2025 | 3 articles | Viewed by 3703 | Submission Open
Keywords: biomaterials; plant derivatives; skin regeneration; wound healing; controlled delivery systems; biocompatibility; bioactivity
(This special issue belongs to the Section Drug Targeting and Design)
Preparation and Development of Amorphous Solid Dispersions
edited by and Szymon Sip
submission deadline 30 Sep 2025 | 1 articles | Viewed by 2193 | Submission Open
Keywords: amorphous solid dispersions; drug solubility enhancement; bioavailability improvement; polymer matrix stabilization; pharmaceutical formulation
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Optimizing Drug Therapy in Kidney Diseases: Effectiveness and Safety
edited by , and Ilona Idasiak-Piechocka
submission deadline 30 Sep 2025 | 2 articles | Viewed by 2150 | Submission Open
Keywords: drug– drug interactions; pharmacotherapy of kidney diseases; immunosuppression; drug-induced nephrotoxicity; glomerulonephritis; kidney transplantation; hemodialysis; peritoneal dialysis; vasculitis
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Advances in Drug Delivery Systems for Targeted Neurological Therapies
edited by Shahrzad Latifi
submission deadline 30 Sep 2025 | 1 articles | Viewed by 2026 | Submission Open
Keywords: drug delivery; brain; central nervous system; neurological disorders; blood– brain barrier; nanothechnology; nanotherapeutics; brain networks
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Recent Trends in Gel-Based Drug Delivery Systems
edited by and
submission deadline 30 Sep 2025 | 1 articles | Viewed by 1881 | Submission Open
Keywords: gel-based drug delivery systems; stimuli-responsive gel; thermosensitive gel; pH sensitive gel; self-healing gel; aerogels; hydrogels; in situ gels; microgels; organogels; oleogels; 3D printing; gel patches; mucoadhesive gels; wound dressings; tissue engineering; depot injections; implants; ophthalmic gels; biomaterials; drug delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Biomaterials and Agents: Pharmaceutical and Biomedical Applications in Dental Research, 2nd Edition submission deadline 30 Sep 2025 | 3 articles | Viewed by 1872 | Submission Open
Keywords: biomaterials; pharmaceutical agents; dentifrice and drugs; regeneration/restoration strategy; biomimetics; dental tissue; biomineralization; hybrid interfaces; protective layers and coatings; smart dental materials; bioresponsive biomaterials
(This special issue belongs to the Section Drug Targeting and Design)
Customized and Designed Micro- and Nanocarriers for Drug Delivery submission deadline 30 Sep 2025 | 1 articles | Viewed by 1446 | Submission Open
Keywords: carrier; drug delivery system; biotechnology; biological purpose; particles; fibers; nanocarrier; microcarrier
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Membrane Transport and Drug Permeation
edited by and Alekha K. Dash
submission deadline 30 Sep 2025 | 1 articles | Viewed by 1329 | Submission Open
Keywords: drug permeation; membrane transporter; membrane transport; ABC transporter; targeted delivery; membrane-transport protein; blood-brain barrier; solute carrier; ATP-binding cassette family (ABC) transporters; drug delivery
(This special issue belongs to the Section Drug Targeting and Design)
Application of Stimuli-Sensitive Hydrogel for the Treatment of Human and Animal Diseases
edited by and Elena Giuliano
submission deadline 30 Sep 2025 | 1 articles | Viewed by 1284 | Submission Open
Keywords: stimuli-responsive hydrogels; self healing; rheology; injectable systems; smart hydrogels
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Innovative Biomaterials for Precise Drug Delivery submission deadline 30 Sep 2025 | 1 articles | Viewed by 1136 | Submission Open
Keywords: drug delivery vehicles; theranostic drug delivery systems; stimuli-responsive systems; liposomes; microspheres; oleogels; organogels; emulsion-based drug carriers; core– shell systems with drug delivery functions
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Biomaterials and Agents: Pharmaceutical and Biomedical Applications in Dental and Orthopedic Research
edited by and Vukoman R. Jokanović
submission deadline 30 Sep 2025 | 1 articles | Viewed by 1051 | Submission Open
Keywords: biomaterials; dental and orthopedic applications; regenerative medicine; nanotechnology; 3D printing; drug delivery systems
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Innovative Applications of Targeted Nanocarriers and Photodynamic Therapy in the Treatment of Neurological Diseases and Tumors submission deadline 30 Sep 2025 | 1 articles | Viewed by 1002 | Submission Open
Keywords: photodynamic therapy; neurological disorders; targeted nanocarriers; brain tumors; Alzheimer’ s disease; nanomedicine; drug delivery; reactive oxygen species; nano-photosensitizers
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Development of Skin Barrier Repair Therapy Formulations for Skin Care Purposes submission deadline 30 Sep 2025 | 1 articles | Viewed by 951 | Submission Open
Keywords: skin barrier repair therapy; physiological lipid-based formulations; dermatological formulation development; stratum corneum homeostasis; novel delivery systems in skincare
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Recent Advances in Gastrointestinal Disease: Insights into Drug Delivery and Cellular and Molecular Mechanisms for Therapy submission deadline 30 Sep 2025 | 1 articles | Viewed by 910 | Submission Open
Keywords: gastrointestinal disease; drug delivery; molecular therapy; biological therapy; target therapy; molecular target; biomarkers; GI epithelial cells
(This special issue belongs to the Section Drug Delivery and Controlled Release)
In Silico Pharmacokinetic and Pharmacodynamic (PK-PD) Modeling submission deadline 30 Sep 2025 | 2 articles | Viewed by 886 | Submission Open
Keywords: physiologically based pharmacokinetics (PBPKs); population pharmacokinetics (PopPKs); quantitative systems pharmacology (QSP); Bayesian modeling; artificial intelligence in PK-PD; in silico bioequivalence; multi-objective optimization; translational pharmacokinetics
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Biomaterials-Based Drug Delivery Systems in Regenerative Medicine submission deadline 30 Sep 2025 | Viewed by 487 | Submission Open
Keywords: tissue regeneration; drug delivery systems; regenerative medicine; biomaterials; stem cell therapy; gene therapy; nanostructured biomaterials; biomimetic materials; decellularized extracellular matrices
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Compounds and Drug Delivery for Diabetes Treatment
edited by and Andile Khathi
submission deadline 30 Sep 2025 | 1 articles | Viewed by 358 | Submission Open
Keywords: diabetes; antidiabetic compounds; delivery systems; glycaemic control; insulin
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Biomarker-Guided Drug Delivery Systems and Oral Bioavailability Enhancement
edited by and
submission deadline 30 Sep 2025 | Viewed by 340 | Submission Open
Keywords: biomarker-guided delivery; personalized medicine; oral drug bioavailability; targeted drug formulations; nanocarrier; advanced drug carriers; predictive pharmacokinetics
(This special issue belongs to the Section Biopharmaceutics)
Drug Stability in Oral Administration submission deadline 30 Sep 2025 | Viewed by 275 | Submission Open
Keywords: drug stability; oral drug delivery; in vitro assessment; dissolution; oral medication lubricants; nano-formulations; biologics; stability enhancement; real-time stability assessment; drug release kinetics
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Advanced Computational Tools in Development and Assessment of Dosage Form submission deadline 30 Sep 2025 | Viewed by 234 | Submission Open
Keywords: artificial intelligence; computational tools; advanced imaging in drug development; pharmaceutical analysis; dosage form characterization; pharmaceutical process monitoring
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Cell- and Molecular-Mediated Drug Delivery for Bone and Cartilage Repair
edited by Tiago Lazzaretti Fernandes and Daniela Franco Bueno
submission deadline 30 Sep 2025 | 1 articles | Viewed by 217 | Submission Open
Keywords: drug delivery systems; drug discovery; bone repair; cartilage repair; molecular therapies; cellular approaches; tissue engineering; nanotechnology; stem cell therapy; biomaterials; osteoarthritis; therapy
(This special issue belongs to the Section Gene and Cell Therapy)
Hyaluronic Acid-Based Drug Delivery Systems
edited by and Duy-Thuc Nguyen
submission deadline 30 Sep 2025 | Viewed by 212 | Submission Open
Keywords: hyaluronan; biomaterial; hydrogel; drug delivery system; tissue engineering; regenerative medicine
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Nanomaterials for Cell Biological and Biomedical Applications
edited by
submission deadline 30 Sep 2025 | Viewed by 206 | Submission Open
Keywords: nanomaterials; drug and gene delivery; regenerative medicine; biomedical nanotechnology; cell-nanomaterial interactions; immuno-nanomedicine; functionalized nanoparticles; biosensors and diagnostics; nano-bio interfaces; translational nanomedicine
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Biocompatible Polymers: Fascinating Materials for Drug Delivery Applications submission deadline 30 Sep 2025 | Viewed by 189 | Submission Open
Keywords: biocompatible polymers; drug delivery systems; polymeric micro- and nanoparticles; controlled and/or targeted drug delivery; biodegradable polymers; smart drug carriers; nanomedicine; biomedical applications; encapsulation efficiency; stimuli-responsive polymers; pharmacokinetics and bioavailability
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Excipients in the Design and Development of Pharmaceutical Formulations
edited by Dana Emilia Man and
submission deadline 30 Sep 2025 | Viewed by 185 | Submission Open
Keywords: excipients; pharmaceutical formulation; drug delivery systems; drug stability; bioavailability; personalized medicine
(This special issue belongs to the Section Physical Pharmacy and Formulation)
New Frontiers in Therapies, Diagnostics and Biomedical Engineering of Clay-Based Materials submission deadline 30 Sep 2025 | Viewed by 162 | Submission Open
Keywords: clay and clay minerals; biomedical diagnostics; tissue engineering; controlled drug release; theranostic systems; photodynamic therapy
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Biomaterials for Drug Delivery in Radiotherapy
edited by and Fleury Augustin Nsole Biteghe
submission deadline 30 Sep 2025 | Viewed by 109 | Submission Open
Keywords: biomaterials in radiation; radiation enhancers; hydrogel in radiation; drug delivery in radiation with biomaterials; biomaterial delivery for image enhancers; biomaterial delivery to reduce irradiation-related injury; other related to the theme of this special issue
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Antibiotic Drug Delivery Systems
edited by , and Jessica V. Moore
submission deadline 10 Oct 2025 | 1 articles | Viewed by 4299 | Submission Open
Keywords: antibiotic drug delivery; antimicrobial resistance; targeted drug carriers; nanoparticles; liposomes; prodrug systems; drug solubility and stability; synergistic approaches; biofilm targeting; host– pathogen interaction; personalized antibiotic therapy
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Carbohydrate-Based Carriers for Drug Delivery, 2nd Edition submission deadline 10 Oct 2025 | 3 articles | Viewed by 4159 | Submission Open
Keywords: nanomaterials; drug delivery; release profile; polisaccharides; oligosaccharides; inclusion complexes; targeted therapy
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Emerging Drugs and Formulations for Pain Treatment
edited by Hector Isaac Rocha-González and
submission deadline 10 Oct 2025 | 5 articles | Viewed by 4073 | Submission Open
Keywords: analgesia; experimental pain treatment; preclinical models; pharmacotherapeutic management of pain; new drugs in clinical trials; drug development; psychotropic drugs; natural compounds; neuropathic Pain; chronic pain; synthetic drugs; new formulations
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Skin Care Products for Healthy and Diseased Skin
edited by Nina Dragićević
submission deadline 20 Oct 2025 | 14 articles | Viewed by 44936 | Submission Open
Keywords: skin care products; skin delivery; healthy skin; diseased skin; nanoparticle-based products; natural emulsifiers
(This special issue belongs to the Section Drug Targeting and Design)
Plant Extracts and Their Biomedical Applications submission deadline 20 Oct 2025 | 6 articles | Viewed by 12468 | Submission Open
Keywords: plant extracts/secondary metabolites; bee products; nanoparticle  drug  delivery  system; microencapsulation; biomedical applications
(This special issue belongs to the Section Drug Targeting and Design)
The Role of Free Radicals and Antioxidants in Drug Activation and Effectiveness in Different Biological Systems submission deadline 20 Oct 2025 | 2 articles | Viewed by 6366 | Submission Open
Keywords: reactive oxygen species; free radicals (superoxide and hydroxyl radicals); antioxidants; nanomaterials (micro-nano particles); drug activation; drug delivery; in vitro and in vivo studies; polymer and lipid systems; edible oils
(This special issue belongs to the Section Drug Targeting and Design)
Recent Advances in Adeno-Associated Virus-Mediated Gene Therapy and Vaccine Development submission deadline 20 Oct 2025 | 1 articles | Viewed by 2408 | Submission Open
Keywords: AAV; gene therapy; vaccines; infectious diseases; communicable diseases; genetic disorders; non-communicable diseases
(This special issue belongs to the Section Gene and Cell Therapy)
Methods of Potentially Improving Drug Permeation and Bioavailability
edited by Wihan Pheiffer, and
submission deadline 20 Oct 2025 | 3 articles | Viewed by 2282 | Submission Open
Keywords: drug permeation; bioavailablity enhancement; drug delivery systems; biological barriers; formulation strategies; in vivo; ex vivo; pharmacokinetics
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Pharmacy Compounding of Personalized Preparation for Specific Patients: Challenges and Advantages, 2nd Edition submission deadline 20 Oct 2025 | 1 articles | Viewed by 1186 | Submission Open
Keywords: formulations; drug compounding; extemporaneous preparations; galenics; quality; standard operating procedures
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Functionalized Metal Nanoparticles in Cancer Therapy submission deadline 20 Oct 2025 | Viewed by 301 | Submission Open
Keywords: functionalized metal nanoparticles; cancer therapy; targeted drug delivery; photothermal therapy; tumor targeting; biocompatibility; nanomedicine; imaging agents; precision medicine
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Targeted Drug Delivery: Innovations to Overcome Biological and Technical Barriers submission deadline 20 Oct 2025 | Viewed by 269 | Submission Open
Keywords: drug delivery; biological barriers; drug stability; patient compliance; resistance
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Recent Advances in Non-Viral Vaccine Delivery
edited by , and
submission deadline 20 Oct 2025 | Viewed by 244 | Submission Open
Keywords: vaccine delivery; adjuvant; nanoparticle; virus-like particle; emulsion; microneedle; laser; immunogenicity; vaccine safety; antigen uptake
(This special issue belongs to the Section Gene and Cell Therapy)
Ionic Liquids in Pharmaceutical and Biomedical Applications, 2nd Edition
edited by
submission deadline 30 Oct 2025 | 4 articles | Viewed by 17484 | Submission Open
Keywords: ionic liquids; deep eutectic solvents; active pharmaceutical ingredients (API); drug delivery systems; antimicrobial properties; drug and protein stabilization; nanoformulations; biosensing
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Recent Advances in Peptide and Protein-Based Drug Delivery Systems
edited by
submission deadline 30 Oct 2025 | 3 articles | Viewed by 2795 | Submission Open
Keywords: drug delivery systems; protein; peptide; nanotechnology; targeted delivery; nanocomposites
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Recent Advances on Molecular Modeling in Pharmaceutics submission deadline 30 Oct 2025 | 1 articles | Viewed by 1180 | Submission Open
Keywords: DFT; quantum mechanics; molecular mechanics; quantum chemistry; molecular dynamics; adsorption simulations; molecular modeling; pharmacokinetics; biopharmaceutics
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Drug–Drug Interactions—New Perspectives submission deadline 30 Oct 2025 | Viewed by 161 | Submission Open
Keywords: safety of therapy; cytochrome P450; pharmacokinetics; contraindication; machine learning; metabolism
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Natural Pharmaceuticals Focused on Anti-inflammatory Activities submission deadline 31 Oct 2025 | 7 articles | Viewed by 17456 | Submission Open
Keywords: anti-inflammatory properties; chemical identification of natural anti-inflammatory agents; delivery and controlled-release systems; natural extracts; mechanisms of natural anti-inflammatory agents; molecular docking; natural products; plants and fungi; structure– effect relationships
(This special issue belongs to the Section Drug Targeting and Design)
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