Multifunctional Drug Delivery Systems
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".
Deadline for manuscript submissions: 20 February 2026 | Viewed by 38
Special Issue Editor
Interests: oral drug delivery; oral bioavailability; nanotechnology; protein and peptide drugs
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Multifunctional drug delivery systems (MDDSs) represent a cutting-edge approach in modern therapeutics, designed to enhance the precision, efficacy, and safety of drug administration. These advanced systems integrate multiple functionalities, such as targeted delivery, controlled release, utilizing biomaterials to form carrier systems with natural immune-modulating effects, and stimuli-responsive behavior into a single platform, overcoming the limitations of conventional drug delivery methods. Leveraging nanotechnology, functional biomaterials, and smart polymers (e.g., pH-sensitive hydrogels and temperature-responsive polymers) ensures drug release at disease sites. MDDSs can improve drug bioavailability, reduce systemic toxicity, and enable the real-time monitoring of therapeutic responses.
Such innovations hold immense potential in treating complex diseases like cancer, neurological disorders, and chronic infections. Next-generation MDDSs may integrate AI-driven design, bioresponsive nanomaterials, and real-time immune monitoring for personalized therapy. Challenges include optimizing biocompatibility, scalability, and precise immune cell targeting. As research progresses, MDDSs are expected to revolutionize personalized medicine by offering tailored therapeutic solutions with improved patient outcomes.
Dr. Guanyu Chen
Guest Editor
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Keywords
- multifunctional delivery systems
- nanoparticles
- targeting delivery
- immune-modulating delivery systems
- nanoparticle conjugation
- sustained drug release
- smart polymers
- polysaccharide-based carriers
- smart nanocarrier systems
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