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Pharmaceuticals publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Applications of Stem Cells and Organoids in Disease Modeling, Drug Discovery and Clinical Evaluation

edited by Daniela Omodei

submission deadline 31 May 2026 | Viewed by 113 | Submission Open

Keywords: stem cells; patient-derived cells; iPSCs (induced pluripotent stem cells); organoids; drug development; drug screening; drug toxicity; preclinical and clinical drug research; novel therapeutics; disease modeling; personalized medicine; precision medicine

(This special issue belongs to the Section Pharmacology)

Drug Candidates for the Treatment of Obesity, 3rd Edition

edited by

Maria Isabel Cardoso Alonso-Vale

and

Monica Marques Telles

submission deadline 31 May 2026 | Viewed by 54 | Submission Open

Keywords: obesity ; appetite supressors ; nutraceuticals ; plant extracts ; lipid metabolism ; high-fat diet ; adipogenesis

(This special issue belongs to the Section Medicinal Chemistry)

Pharmacological Treatments for Parasitic Diseases

edited by Maria Dichiara and

Giuliana Costanzo

submission deadline 31 May 2026 | Viewed by 31 | Submission Open

Keywords: parasitic diseases; antiparasitic agents; drug resistance; therapeutic strategies; drug discovery; neglected tropical diseases (NTDs); medicinal chemistry; global health

(This special issue belongs to the Section Medicinal Chemistry)

Anti-Fbibrosis Agent Development

edited by Younghwa Na

submission deadline 31 May 2026 | Viewed by 31 | Submission Open

Keywords: idiopathic pulmonary fibrosis (IPF); anti-fibrosis; drug discovery; combination therapies; personalized medicine

(This special issue belongs to the Section Medicinal Chemistry)

Emerging Technologies and Therapeutic Innovations for Neglected Tropical Diseases

edited by

Sandra Elisa Haas

submission deadline 31 May 2026 | Viewed by 4 | Submission Open

Keywords: neglected tropical diseases; nanoparticles; drug delivery systems; one health; therapeutic optimization; molecular targets; precision medicine; machine learning; artificial intelligence

(This special issue belongs to the Section Pharmaceutical Technology)

Epigenetic Regulatory Mechanisms and Applications of Non-Coding RNAs in Chemoresistance and Metabolic Disorders

edited by

Pía Loren Reyes

, Francisca Villagrán-Silva and Pablo J. Letelier

submission deadline 15 Jun 2026 | Viewed by 95 | Submission Open

Keywords: non-coding RNAs; epigenetic regulation; chemoresistance; metabolic disorders; chemotherapy-related toxicities; DNA methylation; histone modification; chromatin remodeling; RNA-based therapeutics; biomarkers

(This special issue belongs to the Section Biopharmaceuticals)

Allosteric Modulators: Unlocking New Dimensions from Molecular Discovery to Therapeutic Potential

edited by

Changho Han

Lisa Barbaro

and Kwangho Kim

submission deadline 20 Jun 2026 | Viewed by 66 | Submission Open

Keywords: allosteric binding sites; protein– ligand interactions; mechanism of action; isoform selectivity; signal bias; structure-based design; pharmacological profiling; allosteric anchoring; GPCRs; ion channels; kinases; heterobifunctional ligand; allosteric synergy

(This special issue belongs to the Section Medicinal Chemistry)

Tumor Therapy and Drug Delivery: 2nd Edition

edited by

Rositsa Mihaylova

submission deadline 20 Jun 2026 | Viewed by 15 | Submission Open

Keywords: antitumor therapy; drug-delivery systems; nanocarriers; immunoconjugates; nanotechnology; cancer selectivity

(This special issue belongs to the Section Pharmaceutical Technology)

Pharmaceutical Applications of Cannabinoids

edited by

Eduarda M. P. Silva

and

Carlos Ribeiro

submission deadline 25 Jun 2026 | 1 articles | Viewed by 1308 | Submission Open

Keywords: cannabis; cannabinoids; therapeutic properties; medicinal plant; phytochemicals

Epidemiological Surveillance of Clinical Bacterial Infections and Antimicrobial Resistance Management

edited by

Davide Carcione

and

Dario Cattaneo

submission deadline 25 Jun 2026 | Viewed by 52 | Submission Open

Keywords: antimicrobial resistance (AMR); clinical bacterial infections; epidemiological surveillance; antimicrobial stewardship (AMS); drug-resistant pathogens; rapid diagnostic tools for AMR; pharmacokinetics/pharmacodynamics (PK/PD) of antimicrobials; infection control; multi-center surveillance data; public health policy for AMR

(This special issue belongs to the Section Pharmacology)

Targeted Radiopharmaceutical Therapies: Cutting-Edge Advances

edited by Noeen Malik

submission deadline 26 Jun 2026 | Viewed by 58 | Submission Open

Keywords: targeted radiopharmaceutical therapies (TRT); radiopharmaceuticals; radionuclide therapy; molecular radiotherapy; radioisotopes; radiochemistry; isotope production; radionuclide delivery; preclinical evaluation; clinical translation

(This special issue belongs to the Section Radiopharmaceutical Sciences)

Therapeutic Potential of Cannabinoid Receptors Type 1 and 2—Novel Insights for Enhancing the Chance of Clinical Success, 2nd Edition

edited by

Uwe M. Grether

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2076 | Submission Open

Keywords: endocannabinoid system (ECS); cannabinoid receptor type 1 (CB1R); cannabinoid receptor type 2 (CB2R); cannabinoids; ligand

(This special issue belongs to the Section Pharmacology)

Characterization and Quality Control of Biopharmaceuticals Using the Multi-Attribute Method (MAM): Advantages and Challenges

edited by Jingzhong Guo

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1427 | Submission Open

Keywords: analytical characterization; critical quality attribute (CQA); the multi-attribute method (MAM); new peak detection (NPD); post-translational modifications (PTM); product quality attribute (PQA); peptide mapping (PM); quality by design (QbD); quality control (QC); structure– activity relationship (SAR)

(This special issue belongs to the Section Biopharmaceuticals)

Extracts and Essential Oils from Medicinal Plants: Biological Activities, Applications, and Perspectives

edited by

Stefan Tyski

Agnieszka E. Laudy

and

Mariola Kozłowska

submission deadline 30 Jun 2026 | 1 articles | Viewed by 824 | Submission Open

Keywords: medicinal plants; spices and herbs; bioactive compounds; antimicrobial agents; plant extracts; essential oils; phytochemical analysis; microbiological analysis; natural medicines

(This special issue belongs to the Section Natural Products)

Advances in Analytical Method Development for Pharmaceutical Formulations

edited by

Michail Lykouras

and

Malvina Orkoula

submission deadline 30 Jun 2026 | Viewed by 102 | Submission Open

Keywords: pharmaceutical analysis; sample preparation; chromatographic techniques; solid-state characterization; particle size determination; vibrational spectroscopy; X-ray diffraction; thermal techniques; microscopy

(This special issue belongs to the Section Pharmaceutical Technology)

Curcumin: Current Status and Future Challenges in Drug Delivery and Advanced Formulations

edited by

Valentina Paganini

and

Silvia Tampucci

submission deadline 30 Jun 2026 | Viewed by 100 | Submission Open

Keywords: curcumin; curcumin delivery; curcumin formulations; therapeutic potential; natural polyphenols; phytochemicals; nanotechnology; pharmacological properties

(This special issue belongs to the Section Pharmacology)

The Potential Role of Natural Bioactive Compounds in the Protection of Renal Function

edited by

Giulia Marrone

submission deadline 30 Jun 2026 | Viewed by 88 | Submission Open

Keywords: natural bioactive compounds; renal health; oxidative stress; healthspan extension; chronic kidney disease; chronic non-communicable diseases; decline in renal function; biological pathways

(This special issue belongs to the Section Natural Products)

Drugs and Implants in Orthopedic Surgery and Traumatology

edited by

Ioannis Stratos

submission deadline 30 Jun 2026 | Viewed by 80 | Submission Open

Keywords: drug– device combinations; orthopedic and trauma implants; local drug delivery; periprosthetic joint infection (PJI); biofilm prevention; antimicrobial coatings; antibiotic‑loaded bone cement; release kinetics (PK/PD); bioresorbable implants; fracture healing and bone regeneration

(This special issue belongs to the Section Pharmaceutical Technology)

Monitoring, Mitigation, and Risk Assessment of Pharmaceuticals in the Environment

edited by

Goreti Pereira

and

Vania Calisto

submission deadline 30 Jun 2026 | Viewed by 57 | Submission Open

Keywords: pharmaceuticals; environmental impact; novel analytical techniques; remediation strategies; risk assessment; ecological effects

(This special issue belongs to the Section Pharmaceutical Technology)

Advances in Ocular Drug Delivery: Emerging Technologies for the Anterior Segment

edited by Raquel Gil-Cazorla and Affiong Iyire

submission deadline 30 Jun 2026 | Viewed by 56 | Submission Open

Keywords: ocular drug delivery; anterior segment; sustained-release systems; nanotechnology; novel delivery platforms

(This special issue belongs to the Section Pharmaceutical Technology)

Ferroptosis in Cancer and Beyond: Mechanisms, Biomarkers, and Interventions

edited by Hareesh B. Nair

submission deadline 30 Jun 2026 | Viewed by 42 | Submission Open

Keywords: ferroptosis therapeutics; GPX4/FSP1 axis; lipid peroxidation biomarkers; cancer and tissue protection; translational/clinical development

(This special issue belongs to the Section Pharmacology)

Selected Papers from the 1st International Electronic Conference on Medicinal Chemistry and Pharmaceutics (ECMC-P2025)

edited by

Alfredo Berzal-Herranz

Patrick J. Sinko

and

Maria Emília De Sousa

submission deadline 30 Jun 2026 | Viewed by 21 | Submission Open

Keywords: small molecules as drug candidates; biomolecules; natural products; phages; and cells as therapeutic tools; biological targets and biomarkers; radiopharmaceutical sciences; radiochemistry; (hybrid) imaging; and nuclear medicine; nanotechnology; pharmacokinetics and pharmacodynamics; pharmaceutical preparations and drug delivery

(This special issue belongs to the Section Medicinal Chemistry)

G-Protein-Coupled Receptors as Therapeutic Targets for CNS Disorders

edited by

Fabio Del Bello

and Wilma Quaglia

submission deadline 24 Jul 2026 | Viewed by 83 | Submission Open

Keywords: GPCRs; CNS disorders; biased ligands; allosteric modulators; GPCR heteromers; multitarget ligands

(This special issue belongs to the Section Pharmacology)

Recent Advances in Medicinal Plants and Plant-Derived Compounds: Neuroprotective, Anti-Inflammatory, Antioxidant, Anticancer, and Antimicrobial Applications

edited by Isabel Martínez Solís,

Jose Ignacio Bueso-Bordils

and

Nuria Acero de Mesa

submission deadline 31 Jul 2026 | Viewed by 79 | Submission Open

Keywords: medicinal plants; bioactive compounds; neuroprotection; antioxidant activity; anti-inflammatory effects; anti-tumour properties; antimicrobial agents; phytotherapy; natural product-based therapeutics

(This special issue belongs to the Section Natural Products)

Multi-Targeted Natural Products as Therapeutics, 2nd Edition

edited by

Elena Y. Enioutina

Catherine M. T. Sherwin

and

Kathleen M. Job

submission deadline 30 Sep 2026 | Viewed by 84 | Submission Open

Keywords: natural products; medicinal herbs; marine products; animal products; bioactive compounds; multifactorial diseases; multi-targeting phytochemicals

(This special issue belongs to the Section Natural Products)

New Structural, Biophysical and Computational Perspectives on the Use of Proteins in Drug Design and Discovery

edited by

Marino F. A. Santos

Luís Passarinha

and

João Paquete-Ferreira

submission deadline 31 Oct 2026 | Viewed by 80 | Submission Open

Keywords: artificial intelligence; bioinformatics; computational modelling; drug discovery and design; functional proteomics; mass spectrometry; molecular dynamics; protein– ligand interactions; structural proteomics; structural biology; target identification and validation

(This special issue belongs to the Section Biopharmaceuticals)

Displaying special issue 351-400 on page 8 of 8.

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