Special Issues

Pharmaceutics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Extemporaneous Formulations: Filling the Gap in the Pharmaceutical Industry with Personalized Medicines submission deadline 31 Oct 2025 | 10 articles | Viewed by 17326 | Submission Open
Keywords: extemporaneous; compounding; pharmaceutical; formulation; personalized; pharmacy
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Ophthalmic Drug Delivery, 3rd Edition submission deadline 31 Oct 2025 | 5 articles | Viewed by 14159 | Submission Open
Keywords: ocular pharmacokinetics; ocular drug delivery systems; ocular routs of drug administration; intravitreal administration; topical administration
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Proteases and Serpins: Therapeutic Targets for Various Diseases
edited by
submission deadline 31 Oct 2025 | 5 articles | Viewed by 11641 | Submission Open
Keywords: serpin; protease; serine protease inhibitors; disease; cancer; diabetes; cardiovascular disease; inflammatory disease; therapy; drug development; oxidative stress
(This special issue belongs to the Section Drug Targeting and Design)
Novel Approaches in the Search for Active Compounds in Drug Discovery and Development submission deadline 31 Oct 2025 | 4 articles | Viewed by 9648 | Submission Open
Keywords: drug candidates; adjuvants; multidrug resistance; organic synthesis; ADMETox; cancer research; antimicrobial agents; immunology; novel approaches; drug discovery & development; transition metals; rare earth elements; selenium; tellurium; arsenic
(This special issue belongs to the Section Drug Targeting and Design)
Advanced Nanotechnology for Combination Therapy and Diagnosis
edited by Renato Sonchini Gonçalves and Gustavo Braga
submission deadline 31 Oct 2025 | 6 articles | Viewed by 8907 | Submission Open
Keywords: nanotechnology; nanomedicine; combination therapy; noncommunicable diseases; theranostics
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Aspects and Implementation of Pharmaceutical Quality by Design, 2nd Edition submission deadline 31 Oct 2025 | 4 articles | Viewed by 7276 | Submission Open
Keywords: quality by design; identification of patient needs; process optimization; design of experiments; multivariate data analysis; machine learning; process analytical technologies; control strategy
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Advanced Drug Delivery Across the Blood–Brain Barrier
edited by and Zhen Zhao
submission deadline 31 Oct 2025 | 2 articles | Viewed by 7175 | Submission Open
Keywords: blood– brain barrier (BBB); central nervous system (CNS); drug delivery; neurological disease; nanotechnology; transport mechanism; targeted delivery; BBB permeability; glioblastoma
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances in Analysis and Modeling of Solid Drug Product submission deadline 31 Oct 2025 | 4 articles | Viewed by 4086 | Submission Open
Keywords: design-of-experiments (DoE); data-driven modeling/analysis; mechanistic modeling; hybrid modeling; uncertainty analysis; real-time monitoring/release testing; digitalization
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Advanced In Silico Methods and Digital Platforms for the Prediction of ADMET and Pharmacokinetics Properties submission deadline 31 Oct 2025 | 2 articles | Viewed by 4049 | Submission Open
Keywords: ADMET properties prediction; physiologically based pharmacokinetic (PBPK) modeling; in silico digital platform; chemoinformatics; computer-aided drug discovery; predictive toxicology
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Natural Bioactive Compounds in Micro- and Nanocarriers
edited by , and Ivana Nešić
submission deadline 31 Oct 2025 | 2 articles | Viewed by 2549 | Submission Open
Keywords: phytochemicals; natural compound; natural products; development of micro- and nano-sized delivery systems; formulation of products based on nano- and micro-systems; systems for targeted delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Protein-Based Nanoparticles: Promising Platforms for Drug Delivery
edited by Cheng Cao and Jiali Zhai
submission deadline 31 Oct 2025 | 1 articles | Viewed by 2521 | Submission Open
Keywords: nanoparticles; protein corona; drug delivery; protein interactions; cellular uptake; physicochemical properties; characterizations
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Application of Phytochemicals in Innovative Drug Delivery Systems and Formulations submission deadline 31 Oct 2025 | 1 articles | Viewed by 2142 | Submission Open
Keywords: microparticles; nanoparticles; drug delivery systems; cancer; inflammation; phytochemicals; phytotherapy; medicinal plants
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Impact of Lipid Nanoparticle Physicochemical Properties on mRNA Vaccine
edited by
submission deadline 31 Oct 2025 | 1 articles | Viewed by 1991 | Submission Open
Keywords: lipid nanoparticle formulation; ionizable lipids design; delivery of mRNA vaccines; sustained/controlled release; targeted delivery; stability and storage solutions; pharmacokinetics and pharmacodynamics
(This special issue belongs to the Section Gene and Cell Therapy)
Novel Approaches to Drug Delivery in Ophthalmic Disorders
edited by Letizia Pelusi and
submission deadline 31 Oct 2025 | 1 articles | Viewed by 1163 | Submission Open
Keywords: eye diseases; ocular drug delivery; ocular barrier; conventional therapies; innovative technologies; nanoparticle carriers; injectable hydrogels; ocular implants; gene therapy in ophthalmology
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances in Anticancer Drug Metabolism Research: Implications for Personalized Therapeutics submission deadline 31 Oct 2025 | 1 articles | Viewed by 1064 | Submission Open
Keywords: anticancer drug metabolism; personalized medicine; drug interactions; therapeutic efficacy; drug safety; pharmacogenomics
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Essential Oils: From Biological Activity to Pharmaceutical Applications submission deadline 31 Oct 2025 | 1 articles | Viewed by 1041 | Submission Open
Keywords: EOs as active chemicals; EOs’ biological activity (antimicrobial; insecticidal; herbicidal; bactericidal; and fungicidal properties); EOs encapsulation procedures; EOs for improving human health; EOs in active packaging products; polymeric networks for EOs encapsulation
(This special issue belongs to the Section Drug Targeting and Design)
Advanced Nano-Based Drug Delivery Systems for Infectious Diseases
edited by Claudio J. Salomon and Maria Celina Lamas
submission deadline 31 Oct 2025 | 1 articles | Viewed by 1013 | Submission Open
Keywords: nanomedicines; infectious disease; microorganisms; therapeutic treatments; drug delivery systems
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Nanotechnology-Driven Drug Repurposing: A Novel Strategy for Targeted Drug Delivery and Pharmacokinetic Enhancement submission deadline 31 Oct 2025 | 1 articles | Viewed by 945 | Submission Open
Keywords: nanotechnology; drug repurposing; targeted drug delivery; pharmacokinetics; nanocarriers
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Quality by Design in Pharmaceutical Manufacturing submission deadline 31 Oct 2025 | 1 articles | Viewed by 944 | Submission Open
Keywords: quality by design; critical quality attributes; pharmaceutical technology; drug product process development; process analytical technologies; patient-centric approaches; process validation; ongoing procedure performance verification; analytical quality by design; continuous manufacturing; design of experiments; clinically relevant specification; risk assessment
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Inhaled Advances: Emerging Trends in Pulmonary Drug Delivery submission deadline 31 Oct 2025 | 1 articles | Viewed by 822 | Submission Open
Keywords: pulmonary drug delivery; microparticles; nanomedicines; infectious diseases; lung targeting
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Innovations in Drug Delivery, Pharmacometrics, and Clinical Studies in Veterinary Medicine submission deadline 31 Oct 2025 | Viewed by 469 | Submission Open
Keywords: veterinary medicine; pharmacometrics; PK/PD modeling; drug delivery; dose optimization
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Smart Polymeric Nanoparticle-Based Drug Delivery Systems
edited by Amos O. Abioye
submission deadline 31 Oct 2025 | Viewed by 361 | Submission Open
Keywords: polymer therapeutics; polymeric nanocarriers; polymer– drug conjugates; smart drug delivery systems; precision-driven drug targeting; functionalized polymers; polymeric self-assembly; quality by design approaches; process optimization techniques; therapeutic efficacy
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Pharmaceutical Applications and Therapeutic Mechanisms of Substances from Plant Origin
edited by Iliya Zhelev Slavov, , and
submission deadline 31 Oct 2025 | 1 articles | Viewed by 275 | Submission Open
Keywords: natural substances; phytotherapy; phytochemistry; chromatography; pharmacokinetics; pharmacodynamics; drug delivery
(This special issue belongs to the Section Drug Targeting and Design)
Nanotechnology in Formulation of Tumor-Targeted Drug Delivery Systems submission deadline 31 Oct 2025 | Viewed by 228 | Submission Open
Keywords: nanotechnology; formulations; tumor and cancer treatment; drug delivery
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Metal Complexes as Antimicrobial Agents: Pharmacokinetics and Drug Development Implications submission deadline 31 Oct 2025 | Viewed by 202 | Submission Open
Keywords: metal complexes; antimicrobial agents; drug development; therapeutic agents; pharmacokinetics
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Medical Applications of Chitosan Nanoparticles submission deadline 31 Oct 2025 | Viewed by 173 | Submission Open
Keywords: chitosan; chitosan-based nanoparticles; drug delivery; biopolymers; polysaccharide; biomaterials; health concerns
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Technology and Preparation of Solid Dispersion for the Enhancement of Oral Bioavailability
edited by , Andreea Loredana Vonica-Tincu and
submission deadline 31 Oct 2025 | Viewed by 172 | Submission Open
Keywords: solid dispersions; poor water solubility; rational formulation design; enhancement of oral bioavailability; preparation technology
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Impacts of the Kallikrein–Kinin System in Cancer and Its Treatment: A Focus on Drug Delivery and Formulations
edited by Indiara Brusco and
submission deadline 31 Oct 2025 | Viewed by 166 | Submission Open
Keywords: cancer pathophysiology; cancer pain; adverse effects of chemotherapy; cancer-related pain mechanisms; tumor microenvironment; kininogens; kininases; kinin B1 and B2 receptors; anticancer treatment; kinin B1 and B2 receptor antagonists; drug delivery; drug formulations; nanoparticles; liposomes; polymeric micelles; prodrugs
(This special issue belongs to the Section Biologics and Biosimilars)
Innovative Modelling and Simulation Approaches in Pharmaceutical Process Engineering
edited by Claudia Cogné and
submission deadline 31 Oct 2025 | Viewed by 149 | Submission Open
Keywords: pharmaceutical process engineering; modelling and simulation; mechanistic modelling; digital twins; machine learning; process optimisation and intensification; quality by design (QbD); process analytical technology (PAT); predictive modelling; pharmaceutical manufacturing
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Medical Applications of Extracellular Vesicles submission deadline 31 Oct 2025 | Viewed by 123 | Submission Open
Keywords: extracelular vesicles; intercellular communication; EV characterization in health and disease; EV-based drug delivery systems; biomarkers
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances in Lipid, Polymeric, and Albumin-Based Drug Delivery Systems
edited by and
submission deadline 31 Oct 2025 | Viewed by 106 | Submission Open
Keywords: nanoparticle; albumin nanoparticle; human serum albumin; polymeric nanoparticle; polymeric micelle; PLGA nanoparticle; lipid nanoparticle; liposome; nanomedicine
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Recent Advances in Photodynamic Therapy for Dental Diseases
edited by Patricia Comeau
submission deadline 31 Oct 2025 | Viewed by 103 | Submission Open
Keywords: photodynamic therapy; biomaterials; nanoparticles; dental; bone tissue engineering; drug delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advancing HIV Prevention and Treatment: Pharmacokinetics, Pharmacodynamics, Toxicokinetics, Formulation and Delivery of Antiretroviral Drugs
edited by Julie B. Dumond
submission deadline 31 Oct 2025 | Viewed by 94 | Submission Open
Keywords: long-acting injectable antiretrovirals; PK/PD modeling of antiretrovirals; predictions of HIV PrEP effectiveness; antiretroviral toxicokinetics; novel drug delivery systems; novel dosing strategies; HIV treatment or prevention therapeutics in development; clinical pharmacokinetic studies in key populations; HIV drug delivery innovations; mannose receptor-targeted delivery
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Design, Development and Biomedical Applications of Hyaluronic Acid-Based Drug and Gene Delivery Systems
edited by Cristina Casadidio and Alice Spadea
submission deadline 31 Oct 2025 | Viewed by 85 | Submission Open
Keywords: hyaluronic acid; targeted drug delivery; gene delivery; CD44; nucleic acid delivery; HA conjugates; nanoparticles personalized medicine
(This special issue belongs to the Section Gene and Cell Therapy)
PLGA Micro/Nanoparticles in Drug Delivery
edited by Ilaria Arduino and
submission deadline 10 Nov 2025 | 3 articles | Viewed by 3583 | Submission Open
Keywords: micro- and nanotechnology; particle manufacturing; targeted delivery; particle characterization; biocompatibility; solubility enhancement
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Recent Advances in Hepatic-Targeted Drug Delivery Systems submission deadline 10 Nov 2025 | Viewed by 822 | Submission Open
Keywords: hepatic drug delivery; phytotherapy; nanomedicine; lipid complexes; targeted therapies; liver diseases; drug vehicles; biomaterials; hepatocellular carcinoma; liposome; polymeric nanoparticles; lipid nanoparticles; hepatic stellate cell
(This special issue belongs to the Section Drug Targeting and Design)
Pathophysiological Influences on Pharmacokinetics and Pharmacodynamics
edited by Geraldo Duarte, Fernanda de Lima Moreira and Jhohann Richard de Lima Benzi
submission deadline 20 Nov 2025 | 3 articles | Viewed by 6399 | Submission Open
Keywords: drug– disease interactions; pharmacokinetics; pharmacodynamics; pharmacotherapy
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Novel Drug Delivery Systems for the Treatment of Skin Disorders submission deadline 20 Nov 2025 | 2 articles | Viewed by 3960 | Submission Open
Keywords: drug delivery; nanoparticles; vesicular systems; 3D-printed drugs; topical dosage form; skin disorder; penetration
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Long Acting Drug Delivery Formulations
edited by Thierry Vandamme
submission deadline 20 Nov 2025 | 1 articles | Viewed by 3200 | Submission Open
Keywords: improvement in patient adherence; steady state; drug bioavailability; reduced side effect; targeted delivery; long acting; sustained release; prolonged release; pulse release; compliance
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Nanotechnology and RNA-Based Technologies Applied to Prophylaxis and Advanced Therapies
edited by and Vinicius Pinto Costa Rocha
submission deadline 20 Nov 2025 | 1 articles | Viewed by 3143 | Submission Open
Keywords: RNA-technologies; nanotechnology; messenger RNA (mRNA); interference RNA (RNAi); vaccines; treatment
(This special issue belongs to the Section Gene and Cell Therapy)
Biomaterials: Pharmaceutical Applications
edited by
submission deadline 20 Nov 2025 | 2 articles | Viewed by 2166 | Submission Open
Keywords: natural biomaterials; synthetic biomaterials; drug delivery systems; tissue engineering; disease diagnosis; wound healing
(This special issue belongs to the Section Biopharmaceutics)
“The Power of Light” in Biomedical and Pharmaceutics: New Approaches for Photodynamic Purposes submission deadline 20 Nov 2025 | 1 articles | Viewed by 720 | Submission Open
Keywords: light; photosensitizers; photochemistry; photobiology; photodynamic therapy
(This special issue belongs to the Section Drug Targeting and Design)
Recent Advances in Drug Formulation for Antiviral Therapy
edited by Chiara Medaglia
submission deadline 20 Nov 2025 | Viewed by 380 | Submission Open
Keywords: antiviral drugs development; infection; host-pathogen interactions; functional genomics
(This special issue belongs to the Section Drug Targeting and Design)
Antibody–Drug Conjugates Therapeutics submission deadline 20 Nov 2025 | Viewed by 168 | Submission Open
Keywords: antibody– drug conjugate; drug delivery; antibody; payload; linker; protein conjugation
(This special issue belongs to the Section Biologics and Biosimilars)
Drug Product Performance: Bioavailability, Relative Bioavailability and Bioequivalence, 2nd Edition
edited by
submission deadline 30 Nov 2025 | 10 articles | Viewed by 17495 | Submission Open
Keywords: bioavailability; relative bioavailability; bioequivalence; biowaivers; statistical issues; regulatory issues; in vitro– in vivo correlations; physiologically-based biopharmaceutical models; physiologically-based pharmacokinetic models; qualification of models; population pharmacokinetic models; biopharmaceutical classification system; in vitro dissolution; dissolution metrics; predictive dissolution; clinical trial simulations; clinical trial optimization; healthy subjects in BA/BE trials; patients in BA/BE trials; pharmacokinetic parameters for BA/BE assessment; narrow therapeutic index drugs; highly variable drug products; immediate-release formulations; modified-release formulations; multiphasic drug products; extravascular routes of administration
(This special issue belongs to the Section Biopharmaceutics)
Advances in Drug Delivery Systems for the Treatment of Chronic Wound Healing
edited by Carolina Martinez and María Jimena Prieto
submission deadline 30 Nov 2025 | 8 articles | Viewed by 10597 | Submission Open
Keywords: wound healing; chronic diseases; wound repair and regeneration; drug delivery; topical formulations; biomaterial; nanotechnology; wound dressing; scar
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Inorganic Nanomaterials for the Development of Drug Delivery and Biomedical Applications
edited by
submission deadline 30 Nov 2025 | 2 articles | Viewed by 6464 | Submission Open
Keywords: inorganic nanoparticles; drug delivery; disease diagnosis; disease treatment; nano-biosensor; cancer theranostics; cancer imaging
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Hybrid Nanoparticles for Cancer Therapy
edited by Jacy Gameiro
submission deadline 30 Nov 2025 | 4 articles | Viewed by 4889 | Submission Open
Keywords: hybrid nanoparticles; cancer therapy; targeted drug delivery; nanomedicine; tumor microenvironment; gene therapy; immunotherapy; diagnostics; nanomaterials
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Naturally Derived Materials-Based Drug Delivery Systems and Their Biomedical Applications
edited by and
submission deadline 30 Nov 2025 | 3 articles | Viewed by 4531 | Submission Open
Keywords: naturally derived material; drug delivery systems; tissue engineering; regenerative medicine
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances in Granulation Processes in Pharmaceutical Formulation Systems
edited by Krunoslav Žižek and
submission deadline 30 Nov 2025 | 3 articles | Viewed by 4174 | Submission Open
Keywords: granulation; drug formulation; tableting; process modelling; process optimization; scale-up
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
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