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Pharmaceutics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advancing Biologic Drug Development Through Physiologically Based Pharmacokinetic Modelling and Simulations

edited by

Victor Mangas Sanjuán

and Javier Reig Lopez

submission deadline 31 Mar 2026 | 6 articles | Viewed by 16434 | Submission Open

Keywords: monoclonal antibodies; antibody-drug conjugates; bispecific antibodies; PBPK; target-mediated drug disposition; lysosomal degradation; FcRn binding; special populations

(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)

Biotechnology Applications and Innovative Approaches for Cancer Prevention and Treatment (BIO-APP)

edited by

and

submission deadline 31 Mar 2026 | 4 articles | Viewed by 14233 | Submission Open

Keywords: applied biochemistry; biotechnologies; cancer; drug delivery; multitarget ligands; theranostics; biomarkers; point-of-care testing; sensitive nanomaterials

(This special issue belongs to the Section Biologics and Biosimilars)

Multifunctional Hydrogels for Controlled Drug Delivery

edited by

Cheng Hu

submission deadline 31 Mar 2026 | 1 articles | Viewed by 6520 | Submission Open

Keywords: multifunctional hydrogels; drug delivery; biomedical applications; targeted release; therapeutic effects

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Nasal Nanotechnology: What Do We Know and What Is Yet to Come?

edited by Rosario Pignatello and

Teresa Musumeci

submission deadline 31 Mar 2026 | 3 articles | Viewed by 4865 | Submission Open

Keywords: nasal drug delivery; polymeric and/or lipid nanocarriers; rhinitis; brain targeting; vaccines; nose-to-brain drug delivery; functionalization; ex vivo and in vivo studies; cytocompatibility/cytotoxicity; mucoadhesion; mucosal permeation

(This special issue belongs to the Section Drug Delivery and Controlled Release)

In Silico Pharmacokinetic and Pharmacodynamic (PK-PD) Modeling

edited by

Neal M. Davies

and

Raimar Löbenberg

submission deadline 31 Mar 2026 | 3 articles | Viewed by 4487 | Submission Open

Keywords: physiologically based pharmacokinetics (PBPKs); population pharmacokinetics (PopPKs); quantitative systems pharmacology (QSP); Bayesian modeling; artificial intelligence in PK-PD; in silico bioequivalence; multi-objective optimization; translational pharmacokinetics

(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)

Application of Stimuli-Sensitive Hydrogel for the Treatment of Human and Animal Diseases

edited by

Donato Cosco

and Elena Giuliano

submission deadline 31 Mar 2026 | 3 articles | Viewed by 3848 | Submission Open

Keywords: stimuli-responsive hydrogels; self healing; rheology; injectable systems; smart hydrogels

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Advanced Computational Tools in Development and Assessment of Dosage Form

edited by

Jakub Szlęk

and

Adam Pacławski

submission deadline 31 Mar 2026 | 1 articles | Viewed by 2832 | Submission Open

Keywords: artificial intelligence; computational tools; advanced imaging in drug development; pharmaceutical analysis; dosage form characterization; pharmaceutical process monitoring

(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)

Application of Silver Nanoparticles in Cancer Treatment

edited by

Serena Mazzucchelli

and Francesco Ragonese

submission deadline 31 Mar 2026 | 1 articles | Viewed by 2468 | Submission Open

Keywords: silver nanoparticles; nanomedicine; nanotechnology; cancer therapy; cancer diagnostics; cancer theranostics; tumor targeting; drug delivery systems; in vitro studies; in vivo studies

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Innovative Applications of Targeted Nanocarriers and Photodynamic Therapy in the Treatment of Neurological Diseases and Tumors

edited by

Emma Ortiz-Islas

Victoria Campos-Peña

and

Citlali Ekaterina Rodríguez Pérez

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1808 | Submission Open

Keywords: photodynamic therapy; neurological disorders; targeted nanocarriers; brain tumors; Alzheimer’ s disease; nanomedicine; drug delivery; reactive oxygen species; nano-photosensitizers

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Recent Advances in Nucleic Acid-Based Therapeutics, Vaccines, and Drug Delivery Vehicles

edited by

Samantha Meenach

and Ting-Yu Shih

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1599 | Submission Open

Keywords: immunotherapy; nucleic acid-based therapeutics and delivery; RNA vaccines; biomaterials; nanomaterials; autoimmune and neurological disorders’ treatment

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Nucleic-Acid-Based Strategies and Nanotechnology Applications for Targeted Therapy, 2nd Edition

edited by

Andrea Patrizia Falanga

submission deadline 31 Mar 2026 | 2 articles | Viewed by 1313 | Submission Open

Keywords: nucleic acids; drug delivery; nanomedicine; biotechnology; material science

(This special issue belongs to the Section Drug Targeting and Design)

Combining Ultrasound and Microbubbles/Nanobubbles for Enhancing the Effects of Cancer Therapies

edited by

Yi-Ju Ho

and

Deepa Sharma

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1173 | Submission Open

Keywords: ultrasound; immunotherapy; radiation therapy; chemotherapy; micro/nano-bubble; cancer therapeutics; drug delivery

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Dendrimers in Nanomedicine: Recent Advances

edited by

Anne-Marie Caminade

submission deadline 31 Mar 2026 | 1 articles | Viewed by 959 | Submission Open

Keywords: dendrimers; dendritic nanostructures; biological properties; diagnosis; imaging agents; carriers; drug delivery; drug therapy; nanomedicine

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Site-Specific Drug Delivery

edited by

Yunjin Jung

submission deadline 31 Mar 2026 | 1 articles | Viewed by 775 | Submission Open

Keywords: site-specific drug delivery; targeted drug delivery; therapeutic effectiveness; nanotechnology; biological barrier

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Biomaterials for Oral and Dental Drug Delivery

edited by

Magdalena Paczkowska-Walendowska

and

Judyta Cielecka-Piontek

submission deadline 31 Mar 2026 | 1 articles | Viewed by 702 | Submission Open

Keywords: oral drug delivery; dental drug delivery; biomaterials; mucoadhesive systems; tissue regeneration; periodontal therapy

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Formulation, Characterization, and Performance Testing of Topical Semisolid Products

edited by

Michael Roberts

and Seeprarani Rath

submission deadline 31 Mar 2026 | Viewed by 676 | Submission Open

Keywords: formulation of topical semisolid dosage forms; characterization of topical semisolid dosage forms; microstructure; in vitro release and permeation testing; bioavailability and bioequivalence; topical and transdermal delivery; quality-by-design

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Hydrogels for Localized and Controlled Drug Delivery

edited by

Roberta Censi

and Cristina Casadidio

submission deadline 31 Mar 2026 | 1 articles | Viewed by 488 | Submission Open

Keywords: hydrogels; drug Delivery; cancer; tissue engineering; wound healing

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Natural Innovations in Pharmaceutical Formulation: From Traditional Remedies to Modern Drug Carriers

edited by

Titus Vlase

submission deadline 31 Mar 2026 | Viewed by 418 | Submission Open

Keywords: formulation science; natural products; natural compounds; drug carriers; novel drug delivery platforms

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Polymeric Films as a Multipurpose Drug Delivery System: Application, Properties, Preparation and Evaluation

edited by

Jurga Bernatoniene

and

Yuliia Maslii

submission deadline 31 Mar 2026 | Viewed by 352 | Submission Open

Keywords: drug delivery system; polymers; polymeric films; physicochemical and texture characteristics; film production techniques; controlled and sustained release; adhesion; bioavailability; formulation; evaluation

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Bio-Nanoparticle Systems for Brain Drug Delivery

edited by

Valentina Pagliara

and

Raffaella D'Auria

submission deadline 31 Mar 2026 | Viewed by 327 | Submission Open

Keywords: bio-nanoparticles; brain drug delivery; blood-brain barrier; neurological disorders; targeted nanomedicine

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Advances in Parenteral Drug Delivery and Parenteral Formulations

edited by

Eduardo Ruiz-Hernandez

and Dorota Wątróbska-Świetlikowska

submission deadline 31 Mar 2026 | Viewed by 259 | Submission Open

Keywords: parenteral formulation; parenteral nutrition; injectable formulation; implants; intravenous; intramuscular; subcutaneous; long-acting injectables; nanosphere; submicron emulsion

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Peptide Polymer Delivery Systems for Antibacterial and Immunomodulatory Applications

edited by Hashem Etayash

submission deadline 31 Mar 2026 | Viewed by 253 | Submission Open

Keywords: antimicrobial peptides; host defense peptides; bacterial infection; biofilms; immunomodulatory agents; drug resistance; antibiotics; surafe-tethered peptides; peptide formulation; peptide polymers

(This special issue belongs to the Section Biologics and Biosimilars)

Microneedle-Mediated Transdermal Delivery of Bio-Macromolecular Drugs

edited by Guangsheng Du and Li Deng

submission deadline 31 Mar 2026 | Viewed by 179 | Submission Open

Keywords: microneedle; transdermal delivery; dermal delivery; bio-macromolecular drugs; minimally invasive; skin delivery; therapeutic biologics

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Ultrasound‑Enhanced Drug Delivery: Applications and Therapeutic Advances

edited by

Gail Ter Haar

and

Petros Mouratidis

submission deadline 31 Mar 2026 | Viewed by 175 | Submission Open

Keywords: therapeutic ultrasound; high‑intensity focused ultrasound (HIFU); focused ultrasound surgery (FUS); histotripsy; sonoporation; sonodynamic therapy; drug delivery; microbubbles; nanoparticles; cancer; neurodegenerative conditions

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Oligonucleotide Aptamers for Diagnostics and Therapy

edited by

Claudia Riccardi

and

Ettore Napolitano

submission deadline 31 Mar 2026 | Viewed by 174 | Submission Open

Keywords: aptamers; oligonucleotides; therapy; diagnostics; targeted drug delivery; molecular recognition; aptamer engineering; protein– aptamer interactions; aptamer-based nanotechnology

(This special issue belongs to the Section Gene and Cell Therapy)

Targeted Drug Delivery in Brain Tumor Microenvironments

edited by

Chiara Bastiancich

and Phoebe McCrorie

submission deadline 31 Mar 2026 | Viewed by 171 | Submission Open

Keywords: neuro-oncology; drug delivery; tumour microenvironment; targeted drug delivery; glioblastoma; medulloblastoma

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Biological Barriers in Health and Disease, 2nd Edition

edited by

Neuhaus Winfried

Gert Fricker

and

Mária A. Deli

submission deadline 31 Mar 2026 | Viewed by 164 | Submission Open

Keywords: drug transport; transport protein regulation; blood– brain barrier; epithelial barriers; gut barrier; respiratory barriers; blood– saliva barrier; cell culture; organoid and chip models; biological barriers and pathological changes; protection of biological barriers in diseases; targeted drug delivery systems and nanoparticles to cross barriers

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Therapeutic Drug Monitoring for Individualized Cancer Therapy

edited by Petra Turčić and Lu Turković

submission deadline 31 Mar 2026 | Viewed by 163 | Submission Open

Keywords: personalized medicine; pharmacometrics; population pharmacokinetics and pharmacodynamics (PK-PD); nonlinear mixed-effects modeling (NONMEM); targeted anticancer drugs; clinical pharmacy and pharmacology; kinase inhibitors; monoclonal antibodies (mAbs); bioanalytical method development and validation; (non-)adherence

(This special issue belongs to the Section Clinical Pharmaceutics)

Combatting Infections: The Role of Antibacterial Natural Products and Nanoparticles

edited by Iwona Skiba-Kurek and

Carla Zannella

submission deadline 31 Mar 2026 | Viewed by 160 | Submission Open

Keywords: multidrug-resistant bacteria; antibacterial compounds; antimicrobial nanoparticles; silver; zinc and copper nanoparticles; skin and wound infections; antibacterial mushroom extracts; dressings

(This special issue belongs to the Section Drug Targeting and Design)

Emerging Stimuli-Responsive Nanoparticles for Bioactive Delivery

edited by

Marc Schneider

and Sangeun Lee

submission deadline 31 Mar 2026 | Viewed by 158 | Submission Open

Keywords: disease microenvironment; smart nanoparticles; biofunctional nanomedicine

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

New Approach Methodologies in Biopharmaceutics: Towards a More Humane Drug Development

edited by

Miguel Ángel Cabrera-Pérez

, Daniel Hachim and

Mauricio A. García

submission deadline 31 Mar 2026 | Viewed by 153 | Submission Open

Keywords: biopharmaceutics; new approach methodologies; model and simulations; organoids; organ-on-a-chip; biorelevant in vitro dissolution; In vitro permeability; effect of excipients; biopharmaceutic-oriented drug development

(This special issue belongs to the Section Biopharmaceutics)

Cutting-Edge Approaches to Smart Pharmaceutics and Vaccine Development

edited by

Andreea-Teodora Iacob

submission deadline 31 Mar 2026 | Viewed by 147 | Submission Open

Keywords: nanotechnology-driven innovations; modern vaccines; smart pharmaceutics; AI-assisted pharmaceuticals

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Shape Memory Polymers for Drug Delivery and Tissue Engineering

edited by

Silvia Pisani

submission deadline 31 Mar 2026 | Viewed by 140 | Submission Open

Keywords: shape memory polymers; smart biomaterials; drug delivery system; tissue engineering; regenerative medicine; controlled release; biomedical applications; electrospinning; 3D printing; microfluidic

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Phytochemicals and Bioactive Compound-Based Pharmaceutical Formulations in Health and Disease: From Mechanisms to Therapeutic Applications

edited by

Lucas Fornari Laurindo

submission deadline 31 Mar 2026 | Viewed by 136 | Submission Open

Keywords: phytochemicals and bioactive compounds; pharmaceutical formulations; therapeutics; delivery systems; pharmacokinetics; in vitro and in vivo studies

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Novel Strategies for Enhancing Oral Bioavailability

edited by

Naibo Yin

and

Paul William Richard Harris

submission deadline 31 Mar 2026 | Viewed by 134 | Submission Open

Keywords: oral; formulation; delivery system; chemical modification; pro-drug; analogue

(This special issue belongs to the Section Biopharmaceutics)

Advances in Oral Drug Delivery Systems

edited by Gioconda Millotti

submission deadline 31 Mar 2026 | Viewed by 125 | Submission Open

Keywords: oral drug delivery; oral formulation; nanotechnology; polymer-based carrier; lipid-based carrier

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Nanotechnology and Cell Therapies for Ocular Diseases

edited by

Raid Alany

and

Ovidiu Samoilă

submission deadline 31 Mar 2026 | Viewed by 121 | Submission Open

Keywords: nanotechnology; limbal stem cells; cell cultivation techniques; eye barriers; drug delivery systems; retinal degenerations

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Microparticle Platforms for Respiratory Delivery

edited by

Dae Hwan Shin

and Hye Jin Lee

submission deadline 31 Mar 2026 | Viewed by 119 | Submission Open

Keywords: pulmonary drug delivery; inhalation therapy; controlled release; respiratory diseases

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Design and Evaluation of Pharmaceutical Co-Crystallization: Integration of Structural Analysis and Pharmacodynamic Assessment

edited by

Dezhi Yang

and Li Zhang

submission deadline 31 Mar 2026 | Viewed by 118 | Submission Open

Keywords: pharmaceutical co-crystals; structural analysis; pharmacodynamic assessment; crystal engineering; drug solubility enhancement; structure– property relationships; computational screening; bioavailability; solid-state characterization; rational drug design

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Biomedical Applications: Advances in Bioengineering and Drug Delivery, 2nd Edition

edited by María Carolina Otero and

Yusser Olguín

submission deadline 31 Mar 2026 | Viewed by 115 | Submission Open

Keywords: biomedicine; tissue engineering; biomaterials; drug carrier; biological therapy

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Formulations for Anti-Inflammatory Efficacy

edited by Bruna Chiari-Andréo

submission deadline 31 Mar 2026 | Viewed by 109 | Submission Open

Keywords: inflammation; steroidal anti-inflammatory drugs; non-steroidal anti-inflammatory drugs; natural anti-inflammatory drugs; efficacy and safety.

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Advanced Nanocarriers for Targeted Drug Delivery in Inflammation-Associated Diseases

edited by Ana Laura López-Machado and

Rossella Laurano

submission deadline 31 Mar 2026 | Viewed by 83 | Submission Open

Keywords: control release; drug delivery systems; inflammation-associated diseases; liposomes; micelles; nanocarriers; polymeric nanoparticles

(This special issue belongs to the Section Drug Delivery and Controlled Release)

To Instill, to Deliver, to Implant, to Incise, to Protect: Innovations in Glaucoma Management—a Pharmaceutical Perspective

edited by Luca Agnifili, Matteo Sacchi and

Michele Figus

submission deadline 31 Mar 2026 | Viewed by 77 | Submission Open

Keywords: glaucoma; medical therapy; drug formulation; drug delivery systems; pharmaceutical biotechnology; implantable devices; pharmacokinetics; pharmacodynamics; laser therapy; minimally invasive glaucoma surgery; neuroprotection; gene therapy; neuroregeneration

(This special issue belongs to the Section Clinical Pharmaceutics)

Skin Care Products for Healthy and Diseased Skin, 2nd Edition

edited by Nina Dragićević

submission deadline 31 Mar 2026 | Viewed by 76 | Submission Open

Keywords: skin care products; skin delivery; healthy skin; diseased skin; nanoparticle-based products; natural emulsifiers

(This special issue belongs to the Section Drug Targeting and Design)

Recent Insights Concerning the Use of Supramolecular Systems for Biomedical Applications

edited by

Elena-Alina Moacă

Codruta Soica

Cristina Trandafirescu

and

Cristina Adriana Dehelean

submission deadline 10 Apr 2026 | 4 articles | Viewed by 6714 | Submission Open

Keywords: nanotransporters; drug carrier; drug delivery systems; cancer therapy; supramolecular systems; biological activity; physicochemical properties; nanoplatforms; nanoformulation; biomolecules; hydrogels; polymers; manufacturing techniques

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Functional Nanomaterials for Drug Delivery in Photodynamic Therapy

edited by

Enrico Caruso

and

Miryam Chiara Malacarne

submission deadline 10 Apr 2026 | 3 articles | Viewed by 6278 | Submission Open

Keywords: nanomaterials; drug delivery systems; photodynamic therapy; targeted therapies; third-generation photosensitizers; targeting agents

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Recent Advances in Gastrointestinal Disease: Insights into Drug Delivery and Cellular and Molecular Mechanisms for Therapy

edited by

Amilcare Barca

and

Emanuele Piccinno

submission deadline 10 Apr 2026 | 2 articles | Viewed by 2282 | Submission Open

Keywords: gastrointestinal disease; drug delivery; molecular therapy; biological therapy; target therapy; molecular target; biomarkers; GI epithelial cells

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Personalized Medicine: Integrating Pharmacogenetics and Pharmacokinetics

edited by

Sétondji Cocou Modeste Alexandre Yahouédéhou

and

Elżbieta Wyska

submission deadline 10 Apr 2026 | 1 articles | Viewed by 661 | Submission Open

Keywords: personalized medicine; pharmacogenetics; pharmacokinetics; drug metabolism; genetic variations; therapeutic response; drug dosage optimization

(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)

Research on the Development of Semi-Solid Pharmaceutical Dosage Forms and Self-Emulsifying Drug Delivery Systems

edited by

Pálma Fehér

and

Liza Józsa

submission deadline 15 Apr 2026 | 3 articles | Viewed by 7369 | Submission Open

Keywords: semi-solid dosage forms; ointments; creams; gels; transdermal patches; self-emulsifying drug delivery systems; topical delivery; transdermal delivery

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Mechanism-Based Pharmacokinetic and Pharmacodynamic Modeling

edited by

Artur Świerczek

submission deadline 20 Apr 2026 | 6 articles | Viewed by 16831 | Submission Open

Keywords: PK/PD modeling; disease progression modeling; quantitative system pharmacology; physiologically based modeling

(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)

Displaying special issue 151-200 on page 4 of 9.

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