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Pharmaceutics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Application of Nanomedicine in Metabolic and Chronic Diseases

edited by Mehrnaz Abbasi

submission deadline 30 Dec 2025 | 2 articles | Viewed by 5919 | Submission Open

Keywords: nanomedicine; metabolic diseases; chronic diseases; drug delivery; nanoscale materials; targeted therapy; controlled release

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Nanotechnology in Antibacterial Drug Delivery

edited by

Sharon Shui Yee Leung

submission deadline 30 Dec 2025 | 1 articles | Viewed by 1361 | Submission Open

Keywords: multidrug resistance; antibiotic resistance; multidrug-resistant bacteria; antibiotics; antibacterial therapies; nanotechnology; antibacterial drug delivery; nanoparticles; targeted delivery; controlled release

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

New Trends in the Controlled Release Systems of Medicinal Substances Used in the Treatment of Diseases of the Central Nervous System

edited by

Artur Turek

and

Zhenjia Wang

submission deadline 31 Dec 2025 | 5 articles | Viewed by 25478 | Submission Open

Keywords: drug delivery systems; brain-targeting drug delivery; central nervous system; schizophrenia; depression; Parkinson’ s disease; Alzheimer’ s disease; glioblastoma multiforme

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Novel Micro/Nanomaterials Based Drug Delivery Systems for Theranostic Applications

edited by

Pedro Fonte

Pedro Brandão

and

Sofia de Oliveira Dias Duarte

submission deadline 31 Dec 2025 | 6 articles | Viewed by 13315 | Submission Open

Keywords: nanotechnology; drug delivery systems; theranostics; micro/nanomaterials; personalized medicine; nanomedicine; cancer; diagnosis

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Dermal and Transdermal Drug Delivery Systems

edited by

Mara Madalina Mihai

and

Olguta Anca Orzan

submission deadline 31 Dec 2025 | 5 articles | Viewed by 10839 | Submission Open

Keywords: transdermal drug delivery; dermal drug delivery; nanotechnology; biopatch; nanocarriers; microneedles; skin penetration; electroporation; iontophoresis

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Cutting-Edge Drug Delivery and Nanomedicine: Innovations in Hybrid Systems, Theranostics and Targeted Therapies

edited by

Maria Natalia Calienni

and

Marcela Analia Moretton

submission deadline 31 Dec 2025 | 6 articles | Viewed by 7659 | Submission Open

Keywords: drug delivery; nanomedicine; hybrid nanosystems; targeted therapies; theragnostic; drug repurposing; PDT; PTT

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Development of New Nanotechnological Systems Loaded with Drugs for Infectious Disease Application

edited by

Gabriel Davi Marena

Marlus Chorilli

and Taís Maria Bauab

submission deadline 31 Dec 2025 | 5 articles | Viewed by 7520 | Submission Open

Keywords: nanosystems; controlled drug release; infectious diseases; microbial resistance; pathogenic microorganism; drug delivery systems; nanotechnology; nanotherapy

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Application Prospects of Hydrogels in Drug Delivery Systems

edited by

Fátima Raquel Maia

Rui L. Reis

and

Joaquim Miguel Oliveira

submission deadline 31 Dec 2025 | 2 articles | Viewed by 6328 | Submission Open

Keywords: hydrogels; osteochondral defects; drug-delivery systems; cell-laden hydrogels; nanoparticle-loaded hydrogels

(This special issue belongs to the Section Drug Targeting and Design)

Recent Advances in Inhibitors for Targeted Therapies

edited by Anke Wilhelm

submission deadline 31 Dec 2025 | 7 articles | Viewed by 5803 | Submission Open

Keywords: targeted therapy; emerging technologies; antiviral strategies; inhibitor development; molecular targets; precision medicine; drug R& D dynamics; pharmaceutics; drug resistance

(This special issue belongs to the Section Drug Targeting and Design)

Drug Delivery Systems for Ocular Diseases

edited by

Gonzalo Carracedo

and

Maria Vivero-Lopez

submission deadline 31 Dec 2025 | 6 articles | Viewed by 5706 | Submission Open

Keywords: ocular diseases; contact lens delivery; drug delivery systems; nanotechnology

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Stem Cell Therapy and Nanodelivery Systems for Tissue Engineering

edited by

Yoshie Arai

submission deadline 31 Dec 2025 | 1 articles | Viewed by 4919 | Submission Open

Keywords: biomaterials; multipotent stem cells; tissue regeneration; adult stem cells; induced pluripotent stem cells; cell engineering; tissue engineering; organoid

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Cell-Mediated Delivery Systems

edited by

Monia Taranta

and

Lisa Gherardini

submission deadline 31 Dec 2025 | 5 articles | Viewed by 3756 | Submission Open

Keywords: cell-targeted drug delivery; cell-mediated drug transport; targeted therapy; cellular uptake; nanocarriers for drug delivery

(This special issue belongs to the Section Gene and Cell Therapy)

The Development of Drug Delivery Systems and Pharmaceutical Formulations for the Treatment of Infectious Diseases

edited by José María Bermúdez and

Santiago Daniel Palma

submission deadline 31 Dec 2025 | 2 articles | Viewed by 3670 | Submission Open

Keywords: drug delivery systems; pharmaceutical formulations; nanoformulations; parasitic infections; controlled drug release

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Recent Advances in Physiologically Based Pharmacokinetics

edited by Li Liu

submission deadline 31 Dec 2025 | 2 articles | Viewed by 3133 | Submission Open

Keywords: physiologically based pharmacokinetic (PBPK) model; pharmacometrics; drug– drug interaction; pharmacokinetics and pharmacodynamics

(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)

Exploring the Versatility of Cyclodextrins in Pharmaceutical Formulations

edited by

Łukasz Szeleszczuk

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2940 | Submission Open

Keywords: cyclodextrins; CDs; inclusion complexes; cyclodextrin-based nanosponges; excipients; host– guest complexes; complexes

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Application of Marine-Derived Polymers in Drug Dosage Forms

edited by

Marta Szekalska

and

Katarzyna Sosnowska

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2831 | Submission Open

Keywords: pharmaceutical formulations; controlled drug release; biological activity of drug fromulations; marine-derived polymers; alginates; chitosan; fucoidan

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Conjugated Polymer Nanoparticles: Innovative Designs for Photodynamic and Photothermal Therapy in Cancer and Bacterial Infections—Preclinical Evaluation and Beyond

edited by

Luis Ibarra

submission deadline 31 Dec 2025 | 3 articles | Viewed by 2785 | Submission Open

Keywords: conjugated polymer nanoparticles; organic semiconducting materials; biomedical application; drug delivery; preclinical evaluation; antimicrobial nanoparticles; antitumoral nanoparticles

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Next-Generation Biomaterials for Oral Healthcare: Focus on Regenerative and Delivery Functions

edited by

Giuseppina Nocca

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2522 | Submission Open

Keywords: oral drug delivery; biomaterials; mucoadhesive systems; nanotechnology; regenerative dentistry; oral tissue engineering; bioactive scaffolds; controlled drug release; oral mucosal drug absorption; smart biomaterials; in vitro and ex vivo models; oral healthcare innovation

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Extracellular Vesicles for Targeted Delivery

edited by

Beáta Soltész

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2313 | Submission Open

Keywords: computational approaches; drug delivery; engineered exosomes; exosomes; experimental approaches; extracellular vesicle-based delivery; extracellular vesicles; immunotherapy; nanomedicine; therapeutic cargo; therapy

(This special issue belongs to the Section Biologics and Biosimilars)

Advances in Radiopharmaceuticals: Enhancing Targeted Delivery, Disease Diagnosis, and Therapeutic Applications

edited by Kuan Hu and Volkan Tekin

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2225 | Submission Open

Keywords: radiopharmaceuticals; radiotherapy; diagnosis; therapy; targeting delivery

(This special issue belongs to the Section Clinical Pharmaceutics)

Bioactive Hydrogels as Multifunctional Dressing Materials

edited by

Jagoda Kurowiak

and Tomasz Klekiel

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1992 | Submission Open

Keywords: biocompatible hydrogels; functional materials; natural polymers; biohydrogels; dressings; hard-to-heal wounds; burns; bedsores; pharmaceuticals; active substances; anti-inflammatory and antibacterial drugs

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Cutting-Edge 3D Printing Technology for Drug Delivery and Tissue Engineering

edited by

Eliana Aparecida de Rezende Duek

, Moema Hausen and

Cecília de Barros

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1943 | Submission Open

Keywords: additive manufacturing; smart materials; bioactive molecules; drug delivery systems; tissue engineering; biomaterials for tissue healing; 3D scaffolds; cell therapy with biomaterials

(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)

Advanced Nanomaterials for Drug Delivery, 2nd Edition

edited by

Roxana Cristina Popescu

and

Diana Savu

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1855 | Submission Open

Keywords: nanomaterials; drug delivery systems; cancer therapy; antimicrobial applications; antiviral applications

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Advances and Challenges in Nanomedicine: Translating Nanotechnology into Therapeutics for Cancer, Neurodegenerative, and Infectious Diseases

edited by

Giovanna Della Porta

and

Erwin Pavel Lamparelli

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1755 | Submission Open

Keywords: nanomedicine; targeted delivery; gene therapies; immunotherapies; cancer; infectious diseases; neurological disorders

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Bioactive Molecules for Targeted Cancer Therapy and Delivery Innovations

edited by

Cristian O. Salas

and Felipe Andrés Oyarzún-Ampuero

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1571 | Submission Open

Keywords: bioactive molecules; targeted therapy; angiogenesis inhibitors; signal transduction inhibitors; nano and micromedicines; drug delivery; spatial and temporal drug release

(This special issue belongs to the Section Biologics and Biosimilars)

Recent Advances in Drug Delivery Using AI and Machine Learning

edited by

Glen S. Kwon

Hugh D. C. Smyth

, Chinmay S. Potnis and Rebeca T. Stiepel

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1385 | Submission Open

Keywords: nanoparticle drug delivery; artificial intelligence (AI); machine learning (ML); predictive modelling; targeted drug delivery; nanomedicine; excipient optimization; personalized drug formulations; computational drug design; AI-driven drug development

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Advances in Polymer-Based Devices and Platforms for Pain Management

edited by

Marcel Henrique Marcondes Sari

and

Luana Mota Ferreira

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1346 | Submission Open

Keywords: nanocarriers; biopolymers; analgesics; anti-inflammatory; nano-based formulations; nanoparticles; functional polymers; polymer-based platforms

(This special issue belongs to the Section Drug Targeting and Design)

Application of Polymeric Micelles for Drug and Gene Delivery, 2nd Edition

edited by

Stanislav Rangelov

and

Emi Haladjova

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1280 | Submission Open

Keywords: polymeric micelles; micelleplexes; drug delivery; gene delivery; drug release; nanomedicine; gene therapy; theranostics

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Natural Macromolecule-Based Nanocarriers for Drug Delivery

edited by

Lipeng Qiu

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1201 | Submission Open

Keywords: macromolecules; polysaccharides; proteins; nucleic acids; lipids; nanocarrier; drug delivery; targeted delivery; controlled release

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Nanotechnology Advances for Breast Cancer Treatment

edited by

Marlus Chorilli

, Marcela Tavares Luiz and Pietro Rosemeire Cristina Linhari Rodrigues

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1184 | Submission Open

Keywords: active targeting; breast cancer; cancer therapy; drug delivery systems; nanoparticles; nanosystems

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Advancements in AI and Pharmacokinetics

edited by

Raj Sewduth

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1104 | Submission Open

Keywords: AI in nanomedicine; drug targeting; pharmacokinetics; pharmacodynamics; drug– receptor interactions

(This special issue belongs to the Section Drug Targeting and Design)

Multifunctional Nanomaterials in Drug Delivery

edited by

Ranjit De

submission deadline 31 Dec 2025 | 1 articles | Viewed by 981 | Submission Open

Keywords: nanomaterials; bioavailability; targeting efficiency; controlled release; drug delivery

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Natural Product Pharmaceuticals, 2nd Edition

edited by

Maria Rosaria Lauro

submission deadline 31 Dec 2025 | 1 articles | Viewed by 926 | Submission Open

Keywords: pre-formulation and formulation studies; natural compounds; herbal extracts; chemical– physical and technological studies; extraction methods; stability and stabilization; in vitro and in vivo biological activities; pharmacokinetics and pharmacological studies; analytical techniques

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Innovations in Ungual and Dermal Drug Delivery Systems for Localized Therapies

edited by

Letícia Scherer Koester

and

Helder Teixeira

submission deadline 31 Dec 2025 | 1 articles | Viewed by 879 | Submission Open

Keywords: nano-based formulations; hydrogel-based formulations; 3D-printed formulations; films; biocompatibility; ungual; dermal; in vitro release testing (IVRT); in vitro permeation testing (IVPT)

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Nanocarriers and Delivery Systems for Next-Generation Nanomedicine Therapies

edited by

Wei Huang

submission deadline 31 Dec 2025 | 1 articles | Viewed by 641 | Submission Open

Keywords: nanocarriers; targeted delivery systems; stimuli-responsive materials; co-delivery systems; theranostic nanoplatforms; clinical translation

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Advances in Nanoparticle-Based Therapeutics: From Extracellular Vesicles to Metal Nanocarriers for Cancer Therapy

edited by Eleni K. Efthimiadou

submission deadline 31 Dec 2025 | Viewed by 624 | Submission Open

Keywords: nanoparticle; extracellular vesicle; metal-based nanotechnology; drug delivery; cancer

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Paediatric and Neonatal Specific Dosage Forms and Administration

edited by

Smita Salunke

and Fiona O'Brien

submission deadline 31 Dec 2025 | 1 articles | Viewed by 553 | Submission Open

Keywords: excipients safety; non-oral drug delivery; oral drug delivery; paediatric dosage forms; neonatal dosage forms; drug administration; age-appropriate formulations

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Unlocking Cancer Treatment: Harnessing Lipid Nanocarriers for Precision Drug Delivery

edited by Joydeb Majumder

submission deadline 31 Dec 2025 | Viewed by 368 | Submission Open

Keywords: cancer therapy; nano therapeutics; lipid nanoparticles; drug delivery; targeted delivery; nanomedicine

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Model-Informed Precision Dosing in Drug Development and Clinical Practice

edited by

Zhigang Wang

and

Bingfang Yan

submission deadline 31 Dec 2025 | Viewed by 355 | Submission Open

Keywords: model-informed precision dosing (MIPD); efficacy PKPD indexes; pharmacokinetics; pharmacodynamics; PKPD modeling and simulation; dosing algorithms; nomograms; drug development; therapeutic drug monitoring (TDM); dosing adjustments; special populations; nonlinear mixed-effects modeling (NONMEM); PK/PD models; drug– drug interactions; pediatrics; pregnancy; oral bioavailability; modelling and simulation; population pharmacokinetics

(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)

Application of PLGA Nanoparticles in Cancer Therapy

edited by

Daniele Rubert Nogueira-Librelotto

submission deadline 31 Dec 2025 | Viewed by 335 | Submission Open

Keywords: PLGA nanoparticles; cancer therapy; drug delivery; biocompatibility; controlled release; targeted therapy; theranostics; formulation strategies

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Microfluidic Assembly of Nanocomplexes for Drug and Gene Delivery

edited by Tiago Albertini Balbino and

Ismail Eş

submission deadline 31 Dec 2025 | Viewed by 317 | Submission Open

Keywords: microfluidics; nanocomplex assembly; drug delivery; gene delivery; polymer nanoparticle; lipid nanoparticle; process optimization; mRNA vaccine delivery

(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)

Nano-Drug Delivery Systems: Tackling Cancer Metabolism and Drug Resistance

edited by

Odília Queirós

submission deadline 31 Dec 2025 | Viewed by 313 | Submission Open

Keywords: nano-drug delivery systems; tumor microenvironment; cancer metabolism; metabolic reprogramming; drug resistance; targeted therapy; combination therapy

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Functional Polymers for Targeted Therapeutics and Gene Delivery

edited by Łukasz Sieroń and

Emanuela Fabiola Craparo

submission deadline 31 Dec 2025 | Viewed by 301 | Submission Open

Keywords: polymer; nanoparticle; nucleic acid delivery; targeted therapy; targeted delivery; gene therapy

(This special issue belongs to the Section Gene and Cell Therapy)

Multifunctional Hydrogels for Controlled Release of Bioactive Molecules

edited by

Diana C. Silva

Ana Paula Serro

and

Maria Vivero-Lopez

submission deadline 31 Dec 2025 | Viewed by 295 | Submission Open

Keywords: multifunctional hydrogels; biodegradable hydrogels; antimicrobial hydrogels; smart hydrogels; stimuli-responsive hydrogels; therapeutic hydrogels; nanogels; drug delivery; local drug delivery; controlled release; drug carriers; bioactive molecules; bioactive materials; biocompatible materials; hydrogel characterization; ex vivo and in vivo evaluation

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Advanced Drug Nanocrystals

edited by Nadia Araci Bou-Chacra

submission deadline 31 Dec 2025 | Viewed by 280 | Submission Open

Keywords: preparation of drug nanocrystals: key factors affecting their stability; quality by design (QbD) approach; critical quality attributes (CQAs); and process insights for the production of drug nanocrystals; scaling up and down: industrial applications of drug nanocrystals; characterization methods for drug nanocrystals; applications of drug nanocrystals across various drug delivery routes and therapies; in vivo fate and cellular uptake of drug nanocrystals: exploring pharmacokinetics and pharmacodynamics

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Design of Hydrogels for Drug Delivery

edited by

Luis Morales-Quintana

and

Bustos Daniel

submission deadline 31 Dec 2025 | Viewed by 263 | Submission Open

Keywords: drug delivery; controlled release; smart hydrogels; computational modelling of hydrogels; molecular simulations of hydrogels; bioresponsive systems; hydrogel fabrication techniques

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Advanced Research on Transdermal Drug Delivery

edited by

and

submission deadline 31 Dec 2025 | Viewed by 259 | Submission Open

Keywords: transdermal drug delivery; skin drug delivery; percutaneous drug delivery; topical drug delivery; microneedles; patches; hydrogels; creams

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Biopolymer Nanoparticles for Targeted Therapy in Cardiovascular Diseases

edited by Lino Sánchez-Segura and Silvio Zaina

submission deadline 31 Dec 2025 | Viewed by 226 | Submission Open

Keywords: nanoparticles; biopolymers; drug-load; drug delivery; target; cardiovascular disease; therapy

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Electrospun Fibers, Tissue Engineering, and Drug Delivery: Strategies and Potential Solutions for a Complex Issue

edited by Adrienn Kazsoki and

Constantinos Voniatis

submission deadline 31 Dec 2025 | Viewed by 205 | Submission Open

Keywords: electrospinning; fibrous mesh; drug delivery systems; biodegradable membranes; nanofibers; potential drug candidates for nanofibrous dosage forms

(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)