Pharmacological Activity and Application of Polyphenolic Compounds
A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Natural Products".
Deadline for manuscript submissions: 15 October 2025 | Viewed by 877
Special Issue Editor
2. CICS/UBI, Universidade da Beira Interior, Covilhã, Portugal
Interests: bioactive compounds; phytochemicals; natural products as health promoters; chronic diseases
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
A class of metabolites known as phenolic compounds is produced by secondary pathways in plants. Phenolic compounds can be found naturally in fruits, vegetables, cereals, roots, and leaves, which include flavonoids, phenolic acids, tannins, lignans, and coumarins. These play roles in various aspects of foods, including flavour, colour, astringency, and odour. These natural sources and their by-products, which are rich in phenolic compounds, have several applications in food additives, pharmaceutical formulations, and cosmetics, making them important health promoters. Recently, phenolic compounds have received particular interest because of their anti-inflammatory, anti-cancer, antioxidant, antibacterial, and cardiovascular protective properties. In addition, several studies have shown that eating vegetables can boost metabolic markers typically linked to a number of non-communicable diseases, such as diabetes, high blood pressure, and obesity. These phenolic compounds are sensitive to environmental factors (light, temperature, etc.) and processing conditions (interactions with other molecules, pH, and thermal treatments). Finding methods to stabilise them using technologies that provide protection from deterioration factors is therefore becoming more important. One practical and efficient way to maintain the bioactivity of phenolic compounds is to encapsulate them. By encasing the phenolic compounds in a polymeric matrix, encapsulation preserves the bioactive substances and permits their release under specific circumstances. This increases the bioavailability and bioaccessibility of phenolic compounds by regulating their release in particular target areas.
Dr. Luís Silva
Guest Editor
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Keywords
- phenolic compounds
- biological potential
- pharmacological activity
- phenolic applications
- health promoters
- chronic diseases
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