Nanoemulsions for Nose-to-Brain Drug Delivery
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 1394
Special Issue Editors
Interests: perillyl alcohol; glioblastoma; pharmacokinetics of nanoparticles; nanomedicine; intranasal delivery
Interests: nanotechnology in drug delivery; bioavailability enhancement; nanostructured drug formulations; pharmacokinetics of nanoparticles; nanomedicine
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue focuses on the emerging field of “Nanoemulsions for Nose-to-Brain Drug Delivery” via intranasal administration, targeting enhanced treatment of central nervous system (CNS) disorders. The complex structure of the blood–brain barrier (BBB) presents a significant obstacle in delivering therapeutic agents to the brain. Nanoemulsions, with their submicron droplet size and high surface area, offer a unique means to bypass the BBB by leveraging the olfactory and trigeminal pathways, allowing for direct drug transport from the nasal cavity to the brain. This approach enables both rapid absorption and reduced systemic circulation, optimizing therapeutic outcomes. We invite submissions on innovative formulation techniques, stability studies, pharmacokinetic profiles, and the experimental validation of CNS-targeted nanoemulsions via olfactory and trigeminal routes. Additionally, this Special Issue welcomes insights into the biocompatibility and regulatory challenges of nanoemulsion formulations in neurological applications, alongside interdisciplinary studies bridging pharmaceutical nanotechnology, bioengineering, and neuroscience.
Dr. Clóvis Orlando Pereira Da Fonseca
Dr. Rubiana Mara Mainardes
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- nanoemulsion
- intranasal
- pharmacokinetics
- nose-to-brain
- neurology
- olfactory
- nanomedicine
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
