Pharmaceuticals

Targeting the Proteostasis Network: From Fundamental Mechanisms to Therapeutic Innovation

edited by Jianhui Li and

submission deadline 30 Sep 2026 | Viewed by 149 | Submission Open

Keywords: ubiquitin– proteasome system; autophagy; protein homeostasis; targeted protein degradation and stabilization; protein quality control; post-translational modifications; cell signaling

(This special issue belongs to the Section Biopharmaceuticals)

Management and Treatment of Cardiometabolic Disorders Across the Lifespan

edited by Pasquale Mone,

Maria Luisa D’Onghia

and Luigi Simone Aversa

submission deadline 5 Oct 2026 | Viewed by 253 | Submission Open

Keywords: cardiometabolic disorders; frailty; diabetes; prediabetes; insulin resistance; hypertension; atherosclerotic cardiovascular disease; obesity; metabolic syndrome; plastic surgery

(This special issue belongs to the Section Pharmacology)

Melatonin Applications in Pharmaceutical Science

edited by

Javier Menéndez-Menéndez

submission deadline 10 Oct 2026 | Viewed by 466 | Submission Open

Keywords: melatonin; pineal gland; epigenetics; pharmacology; physiology; immunology; pharmaceutics; novel therapies; cancer

(This special issue belongs to the Section Pharmacology)

Chronic Inflammation: Molecular Mechanisms and Precision Biomarkers

edited by

Cristina Stefania Dumitru

and Raul Patrascu

submission deadline 10 Oct 2026 | Viewed by 237 | Submission Open

Keywords: chronic inflammation; molecular mechanisms; precision biomarkers; immunopathology; cytokines; tumor microenvironment; head and neck diseases; personalized medicine; inflammatory pathways; translational research

(This special issue belongs to the Section Medicinal Chemistry)

Natural Pharmacons: Biologically Active Plant-Based Pharmaceuticals—4th Edition

edited by

Dejan Stojković

and

Marina Soković

submission deadline 15 Oct 2026 | 10 articles | Viewed by 16933 | Submission Open

Keywords: chemical characterization of natural preparations; therapeutic potential of natural matrices in cardiovascular diseases; diabetes; cancer; and neurodegenerative diseases; antimicrobial activity; antioxidant activity; anti-enzymatic activity; anti-inflammatory activity; mechanism of pharmacological actions; structure– activity relationship studies

(This special issue belongs to the Section Natural Products)

Allosteric Drug Design in the AI Era

edited by Lydia Siragusa and

Antonella Ciancetta

submission deadline 15 Oct 2026 | Viewed by 472 | Submission Open

Keywords: allosteric modulation; artificial intelligence in drug discovery; computational pharmacology; allosteric sites prediction; structure-based drug design

(This special issue belongs to the Section AI in Drug Development)

Advanced (Bio-)Nanomaterials for Biomedicine: Bridging Design, Fabrication, and Biological Interactions

edited by

Nataniel Białas

and

Piotr Golec

submission deadline 16 Oct 2026 | Viewed by 95 | Submission Open

Keywords: advanced nanomaterials; nanomaterial design and synthesis; nano– bio interactions; bioimaging; gene delivery and silencing; antimicrobial strategies; bacterial biofilms; advanced translational models

(This special issue belongs to the Section Pharmaceutical Technology)

New Advances in Antiarrhythmic Drugs

edited by

Norbert Szentandrássy

submission deadline 20 Oct 2026 | 7 articles | Viewed by 23554 | Submission Open

Keywords: antiarrhythmic drugs; ion channel blockers; cardiac action potential; sudden cardiac death; cardiac arrhythmia; proarrhythmic action

(This special issue belongs to the Section Pharmacology)

Advancements in Radiopharmaceutical Theranostics

edited by

Aiko Yamaguchi

, Shilpa Sharma and

Ryan Patrick Coll

submission deadline 20 Oct 2026 | 3 articles | Viewed by 3161 | Submission Open

Keywords: radiopharmaceuticals; radiotheranostics; emerging radionuclides; radiometals; image-guided dosimetry; alpha-emitters; PET; SPECT; radioligand therapy; targeted radionuclide therapy

(This special issue belongs to the Section Radiopharmaceutical Sciences)

Next-Generation Targeted Therapy: vNARs, VHH, and Peptides as Drug Carriers and Intracellular Neutralizing Agents

edited by

Tanya Camacho-Villegas

and

Mirna Burciaga-Flores

submission deadline 20 Oct 2026 | 1 articles | Viewed by 1156 | Submission Open

Keywords: vNAR; VHH; peptides; drug delivery; intrabodies; payload; nanotechnology; immunotoxins; phage display; biopanning; single domain antibody; neutralizing agents; intracellular targeting

(This special issue belongs to the Section Pharmacology)

Natural Products in Gut Microbiome Modulation: Mechanisms and Clinical Applications

edited by

Rebeca André

and

Patrícia Rijo

submission deadline 20 Oct 2026 | Viewed by 169 | Submission Open

Keywords: gut microbiome modulation; natural bioactive compounds; microbiome-targeted therapeutics; gut microbiome; human health

(This special issue belongs to the Section Natural Products)

Pharmacotherapy of Thromboembolism

edited by

Matej Samoš

,

Tomáš Bolek

and

Marián Mokáň

submission deadline 25 Oct 2026 | 8 articles | Viewed by 29875 | Submission Open

Keywords: activated factor XI inhibitors; platelet glycoprotein VI antagonists; PAR4 antagonists; PI3K inhibitorslong-term anticoagulation; antiplatelet therapy; novel antithrombotic drugs; anticoagulation-related bleeding; post-vascular procedure-related thrombosis

(This special issue belongs to the Section Pharmacology)

Pharmacovigilance Insights: Addressing Drug Misuse and Enhancing Drug Safety

edited by

Cristina Sofia De Jesus Monteiro

and

Samuel Martins Silvestre

submission deadline 25 Oct 2026 | 10 articles | Viewed by 17555 | Submission Open

Keywords: adverse drug reaction; pharmacovigilance; drug safety; signal detection; risk management

(This special issue belongs to the Section Pharmacology)

Research on Diagnosis, Treatment and Related Microbiota in Gastrointestinal Diseases

edited by

Edoardo V. Savarino

and Brigida Barberio

submission deadline 25 Oct 2026 | 5 articles | Viewed by 7792 | Submission Open

Keywords: gut microbiota; inflammatory bowel disease; eosinophilic esophagitis; primary sclerosing cholangitis; metabolic-associated steatotic liver disease; immune checkpoint inhibitor colitis; dysbiosis; prebiotics; probiotics

(This special issue belongs to the Section Medicinal Chemistry)

Tumor Immunopharmacology, 2nd Edition

edited by

Marco A. Velasco-Velázquez

and

Nohemí Salinas-Jazmín

submission deadline 25 Oct 2026 | 3 articles | Viewed by 5189 | Submission Open

Keywords: immunotherapy; immunomodulation; drug development; cytokine receptor antagonist; T-cell based therapies; therapeutic antibodies; drug delivery; cancer vaccine; immunoresistance; tumor-infiltrating lymphocytes (TILs); immune escape; immune checkpoint inhibitors; cytokine-based therapies; small molecule immunomodulators; combination therapy; precision oncology; tumor mutational burden (TMB); antibody-dependent cellular cytotoxicity (ADCC ); complement-dependent cytotoxicity (CDC); myeloid-derived suppressor cells (MDSCs)

(This special issue belongs to the Section Pharmacology)

Novel Therapeutic Targets in the Cardiovascular Treatment Landscape

edited by Weida Wu and

Nikolaos Kadoglou

submission deadline 25 Oct 2026 | 3 articles | Viewed by 2801 | Submission Open

Keywords: cardiovascular disease; novel therapeutic targets; lipid metabolism; cardiac fibrosis and remodeling; inflammation and immune modulation; Lp(a); heart failure; RNA therapeutics; precision cardiology; cardiomyopathy

(This special issue belongs to the Section Pharmacology)

The Role of Phytochemicals in Aging and Aging-Related Diseases, 2nd Edition

edited by

Giovanni Scapagnini

,

Sergio Davinelli

and

Alessandro Medoro

submission deadline 25 Oct 2026 | 3 articles | Viewed by 2658 | Submission Open

Keywords: phytochemicals; plant-based diet; dietary supplementation; pharma-nutrition; aging; aging-related diseases; prevention

(This special issue belongs to the Section Natural Products)

Epithelial Plasticity and Therapy Resistance in Cancer

edited by

Naisana Seyedasli

submission deadline 25 Oct 2026 | 2 articles | Viewed by 2474 | Submission Open

Keywords: cancer stem cells; epithelial– mesenchymal transition; epithelial reprogramming; resistance; drug targets; resistance mechanisms; biomarker discovery

(This special issue belongs to the Section Pharmacology)

Synthesis, In Silico Prediction and Antitumor Activity of Nitrogen Heterocycle-Based Drug Development

edited by Jamerson F. De Oliveira and Paulo André Teixeira de Moraes Gomes

submission deadline 25 Oct 2026 | 2 articles | Viewed by 1981 | Submission Open

Keywords: privileged structures; nitrogen heterocycles; ADMET prediction; cancer biological target; molecular dynamic; computational studies; antitumor activity; in vitro and in vivo studies; SAR of lead compounds; molecular hybridization

(This special issue belongs to the Section Medicinal Chemistry)

Next-Generation Approaches for Cartilage Regeneration

edited by

Valeria Graceffa

and Liam Morris

submission deadline 25 Oct 2026 | 1 articles | Viewed by 1781 | Submission Open

Keywords: cartilage regeneration; cartilage engineering; bioactive molecules (peptides/proteins/nucleic acids); biomaterials (therapeutic delivery); gene engineering (biopharmaceutical applications); chondrogenic signaling pathways; preclinical/clinical evaluation (cartilage repair); osteoarthritis (therapeutic interventions); therapeutic targets (cartilage repair); translational regenerative medicine

(This special issue belongs to the Section Biopharmaceuticals)

Development of Specific Dosage Form: Wound Dressing, 2nd Edition

edited by

Mihaela Violeta Ghica

,

Madalina Georgiana Albu Kaya

,

Lacramioara Popa

and Cristina Elena Dinu-Pirvu

submission deadline 25 Oct 2026 | 1 articles | Viewed by 1405 | Submission Open

Keywords: skin lesion; wound healing; wound dressing; regenerative medicine; biomaterials; smart biopolymers; therapeutic system; controlled delivery system; scaffolds; biocompatibility

(This special issue belongs to the Section Pharmaceutical Technology)

Natural Products for the Treatment of Prostate Cancer

edited by

Maria Loreta Libero

and

Annalisa Chiavaroli

submission deadline 25 Oct 2026 | 1 articles | Viewed by 1070 | Submission Open

Keywords: prostate cancer; natural compounds; plants; urinary tract infections; supplements; signaling pathways

(This special issue belongs to the Section Natural Products)

Advances in and Perspectives on Oral Drug Delivery

edited by

Laxman Subedi

and

Mohammad Imran

submission deadline 25 Oct 2026 | Viewed by 371 | Submission Open

Keywords: enhanced drug delivery; oral route; oral peptide delivery; 3D printing; continuous manufacturing; PBPK modeling; nanocarriers; translational pharmaceutics; low aqueous solubility and low permeability; enhanced oral bioavailability; transporter targeting; emerging materials and excipients in oral delivery; dosage form transition of already marketed drugs; examining herbal or traditional drugs oral delivery; sustained release; nanotechnology; application of cellular components such as exosomes or vesicles for oral delivery; in silico docking for PBPK; nanocarriers; lipid-based formulations; self-emulsifying drug delivery systems (SEDDS); solid dispersions; mucoadhesive systems

(This special issue belongs to the Section Pharmaceutical Technology)

Quality Control and Standardization of Plant-Based Pharmaceuticals

edited by

Maryam Malmir

and

Emran Habibi

submission deadline 25 Oct 2026 | Viewed by 280 | Submission Open

Keywords: quality control and standardization of plant-based products; authentication of medicinal plants; phytochemical characterization; secondary marker metabolites; pharmacological validation; safety and toxicological assessment; pharmaceutical formulation; evidence-based herbal medicine; ethnopharmacology; regulatory aspects of herbal medicines; reproducibility in natural products research

(This special issue belongs to the Section Natural Products)

Application and Translational Research of Lanthanide/Nanomaterial-Conjugated Photosensitizers in Photodynamic Therapy

edited by

Céline Frochot

submission deadline 25 Oct 2026 | Viewed by 248 | Submission Open

Keywords: lanthanide-based nanomaterials; nanomaterial-conjugated photosensitizers; photodynamic therapy (PDT); targeted delivery; upconversion luminescence; preclinical evaluation; translational research; biocompatibility

(This special issue belongs to the Section Pharmaceutical Technology)

Plant Extracts Regulating Oxidative Stress and Metabolism: Drug Discovery and Repurposing

edited by

Paulina Ormazabal

and

Roberto Bravo-Sagua

submission deadline 25 Oct 2026 | Viewed by 166 | Submission Open

Keywords: plant extracts; natural compounds; oxidative stress; redox signaling; metabolic regulation; insulin resistance; mitochondrial dysfunction; inflammation; neurodegeneration

(This special issue belongs to the Section Natural Products)

Advances in Antiparasitic Drug Research: 2nd Edition

edited by

Andre Aires

and

Maria Cristiano

submission deadline 25 Oct 2026 | Viewed by 118 | Submission Open

Keywords: antiparasitic drug; novel drug targets; parasite resistance; drug efficacy; parasite genetics

(This special issue belongs to the Section Pharmacology)

Development of Novel Radiopharmaceuticals for SPECT and PET Imaging, 2nd Edition

edited by

Bianca Gutfilen

submission deadline 25 Oct 2026 | Viewed by 17 | Submission Open

Keywords: oncology; theranostics; inflammation/infection diagnosis; autoimmune diseases; neurodegenerative diseases; cardiovascular diseases

(This special issue belongs to the Section Radiopharmaceutical Sciences)

Advancements in Cardiovascular and Antidiabetic Drug Therapy, 2nd Edition

edited by

Alfredo Caturano

submission deadline 27 Oct 2026 | 17 articles | Viewed by 37526 | Submission Open

Keywords: cardiovascular diseases; antidiabetic drugs; pharmacological interventions; sodium– glucose cotransporter 2 inhibitors; PCSK9 inhibitors; obeticholic acid; lipid-lowering agents; heart failure treatment; diabetes management; drug therapy innovations

(This special issue belongs to the Section Pharmacology)

Advances in Biotechnological Formulations for Skin Disorders: Delivery Strategies and Biocompatibility

edited by Marcel Henrique Marcondes Sari,

Raul Edison Luna Lazo

and

Luana Mota Ferreira

submission deadline 27 Oct 2026 | 4 articles | Viewed by 13913 | Submission Open

Keywords: skin disorders; biotechnological formulations; nanocarriers; probiotic-based formulations; natural products; polysaccharides; skin delivery systems; bioactive compounds; antioxidant and anti-inflammatory effects; wound healing; safety and efficacy in skin therapies

(This special issue belongs to the Section Pharmaceutical Technology)

Bioactive Natural Extracts: Advances in Pharmacological and Therapeutic Research

edited by

Gabriela-Maria Baci

and

Victorița Bonta

submission deadline 30 Oct 2026 | 8 articles | Viewed by 6982 | Submission Open

Keywords: bioactive compounds; natural extracts; pharmacological activity; drug discovery; plant-derived compounds

(This special issue belongs to the Section Natural Products)

Therapeutic Potential of Natural Extracts in Cancer Prevention and Treatment

edited by

Zlatina Gospodinova

and

Michael Danilenko

submission deadline 30 Oct 2026 | 2 articles | Viewed by 3710 | Submission Open

Keywords: natural products; anticancer therapeutic potential; cancer chemoprevention; mechanism of action and molecular targets; preclinical and clinical studies

(This special issue belongs to the Section Natural Products)

Innovative Drug Delivery Systems for Enhanced Dissolution and Bioavailability

edited by Marival Bermejo,

Paloma Marina De la Torre-Iglesias

and Covadonga Álvarez-Álvarez

submission deadline 30 Oct 2026 | 2 articles | Viewed by 2436 | Submission Open

Keywords: drug dissolution enhancement; oral bioavailability improvement; poorly soluble drugs; solid dispersions; nanoparticle drug delivery; amorphous formulations; 3D printing in pharmaceuticals; advanced drug-polymer systems; advanced excipients for solubility enhancement; controlled drug release

(This special issue belongs to the Section Pharmaceutical Technology)

Synthesis and Anticancer Activity of Biologically Active Heterocyclic Compounds

edited by

Birutė Grybaitė

and Rita Vaickelionienė

submission deadline 30 Oct 2026 | 2 articles | Viewed by 2204 | Submission Open

Keywords: heterocyclic compounds; five- or six-membered heterocycles; oxygen- and nitrogen-based heterocycles; sulfur- and nitrogen-based heterocycles; azoles; small molecules; anticancer activity; cell lines; cytotoxicity

(This special issue belongs to the Section Medicinal Chemistry)

Kynurenine Pathway: A Novel Therapeutic Opportunity—2nd Edition

edited by

Verónica Pérez de la Cruz

,

Tonali Blanco-Ayala

and

Daniela Ramírez-Ortega

submission deadline 30 Oct 2026 | 1 articles | Viewed by 1445 | Submission Open

Keywords: tryptophan catabolism; redox modulation; kynurenines; immunoregulation

(This special issue belongs to the Section Pharmacology)

Targeted Radiopharmaceutical Therapies: Cutting-Edge Advances

edited by Noeen Malik

submission deadline 30 Oct 2026 | Viewed by 316 | Submission Open

Keywords: targeted radiopharmaceutical therapies (TRT); radiopharmaceuticals; radionuclide therapy; molecular radiotherapy; radioisotopes; radiochemistry; isotope production; radionuclide delivery; preclinical evaluation; clinical translation

(This special issue belongs to the Section Radiopharmaceutical Sciences)

Improving Pharmaceutical Formulation and Stability In Silico Methods

edited by

Samuel O. Kyeremateng

submission deadline 30 Oct 2026 | Viewed by 123 | Submission Open

Keywords: in silico modeling; drugs and formulations; molecular dynamics; quantum mechanics; discrete element method; computational fluid dynamics; formulation design; dissolution; stability; manufacturing

(This special issue belongs to the Section Pharmaceutical Technology)

Adjuvant Therapies for Cancer Treatment: 2nd Edition

edited by

Fuyi Wang

submission deadline 31 Oct 2026 | 12 articles | Viewed by 109155 | Submission Open

Keywords: drug repurposing; combined therapies; new compounds; drug resistance; chemosensitization; antitumoral strategies

(This special issue belongs to the Section Pharmacology)

NeuroImmunoEndocrinology

edited by

Lenin Pavón

,

Daniel Ortuño-Sahagún

,

Gilberto Perez-Sanchez

and Oscar Adelmo Bottasso

submission deadline 31 Oct 2026 | 11 articles | Viewed by 62404 | Submission Open

Keywords: cytokines; neurotransmitters; hormones; infections; antibiotics; antidepressants; antipsychotics; drugs; stress; depression; schizophrenia; immunomodulation

(This special issue belongs to the Section Pharmacology)

Treatment and Molecular Mechanisms of Depression

edited by

Zuleide Maria Ignácio

and Ricieri Mocelin

submission deadline 31 Oct 2026 | 1 articles | Viewed by 5641 | Submission Open

Keywords: major depressive disorder; molecular mechanisms; neurotransmitters; epigenetic; genetic polymorphisms; inflammation; neuroinflammation; pharmacological strategies; drugs; intracellular signaling

(This special issue belongs to the Section Medicinal Chemistry)

Cholinergic Modulation, Anticholinergic Burden, and Neuroprotection: Mechanisms to Therapeutics

edited by

Ion Brinza

and

Lucian Hritcu

submission deadline 31 Oct 2026 | 3 articles | Viewed by 4950 | Submission Open

Keywords: scopolamine; anticholinergic burden; cholinergic modulation; cognitive impairment; neuroinflammation; oxidative stress; BBB/drug delivery; PK/PD; biomarkers; network pharmacology; flavonoids/polyphenols; zebrafish models; translational neuroscience; deprescribing

(This special issue belongs to the Section Pharmacology)

Polymers, Nanoparticles and Hydrogels for Drug Delivery: Strategies and Applications

edited by Mónica de la Luz Corea Téllez, Marlon Rojas López,

Lucia Tellez-Jurado

and Rogelio Jiménez-Juárez

submission deadline 31 Oct 2026 | 2 articles | Viewed by 2967 | Submission Open

Keywords: drug delivery; medical applications; hydrogels; polymers; nanoparticles; drug delivery system; multi-stimuli-responsive materials; nanocomposites; biofilms; biomarkers

(This special issue belongs to the Section Pharmaceutical Technology)

Exploring Natural Products with Antioxidant and Anticancer Properties, 2nd Edition

edited by

Sikiru Olaitan Balogun

and

Edson Lucas Dos Santos

submission deadline 31 Oct 2026 | 3 articles | Viewed by 2890 | Submission Open

Keywords: antioxidant; anticancer; neoplasms; natural products; cytotoxicity

(This special issue belongs to the Section Natural Products)

Pharmacological Treatments for Parasitic Diseases

edited by Maria Dichiara and

Giuliana Costanzo

submission deadline 31 Oct 2026 | 3 articles | Viewed by 2112 | Submission Open

Keywords: parasitic diseases; antiparasitic agents; drug resistance; therapeutic strategies; drug discovery; neglected tropical diseases (NTDs); medicinal chemistry; global health

(This special issue belongs to the Section Medicinal Chemistry)

Drug Safety and Risk Management in Clinical Practice: 2nd Edition

edited by Andreea Maria Farcas

submission deadline 31 Oct 2026 | 1 articles | Viewed by 758 | Submission Open

Keywords: drug safety; adverse drug reactions; risk minimization measures; effectiveness of risk minimization measures; drug utilization studies

(This special issue belongs to the Section Pharmacology)

Application of Nuclear Magnetic Resonance (NMR) in Drug Discovery and Development

edited by Vladimir M. Gelev

submission deadline 31 Oct 2026 | Viewed by 440 | Submission Open

Keywords: biomolecular NMR; drug discovery; library screening using NMR; SAR using NMR; fragment-based drug discovery using NMR

(This special issue belongs to the Section Pharmaceutical Technology)

Cholinesterases—Structure, Mechanism, Function and Drug Discovery

edited by

Carmen L. Cardoso

submission deadline 31 Oct 2026 | Viewed by 431 | Submission Open

Keywords: cholinesterases; cholinesterase inhibitors; structure-based design of inhibitors; multi-target ligands; non-cholinergic functions; structure; allosteric sites; mechanism; non-classical functions

(This special issue belongs to the Section Medicinal Chemistry)

Investigating the Therapeutic Potential of Natural Products in Internal Diseases

edited by Roberto Pontarolo and

Raul Edison Luna Lazo

submission deadline 31 Oct 2026 | Viewed by 358 | Submission Open |

Keywords: natural products; internal diseases; cardiovascular diseases; diabetes; autoimmune disorders; gastrointestinal conditions; respiratory illnesses

(This special issue belongs to the Section Natural Products)

Molecular Insights and Clinical Implications in Geriatric Medicine and Drug Development

edited by

Katarzyna Mądra-Gackowska

,

Marcin Gackowski

, Kornelia Kędziora-Kornatowska and

Iga Hołyńska-Iwan

submission deadline 31 Oct 2026 | Viewed by 349 | Submission Open

Keywords: older adults; age-related diseases; biomarkers; drug development; molecular modeling; computer-aided drug design; geriatrics in laboratory medicine; laboratory tests in older patients; malnutrition diagnostics; test results versus a clinical image of an older patient

(This special issue belongs to the Section Pharmacology)

Novel Cannabinoid Receptor Ligands: Discovery, Pharmacology, and Therapeutic Applications

edited by

Rebecca Ferrisi

and

Clementina Manera

submission deadline 31 Oct 2026 | Viewed by 332 | Submission Open

Keywords: cannabinoid receptor modulators; synthetic cannabinoids; allosteric modulation; biased signaling; covalent ligands; PROTACs; cannabinoid probes; inflammation; CNS disorders; cancer

(This special issue belongs to the Section Pharmacology)

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