Special Issues

Pharmaceutics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Optimizing Drug Therapy Through Pharmacokinetics and Therapeutic Drug Monitoring
edited by Kazuro Ikawa and
submission deadline 30 Sep 2026 | Viewed by 358 | Submission Open
Keywords: dosing optimization; therapeutic drug monitoring; pharmacokinetics; pharmacodynamics; modeling and simulation; special population
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Precision Local Drug Delivery: From Formulation Design to Local Bioavailability Assessment
edited by
submission deadline 30 Sep 2026 | Viewed by 340 | Submission Open
Keywords: locally acting dosage form; drug delivery; local delivery; semi-solid formulations; mucoadhesion; permeation; controlled release; bioequivalence assessment
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Pharmacokinetic Perspectives on Drug Interactions in Therapy submission deadline 30 Sep 2026 | Viewed by 284 | Submission Open
Keywords: drug–drug interactions (DDIs); drug metabolism; cytochrome P450; transport proteins; computational modeling; physiologically based pharmacokinetic (PBPK) model
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Advancing Drug Delivery Systems and Pharmaceutical Formulations submission deadline 30 Sep 2026 | Viewed by 280 | Submission Open
Keywords: drug delivery systems; pharmaceutical formulations; active pharmaceutical ingredients; bioavailability; nanoscale systems; lipid-based carriers; polymer-based carriers; amorphous formulations; solid-state formulations; hybrid materials; controlled release; stimuli-responsive delivery; site-specific delivery; physicochemical characterization; biopharmaceutical evaluation; in vitro-in vivo correlation; translational research; quality-by-design; scalable manufacturing; therapeutic efficacy
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Emerging Strategies in Drug Development and Clinical Care in the Era of Personalized and Precision Medicine, 3rd Edition submission deadline 30 Sep 2026 | Viewed by 273 | Submission Open
Keywords: drug development; therapeutic strategies; preclinical and clinical drug research; drug design; drug–drug interactions; clinical care; toxicological studies; disease risk, disease prognosis and response to therapy; biomarkers identification and application; biochemistry of drug uptake, action, and metabolism; drug target discovery; individualized therapy; pharmacogenomics; novel therapeutics; non-drug-related health interferences; nutritional interventions; chronobiology; medicinal chemistry; phytochemicals; biologics; personalized medicine; precision medicine
(This special issue belongs to the Section Clinical Pharmaceutics)
Next-Generation Cholinesterase Inhibitors for Alzheimer's Disease: New Targets and Strategies
edited by Josélia A Lima and
submission deadline 30 Sep 2026 | Viewed by 264 | Submission Open
Keywords: Alzheimer’s disease; acetylcholinesterase; butyrylcholinesterase; multi-target ligands; metal quelation; neuroinflammation; PAS; amyloid-beta; tau; MAO-B; pharmacokinetic/pharmacodynamic (PK/PD)
(This special issue belongs to the Section Drug Targeting and Design)
Novel Approaches for Insulin Delivery
edited by Charles W. Putnam and Klearchos K. Papas
submission deadline 30 Sep 2026 | Viewed by 261 | Submission Open
Keywords: insulin; insulin pharmacokinetics; beta cells; stem cells; genetically modified; devices; routes of administration; delivery; novel; cell therapy
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Polymer-Based Nanotechnology Delivery Systems for Nucleic Acids submission deadline 30 Sep 2026 | Viewed by 254 | Submission Open
Keywords: polymer-based nanoparticles; nucleic acid delivery systems; therapeutic nucleic acids (TNAs); cancers; vaccines; cardiovascular diseases; polymeric micelles, dendrimers, polyplexes; mRNA and gene editing delivery approaches; translational and preclinical studies
(This special issue belongs to the Section Gene and Cell Therapy)
Where Are We Now and Where Is Cell Therapy Headed? (2nd Edition) submission deadline 15 Oct 2026 | 2 articles | Viewed by 3960 | Submission Open
Keywords: stem cells; mesenchymal stromal cells; cell therapy; CAR-T; CAR-NK; cancer; gene therapy; organoids and organ on a chip; extracellular vesicles; secretome
(This special issue belongs to the Section Gene and Cell Therapy)
Vesicle-Based Drug Delivery Systems
edited by and Paula Messina
submission deadline 20 Oct 2026 | 3 articles | Viewed by 15132 | Submission Open
Keywords: liposomes; exosomes; extracellular vesicles; niosomes; polymersomes; active and passive targeting; pharmacokinetics; isolation/synthesis; functionalization; modified release
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Targeted Therapies and Drug Delivery for Neurodegenerative Diseases
edited by and Chiara Lucchi
submission deadline 20 Oct 2026 | 5 articles | Viewed by 14559 | Submission Open
Keywords: targeted drug delivery; blood–brain barrier; neurodegenerative disease treatment; precision medicine; neuroscience
(This special issue belongs to the Section Drug Targeting and Design)
Application of Marine-Derived Polymers in Drug Dosage Forms submission deadline 20 Oct 2026 | 3 articles | Viewed by 6639 | Submission Open
Keywords: pharmaceutical formulations; controlled drug release; biological activity of drug fromulations; marine-derived polymers; alginates; chitosan; fucoidan
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Recent Advances in Antimicrobial Drug Delivery
edited by and
submission deadline 20 Oct 2026 | 3 articles | Viewed by 4547 | Submission Open
Keywords: antimicrobial drug delivery; nanoparticles; controlled release; targeted therapy; antimicrobial resistance; nanomedicine; smart drug delivery systems; surface modification; biofilm treatment; advanced drug delivery strategies
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Biopolymer Nanoparticles for Targeted Therapy in Cardiovascular Diseases
edited by Lino Sánchez-Segura and Silvio Zaina
submission deadline 20 Oct 2026 | 1 articles | Viewed by 2133 | Submission Open
Keywords: nanoparticles; biopolymers; drug-load; drug delivery; target; cardiovascular disease; therapy
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advanced Nanotechnology-Based Strategies for Ocular Diseases Treatment
edited by and Andreia Martins Rosa
submission deadline 20 Oct 2026 | Viewed by 220 | Submission Open
Keywords: biomaterials; nanoparticles; gene therapy; regenerative medicine; theranostics; natural products
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Cutting-Edge Drug Delivery and Nanomedicine: Innovations in Hybrid Systems, Theranostics and Targeted Therapies submission deadline 25 Oct 2026 | 6 articles | Viewed by 17202 | Submission Open
Keywords: drug delivery; nanomedicine; hybrid nanosystems; targeted therapies; theragnostic; drug repurposing; PDT; PTT
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Population Pharmacokinetics and Its Clinical Applications, 2nd Edition submission deadline 25 Oct 2026 | 1 articles | Viewed by 670 | Submission Open
Keywords: model-informed precision dosing (MIPD); therapeutic drug monitoring (TDM); dosing adjustments; special populations; nonlinear mixed-effects modeling (NONMEM); PK/PD models
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Solid Dispersions for Drug Delivery: Development, Preparation and In Vitro/In Vivo Characterization, 2nd Edition submission deadline 25 Oct 2026 | Viewed by 188 | Submission Open
Keywords: solid dispersion; poorly soluble drugs; stability; dissolution properties; molecular interaction; polymers
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Advances in Physiologically Based Pharmacokinetic (PBPK) Modeling and Applications
edited by
submission deadline 29 Oct 2026 | 6 articles | Viewed by 17933 | Submission Open
Keywords: physiologically based pharmacokinetic (PBPK) modeling; IVIVE; pharmacokinetics; ADME; modeling and simulation; PK/PD; biopharmaceutics; quantitative systems pharmacology
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Topical Drug Delivery for Skin Diseases
edited by Rudolf E. Schopf
submission deadline 30 Oct 2026 | Viewed by 501 | Submission Open
Keywords: topical drug delivery; skin diseases; psoriasis; eczema; nanotechnology; liposomes; ethosomes; microneedles; hydrogels; controlled release; dermal penetration
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Recent Advances in Non-Viral Vectors for Gene Therapy and Gene Delivery
edited by
submission deadline 31 Oct 2026 | 2 articles | Viewed by 8814 | Submission Open
Keywords: non-viral gene delivery; lipid nanoparticle; polymeric carrier; endosomal escape; genome editing delivery
(This special issue belongs to the Section Gene and Cell Therapy)
Advances in Nanotechnology-Based Drug Delivery Systems, 2nd Edition
edited by
submission deadline 31 Oct 2026 | 5 articles | Viewed by 8432 | Submission Open
Keywords: biomaterials; nanomedicine; nanotechnology; formulations; green production technologies; biological macromolecule nanoencapsulation
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Development and Optimization of Buccal Films Formulations
edited by and Krisztián Pamlényi
submission deadline 31 Oct 2026 | 3 articles | Viewed by 8312 | Submission Open
Keywords: buccal drug delivery; mucoadhesive; polymer films; buccal tablets; solid dosage forms; controlled drug release; fast dissolving formulations; permeability enhancement; pediatric formulations; geriatric formulations
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Advances in Solid and Semi-Solid Dosage Form Design for Enhanced Biopharmaceutical Performance submission deadline 31 Oct 2026 | 2 articles | Viewed by 7761 | Submission Open
Keywords: solid dosage forms (tablets, capsules, pellets); novel formulation strategies; bioavailability enhancement; amorphous solid dispersions; lipid-based formulations; pharmaceutical cocrystals; excipient functionality and drug release; 3D printing in pharmaceuticals; hot melt extrusion (HME); spray drying in drug formulation; co-processing techniques; controlled and sustained drug release; targeted drug delivery systems; in vitro/in vivo correlation (IVIVC); quality-by-design (QbD) in pharmaceutics
(This special issue belongs to the Section Biopharmaceutics)
Nanoparticle-Based Drug Formulation for Enhancing Nose-to-Brain Delivery
edited by and Richard Nii Lante Lamptey
submission deadline 31 Oct 2026 | 3 articles | Viewed by 7116 | Submission Open
Keywords: nanoparticles; nose-to-brain drug delivery; blood–brain barrier (BBB); central nervous system (CNS); neurodegenerative diseases; targeted therapeutics; non-invasive delivery; intranasal administration
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Ocular Drug Delivery System submission deadline 31 Oct 2026 | 4 articles | Viewed by 6846 | Submission Open
Keywords: drug delivery; nanoparticles; controlled release; hydrogels; liposomes; microneedle arrays
(This special issue belongs to the Section Drug Delivery and Controlled Release)
From Nature to Pharmacy: Advances in Bio-Based Pharmaceutical Formulations submission deadline 31 Oct 2026 | 4 articles | Viewed by 6640 | Submission Open
Keywords: natural products; drug delivery systems; bioactive ingredients; nanotechnology; bioavailability; pharmaceutical formulations; plant-derived compounds; biocompatible carriers
(This special issue belongs to the Section Biopharmaceutics)
Functionalized Polymers for Anticancer Applications
edited by Alejandro Ramirez-Jimenez, and
submission deadline 31 Oct 2026 | 1 articles | Viewed by 4610 | Submission Open
Keywords: photodynamic therapy; photothermal therapy; sonodynamic therapy; immunotherapy; smart polymeric nanocarriers; specific drug delivery; functionalized polymers; anticancer drug delivery; metallodrugs; theragnostic
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Optimizing Aerosol Therapy: Strategies for Pulmonary Drug Delivery submission deadline 31 Oct 2026 | 4 articles | Viewed by 4600 | Submission Open
Keywords: pulmonary drug delivery; aerosol therapy; inhalation drug delivery; particle engineering; inhaled biologics and vaccines; aerosol characterization; in vitro-in vivo correlation (IVIVC); inhaler devices; lung deposition; clinical translation
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advanced Nano-Based Drug Delivery Systems for Infectious Diseases
edited by Claudio J. Salomon and Maria Celina Lamas
submission deadline 31 Oct 2026 | 2 articles | Viewed by 4502 | Submission Open
Keywords: nanomedicines; infectious disease; microorganisms; therapeutic treatments; drug delivery systems
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advancing Precision Diagnosis and Therapy with Targeted Radiopharmaceuticals in Cancer and Systemic Diseases submission deadline 31 Oct 2026 | 3 articles | Viewed by 3706 | Submission Open
Keywords: radiopharmaceuticals; diagnostics imaging; theranostics; radionuclides; radioligand therapy; cancer; neurological disorders; dosimetry; preclinical studies; clinical studies; clinical translation
(This special issue belongs to the Section Drug Targeting and Design)
New Era in Antimicrobial Strategies
edited by
submission deadline 31 Oct 2026 | 2 articles | Viewed by 3579 | Submission Open
Keywords: artificial intelligence; phage therapy; microbiome; host-directed therapy; nanoparticles; precision medicine; antimicrobial agents; drug repositioning
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Engineering of Advanced Nanocarriers and Extracellular Vesicle Systems for Precision Drug Delivery
edited by , Eugenia Romano and
submission deadline 31 Oct 2026 | 1 articles | Viewed by 3328 | Submission Open
Keywords: nanomedicine; extracellular vesicles; hybrid nanocarriers engineered nanoparticles; surface functionalization; biomimicry; drug delivery; clinical translation
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Targeted Drug Delivery Strategies for Infectious Diseases
edited by Danielle Lazarin Bidóia, Daniele Stéfanie Sara Lopes Lera-Nonose and
submission deadline 31 Oct 2026 | 2 articles | Viewed by 3090 | Submission Open
Keywords: infectious disease; treatment; delivery system; biomaterial; targeted drug therapy; liposome; dendrimer; nanotube; nanotechnology; formulation; polymer; antifungal; antimicrobial; antiparasitic; antibiotic; bacterial infection; adjuvant; antiviral; biofilm-related infection; bacteria; antiparasitic
(This special issue belongs to the Section Drug Targeting and Design)
Recent Advances in Drug Delivery Through Microneedle-Based Systems submission deadline 31 Oct 2026 | 1 articles | Viewed by 3026 | Submission Open
Keywords: microneedle-based systems; microneedles; micro array patches; skin delivery; transdermal delivery; vaccination
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances in Natural Anticancer Formulation submission deadline 31 Oct 2026 | 2 articles | Viewed by 2473 | Submission Open
Keywords: cancer treatment; phytocompounds; drug formulations; natural-based therapies; in vitro and ex vivo toxicity evaluation; in vivo drug sensitivity; in silico models; pharmacokinetics/pharmacodynamics; innovations
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Drug Delivery Strategies and Novel Approaches for Cancer Treatment submission deadline 31 Oct 2026 | 2 articles | Viewed by 2458 | Submission Open
Keywords: nanocarriers; drug delivery; cancer therapy; targeted delivery; drug repurposing; controlled release; nanotechnology; anticancer agents
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advanced Drug Delivery Systems for Enhanced Transdermal and Dermal Delivery
edited by and Jinbing Xie
submission deadline 31 Oct 2026 | 2 articles | Viewed by 1697 | Submission Open
Keywords: cutaneous drug delivery; transdermal delivery; skin penetration; advanced delivery systems; micro- and nanocarriers; microneedles; dermatological applications
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Innovative Oral and Topical Drug Delivery Systems: Formulation Design, Optimization and Quality Control
edited by , Alvaro Jimenez-Kairuz and José Bermudez
submission deadline 31 Oct 2026 | 1 articles | Viewed by 1634 | Submission Open
Keywords: oral formulations; topical formulations; lipid-based delivery systems; polymeric delivery systems; mucoadhesive platforms; micro/nanoparticulate carriers; stimuli-responsive delivery systems; polymeric hydrogels; vesicles; solid dispersions; co-crystals; complexes; in situ forming systems; pharmaceutical formulations; bioavailability enhancement; solubility and permeability improvement; 3D printing in pharmaceutics; Quality by Design (QbD); hot-melt extrusion; pharmaceutical quality control
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances in Nanoemulsion for Drug Delivery
edited by Feng Zhang and
submission deadline 31 Oct 2026 | 1 articles | Viewed by 1546 | Submission Open
Keywords: nanoemulsion formulations and stability; topical delivery; poorly soluble drugs; targeted drug and biologics delivery; theranostic platform and imaging; vaccines and adjuvants; cancer; infectious diseases; pulmonary diseases
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Pathophysiological Influences on Pharmacokinetics and Pharmacodynamics, 2nd Edition
edited by Geraldo Duarte, Fernanda de Lima Moreira and Jhohann Richard de Lima Benzi
submission deadline 31 Oct 2026 | 1 articles | Viewed by 1200 | Submission Open
Keywords: drug–disease interactions; pharmacokinetics; pharmacodynamics; pharmacotherapy
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Metal–Organic Frameworks for Pharmaceutical Applications
edited by Arvin Eskandari
submission deadline 31 Oct 2026 | 1 articles | Viewed by 1176 | Submission Open
Keywords: metal–organic frameworks (MOFs); drug delivery systems; controlled release; theranostics; biomedical imaging; biocompatibility and stability; MOF composites; hybrid MOF materials; oral and implantable delivery; artificial intelligence (AI) and machine learning (ML); translational pharmaceutics
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Polymeric Films as a Multipurpose Drug Delivery System: Application, Properties, Preparation and Evaluation submission deadline 31 Oct 2026 | 1 articles | Viewed by 1087 | Submission Open
Keywords: drug delivery system; polymers; polymeric films; physicochemical and texture characteristics; film production techniques; controlled and sustained release; adhesion; bioavailability; formulation; evaluation
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances in Antimicrobial Peptides for Biomedical Applications
edited by Na Yang
submission deadline 31 Oct 2026 | 1 articles | Viewed by 835 | Submission Open
Keywords: antimicrobial peptides (AMPs); drug delivery; peptide engineering; broad-spectrum activity; mechanism of action; nanoparticle encapsulation; structure–activity relationship; biocompatibility; translational research
(This special issue belongs to the Section Drug Targeting and Design)
Advanced Drug Nanocrystals
edited by Nadia Araci Bou-Chacra
submission deadline 31 Oct 2026 | Viewed by 572 | Submission Open
Keywords: preparation of drug nanocrystals: key factors affecting their stability; quality by design (QbD) approach, critical quality attributes (CQAs), and process insights for the production of drug nanocrystals; scaling up and down: industrial applications of drug nanocrystals; characterization methods for drug nanocrystals; applications of drug nanocrystals across various drug delivery routes and therapies; in vivo fate and cellular uptake of drug nanocrystals: exploring pharmacokinetics and pharmacodynamics
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Pharmaceutical Cocrystals: Design, Development, and Therapeutic Applications submission deadline 31 Oct 2026 | Viewed by 495 | Submission Open
Keywords: cocrystals; solubility; dissolution; controlled release; formulation; poorly water-soluble; bioavailability enhancement; supersaturation; solid dosage forms; drug-drug cocrystals; prediction of cocrystal formation; crystal structure–property relationships; in vitro-in vivo correlation
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Focused Ultrasound-Assisted Drug Delivery and Therapeutic Modulation
edited by Chanho Kong
submission deadline 31 Oct 2026 | Viewed by 380 | Submission Open
Keywords: focused ultrasound; blood–brain barrier; drug delivery; noninvasive therapy; neuromodulation; brain tumors; Alzheimer's disease; neurodegenerative disease; central nervous system; therapeutic modulation
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances in Oral Drug Delivery Systems
edited by Gioconda Millotti
submission deadline 31 Oct 2026 | Viewed by 372 | Submission Open
Keywords: oral drug delivery; oral formulation; nanotechnology; polymer-based carrier; lipid-based carrier
(This special issue belongs to the Section Drug Delivery and Controlled Release)
From Bench to Bedside: AAV, Lentivirus, Adenovirus, and Retrovirus in Gene Therapy
edited by and Driss Elhanafi
submission deadline 31 Oct 2026 | Viewed by 338 | Submission Open
Keywords: gene therapy; viral vectors; adeno-associated virus (AAV); lentiviral vectors; adenoviral vectors; retroviral vectors; vector design and engineering; clinical translation; gene delivery; bioprocess development
(This special issue belongs to the Section Gene and Cell Therapy)
Novel Micro/Nanomaterial-Based Drug Delivery Systems for Theranostic Applications, 2nd Edition submission deadline 31 Oct 2026 | Viewed by 299 | Submission Open
Keywords: nanotechnology; drug delivery systems; theranostics; micro/nanomaterials; personalized medicine; nanomedicine; cancer; diagnosis
(This special issue belongs to the Section Drug Delivery and Controlled Release)
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