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Pharmaceuticals publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Pharmacovigilance in Drug Therapy: Drug–Drug Interactions and Safety Evaluation, 2nd Edition

edited by

Jacques Turgeon

submission deadline 31 Mar 2025 | 1 articles | Viewed by 885 | Submission Open

Keywords: pharmacovigilance; multi-drug interactions; clinical decision support systems; drug safety; drug side-effects; drug– drug interactions

(This special issue belongs to the Section Pharmacology)

Unveiling Nature's Pharmacy: Exploring Drug Discovery Through Medicinal Plants

edited by

Guglielmina Froldi

submission deadline 31 Mar 2025 | 1 articles | Viewed by 875 | Submission Open

Keywords: plant-derived drugs; secondary metabolites; advanced glycation end-products (AGEs); reactive oxygen species (ROS); molecular targets; pharmacokinetics; ADMET; bioavailability

(This special issue belongs to the Section Natural Products)

Advances in the Chemical-Biological Knowledge of Essential Oils

edited by

Andrea Maxia

and Emma Cocco

submission deadline 31 Mar 2025 | 1 articles | Viewed by 862 | Submission Open

Keywords: essential oils (EOs); volatile compounds; chemical composition; biological activity; traditional botanical knowledge

(This special issue belongs to the Section Natural Products)

Application of 3D Printing Technologies for Drug Delivery

edited by

Eleftherios G. Andriotis

submission deadline 31 Mar 2025 | 1 articles | Viewed by 712 | Submission Open

Keywords: additive manufacturing; 3D printing; drug delivery systems; personalized dosage forms; personalized drug delivery systems

(This special issue belongs to the Section Pharmaceutical Technology)

Drug Discovery, Development, and Synthesis for Glioblastoma

edited by

Shizue Mito

, Sue Anne Chew and

Mitsuhiro Arisawa

submission deadline 31 Mar 2025 | 1 articles | Viewed by 415 | Submission Open

Keywords: glioblastoma; drug design; drug synthesis; anticancer; natural products; biomolecules; combination therapy; pharmaceuticals

(This special issue belongs to the Section Pharmacology)

Development of Copper-Based Drugs: Synthesis, Characterisation and Biological Activity

edited by

Anita Kornicka

and

Łukasz Balewski

submission deadline 31 Mar 2025 | Viewed by 314 | Submission Open

Keywords: copper; copper coordination compounds; biologically active agents; radiopharmaceuticals; drug development; drug design

(This special issue belongs to the Section Medicinal Chemistry)

Advanced Nanosystems and Emerging Therapies: Innovations in Tuberculosis Treatment and Drug Resistance

edited by

Fernando Rogério Pavan

submission deadline 31 Mar 2025 | Viewed by 127 | Submission Open

Keywords: nanosystems; tuberculosis therapy; drug delivery; multidrug-resistant Mycobacterium tuberculosis (MDR-TB); nanotechnology-based therapeutics

(This special issue belongs to the Section Pharmaceutical Technology)

Integrating Machine Learning (ML) into Medicinal Chemistry and Cheminformatics

edited by

Vartika Tomar

submission deadline 31 Mar 2025 | Viewed by 126 | Submission Open

Keywords: small molecules; molecular descriptors; molecular similarity; structure-based and ligand-based screening; homology modeling; molecular docking; drug– receptor docking; biological activity

(This special issue belongs to the Section Medicinal Chemistry)

Drug Discovery and Development for Parasitic Diseases

edited by

Francois Dufrasne

submission deadline 31 Mar 2025 | Viewed by 102 | Submission Open

Keywords: parasitic diseases; biological activity; synthesis; pharmacology; medicine; chemistry; target

(This special issue belongs to the Section Medicinal Chemistry)

New Advances in Mesenchymal Stromal Cells as Therapeutic Tools, 2nd Edition

edited by

Kelen Cristina Ribeiro Malmegrim

submission deadline 31 Mar 2025 | Viewed by 98 | Submission Open

Keywords: mesenchymal stromal cells; cell therapy; immunomodulation; regeneration; regenerative medicine; bioprocessing; bioengineering; inflammatory diseases; degenerative diseases

(This special issue belongs to the Section Biopharmaceuticals)

Progress in the Development and Medical Applications of PET/SPECT Radiotracers and Theranostics

edited by

Giuseppe Carlucci

submission deadline 31 Mar 2025 | Viewed by 86 | Submission Open

Keywords: PET (Positron Emission Tomography); SPECT (Single-Photon Emission Computed Tomography); radiotracer chemistry; radiotracers; radiopharmaceutical

(This special issue belongs to the Section Radiopharmaceutical Sciences)

Green Synthesis and Biological Evaluation of Quinazolinone-Based Compounds

edited by Mario Komar,

Marija Paurević

and

Maja Molnar

submission deadline 31 Mar 2025 | Viewed by 74 | Submission Open

Keywords: synthesis in deep eutectic solvents; microwave-assisted synthesis; ultrasound-assisted synthesis; mechanochemical synthesis; quinazolinones; biological activity; computational methods

(This special issue belongs to the Section Medicinal Chemistry)

Synthesis and Biological Activity of Metal Complexes

edited by

Francois Dufrasne

submission deadline 31 Mar 2025 | Viewed by 74 | Submission Open

Keywords: metal complexes; biological activity; synthesis; pharmacology; cancer; pathogens; medicine; chemistry; stability; target

(This special issue belongs to the Section Medicinal Chemistry)

Pharmacotherapy for Alzheimer’s Disease

edited by

Gabriela Dumitrița Stanciu

submission deadline 5 Apr 2025 | 1 articles | Viewed by 2147 | Submission Open

Keywords: Alzheimer’ s disease; pharmacotherapy; therapeutic editing tools; repurposing existing therapeutics; multi-target-directed ligands; preclinical studies; neurodegeneration; drug development; neuroprotection; cannabinoid-based pharmaceuticals; single-molecule drugs or whole-plant extracts of Cannabis sativa L.

(This special issue belongs to the Section Pharmacology)

Membrane Transporters in Drug Development: Recent Advances

edited by

Balázs Sarkadi

submission deadline 5 Apr 2025 | 1 articles | Viewed by 1210 | Submission Open

Keywords: transporters affecting drug ADME-tox; ABC drug transporters; SLC drug transporters; transporters in anticancer drug development; transporters in drug-drug interactions; regulatory issues in transporter-drug interactions; transporters in drug-induced organ damage.

(This special issue belongs to the Section Pharmacology)

The Discovery and Development of Drug Ingredients from Food Sources

edited by

Justyna Żwawiak

and Dorota Olender

submission deadline 5 Apr 2025 | Viewed by 64 | Submission Open

Keywords: natural compounds; food; antioxidants; biological activity of natural substances; the influence of food on health

(This special issue belongs to the Section Natural Products)

Blood–Brain-Barrier-Penetrating Therapeutics Targeting Intrinsically Disordered Proteins in Neurodegenerative Diseases

edited by Chih Hung Lo

submission deadline 10 Apr 2025 | Viewed by 112 | Submission Open

Keywords: drug discovery; small molecules; pharmacological analysis; biosensor engineering; high-throughput screening; nanomedicine; blood– brain barrier; intrinsically disordered proteins; neuroinflammation; neurodegeneration

(This special issue belongs to the Section Pharmaceutical Technology)

The Role of Phytochemicals in Aging and Aging-Related Diseases

edited by

Giovanni Scapagnini

Sergio Davinelli

and

Alessandro Medoro

submission deadline 15 Apr 2025 | 3 articles | Viewed by 6225 | Submission Open

Keywords: phytochemicals; plant-based diet; dietary supplementation; pharma-nutrition; aging; aging-related diseases; prevention

(This special issue belongs to the Section Natural Products)

New Insights of Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitors in Biomedical Applications

edited by

Afif Nakhleh

, Bshara Mansour and Naim Shehadeh

submission deadline 15 Apr 2025 | Viewed by 177 | Submission Open

Keywords: SGLT2 Inhibitors; cardiovascular protection; renal health; metabolic benefits

(This special issue belongs to the Section Pharmacology)

Natural-Based Skincare Solutions

edited by

Célia Cabral

submission deadline 15 Apr 2025 | Viewed by 81 | Submission Open

Keywords: natural products; skincare; cosmetics; bioactive compounds; in vitro assays; in vivo assays; innovative skin formulations; handmade cosmetics

(This special issue belongs to the Section Natural Products)

Pharmacotherapy for Neuropathic Pain

edited by Vittoria Borgonetti and

Nicoletta Galeotti

submission deadline 20 Apr 2025 | 1 articles | Viewed by 2048 | Submission Open

Keywords: neuropathic pain; neuroinflammation; pharmacology; microglia; astrocytes; allodynia; hyperalgesia; personalized therapy; chronic pain; sex differences

(This special issue belongs to the Section Pharmacology)

Peptide Synthesis and Drug Development: Exploring Progress and Potential

edited by

Othman Al Musaimi

, Da’san M.M. Jaradat and Vera D'Aloisio

submission deadline 20 Apr 2025 | Viewed by 475 | Submission Open

Keywords: peptides; enzymatic degradation; drug discovery; formulation; draggability

(This special issue belongs to the Section Biopharmaceuticals)

Therapeutic Methods Against Acute and Chronic Diseases and Oxidative Stress

edited by

Yanka Karamalakova

submission deadline 20 Apr 2025 | Viewed by 89 | Submission Open

Keywords: natural antioxidant; synthetic agents; acute diseases; chronic diseases; oxidative stress

(This special issue belongs to the Section Medicinal Chemistry)

Promising Natural Products in New Drug Design and Therapy

edited by

Mohammad S. Mubarak

submission deadline 20 Apr 2025 | Viewed by 71 | Submission Open

Keywords: natural products; cancer; curcumin; flavonoids; drug delivery; nanotechnology; drug targeting; biological activities; medical applications; food applications; drug discovery; mechanisms of action

(This special issue belongs to the Section Natural Products)

Pluripotent Stem Cell for Novel Drug Discovery

edited by Kevin G. Chen

submission deadline 22 Apr 2025 | Viewed by 318 | Submission Open

Keywords: Pluripotent stem cells; disease modeling; 2D-monolayer culture; 3D tissues; Organoids; drug discovery; drug development

(This special issue belongs to the Section Biopharmaceuticals)

Natural Products for Therapeutic Potential

edited by

Xavier Siwe Noundou

submission deadline 22 Apr 2025 | Viewed by 124 | Submission Open

Keywords: natural products chemistry; therapeutic potential; medicinal plants; marine organisms; microorganisms; bioactive compounds; natural products inspired compounds; biological activities; computational chemistry

(This special issue belongs to the Section Natural Products)

Use of Encapsulating Polymers of Active Compounds in the Pharmaceutical Industry

edited by Alba Adriana Vallejo-Cardona, Inocencio Higuera-Ciapara and

Janna Douda

submission deadline 22 Apr 2025 | Viewed by 60 | Submission Open

Keywords: polymer; drug delivery; active compounds; encapsulation; pharmaceutical industry; natural polymers; synthetic polymers

(This special issue belongs to the Section Pharmaceutical Technology)

Application of Supercritical Fluids in Pharmaceutical Science

edited by

Cecília I. A. V. Santos

submission deadline 23 Apr 2025 | Viewed by 78 | Submission Open

Keywords: supercritical fluids; scCO2; drug formulation; bioavailability; green chemistry; drug delivery systems; nanoparticle encapsulation; bioactive compound extraction; pharmaceutical purification; controlled release; sustainable pharmaceutical processes

(This special issue belongs to the Section Pharmaceutical Technology)

Medicinal Potential of Cannabidiol and New Structural Analogs

edited by

Patricia Fernandes

submission deadline 23 Apr 2025 | Viewed by 64 | Submission Open

Keywords: cancer; inflammation; pain; analgesia; cannabidiol; parkinson disease; huntington disease; alzheimer disease

(This special issue belongs to the Section Medicinal Chemistry)

Drug Candidates for Allergic Diseases

edited by

Luis Manuel Teran

submission deadline 25 Apr 2025 | 8 articles | Viewed by 20846 | Submission Open

Keywords: allergic disease; asthma; CRSwNP; atopic dermatitis; biologicals; chronic urticaria; pharmacology; novel drugs

(This special issue belongs to the Section Pharmacology)

Plant-Derived Nanotherapeutics and Nanocarriers: Recent Progress and Future Directions

edited by

Estefânia V.R. Campos

and

Jhones Luiz De Oliveira

submission deadline 25 Apr 2025 | 7 articles | Viewed by 20280 | Submission Open

Keywords: plant-based nanomaterials; green nanomaterials; drug delivery; natural nanotherapeutics; pharmaceutical nanoformulations; biogenic synthesis; phytonanotechnology

(This special issue belongs to the Section Pharmaceutical Technology)

Pyrazole and Thiazole Derivatives in Medicinal Chemistry

edited by

Dimitris Matiadis

Antonella Messore

and

Nicolas Primas

submission deadline 25 Apr 2025 | 7 articles | Viewed by 9648 | Submission Open

(This special issue belongs to the Section Medicinal Chemistry)

Bioactive Compounds and Their Optimized Structural Derivatives of Natural Products

edited by Yanhua Fan and Shuzhen Mu

submission deadline 25 Apr 2025 | 4 articles | Viewed by 6560 | Submission Open

Keywords: natural products; bioactive compounds and their derivatives; isolation and purification; synthesis; structural modification or optimization; biological evaluation; mechanistic investigations; an evaluation of ADMET properties

(This special issue belongs to the Section Natural Products)

Bioactive Compounds From Plants and Their Therapeutic Applications in Lifestyle-Related Diseases

edited by

Syota Kagawa

and

Agnieszka Ludwiczuk

submission deadline 25 Apr 2025 | 3 articles | Viewed by 4446 | Submission Open

Keywords: natural compounds; lifestyle-related diseases; pharmacology; molecular mechanisms; clinical applications

(This special issue belongs to the Section Natural Products)

Evaluation of the Antitumor Mechanism of Armed Antibodies: 2nd Edition

edited by

Yoshikatsu Koga

Hiroki Takashima

and

Ryo Tsumura

submission deadline 25 Apr 2025 | 3 articles | Viewed by 4420 | Submission Open

Keywords: antibody drug conjugate (ADC); photoimmunotherapy (PIT); radioimmunotherapy (RIT); antibody; conjugated nanoparticle; bispecific antibody; CAR-T cell therapy

(This special issue belongs to the Section Biopharmaceuticals)

Oncolytic Viruses: New Cancer Immunotherapy Drugs

edited by Nikolas T. Martin

submission deadline 25 Apr 2025 | 2 articles | Viewed by 4214 | Submission Open

(This special issue belongs to the Section Pharmacology)

Design and Synthesis of Small Molecule Kinase Inhibitors

edited by

Camilla Pecoraro

and

Daniela Carbone

submission deadline 25 Apr 2025 | 2 articles | Viewed by 3900 | Submission Open

Keywords: protein kinases; cancer; small molecule kinase inhibitors; heterocyclic compounds; cancer resistance; targeted therapy; cancer-altered pathway; genetic mutations; FDA-approved kinase inhibitors; kinase inhibitors combinations

(This special issue belongs to the Section Medicinal Chemistry)

Solubilization and Controlled Release Strategy of Poorly Water-Soluble Drugs 2024

edited by

María Ángeles Peña Fernández

submission deadline 25 Apr 2025 | 3 articles | Viewed by 3384 | Submission Open

Keywords: drug formulation; solubilization; controlled release systems; solubility; poor water-soluble drugs

(This special issue belongs to the Section Pharmaceutical Technology)

The 20th Anniversary of Pharmaceuticals: Advances in Peptide Drug Design and Development: From Sequences to Drug Candidates

edited by Juliana C. C. Dallagnol and David Chatenet

submission deadline 25 Apr 2025 | 1 articles | Viewed by 3181 | Submission Open

Keywords: peptide-based drugs; drug design; therapeutic peptides; peptide synthesis; structure– activity relationship; peptide drug delivery; bioavailability; formulation strategies; peptide therapeutics

(This special issue belongs to the Section Biopharmaceuticals)

Discovery of Novel Antidepressants and Anxiolytics

edited by James Oluwagbamigbe Fajemiroye and Gunnar P. H. Dietz

submission deadline 25 Apr 2025 | 2 articles | Viewed by 2313 | Submission Open

Keywords: biomarkers; depression; anxiety; anxiolytics; antidepressants; preclinical or clinical overview; experimental data; adverse effects; pharmacotherapy options; novel drugs

(This special issue belongs to the Section Pharmacology)

Synthetic Inhibitors of Nucleoside Monophosphate-Kinases

edited by

Mihaela Ileana Ionescu

Ovidiu Oniga

and

Cristina Nastasă

submission deadline 25 Apr 2025 | 1 articles | Viewed by 2244 | Submission Open

Keywords: nucleoside monophosphate-kinases; adenylate kinase; urydilate kinase; tymidilate kinase; guanilate kinase; cytidilate kinase; natural inhibitors; enzymatic activity; drug design; structural studies

(This special issue belongs to the Section Medicinal Chemistry)

In Vivo Nuclear Molecular Imaging in Drug Development and Pharmacological Research: New Advances

edited by Haitao Wu and

Noriko Sato

submission deadline 25 Apr 2025 | 1 articles | Viewed by 1492 | Submission Open

Keywords: in vivo nuclear imaging; biomarker imaging; molecular imaging; PET; SPECT; pharmacokinetics; personalized medicine; drug development; molecular pathway

(This special issue belongs to the Section Radiopharmaceutical Sciences)

Drug Treatment of Thyroid Cancer

edited by

Cristina Alina Silaghi

Carmen Emanuela Georgescu

Horaţiu Silaghi

and

Cristina Pop

submission deadline 25 Apr 2025 | Viewed by 653 | Submission Open

Keywords: differentiated thyroid cancer; medullary thyroid cancer; anaplastic thyroid carcinoma; advanced/metastatic thyroid cancer; refractory thyroid cancer; targeted therapy in thyroid cancer; tyrosine kinase inhibitors; immune checkpoint inhibitors; redifferentiation treatment; drug resistance

Production, Development and Theranostic Applications of Radiopharmaceuticals for Nuclear Medicine

edited by Vlad Ghizdovat, Cipriana Stefanescu and Cécile Philippe

submission deadline 25 Apr 2025 | Viewed by 332 | Submission Open

Keywords: theranostic; radiopharmaceuticals; nuclear medicine; alpha-emitting radioisotopes; beta-emitting radioisotopes; gamma-emitting radioisotopes

(This special issue belongs to the Section Radiopharmaceutical Sciences)

Ion Channels as Pharmacological Targets in Cancer

edited by

Concetta Altamura

Ilaria Saltarella

and

Ester Pagano

submission deadline 25 Apr 2025 | Viewed by 246 | Submission Open

Keywords: ion channels; cancer; cancer pharmacology; target therapies; personalized therapy; chemoresistance; oncology; channelopathies

(This special issue belongs to the Section Pharmacology)

Therapeutic Drug Monitoring and Adverse Drug Reactions: 2nd Edition

edited by Engi Abd El Hady Algharably and Ursula Gundert-Remy

submission deadline 25 Apr 2025 | Viewed by 96 | Submission Open

Keywords: therapeutic drug monitoring; adverse drug reactions; pharmacokinetics; personalized medicine; medication safety; pharmacogenomics; medication review; pharmacokinetic modelling

(This special issue belongs to the Section Pharmacology)

New Development in Pharmacotherapy of Kidney Diseases

edited by Chihchao Yang

submission deadline 25 Apr 2025 | Viewed by 72 | Submission Open

Keywords: chronic kidney disease (CKD); acute kidney injury (AKI); pharmacotherapy; cardiovascular protection; kidney protection; bone health; endocrine function; gut health; metabolism; neuromuscular function; nutrition; symptom management; sodium-glucose cotransporter-2 (SGLT-2) inhibitors; glucagon-like peptide-1 (GLP-1) receptor agonists; non-steroidal mineralocorticoid receptor antagonists (MRA); endothelin receptor antagonists; anemia management; electrolyte abnormalities; dialysis; nephrotoxicity; drug interactions; uremic toxin; clinical trials; innovative therapies; protein-energy wasting; chronic kidney disease and bone mineral disease; inflammation; oxidation; diabetes; hypertension; obesity; hyperlipidemia; pruritus; osteoporosis; fracture; sarcopenia; protein-energy wasting

(This special issue belongs to the Section Pharmacology)

Pharmacotherapy of Dyslipidemias, 2nd Edition

edited by

Daniel Dias Rufino Arcanjo

and

Maria do Carmo de Carvalho e Martins

submission deadline 25 Apr 2025 | Viewed by 51 | Submission Open

Keywords: atherosclerosis; dyslipidemia; endothelial dysfunction; fatty acids; high-fat diet; hyperlipidemia; hypertriglyceridemia; polyunsaturated fatty acids; PUFA; statins

(This special issue belongs to the Section Medicinal Chemistry)

Challenges and Emerging Trends in Photopharmacology

edited by Oleksandra Tiapko and Bernadett Bacsa

submission deadline 25 Apr 2025 | Viewed by 46 | Submission Open

Keywords: photopharmacology; ion channels; receptors; protein– ligand interactions; precision medicine; optogenetics

(This special issue belongs to the Section Pharmacology)

Application of Magnetic Resonance Imaging (MRI) in Diagnosis and Treatment of Mental Diseases, 2nd Edition

edited by Deborah A. Yurgelun-Todd, Douglas Kondo, Nicolas A Nunez, Perry Franklin Renshaw and Dost Öngür

submission deadline 25 Apr 2025 | Viewed by 24 | Submission Open

Keywords: neuroimaging; biomarkers; 1H-MRS; 31P-MRS; brain spectroscopy; mood disorders

(This special issue belongs to the Section Pharmaceutical Technology)

Displaying special issue 251-300 on page 6 of 8.

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