Special Issues

Pharmaceuticals publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Development of Antibacterial Drugs to Combat Drug-Resistant Bacteria: 2nd Edition
edited by and Iryna Voronkina
submission deadline 31 Jan 2026 | Viewed by 68 | Submission Open
Keywords: development of antibacterial drugs; drug-resistant bacteria; antimicrobial resistance; new therapeutic solutions; improvement of existing therapies; nosocomial infections
(This special issue belongs to the Section Pharmacology)
Natural Products for Skin Applications submission deadline 31 Jan 2026 | Viewed by 55 | Submission Open
Keywords: bioactive compounds; plant extracts; topic preparations; skincare; cutaneous applications; skin cancer; medicinal plants; modern extraction techniques; optimized/standardized extracts; phytochemical analysis; health outcomes of plant extracts; bioaccessability of compounds from various vegetal matrices; drug– vegetal extract interactions at metabolic level
(This special issue belongs to the Section Natural Products)
Design, Synthesis and Biological Evaluation of Small Molecules for the Treatment of Solid Tumors submission deadline 31 Jan 2026 | Viewed by 44 | Submission Open
Keywords: anticancer drugs; small-molecule agents; targeted therapy; solid cancers; drug delivery systems; drug resistance; approval characteristic; FDA; EMA
(This special issue belongs to the Section Medicinal Chemistry)
Promising Natural Products with Anti-Inflammatory and Antioxidant Bioactivities: Extraction, Identification, and Biological Evaluation
edited by Sara Vieira and
submission deadline 31 Jan 2026 | Viewed by 27 | Submission Open
Keywords: bioactive compounds; extraction techniques; anti-inflammatory activity; antioxidant activity; inflammation; inflammatory molecules; signaling pathways
(This special issue belongs to the Section Natural Products)
Radiopharmaceuticals in Cancer Disorders: Clinical and Pharmaceutical Perspectives
edited by
submission deadline 31 Jan 2026 | Viewed by 26 | Submission Open
Keywords: radiopharmaceuticals; cancer theranostics; targeted radionuclide therapy; molecular imaging; pharmaceutical development
(This special issue belongs to the Section Radiopharmaceutical Sciences)
Drug Therapy for Rheumatological Diseases
edited by
submission deadline 31 Jan 2026 | Viewed by 18 | Submission Open
Keywords: rheumatology; drug therapy; biologics; DMARDs; therapeutic drug monitoring; shared decision-making; autoimmune diseases; chronic disease management; safety vs. efficacy of rheumatic disease therapy
(This special issue belongs to the Section Pharmacology)
Pharmaceutical Blood Products
edited by , Masaki Otagiri and
submission deadline 31 Jan 2026 | Viewed by 6 | Submission Open
Keywords: pharmaceutical blood products; plasma-derived therapeutics; recombinant blood factors; cellular therapies; immunoglobulins; fractionation technologies; viral inactivation; hemophilia treatments; gene-editing approaches; clinical efficacy
(This special issue belongs to the Section Biopharmaceuticals)
Advances in Targeted Therapy for Gastrointestinal Cancers submission deadline 31 Jan 2026 | Viewed by 5 | Submission Open
Keywords: targeted therapy; gastrointestinal cancers; molecular targets; drug resistance; biomarkers; immunotherapy; precision medicine; translational research; clinical trials; tumor microenvironment
(This special issue belongs to the Section Pharmacology)
Advances in Topical and Mucosal Drug Delivery Systems submission deadline 15 Feb 2026 | 1 articles | Viewed by 566 | Submission Open
Keywords: topical drug delivery; mucosal drug delivery; transdermal drug delivery; controlled release; bioavailability enhancement; formulation development
(This special issue belongs to the Section Pharmaceutical Technology)
Chemotherapeutic and Targeted Drugs in Antitumor Therapy submission deadline 15 Feb 2026 | Viewed by 416 | Submission Open
Keywords: cancer; drug discovery; small-molecule drugs; targeted therapy; combination therapy; synergism; selectivity; immunotherapy; precision medicine
(This special issue belongs to the Section Pharmacology)
Click Chemistry-Aided Drug Discovery
edited by
submission deadline 15 Feb 2026 | Viewed by 20 | Submission Open
Keywords: click chemistry; drug discovery; structure– activity relationship; hit-to-lead; chemical probes; bio-orthogonal reactions; protein-templated reactions; bioisosteres; cycloaddition; 1; 2; 3-triazole
(This special issue belongs to the Section Medicinal Chemistry)
Application of Zebrafish Model in Pharmacology and Toxicology submission deadline 15 Feb 2026 | Submission Open
Keywords: chemical safety assessment; translational research; drug screening; human exposome; environmental contaminants
(This special issue belongs to the Section Pharmacology)
Medicinal Plants: A Natural Approach to Inflammatory Diseases and Conditions Related to Oxidative Stress submission deadline 25 Feb 2026 | 6 articles | Viewed by 11454 | Submission Open
Keywords: medicinal plants; phytocompounds; natural products; inflammatory diseases; oxidative stress
(This special issue belongs to the Section Natural Products)
Advances in Biotechnological Formulations for Skin Disorders: Delivery Strategies and Biocompatibility
edited by Marcel Henrique Marcondes Sari, and
submission deadline 25 Feb 2026 | 1 articles | Viewed by 2044 | Submission Open
Keywords: skin disorders; biotechnological formulations; nanocarriers; probiotic-based formulations; natural products; polysaccharides; skin delivery systems; bioactive compounds; antioxidant and anti-inflammatory effects; wound healing; safety and efficacy in skin therapies
(This special issue belongs to the Section Pharmaceutical Technology)
Targeting Epigenetic Regulation for Cancer Therapy submission deadline 25 Feb 2026 | Viewed by 61 | Submission Open
Keywords: epigenetics; chromatin remodeling; histone modifications; non-coding  RNAs; gene regulation; cancer therapy; epigenetic biomarkers; therapeutic targets
(This special issue belongs to the Section Pharmacology)
Advances in Perinatal Pharmacology submission deadline 25 Feb 2026 | Submission Open
Keywords: maternal; perinatal; neonatal; pharmacology; placenta; pregnancy
(This special issue belongs to the Section Pharmacology)
Advances in the Mechanism of Action and the Therapeutic Role of Phytopharmaceuticals
edited by Maria-Eleni Grafakou and
submission deadline 28 Feb 2026 | 1 articles | Viewed by 819 | Submission Open
Keywords: medicinal plants; natural products; phytochemistry; biological activities; mechanism of action; biotransformation; microbiome
(This special issue belongs to the Section Natural Products)
New Horizons in Drug Development Targeting Depression
edited by , Joanna Fojcik, Agnieszka Koźmin-Burzyńska and Marek Krzystanek
submission deadline 28 Feb 2026 | Viewed by 306 | Submission Open
Keywords: treatment-resistant depression; novel antidepressants; glutamatergic system; personalized medicine; psychoactive therapies
(This special issue belongs to the Section Pharmacology)
Pyrazole and Its Derivatives: Drug Design, Synthesis, and Biological Evaluation submission deadline 28 Feb 2026 | Viewed by 85 | Submission Open
Keywords: medicinal chemistry; drug design; drug discovery; pyrazole-based compounds; innovative synthesis; structure– activity relationships; biological activities; drug-like properties
(This special issue belongs to the Section Medicinal Chemistry)
Molecular Insights and Clinical Implications in Geriatric Medicine and Drug Development
edited by , , Kornelia Kędziora-Kornatowska and
submission deadline 28 Feb 2026 | Viewed by 52 | Submission Open
Keywords: older adults; age-related diseases; biomarkers; drug development; molecular modeling; computer-aided drug design; geriatrics in laboratory medicine; laboratory tests in older patients; malnutrition diagnostics; test results versus a clinical image of an older patient
(This special issue belongs to the Section Pharmacology)
Discovery of Natural Products to Promote the Wound Healing
edited by
submission deadline 28 Feb 2026 | Viewed by 10 | Submission Open
Keywords: natural ingredients; natural biomedical polymers; drug delivery; nanomedicine; hydrogels; wound healing
The Emerging Field of Critical Care Psychiatry: Pharmacologic Treatment from ICU to Post-ICU Recovery
edited by Shixie Jiang, and Jose R. Maldonado
submission deadline 28 Feb 2026 | Viewed by 9 | Submission Open
Keywords: critical care psychiatry; ICU psychiatry; delirium; encephalopathy; cognitive impairment; neurocognitive disorders; dementia; post-intensive care syndrome; depression; anxiety; trauma; insomnia; sleep disturbances; mental health; behavioral health
(This special issue belongs to the Section Pharmacology)
Vitamin D and Its Derivatives in Pharmacology: Mechanisms and Therapeutic Applications submission deadline 28 Feb 2026 | Viewed by 8 | Submission Open
Keywords: vitamin D; synthesis and metabolism; vitamin D derivatives; vitamin D deficiency related diseases; clinical trials on vitamin D and/or its derivatives
(This special issue belongs to the Section Pharmacology)
Advances in Natural Products: Basic, Therapeutic, and Computational Approaches in Chronic and Infectious Diseases submission deadline 28 Feb 2026 | Viewed by 8 | Submission Open
Keywords: natural products; chronic diseases; infectious diseases; computational; in silico
(This special issue belongs to the Section Natural Products)
Bioactive Substances and Skin Health: The Role of Pharmacy and Nutrition—Properties and Technology
edited by , Margarita López-Viota and Rafael Jesús Giménez Martínez
submission deadline 1 Mar 2026 | 4 articles | Viewed by 16544 | Submission Open
Keywords: supplements; bioactive substances; skin health
(This special issue belongs to the Section Pharmaceutical Technology)
Medications: Interactions with Diet, Herbs, Dietary Supplements and Probiotics
edited by , María Isabel Valverde Merino and Maria José Zarzuelo Romero
submission deadline 1 Mar 2026 | 3 articles | Viewed by 6785 | Submission Open
Keywords: food– drug interactions; dietary supplements; probiotics; herb– drug interaction
(This special issue belongs to the Section Pharmacology)
Innovations in Chemotherapy: From Synthetic to Natural Agents and Combined Therapies
edited by Stefano Ruga
submission deadline 1 Mar 2026 | Viewed by 149 | Submission Open
Keywords: chemotherapy; immunotherapy; innovative drugs; natural compounds; combination therapy; targeted therapy; customized administration; drug stability; drug storage
(This special issue belongs to the Section Pharmacology)
Exploring Natural Products with Antioxidant and Anticancer Properties, 2nd Edition submission deadline 25 Mar 2026 | Viewed by 5 | Submission Open
Keywords: antioxidant; anticancer; neoplasms; natural products; cytotoxicity
(This special issue belongs to the Section Natural Products)
Discovery and Validation of Novel Antimicrobial Molecules for the Treatment of Multidrug-Resistant Bacterial Infections
edited by and Rocco Latorre
submission deadline 27 Mar 2026 | Viewed by 211 | Submission Open
Keywords: antibiotics therapy; multidrug resistance; bacterial infection
(This special issue belongs to the Section Pharmacology)
Peptide-Based Drug Discovery: Innovations and Breakthroughs
edited by
submission deadline 31 Mar 2026 | Viewed by 44 | Submission Open
Keywords: drug discovery; peptide-based compounds; peptidomimetics; target modulation; structure– activity relationship studies; hit molecules; AI-driven drug discovery; ligand-based drug design; structure-based drug design; computer-aided drug design
(This special issue belongs to the Section Medicinal Chemistry)
Design, Synthesis and Pharmacological Evaluation of Novel Opioid/Non-Opioid Hybrid Compounds
edited by Justyna Piekielna-Ciesielska and
submission deadline 31 Mar 2026 | Viewed by 20 | Submission Open
Keywords: opioid; opioid hybrids; pain; opioid-related side-effects; tolerance; addiction; neurotransmitters
(This special issue belongs to the Section Medicinal Chemistry)
Natural Products and Bioactive Compounds for the Prevention and Treatment of Non-Communicable Chronic Diseases
edited by
submission deadline 26 Apr 2026 | Viewed by 13 | Submission Open
Keywords: natural products; phytochemicals; chronic diseases; functional foods; herbal medicine; non-communicable diseases; ethnopharmacology; bioactivity
(This special issue belongs to the Section Natural Products)
Computational Methods in Drug Development
edited by
submission deadline 26 May 2026 | 7 articles | Viewed by 9931 | Submission Open
Keywords: computational modeling; DNA/RNA and protein; drug discovery and design; systems biology; channels and membranes; biomedical data analysis; artificial intelligence; molecule docking and scoring
(This special issue belongs to the Section Medicinal Chemistry)
Applications of Stem Cells and Organoids in Disease Modeling, Drug Discovery and Clinical Evaluation
edited by Daniela Omodei
submission deadline 31 May 2026 | Viewed by 24 | Submission Open
Keywords: stem cells; patient-derived cells; iPSCs (induced pluripotent stem cells); organoids; drug development; drug screening; drug toxicity; preclinical and clinical drug research; novel therapeutics; disease modeling; personalized medicine; precision medicine
(This special issue belongs to the Section Pharmacology)
Extracts and Essential Oils from Medicinal Plants: Biological Activities, Applications, and Perspectives submission deadline 30 Jun 2026 | Viewed by 51 | Submission Open
Keywords: medicinal plants; spices and herbs; bioactive compounds; antimicrobial agents; plant extracts; essential oils; phytochemical analysis; microbiological analysis; natural medicines
(This special issue belongs to the Section Natural Products)
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