Special Issues

Pharmaceuticals publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Bioactive Natural Products as Antitumoral Agents: Recent Advantages, Technology, Therapy, Applications and Future Perspectives
edited by , Javier Valverde-Pozo and Meriem Chayah
submission deadline 30 Nov 2026 | Viewed by 73 | Submission Open
Keywords: antitumoral compound synthesis; bioinorganic chemistry; physicochemical evaluation; innovative synthesis technologies; natural antitumoral analogues
(This special issue belongs to the Section Natural Products)
Anticancer Compounds in Medicinal Plants—4th Edition submission deadline 15 Dec 2026 | 3 articles | Viewed by 3343 | Submission Open
Keywords: natural products; phytochemicals; cancer; secondary metabolites; medicinal plants
(This special issue belongs to the Section Natural Products)
Metal-Based Nanoparticles’ Biological Activity and Pharmaceutical Applications, 2nd Edition submission deadline 20 Dec 2026 | 1 articles | Viewed by 1542 | Submission Open
Keywords: metal nanoparticles; redox reactions; biological activity; pharmaceuticals; cytotoxicity; antibacterial effect; oxidative stress; disease; safety; in vivo applications
(This special issue belongs to the Section Medicinal Chemistry)
Druggability of Mitochondrial Proteases: Emerging Targets and Therapeutic Opportunities in Cancer and Neurodegeneration submission deadline 20 Dec 2026 | Viewed by 285 | Submission Open
Keywords: mitochondrial proteostasis; druggability; mitochondrial proteases; UPRmt signaling; small-molecule modulators; medicinal chemistry; cancer therapy; neurodegenerative diseases
(This special issue belongs to the Section Medicinal Chemistry)
Development of Small Molecules as Immunomodulators and Adjuvants for Cancer Immunotherapy
edited by Laura Fioretto, and Mario Dell'Isola
submission deadline 20 Dec 2026 | Viewed by 48 | Submission Open
Keywords: cancer immunotherapy; organic synthesis; small molecules; cancer therapy; immunomodulators; adjuvants; immunology
(This special issue belongs to the Section Pharmacology)
Challenges in Discovering Innovations Related to Biofilms: Virulence, Spread, Control Strategies and Treatment submission deadline 25 Dec 2026 | 8 articles | Viewed by 14806 | Submission Open
Keywords: biofilm; structure; pathogenesis; virulence; tolerance; biofilm infections; dispersion; control strategies; quorum sensing
(This special issue belongs to the Section Pharmacology)
Pharmacological Activities of Flavonoids and Their Analogues, Third Edition submission deadline 25 Dec 2026 | 8 articles | Viewed by 9451 | Submission Open
Keywords: natural products; polyphenols; flavonoids; medicinal chemistry; traditional medicine; flavonoids isolation; flavonoids identification; flavonoids pharmacology; flavonoids as prodrugs; in vivo; in vitro; and in silico studies; molecular modeling studies
(This special issue belongs to the Section Natural Products)
Therapeutic Applications of Micro-RNA in Cancer Management—2nd Edition submission deadline 25 Dec 2026 | Viewed by 1 | Submission Open
Keywords: cancer; miRNAs; therapeutic applications; miRNA treatments
(This special issue belongs to the Section Biopharmaceuticals)
Innovations in Green Extraction and Analytical Techniques for Bioactive Natural Products
edited by
submission deadline 30 Dec 2026 | Viewed by 242 | Submission Open
Keywords: natural products; green extraction techniques; eco-friendly processes; sustainable isolation methods; analytical and preparative methodologies; chromatographic techniques; identification of bioactive compounds; bioactivity; quality control
(This special issue belongs to the Section Natural Products)
Novel Anticancer Drug Development and Toxicity Reduction Strategies
edited by
submission deadline 31 Dec 2026 | 5 articles | Viewed by 7859 | Submission Open
Keywords: cancer; targeted therapy; anticancer drug; structure-based computational technique; combination therapy; nanocarriers; hydrogels
(This special issue belongs to the Section Medicinal Chemistry)
Natural Products and Phytomedicines: From Chemical Profiling and Pharmacological Properties to Therapeutic Applications submission deadline 31 Dec 2026 | 8 articles | Viewed by 6521 | Submission Open
Keywords: natural products and derivatives; (nano)phytomedicine; plant extracts and phytopreparates; biochemical profiling; active principles; phytopharmacological mechanisms; signaling pathways; network pharmacology; molecular docking; pharmacokinetics and toxicity assays; clinical studies; therapeutic novelty; sustainable development
(This special issue belongs to the Section Natural Products)
Advances in Theranostic Radiopharmaceuticals
edited by
submission deadline 31 Dec 2026 | 2 articles | Viewed by 2721 | Submission Open
Keywords: theranostics; radiopharmacy; targeted alpha therapy; preclinical imaging; radiobiology; radioisotope production; molecular radiotherapy; positron emission tomography; single photon emission tomography
(This special issue belongs to the Section Radiopharmaceutical Sciences)
Pharmacotherapy of Macular Diseases
edited by
submission deadline 31 Dec 2026 | 1 articles | Viewed by 1329 | Submission Open
Keywords: VEGF inhibitors; macular disorders; neovascular age-related macular degeneration; diabetic macular edema; macular edema associated with retinal vein occlusion
(This special issue belongs to the Section Pharmacology)
Computational Predictions of Molecules with Potential Therapeutic Effects: 2nd Edition
edited by
submission deadline 31 Dec 2026 | 1 articles | Viewed by 1307 | Submission Open
Keywords: biophysics; medicinal chemistry; drug discovery; molecular docking; molecular dynamics; structure-activity relationships; computer-aided drug design (CADD)
(This special issue belongs to the Section Pharmacology)
Exploring Novel Therapies and Drug Efficacy for Inflammatory Bowel Disease submission deadline 31 Dec 2026 | 1 articles | Viewed by 1193 | Submission Open
Keywords: Crohn's disease; ulcerative colitis; pharmacology; antioxidants; novel therapies; gut microbiome; inflammation
(This special issue belongs to the Section Pharmacology)
Targeting the NLRP3: From Novel Inhibitor Design to Clinic Trials and Therapeutic Applications
edited by and
submission deadline 31 Dec 2026 | Viewed by 628 | Submission Open
Keywords: NLRP3 inflammasome; selective and direct NLRP3 inhibitors; drug discovery; clinical trial; therapeutic applications
(This special issue belongs to the Section Biopharmaceuticals)
Advances in Novel Drug Development Based on Drug Target Structure and Function
edited by Wanchao Yin
submission deadline 31 Dec 2026 | Viewed by 190 | Submission Open
Keywords: resolution revolution; cryo-EM; artificial intelligence; allosteric modulators; bias modulators; targeted protein degradation (TPD); molecular glues; molecular dynamics simulations; virtual screening; rational drug design
(This special issue belongs to the Section Pharmacology)
Targeting Neuroinflammation: Strategies for Drug Design of Therapeutic Agents and Molecular Imaging Probes submission deadline 31 Dec 2026 | Viewed by 184 | Submission Open
Keywords: neuroinflammation; P2X7 receptor; drug design and development; single-photon emission; computed tomography; tecnetium-99m
(This special issue belongs to the Section Radiopharmaceutical Sciences)
Hematological Malignancies: From Drug Discovery Targets to Precision Medicine
edited by and Irma Olarte Carrillo
submission deadline 31 Dec 2026 | Viewed by 39 | Submission Open
Keywords: hematological malignancies; leukemia; lymphoma; myelodysplastic syndrome; multiple myeloma; lymphoblastic leukemia; myeloid leukemia; drug discovery; target therapy; precision medicine
(This special issue belongs to the Section Pharmacology)
Natural Bioactive Compounds from Plants: Progress in Phytochemistry, Computational Approaches and Biomedical Applications submission deadline 31 Dec 2026 | Viewed by 25 | Submission Open
Keywords: natural products; medicinal plants; biomedical; computational; in silico
(This special issue belongs to the Section Natural Products)
Natural Products and Their Modifications as Agents Used in the Fight Against Pathogens, 2nd Edition
edited by
submission deadline 27 Jan 2027 | 2 articles | Viewed by 3313 | Submission Open
Keywords: plant extract; natural compounds; multidrug-resistant strains; intestinal microbiota; chemical modyfication; biotransformation
(This special issue belongs to the Section Natural Products)
A Commemorative Special Issue in Honor of Professor Eliezer J. Barreiro: Early Drug Discovery: From Target Identification and Validation to Lead Optimization submission deadline 31 Jan 2027 | 4 articles | Viewed by 9838 | Submission Open
Keywords: target validation; LBDD; FBDD; SBDD; QSAR; artificial intelligence; organic synthesis; natural product; drug discovery; medicinal chemistry
(This special issue belongs to the Section Medicinal Chemistry)
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