Special Issues

Pharmaceutics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Drug Product Performance: Bioavailability, Relative Bioavailability and Bioequivalence, 3rd Edition
edited by
submission deadline 10 Mar 2027 | 1 articles | Viewed by 1132 | Submission Open
Keywords: bioavailability; relative bioavailability; bioequivalence; biowaivers; statistical issues; regulatory issues; in vitro–in vivo correlations; physiologically based biopharmaceutical models; physiologically based pharmacokinetic models; qualification of models; population pharmacokinetic models; biopharmaceutical classification system; in vitro dissolution; dissolution metrics; predictive dissolution; clinical trial simulations; clinical trial optimization; healthy subjects in BA/BE trials; patients in BA/BE trials; pharmacokinetic parameters for BA/BE assessment; narrow therapeutic index drugs; highly variable drug products; immediate-release formulations; modified-release formulations; multiphasic drug products; extravascular routes of administration
(This special issue belongs to the Section Biopharmaceutics)
Pharmaceutical Innovations in Micro- and Nanotechnology for Topical and Transdermal Delivery of Synthetic and Biotechnological Molecules, and Herbal Extracts
edited by , Alejandra Rojas-Molina and
submission deadline 10 Mar 2027 | 1 articles | Viewed by 859 | Submission Open
Keywords: micro- and nanostructured drug delivery systems; topical and transdermal administration; solid lipid nanoparticles (SLNs); self-micro/nano-emulsifying drug delivery systems (SMEDDSs/SNEDDSs); bio-metal–organic frameworks (Bio-MOFs); liquid crystalline systems; liposomes and invasomes; polymeric nanostructures; skin penetration and retention; controlled release and formulation strategies
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advances in Lipid, Polymeric, and Albumin-Based Drug Delivery Systems
edited by and
submission deadline 10 Mar 2027 | Viewed by 495 | Submission Open
Keywords: nanoparticle; albumin nanoparticle; human serum albumin; polymeric nanoparticle; polymeric micelle; PLGA nanoparticle; lipid nanoparticle; liposome; nanomedicine
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Bridging Modulation and Delivery: Pharmaceutical Innovations Targeting Ion Channels and Transporters in Disease submission deadline 10 Mar 2027 | Viewed by 18 | Submission Open
Keywords: ion channels; membrane transporters; targeted drug delivery; ion channel modulators; precision pharmacotherapy
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Pharmaceutical Applications and Therapeutic Mechanisms of Substances from Plant Origin submission deadline 15 Mar 2027 | 8 articles | Viewed by 12062 | Submission Open
Keywords: natural substances; phytotherapy; phytochemistry; chromatography; pharmacokinetics; pharmacodynamics; drug delivery
(This special issue belongs to the Section Drug Targeting and Design)
Inhaled Advances: Emerging Trends in Pulmonary Drug Delivery submission deadline 20 Mar 2027 | 4 articles | Viewed by 9026 | Submission Open
Keywords: pulmonary drug delivery; microparticles; nanomedicines; infectious diseases; lung targeting
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Recent Advances in Gastrointestinal Disease: Insights into Drug Delivery and Cellular and Molecular Mechanisms for Therapy submission deadline 20 Mar 2027 | 2 articles | Viewed by 4305 | Submission Open
Keywords: gastrointestinal disease; drug delivery; molecular therapy; biological therapy; target therapy; molecular target; biomarkers; GI epithelial cells
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Carbon-Based Nanomaterials for Pharmaceutical Applications
edited by and Ivana Borišev
submission deadline 20 Mar 2027 | 3 articles | Viewed by 3902 | Submission Open
Keywords: carbon-based nanomaterials; drug delivery; fullerenes; graphene; carbon nanotubes; nanodiamonds; carbon dots; biocompatibility; pharmaceutical applications
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advancing HIV Prevention and Treatment: Pharmacokinetics, Pharmacodynamics, Toxicokinetics, Formulation and Delivery of Antiretroviral Drugs
edited by Julie B. Dumond
submission deadline 20 Mar 2027 | 3 articles | Viewed by 2355 | Submission Open
Keywords: long-acting injectable antiretrovirals; PK/PD modeling of antiretrovirals; predictions of HIV PrEP effectiveness; antiretroviral toxicokinetics; novel drug delivery systems; novel dosing strategies; HIV treatment or prevention therapeutics in development; clinical pharmacokinetic studies in key populations; HIV drug delivery innovations; mannose receptor-targeted delivery
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Design, Development and Biomedical Applications of Hyaluronic Acid-Based Drug and Gene Delivery Systems
edited by Cristina Casadidio and Alice Spadea
submission deadline 20 Mar 2027 | 1 articles | Viewed by 1539 | Submission Open
Keywords: hyaluronic acid; targeted drug delivery; gene delivery; CD44; nucleic acid delivery; HA conjugates; nanoparticles personalized medicine
(This special issue belongs to the Section Gene and Cell Therapy)
Ocular Drug Delivery: Innovative Nanocarriers for Sustained Therapeutic Efficacy
edited by Subbu S. Venkatraman
submission deadline 20 Mar 2027 | Viewed by 40 | Submission Open
Keywords: sustained efficacy of action; gene silencing; mRNA delivery; patient compliance; nanotoxicity
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Nanotechnology-Driven Drug Repurposing: A Novel Strategy for Targeted Drug Delivery and Pharmacokinetic Enhancement submission deadline 25 Mar 2027 | 4 articles | Viewed by 7238 | Submission Open
Keywords: nanotechnology; drug repurposing; targeted drug delivery; pharmacokinetics; nanocarriers
(This special issue belongs to the Section Drug Delivery and Controlled Release)
New Therapeutic Approaches for the Application of Natural Products in Skin Diseases submission deadline 25 Mar 2027 | 4 articles | Viewed by 3325 | Submission Open
(This special issue belongs to the Section Biopharmaceutics)
Solid Dispersions for Oral Delivery: Materials, Technologies, Characterization, and Translation
edited by , Andreea Loredana Vonica-Tincu and
submission deadline 25 Mar 2027 | 1 articles | Viewed by 1720 | Submission Open
Keywords: solid dispersions; amorphous solid dispersions; supersaturating drug delivery systems; poorly soluble drugs; BCS class II and IV drugs; solubility enhancement; dissolution enhancement; oral bioavailability; oral absorption; drug–polymer miscibility; precipitation inhibition; polymer carriers; hot-melt extrusion; spray drying; electrospinning; freeze-drying; solid-state characterization; physical stability; biorelevant dissolution; IVIVC; pharmacokinetics; quality by design; scale-up; regulatory science
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Recent Advances in Physiologically Based Biopharmaceutics Modeling
edited by Atsushi Kambayashi
submission deadline 31 Mar 2027 | 1 articles | Viewed by 2128 | Submission Open
Keywords: oral drug absorption; bioavailability; bioequivalence; modeling and simulation; physiologically based biopharmaceutics modeling
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Emerging Stimuli-Responsive Nanoparticles for Bioactive Delivery
edited by and Sangeun Lee
submission deadline 31 Mar 2027 | 2 articles | Viewed by 2112 | Submission Open
Keywords: disease microenvironment; smart nanoparticles; biofunctional nanomedicine
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Novel Applications of Modern Excipients in Advanced Pharmaceutical Products, 2nd Edition submission deadline 31 Mar 2027 | 2 articles | Viewed by 2061 | Submission Open
Keywords: pharmaceutical excipients; inactive ingredients; preformulation/formulation; drug-excipient compatibility; particle size, shape and morphology; oral solid dosage forms; solubility/dissolution rate; chemical and physical stability; manufacturing process
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Sustainable Nanotechnologies Derived from Renewable Resources for Advanced Drug Design, Delivery and Therapy submission deadline 31 Mar 2027 | 1 articles | Viewed by 1372 | Submission Open
Keywords: sustainable nanotechnology; renewable resources; green synthesis; drug delivery systems; natural products; nanomedicine; photodynamic therapy; advanced therapeutics
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advances in Pharmacogenomics and Personalized Therapy
edited by
submission deadline 31 Mar 2027 | 2 articles | Viewed by 1336 | Submission Open
Keywords: pharmacogenomics; pharmacogenetics; personalized therapy
(This special issue belongs to the Section Clinical Pharmaceutics)
Recent Advances in Controlled Release and Targeted Drug Delivery Formulations for Improved Efficacy and Reduced Side Effects
edited by
submission deadline 31 Mar 2027 | 1 articles | Viewed by 1200 | Submission Open
Keywords: pharmaceutical formulation; controlled release; drug targeting; improved efficacy; local drug delivery; reduced side effect
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Nasal and Inhalable Drug Delivery Systems
edited by
submission deadline 31 Mar 2027 | 1 articles | Viewed by 531 | Submission Open
Keywords: nose-to-brain drug delivery; pulmonary drug delivery; formulations and excipients for nasal/pulmonary delivery; inhalation devices; fundamentals of aerosol generation and deposition; advanced nanocarriers for nasal/pulmonary delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Metal Nanoparticles for Controlled Release of Drugs and Bioactive Compounds submission deadline 31 Mar 2027 | Viewed by 454 | Submission Open
Keywords: gold nanoparticles; metal nanoparticles; drug delivery systems; controlled release; pharmacokinetics; Surface-Enhanced Raman Scattering (SERS); green synthesis; preclinical studies; release kinetics; theragnostics; gene delivery
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advanced Characterization and Bioequivalence Strategies for Complex Long-Acting Injectable Systems
edited by
submission deadline 31 Mar 2027 | Viewed by 414 | Submission Open
Keywords: long-acting injectables; bioequivalence; prodrug conjugation; PLGA microspheres; in situ gels; nanocrystal suspensions; sustained release; injectable formulations
(This special issue belongs to the Section Biopharmaceutics)
Innovative Strategies for Precision Intervention in Brain Diseases
edited by Julia Y. Ljubimova and
submission deadline 31 Mar 2027 | Viewed by 316 | Submission Open
Keywords: blood–brain barrier; nanomedicine drug delivery; neurodegenerative diseases; brain tumors; precision medicine; CNS disorders; multifunctional nanomaterials; personalized therapy
(This special issue belongs to the Section Drug Targeting and Design)
Precision Nanomedicine for Immunotherapy submission deadline 31 Mar 2027 | Viewed by 202 | Submission Open
Keywords: nanomedicine; immune modulation; precision medicine; targeted drug delivery; immunotherapy; angiogenesis; biomaterials; regenerative medicine; inflammation and fibrosis; cancer therapy
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Nanogels: An Innovative Approach to Personalized Medicine submission deadline 31 Mar 2027 | Viewed by 190 | Submission Open
Keywords: nanogels; drug delivery; targeting; personalized medicine
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Recent Advances in Nanomedicine Using Organoids, Microfluidics, and Organ-on-a-Chip Technologies
edited by
submission deadline 31 Mar 2027 | Viewed by 62 | Submission Open
Keywords: nanomedicine; nanoparticles; drug delivery; therapeutic evaluation; diagnostics; theranostics; organoids; spheroids; microfluidics; organ-on-a-chip; tumor-on-a-chip; brain-on-a-chip; precision medicine; cancer; neurodegenerative diseases; infectious diseases; drug screening; translational medicine
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advances in Antiparasitic Agents, 2nd Edition
edited by Juan José García-Rodríguez
submission deadline 31 Mar 2027 | Viewed by 57 | Submission Open
Keywords: parasites; parasitic diseases; drug combinations; antiparasitic activity; pharmacokinetics; drug resistance; mechanism of action; formulations; drug synthesis and discovery
(This special issue belongs to the Section Drug Targeting and Design)
Advances in Non-Invasive Drug Delivery Systems submission deadline 31 Mar 2027 | Viewed by 47 | Submission Open
Keywords: non-invasive drug delivery; drug delivery systems; nanomedicine; nanocarriers; controlled drug release; biological barriers
(This special issue belongs to the Section Drug Delivery and Controlled Release)
New Insights into Radiopharmaceuticals for Cancer Therapy and Diagnosis
edited by , Valery I. Radchenko and Aryel Heitor Ferreira
submission deadline 31 Mar 2027 | Viewed by 43 | Submission Open
Keywords: radiopharmaceuticals; precision oncology; cancer imaging; targeted radionuclide therapy; theranostics; molecular imaging; radiochemistry; PET/SPECT; nuclear medicine
(This special issue belongs to the Section Drug Targeting and Design)
Small Molecules for Age-Related Diseases submission deadline 31 Mar 2027 | Viewed by 38 | Submission Open
Keywords: age-related chronic diseases; small molecules; cellular and molecular pharmacology
(This special issue belongs to the Section Drug Targeting and Design)
Drug Design, Discovery and Delivery in Targeted Therapy
edited by , and Slavica Oljacic
submission deadline 31 Mar 2027 | Viewed by 24 | Submission Open
Keywords: drug design; drug discovery; drug delivery; chemoinformatics; molecular modeling; drug repurposing; multitarget ligands; targeted therapy; physicochemical properties; biological evaluation; ADMET profiling; delivery systems
(This special issue belongs to the Section Drug Targeting and Design)
Emerging Drugs and Formulations for Pain Treatment, 2nd Edition
edited by Héctor Isaac Rocha-González and
submission deadline 31 Mar 2027 | Viewed by 24 | Submission Open
Keywords: chronic pain; inflammatory pain; nociplastic pain; neuropathic pain; oncology pain; emerging drugs; analgesia; pharmacological therapies; pain relief
(This special issue belongs to the Section Clinical Pharmaceutics)
Therapeutic Peptides: From Design to Clinical Applications
edited by
submission deadline 31 Mar 2027 | Submission Open
Keywords: peptides; peptide discovery; peptide design; drug delivery; peptide-drug conjugates; clinical translation; regenerative medicine; antimicrobial peptides; computational peptide design
(This special issue belongs to the Section Biologics and Biosimilars)
Nano-Drug Delivery Systems: Tackling Cancer Metabolism and Drug Resistance
edited by
submission deadline 10 Apr 2027 | Viewed by 725 | Submission Open
Keywords: nano-drug delivery systems; tumor microenvironment; cancer metabolism; metabolic reprogramming; drug resistance; targeted therapy; combination therapy
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances in Vaccine Delivery and Vaccine Administration submission deadline 20 Apr 2027 | 1 articles | Viewed by 3688 | Submission Open
Keywords: vaccine delivery; vaccination; vaccine immunity; humoral immune response; cell-mediated immunity; infectious diseases; vaccine administration; novel routes of vaccination; nanoparticles
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Recent Advances on Molecular Modeling in Pharmaceutics submission deadline 20 Apr 2027 | 1 articles | Viewed by 2480 | Submission Open
Keywords: DFT; quantum mechanics; molecular mechanics; quantum chemistry; molecular dynamics; adsorption simulations; molecular modeling; pharmacokinetics; biopharmaceutics
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Natural Products in Photodynamic Therapy, 2nd Edition
edited by and Gustavo Braga
submission deadline 20 Apr 2027 | Viewed by 281 | Submission Open
Keywords: photodynamic therapy; photosensitizer; natural product; bioactive compounds; combination therapy
(This special issue belongs to the Section Drug Targeting and Design)
Ocular Drug Delivery Systems and Formulations submission deadline 27 Apr 2027 | 4 articles | Viewed by 5038 | Submission Open
Keywords: ocular drug delivery; ophthalmic formulations; ophthalmic drug bioavailability; ophthalmic hydrogels; ophthalmic pharmaceutical nanotechnology; ocular therapies
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Biomaterials for Skin Drug Delivery
edited by
submission deadline 28 Apr 2027 | 3 articles | Viewed by 4228 | Submission Open
Keywords: skin drug delivery; transdermal delivery; topical delivery; skin permeation; biomaterials; hydrogels; microneedles; nanocarriers; bioresponsive materials
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Recent Advances in Antibody–Drug Conjugates for Cancer Therapy
edited by Claudia Parisi
submission deadline 30 Apr 2027 | 1 articles | Viewed by 717 | Submission Open
Keywords: ADC; solid tumours; target selection; payload; resistance; tumour biology
(This special issue belongs to the Section Biologics and Biosimilars)
Amorphous Formulations and Solid-State Strategies to Improve Oral Drug Performance: Bridging Enabling Technologies, Biopharmaceutics, and Patient-Centric Product Design
edited by Réka Angi and
submission deadline 30 Apr 2027 | Viewed by 301 | Submission Open
Keywords: amorphous solid dispersion; solid-state characterization; dissolution; solubility; physical stability; polymer excipients; spray drying; hot-melt extrusion; patient-centric formulation; geriatric/pediatric formulation; medication adherence
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Nanomedicines for Immunotherapy
edited by Mengyu Chang
submission deadline 30 Apr 2027 | Viewed by 260 | Submission Open
Keywords: nanomedicine; biomimetic nanoparticles; immunotherapy; cancer immunology; drug delivery systems; tumor microenvironment
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Trends in Controlled and Targeted Drug Delivery for Central Nervous System Disorders: From Nanocarriers to Implants submission deadline 30 Apr 2027 | Viewed by 70 | Submission Open
Keywords: drug formulation; drug delivery systems; controlled and sustained release; brain-targeted drug delivery; blood–brain barrier; central nervous system disorders; neurodegenerative diseases; brain tumors; Parkinson’s disease; Alzheimer’s disease; schizophrenia; depression
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Drug–Drug Interactions—New Perspectives submission deadline 1 May 2027 | 3 articles | Viewed by 5029 | Submission Open
Keywords: safety of therapy; cytochrome P450; pharmacokinetics; contraindication; machine learning; metabolism
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Metal Complexes as Antimicrobial Agents: Pharmacokinetics and Drug Development Implications submission deadline 15 May 2027 | 1 articles | Viewed by 1623 | Submission Open
Keywords: metal complexes; antimicrobial agents; drug development; therapeutic agents; pharmacokinetics
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Unlocking the Potential of Extracellular Vesicles as Novel Drug Delivery Platform–Latest Achievements
edited by
submission deadline 30 May 2027 | Viewed by 78 | Submission Open
Keywords: extracellular vesicles; exosomes; drug delivery systems; hybrid nanoparticles; biomaterials; hydrogels; targeted therapy; cancer therapy
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Natural Products and Their Bioinspired Nanodelivery Systems for Immune Microenvironment Modulation
edited by
submission deadline 31 May 2027 | Viewed by 104 | Submission Open
Keywords: nanodelivery systems; formulation design; pharmacokinetics; pharmacodynamics; immunomodulation; natural products
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Rational Design of Nanosystems for Controlled and Targeted Drug Release submission deadline 31 May 2027 | Viewed by 23 | Submission Open
Keywords: nanomedicines; rational design; artificial intelligence; design of experiments; mathematical modeling; targeted drug delivery; polymeric nanoparticles; lipid-based nanocarriers; bioengineering
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Bridging the Gut–Brain Axis: Advanced Drug Delivery, Microbiome Modulation, and Translational Therapeutics submission deadline 30 Jun 2027 | Viewed by 99 | Submission Open
Keywords: gut–brain axis; microbiome–gut–brain interactions; drug delivery systems; nanomedicine
(This special issue belongs to the Section Drug Delivery and Controlled Release)
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