Special Issues

Pharmaceuticals publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Natural Products as an Alternative for Treatment of Human Diseases
edited by Eduardo Lira, and Raimundo Gonçalves De Oliveira Junior
submission deadline 25 Jun 2026 | 9 articles | Viewed by 24251 | Submission Open
Keywords: medicinal plants; herbal remedies; natural products; traditional medicine
(This special issue belongs to the Section Natural Products)
Photodynamic Therapy: 3rd Edition
edited by
submission deadline 25 Jun 2026 | 5 articles | Viewed by 6059 | Submission Open
Keywords: photodynamic therapy; photosensitizers; nanoparticles; photo-diagnosis; targeting; antimicrobial; X-rays excitation; two photon and upconversion; immunomodulation; dosimetry; hypoxia
(This special issue belongs to the Section Pharmaceutical Technology)
Plant-Derived Products in the Treatment of Internal Diseases: 2nd Edition
edited by and
submission deadline 25 Jun 2026 | 3 articles | Viewed by 4816 | Submission Open
Keywords: medicinal plants; phytotherapy; herbal treatment; natural products; herbalism; traditional medicine; cardiovascular disease; lung disease; liver disease; gastrointestinal disease; kidney disease; obesity; diabetes; rheumatological disease
(This special issue belongs to the Section Natural Products)
Pharmaceutical Applications of Cannabinoids submission deadline 25 Jun 2026 | 1 articles | Viewed by 2837 | Submission Open
Keywords: cannabis; cannabinoids; therapeutic properties; medicinal plant; phytochemicals
Secondary Metabolites as Drug Leads: Bridging Experimental Discovery and Computational Innovation
edited by , Francisco das Chagas Alves Lima, , Luisa Di Paola and
submission deadline 25 Jun 2026 | 1 articles | Viewed by 617 | Submission Open
Keywords: medicinal chemistry; computer aided-drug design; new drugs agents; natural products
(This special issue belongs to the Section Medicinal Chemistry)
HIV and Viral Hepatitis Prevention, Treatment and Coinfection, 2nd Edition submission deadline 25 Jun 2026 | Viewed by 303 | Submission Open
Keywords: coinfection; drug discovery; HBV; HCV; HDV; HIV; neutralizing antibodies; prevention; treatment; vaccine
(This special issue belongs to the Section Biopharmaceuticals)
Bioactive Substances, Oxidative Stress, and Inflammation, 2nd Edition submission deadline 25 Jun 2026 | Viewed by 246 | Submission Open
Keywords: bioactive compounds; oxidative stress; chronic inflammation; chronic non-communicable diseases; polyphenol; vitamins; omega-3 fatty acids
(This special issue belongs to the Section Natural Products)
Epidemiological Surveillance of Clinical Bacterial Infections and Antimicrobial Resistance Management submission deadline 25 Jun 2026 | Viewed by 138 | Submission Open
Keywords: antimicrobial resistance (AMR); clinical bacterial infections; epidemiological surveillance; antimicrobial stewardship (AMS); drug-resistant pathogens; rapid diagnostic tools for AMR; pharmacokinetics/pharmacodynamics (PK/PD) of antimicrobials; infection control; multi-center surveillance data; public health policy for AMR
(This special issue belongs to the Section Pharmacology)
Advances in Drug Hypersensitivity Research
edited by José Antonio Cornejo-García
submission deadline 25 Jun 2026 | Viewed by 123 | Submission Open
Keywords: drug hypersensitivity/allergic reactions; IgE antibodies; T-cells; non-immunological reactions; antibiotics; NSAIDs; anaesthetics; chemotherapeutics; biologicals  
(This special issue belongs to the Section Pharmacology)
Extracellular Vesicles and Bioinspired Nanovesicles as Next-Generation Drug-Delivery Systems
edited by
submission deadline 25 Jun 2026 | Viewed by 109 | Submission Open
Keywords: extracellular vesicles; bioinspired nanovesicles; drug-delivery systems; therapeutics; exosomes; exosome-like nanoparticles; hybrid exosomes
(This special issue belongs to the Section Biopharmaceuticals)
Self-Assembling Materials for Next-Generation Biopharmaceuticals
edited by
submission deadline 25 Jun 2026 | Viewed by 106 | Submission Open
Keywords: peptide self-assembly; peptide drug design; drug-loaded nanostructures; biomaterials; AI-driven design
(This special issue belongs to the Section Biopharmaceuticals)
Gut Microbiota and Metabolites: Novel Strategies for Intestinal Inflammation Therapy
edited by Alexander S. Dowdell
submission deadline 25 Jun 2026 | Viewed by 76 | Submission Open
Keywords: inflammatory bowel disease; Crohn’ s disease; Ulcerative colitis; gut microbiota; IBD therapies; IBD treatments  
(This special issue belongs to the Section Biopharmaceuticals)
Pharmacological Interventions for Opioid-Induced Respiratory Depression
edited by David Matthew Walentiny
submission deadline 25 Jun 2026 | Viewed by 62 | Submission Open
Keywords: opioid; respiratory depression; medication development; overdose; wooden chest syndrome; apnea; polysubstance; medicinal chemistry
(This special issue belongs to the Section Medicinal Chemistry)
New and Emerging Treatment Strategies for Gastrointestinal Diseases, 2nd Edition submission deadline 25 Jun 2026 | Viewed by 40 | Submission Open
Keywords: gastrointestinal diseases; gastrointestinal homeostasis; gastrointestinal injuries; gastrointestinal disturbances; dysbiosis; bile acid; inflammatory bowel diseases; diarrhea
(This special issue belongs to the Section Pharmacology)
Treatment for HPV-Associated Cervical Cancer: Novel Therapeutic Strategies
edited by , , Marco Antonio Leyva-Vázquez, and Olga Lilia Garibay-Cerdenares
submission deadline 26 Jun 2026 | Viewed by 266 | Submission Open
Keywords: cervical cancer; proteomic; transcriptomic; miRNA; lncRNA; drug repositioning; nano-transport; liposomes and immunoliposomes
(This special issue belongs to the Section Pharmacology)
Chirality in Drugs
edited by
submission deadline 26 Jun 2026 | Viewed by 185 | Submission Open
Keywords: chirality; chiral drugs; chiral resolution; asymmetric synthesis; chiral analysis; chiroptical spectroscopy
(This special issue belongs to the Section Medicinal Chemistry)
Targeted Radiopharmaceutical Therapies: Cutting-Edge Advances
edited by Noeen Malik
submission deadline 26 Jun 2026 | Viewed by 148 | Submission Open
Keywords: targeted radiopharmaceutical therapies (TRT); radiopharmaceuticals; radionuclide therapy; molecular radiotherapy; radioisotopes; radiochemistry; isotope production; radionuclide delivery; preclinical evaluation; clinical translation
(This special issue belongs to the Section Radiopharmaceutical Sciences)
Use of Anesthetic Agents: Management and New Strategy: 2nd Edition submission deadline 26 Jun 2026 | Viewed by 93 | Submission Open
Keywords: anesthetic agents; anesthetic drugs; anesthetic; general anesthetic agents; therapeutic tools
(This special issue belongs to the Section Pharmacology)
Selective Histone Deacetylase Isoforms as Potential Therapeutic Targets
edited by
submission deadline 30 Jun 2026 | 7 articles | Viewed by 24618 | Submission Open
(This special issue belongs to the Section Medicinal Chemistry)
Boron-Containing Compounds: Identification, Synthesis, Biological Actions and Pharmacology submission deadline 30 Jun 2026 | 11 articles | Viewed by 17114 | Submission Open
Keywords: boron; drug development; drug discovery; bioactive boron compounds; bioinorganic chemistry; inorganic biological chemistry; synthesis; natural boron compounds; chemical characterization
(This special issue belongs to the Section Medicinal Chemistry)
Nanotechnology in Biomedical Applications submission deadline 30 Jun 2026 | 8 articles | Viewed by 11043 | Submission Open
Keywords: nanotechnology; nanobiotechnology; biomedical applications; drug delivery; nanobiosensors; targeted therapy; diagnostics; nanomaterials; therapeutics; theranostics
(This special issue belongs to the Section Pharmaceutical Technology)
Therapeutic Potential of Cannabinoid Receptors Type 1 and 2—Novel Insights for Enhancing the Chance of Clinical Success, 2nd Edition
edited by
submission deadline 30 Jun 2026 | 3 articles | Viewed by 9109 | Submission Open
Keywords: endocannabinoid system (ECS); cannabinoid receptor type 1 (CB1R); cannabinoid receptor type 2 (CB2R); cannabinoids; ligand
(This special issue belongs to the Section Pharmacology)
Pharmaceutical Applications and Therapeutic Mechanisms of Substances from Plant Origin
edited by Iliya Zhelev Slavov, , and
submission deadline 30 Jun 2026 | 5 articles | Viewed by 9029 | Submission Open
Keywords: natural substances; phytotherapy; phytochemistry; chromatography; pharmacokinetics; pharmacodynamics; drug delivery
(This special issue belongs to the Section Natural Products)
Novel Heterocyclic Compounds as Potential Anti-Inflammatory and/or Anticancer Agents
edited by Ester Colarusso and
submission deadline 30 Jun 2026 | 1 articles | Viewed by 4731 | Submission Open
Keywords: drug discovery; medicinal chemistry; privileged scaffolds; heterocyclic compounds; anticancer activity; anti-inflammatory activity
(This special issue belongs to the Section Medicinal Chemistry)
Pharmaceuticals for Inflammatory Bowel Disease (IBD)
edited by
submission deadline 30 Jun 2026 | 1 articles | Viewed by 3426 | Submission Open
Keywords: inflammatory bowel disease; IBD symptoms; IBD pathogenesis; IBD treatments
(This special issue belongs to the Section Pharmacology)
Recent Advances in the Research of Drug Delivery System: Materials, Preparation Methods, and Mechanisms
edited by
submission deadline 30 Jun 2026 | 2 articles | Viewed by 3133 | Submission Open
Keywords: drug delivery system; preparation; material; mechanism; application; bioactivities; targeted delivery
(This special issue belongs to the Section Pharmaceutical Technology)
Next-Generation Antinfective Agents submission deadline 30 Jun 2026 | 1 articles | Viewed by 2093 | Submission Open
Keywords: small molecules; peptides; peptidomimetics; bacterial infections; fungi; virus; parasites; drug design; computational tools; biology assays; resistance mechanisms
(This special issue belongs to the Section Medicinal Chemistry)
Characterization and Quality Control of Biopharmaceuticals Using the Multi-Attribute Method (MAM): Advantages and Challenges
edited by Jingzhong Guo
submission deadline 30 Jun 2026 | 1 articles | Viewed by 1952 | Submission Open
Keywords: analytical characterization; critical quality attribute (CQA); the multi-attribute method (MAM); new peak detection (NPD); post-translational modifications (PTM); product quality attribute (PQA); peptide mapping (PM); quality by design (QbD); quality control (QC); structure– activity relationship (SAR)
(This special issue belongs to the Section Biopharmaceuticals)
Advances in Regulatory Mechanisms and Therapeutic Potential of Non-Coding RNAs in Neurodegenerative Diseases
edited by and Maurizio Grassano
submission deadline 30 Jun 2026 | 2 articles | Viewed by 1837 | Submission Open
Keywords: non-coding RNAs; microRNAs; long non-coding RNAs; circular RNAs; neurodegeneration; Alzheimer's disease; Parkinson's disease; amyotrophic lateral sclerosis; gene regulation; biomarkers; RNA therapeutics; neuroinflammation; synaptic dysfunction; translational neuroscience
(This special issue belongs to the Section Biopharmaceuticals)
Advances in Smooth Muscle Pharmacology
edited by , Tomasz Kleszczewski and
submission deadline 30 Jun 2026 | 1 articles | Viewed by 1657 | Submission Open
Keywords: smooth muscle regulation; pharmacological interventions; ion channel modulation; receptor– ligand dynamics; therapeutic drug development; vascular tone regulation; smooth muscle disorders; translational pharmacology; cellular signaling pathways; pathophysiology
(This special issue belongs to the Section Pharmacology)
Advances in Enzyme Inhibitors and Protein Degraders as Anticancer Agents
edited by and
submission deadline 30 Jun 2026 | 2 articles | Viewed by 1541 | Submission Open
Keywords: anticancer agents; mechanism of action; epigenetics; PROTAC; antibody– drug conjugates; enzymes
(This special issue belongs to the Section Medicinal Chemistry)
Extracts and Essential Oils from Medicinal Plants: Biological Activities, Applications, and Perspectives submission deadline 30 Jun 2026 | 1 articles | Viewed by 1142 | Submission Open
Keywords: medicinal plants; spices and herbs; bioactive compounds; antimicrobial agents; plant extracts; essential oils; phytochemical analysis; microbiological analysis; natural medicines
(This special issue belongs to the Section Natural Products)
Advances in Non-Coding RNAs as Prognostic Biomarkers, Therapeutic Targets, and Regulatory Mechanisms in Cancer submission deadline 30 Jun 2026 | 1 articles | Viewed by 982 | Submission Open
Keywords: non-coding RNAs; non-coding RNAs as prognostic biomarkers in cancer; non-coding RNAs as treatment targets in cancer; non-coding RNAs as diagnostic targets in cancer; molecular mechanisms on non-coding RNAs in cancer
(This special issue belongs to the Section Biopharmaceuticals)
Novel Developments in Antileishmanial and Antitrypanosomal Agents
edited by , Guillermo Labadie and Brian Suárez Mantilla
submission deadline 30 Jun 2026 | 2 articles | Viewed by 835 | Submission Open
Keywords: antileishmanial; antitrypanosomal; Chagas disease; human African Trypanosomiasis (sleeping sickness); leishmaniasis; drug discovery; medicinal chemistry; natural products; drug repurposing; trypanosomatids
(This special issue belongs to the Section Medicinal Chemistry)
Novel Drug Candidates for the Treatment of Cardiac and Renal Diseases
edited by , and Diana Barrera-Oviedo
submission deadline 30 Jun 2026 | 1 articles | Viewed by 670 | Submission Open
Keywords: kidney diseases; cardiac diseases; cardiorenal syndrome; treatments; chronic kidney diseases; drugs; dyslipidemia; oxidative stress
(This special issue belongs to the Section Pharmacology)
Antifungal Therapy Strategies: A Focus on Novel Compounds and Inhibitors submission deadline 30 Jun 2026 | 1 articles | Viewed by 666 | Submission Open
Keywords: medicinal chemistry; combined therapy; antivirulence action; anti-resistance strategies; drug repositioning; drug delivery; multi-omics technologies
(This special issue belongs to the Section Medicinal Chemistry)
Pharmacovigilance in Drug Therapy and Adverse Reactions
edited by
submission deadline 30 Jun 2026 | Viewed by 268 | Submission Open
Keywords: pharmacovigilance; adverse reactions; drug safety; artificial intelligence; biological drugs; high-impact diseases
(This special issue belongs to the Section Pharmacology)
Advances in Analytical Method Development for Pharmaceutical Formulations submission deadline 30 Jun 2026 | Viewed by 229 | Submission Open
Keywords: pharmaceutical analysis; sample preparation; chromatographic techniques; solid-state characterization; particle size determination; vibrational spectroscopy; X-ray diffraction; thermal techniques; microscopy
(This special issue belongs to the Section Pharmaceutical Technology)
Selected Papers from the 1st International Electronic Conference on Medicinal Chemistry and Pharmaceutics (ECMC-P2025) submission deadline 30 Jun 2026 | Viewed by 219 | Submission Open
Keywords: small molecules as drug candidates; biomolecules; natural products; phages; and cells as therapeutic tools; biological targets and biomarkers; radiopharmaceutical sciences; radiochemistry; (hybrid) imaging; and nuclear medicine; nanotechnology; pharmacokinetics and pharmacodynamics; pharmaceutical preparations and drug delivery
(This special issue belongs to the Section Medicinal Chemistry)
Curcumin: Current Status and Future Challenges in Drug Delivery and Advanced Formulations submission deadline 30 Jun 2026 | Viewed by 189 | Submission Open
Keywords: curcumin; curcumin delivery; curcumin formulations; therapeutic potential; natural polyphenols; phytochemicals; nanotechnology; pharmacological properties
(This special issue belongs to the Section Pharmacology)
The Potential Role of Natural Bioactive Compounds in the Protection of Renal Function
edited by
submission deadline 30 Jun 2026 | Viewed by 163 | Submission Open
Keywords: natural bioactive compounds; renal health; oxidative stress; healthspan extension; chronic kidney disease; chronic non-communicable diseases; decline in renal function; biological pathways
(This special issue belongs to the Section Natural Products)
Monitoring, Mitigation, and Risk Assessment of Pharmaceuticals in the Environment submission deadline 30 Jun 2026 | Viewed by 140 | Submission Open
Keywords: pharmaceuticals; environmental impact; novel analytical techniques; remediation strategies; risk assessment; ecological effects
(This special issue belongs to the Section Pharmaceutical Technology)
Drugs and Implants in Orthopedic Surgery and Traumatology
edited by
submission deadline 30 Jun 2026 | Viewed by 137 | Submission Open
Keywords: drug– device combinations; orthopedic and trauma implants; local drug delivery; periprosthetic joint infection (PJI); biofilm prevention; antimicrobial coatings; antibiotic‑loaded bone cement; release kinetics (PK/PD); bioresorbable implants; fracture healing and bone regeneration
(This special issue belongs to the Section Pharmaceutical Technology)
Polysulfide Pharmacology: Biological Effects and Therapeutic Potential in Pain, Inflammation, and CNS Disorders
edited by Gábor Pozsgai
submission deadline 30 Jun 2026 | Viewed by 118 | Submission Open
Keywords: polysulfides; organic polysulfide derivatives; polysulfide pharmacology; polysulfide biology
(This special issue belongs to the Section Pharmacology)
Ferroptosis in Cancer and Beyond: Mechanisms, Biomarkers, and Interventions
edited by Hareesh B. Nair
submission deadline 30 Jun 2026 | Viewed by 114 | Submission Open
Keywords: ferroptosis therapeutics; GPX4/FSP1 axis; lipid peroxidation biomarkers; cancer and tissue protection; translational/clinical development
(This special issue belongs to the Section Pharmacology)
Advances in Ocular Drug Delivery: Emerging Technologies for the Anterior Segment
edited by Raquel Gil-Cazorla and Affiong Iyire
submission deadline 30 Jun 2026 | Viewed by 104 | Submission Open
Keywords: ocular drug delivery; anterior segment; sustained-release systems; nanotechnology; novel delivery platforms
(This special issue belongs to the Section Pharmaceutical Technology)
Novel Bioactive Compounds Targeting Urinary Tract Disorders
edited by
submission deadline 30 Jun 2026 | Viewed by 89 | Submission Open
Keywords: bioactive compounds; urinary tract disorders; nephroprotective agents; urolithiasis therapy; pharmacotherapy
(This special issue belongs to the Section Natural Products)
Artificial Intelligence: New Molecules, Therapeutic Targets and Discovery of New Drugs
edited by , Maria José Zarzuelo Romero and Margarita López-Viota
submission deadline 30 Jun 2026 | Viewed by 73 | Submission Open
Keywords: artificial intelligence; drug design; pharmaceutical technology; molecular dynamics simulation
(This special issue belongs to the Section AI in Drug Development)
Drug Development and Emerging Pharmacotherapies in Stroke Management
edited by Federica Ferrari and
submission deadline 30 Jun 2026 | Viewed by 65 | Submission Open
Keywords: brain ischemic stroke; cerebral hemorrhage; drug discovery; neuroprotection; immunomodulation; blood– brain barrier; drug delivery; biomarkers; neurorepair; post-stroke depression/dementia/spasticity
(This special issue belongs to the Section Pharmacology)
Antibody-Functionalized Nanomedicines for Targeted Therapy
edited by Pie Huda and
submission deadline 30 Jun 2026 | Viewed by 56 | Submission Open
Keywords: antibody– drug conjugates; antibody fragments; nanomedicine; radiotherapy; RNA/DNA delivery systems; theranostics; immunotherapy; targeted drug delivery
(This special issue belongs to the Section Pharmaceutical Technology)
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