Pharmaceuticals

Plant Extracts with Biological Activity and Potential Antioxidant Action

edited by Claudia-Crina Toma,

Giancarlo Statti

,

Filomena Conforti

,

Mariangela Marrelli

and Cerasela Elena Gîrd

submission deadline 30 Jul 2026 | 6 articles | Viewed by 7241 | Submission Open

Keywords: phenolic compounds; flavonoids; vegetal growth factors; oxidative stress; plant primary metabolites; plant secondary metabolites; nutraceuticals

(This special issue belongs to the Section Natural Products)

Pharmacology and Toxicology of Opioids, 2nd Edition

edited by

Juliana Faria

, Joana Barbosa and

Ricardo Dinis-Oliveira

submission deadline 31 Jul 2026 | 8 articles | Viewed by 14297 | Submission Open

Keywords: opioid toxicity; opioid pharmacodynamics; opioid pharmacokinetics; opioid pharmacogenetics; prescription opioids; toxicity assays; in vivo; in vitro; abuse; dependence

(This special issue belongs to the Section Pharmacology)

Pharmacological Activities and Therapeutic Potential of Novel Drug Derivatives

edited by

Stoyanka Nikolova

and

Vera Gledacheva

submission deadline 31 Jul 2026 | 2 articles | Viewed by 12793 | Submission Open

Keywords: novel drug derivatives; synthesis; drug design; therapeutic potential; biological activity; pharmacological activity

(This special issue belongs to the Section Pharmacology)

Application of Computer Simulation in Drug Design

edited by

Alessia Bono

and

Antonino Lauria

submission deadline 31 Jul 2026 | 4 articles | Viewed by 6765 | Submission Open

Keywords: in silico; drug design; drug discovery; molecular docking; molecular dynamics simulations; structure-based; ligand-based; virtual screening; drug repurposing

(This special issue belongs to the Section Medicinal Chemistry)

Advances in Hydrazone Compounds with Anticancer Activity

edited by

Boryana Nikolova-Mladenova

and

Mariyana Atanasova

submission deadline 31 Jul 2026 | 2 articles | Viewed by 5112 | Submission Open

Keywords: hydrazones; lipophilicity; logP; anticancer activity; selectivity

(This special issue belongs to the Section Medicinal Chemistry)

Heterocyclic Compounds in Targeted Cancer Therapy: Advances in Medicinal Chemistry and Drug Development

edited by

Gabriele La Monica

and

Annamaria Martorana

submission deadline 31 Jul 2026 | 3 articles | Viewed by 4806 | Submission Open

Keywords: heterocyclic compounds; targeted cancer therapy; medicinal chemistry; structure–activity relationship (SAR); computational drug design; small-molecule therapeutics; synthetic methodologies; bioactive heterocycles; green chemistry in drug discovery; in silico screening

(This special issue belongs to the Section Medicinal Chemistry)

The Nuclear Factor Kappa-B (NF-κB) Pathway as a Target for Drug Discovery

edited by Guozhou Xu

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1847 | Submission Open

Keywords: NF-kappaB; TNFR; TLR; IL1R; receptor adaptor proteins; IRAK; c-IAP; AKT IKK; ubiquitin–proteasome system; inflammatory response

(This special issue belongs to the Section Medicinal Chemistry)

Advanced Nanocarriers for Intranasal Drug Delivery to the Central Nervous System

edited by

Amnon Sintov

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1720 | Submission Open

Keywords: intranasal drug delivery; nano-formulations; brain targeting; central nervous system disorders; neurological diseases; nanomedicine

(This special issue belongs to the Section Pharmaceutical Technology)

Immunomodulatory Drugs for Autoimmune Diseases: Mechanisms, Development and Clinical Translation

edited by Patricia Fanlo-Mateo

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1452 | Submission Open

Keywords: autoimmune diseases; immunomodulatory drugs; biologic therapies; immunosupressants; immunotherapy; drug repurposing

(This special issue belongs to the Section Medicinal Chemistry)

Peptide Synthesis and Drug Development: Exploring Progress and Potential, 2nd Edition

edited by

Othman Al Musaimi

and Vera D'Aloisio

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1441 | Submission Open

Keywords: peptides; enzymatic degradation; drug discovery; formulation; druggability

(This special issue belongs to the Section Biopharmaceuticals)

Supersaturated Formulations in Drug Development: From Solubility Investigations to the Advancement of In Vitro–In Vivo Predictability

edited by Réka Angi,

Tamas Solymosi

, Anna Vincze,

María Peña Fernández

and

Ziyaur Rahman

submission deadline 31 Jul 2026 | Viewed by 427 | Submission Open

Keywords: supersaturation; solubility assessment; dissolution mechanisms; advanced formulations; amorphous solid dispersion; nanoprecipitation; in vitro–in vivo prediction; absorption modelling; phase transitions

(This special issue belongs to the Section Pharmaceutical Technology)

Interdisciplinary Approaches to Preventing and Treating Inflammatory and Oxidative Diseases with Medicinal Plants and Bioactive Compounds

edited by

Lucas Fornari Laurindo

and

Sandra Barbalho

submission deadline 10 Aug 2026 | 4 articles | Viewed by 12426 | Submission Open

Keywords: interdisciplinary studies; inflammation; inflammatory diseases; oxidative stress; oxidative diseases; pro-inflammatory; pro-oxidative; neurodegenerative diseases; cardiovascular diseases; cancer; medicine; rheumatological diseases; endocrinological diseases; gastroenterological diseases; dermatological diseases; pulmonary diseases; dentistry; nutrition; dietetics; therapy; medicinal plants; bioactive compounds; phytochemicals; phytochemistry

(This special issue belongs to the Section Natural Products)

Population Pharmacokinetics and Pharmacogenetics, 2nd Edition

edited by

Seung-Hyun Jeong

submission deadline 10 Aug 2026 | 1 articles | Viewed by 859 | Submission Open

Keywords: pharmacokinetics; pharmacogenetics; precision medicine; population pharmacometrics model; mathematical modeling; dosage regimen; inter-subject variability

(This special issue belongs to the Section Pharmacology)

Recent Strategies for Delivery of Plant-Based Active Ingredients

edited by

Federica De Gaetano

and

Cinzia Anna Ventura

submission deadline 14 Aug 2026 | 2 articles | Viewed by 4977 | Submission Open

Keywords: drug delivery; polymeric nanoparticles; lipid nanosystems; inclusion complexes; polymeric cyclodextrins; protein carriers; inorganic delivery systems; nanostructured carriers; chemical–physical characterization; in vitro/ex vivo/in vivo evaluation

(This special issue belongs to the Section Pharmaceutical Technology)

Nanoparticle-Enabled Combination Therapy in Preclinical Development

edited by Tamiles Caroline Fernandes Pedrosa,

Eduardo Burgarelli Lages

,

Fernanda Karoline Vieira da Silva Torchelsen

and

Raquel Silva Araújo

submission deadline 14 Aug 2026 | Viewed by 303 | Submission Open

Keywords: drug delivery systems; nanoparticles; nanomedicine; drug combinations; drug co-delivery; preclinical; translational drug development

(This special issue belongs to the Section Pharmaceutical Technology)

Application of Zebrafish Model in Pharmacology and Toxicology

edited by

Geonildo Rodrigo Disner

and

Mônica Lopes-Ferreira

submission deadline 15 Aug 2026 | 5 articles | Viewed by 8086 | Submission Open

Keywords: chemical safety assessment; translational research; drug screening; human exposome; environmental contaminants

(This special issue belongs to the Section Pharmacology)

Enzyme Inhibitors: Potential Therapeutic Approaches, 2nd Edition

edited by

Phaedra Eleftheriou

submission deadline 15 Aug 2026 | 1 articles | Viewed by 1941 | Submission Open

Keywords: enzymes; inhibitors; competitive; uncompetitive; non-competitive; drug target; pharmaceutical approach; disease treatment

(This special issue belongs to the Section Medicinal Chemistry)

Advances in the Mechanism of Action and the Therapeutic Role of Phytopharmaceuticals

edited by Maria-Eleni Grafakou and

Jörg Heilmann

submission deadline 20 Aug 2026 | 6 articles | Viewed by 23059 | Submission Open

Keywords: medicinal plants; natural products; phytochemistry; biological activities; mechanism of action; biotransformation; microbiome

(This special issue belongs to the Section Natural Products)

Resveratrol: Pharmacological Mechanisms and Therapeutic Potential as a Natural Product

edited by

Dumitriţa Rugină

and

Roxana Pop

submission deadline 20 Aug 2026 | 1 articles | Viewed by 2471 | Submission Open

Keywords: resveratrol; natural compound pharmacology; therapeutic potential; drug development; biomedical research

(This special issue belongs to the Section Natural Products)

Challenges in the Development of PET and SPECT Radiotracers: Innovative Ideas with Negative Outcomes

edited by Magali Toussaint and Barbara Wenzel

submission deadline 25 Aug 2026 | 8 articles | Viewed by 13695 | Submission Open

Keywords: radiotracer development; positron emission tomography (PET); single-photon emission computed tomography (SPECT); negative results; diagnostic radiotracers; therapeutic radiopharmaceuticals; radiolabeling; automated synthesis and GMP; pre-clinical studies; medicinal chemistry

(This special issue belongs to the Section Radiopharmaceutical Sciences)

Chemotherapeutic and Targeted Drugs in Antitumor Therapy

edited by

Angéla Takács

and

László Kőhidai

submission deadline 25 Aug 2026 | 2 articles | Viewed by 4481 | Submission Open

Keywords: cancer; drug discovery; small-molecule drugs; targeted therapy; combination therapy; synergism; selectivity; immunotherapy; precision medicine

(This special issue belongs to the Section Pharmacology)

Innovative Approaches to GABAergic Drug Discovery: From Molecular Mechanisms to Advanced Therapeutics

edited by

Wojciech Kołodziejczyk

and

Donato Colangelo

submission deadline 25 Aug 2026 | 2 articles | Viewed by 3483 | Submission Open

Keywords: GABAergic signaling; GABA receptors; drug discovery; neurological and psychiatric disorders; ligand design; computational drug development; artificial intelligence in pharmacology; high-throughput screening; targeted drug delivery; controlled release systems

(This special issue belongs to the Section Pharmacology)

Drug Treatment for Epilepsy

edited by Clarissa Fantin Cavarsan

submission deadline 25 Aug 2026 | 1 articles | Viewed by 2879 | Submission Open

Keywords: epilepsy; anticonvulsant; epileptic syndrome; seizure; epileptogenic; small molecule drugs

(This special issue belongs to the Section Pharmacology)

Crystal Engineering in the Pharmaceutical Sciences

edited by

Stephen Robert Byrn

submission deadline 25 Aug 2026 | 2 articles | Viewed by 2131 | Submission Open

Keywords: intermolecular interactions; cocrystals; salts; disproportionation; crystal structure prediction; space manufacturing

(This special issue belongs to the Section Medicinal Chemistry)

Drug Safety and Real-World Evidence: From Databases to Artificial Intelligence

edited by

Maria Antonietta Barbieri

submission deadline 25 Aug 2026 | 3 articles | Viewed by 2118 | Submission Open

Keywords: drug safety; real-world evidence; patient’s clinical outcomes; pharmacovigilance; pharmacoepidemiology; artificial intelligence; adverse drug reactions; inappropriate prescribing

(This special issue belongs to the Section AI in Drug Development)

Innovative Applications and Performance Optimization of Biodegradable Polymers in Drug Delivery

edited by

Nikolaos D. Bikiaris

submission deadline 25 Aug 2026 | 1 articles | Viewed by 1772 | Submission Open

Keywords: biodegradable polymers; drug delivery systems; controlled release; polymeric nanoparticles; targeted drug delivery; in vivo drug delivery; sustained release formulations

(This special issue belongs to the Section Pharmaceutical Technology)

Immunotherapy as a Promising Therapeutic Paradigm for Cancers

edited by

Gheorghița Isvoranu

and

Marioara Chiritoiu-Butnaru

submission deadline 25 Aug 2026 | 1 articles | Viewed by 874 | Submission Open

Keywords: cancer immunotherapy; cell-based therapy in cancer; immune checkpoint and co-stimulator modulators; bispecific antibodies; neoantigen-based vaccines; signal transduction inhibitors; small molecules of cancer drugs; tumor microenvironment; mechanisms of resistance

(This special issue belongs to the Section Pharmacology)

Innovative Tools for Drug Analysis and Therapeutic Drug Monitoring (TDM): 2nd Edition

edited by

Juraj Piestansky

and

Andrej Kovac

submission deadline 25 Aug 2026 | 1 articles | Viewed by 755 | Submission Open

Keywords: therapeutic drug monitoring; biologics; separation analytical methods; bioanalysis; quality control; dosage forms; green analytical chemistry; personalized medicine; clinical bioanalysis; bioanalytical methods

(This special issue belongs to the Section Pharmacology)

Network and Systems Pharmacology of Natural Products for Multi-Target Intervention in Cancer and Metabolic Disease

edited by Aleksandra Golonko

submission deadline 25 Aug 2026 | Viewed by 460 | Submission Open

Keywords: pleiotropy; multi-target; obesity; cancer; diabetes; adverse effect; metabolism; drug synthesis; drug discovery

(This special issue belongs to the Section Natural Products)

Antiparasitic Essential Oils: Mechanisms of Action, Technological Approaches, and Metabolism

edited by

Damião Pergentino de Sousa

submission deadline 25 Aug 2026 | Viewed by 379 | Submission Open

Keywords: volatile; essential oils; aromatic plants; aromas; protozoa; helminths; Trypanosoma; Leishmania

(This special issue belongs to the Section Natural Products)

Perioperative Precision in Modern Anesthesia: Efficacy and Safety of Pharmacotherapy with Risk Modulation

edited by

Michał Jan Stasiowski

submission deadline 25 Aug 2026 | Viewed by 262 | Submission Open

Keywords: perioperative precision anesthesia; anesthesia pharmacotherapy; perioperative drug management; anesthesia efficacy; anesthesia safety; risk modulation; adverse event prevention

(This special issue belongs to the Section Pharmacology)

AI-Driven Multi-Omics and Pharmacomicrobiomics: Personalizing Cardiovascular Therapeutics

edited by

Tim Dong

and Gianni Angelini

submission deadline 25 Aug 2026 | Viewed by 254 | Submission Open

Keywords: pharmacomicrobiomics; multi-omics data integration; artificial intelligence in drug discovery; atrial fibrillation & anticoagulant metabolism; interindividual variability in drug response (IVDR); gut–heart axis; precision cardiovascular medicine

(This special issue belongs to the Section AI in Drug Development)

Vitamin D and Its Derivatives in Pharmacology: Mechanisms and Therapeutic Applications

edited by

Agnieszka Sliwinska

submission deadline 27 Aug 2026 | 5 articles | Viewed by 9965 | Submission Open

Keywords: vitamin D, synthesis and metabolism; vitamin D derivatives; vitamin D deficiency related diseases; clinical trials on vitamin D and/or its derivatives

(This special issue belongs to the Section Pharmacology)

Innovative Drug Strategies in Chronic Disease Management: Addressing Non-Adherence and Improving Therapeutic Outcomes

edited by

Eduardo Gutiérrez-Abejón

and

F. Javier Alvarez

submission deadline 27 Aug 2026 | 4 articles | Viewed by 6390 | Submission Open

Keywords: adherence; persistence; chronic diseases; therapeutic strategies; individualized therapy; personalized medicine; clinical pharmacology; clinical trials; observational studies; real-world data studies

(This special issue belongs to the Section Pharmacology)

Drug Candidates for the Treatment of Oral Cancer and Oral Cancer Pain, 2nd Edition

edited by

Cara B. Gonzales

submission deadline 27 Aug 2026 | Viewed by 484 | Submission Open

Keywords: oral cancer; oral cancer pain; drug discovery; natural compounds; immunotherapy; small molecule inhibitors; biomarkers

(This special issue belongs to the Section Pharmacology)

A Commemorative Special Issue in Honor of Professor Carlos Alberto Manssour Fraga: Medicinal Chemistry’s Efforts to Discover Novel Bioactive Molecules for Complex Diseases

edited by

Luzineide Tinoco

and

Pedro De Sena Murteira Pinheiro

submission deadline 28 Aug 2026 | 7 articles | Viewed by 25069 | Submission Open

Keywords: medicinal chemistry; bioactive molecules; complex diseases; cardiovascular diseases; diabetes; cancer; neurodegenerative disorders; drug discovery; synthetic chemistry; target identification; structure–activity relationship; preclinical evaluation

(This special issue belongs to the Section Medicinal Chemistry)

Multitargeted Compounds: A Promising Approach in Medicinal Chemistry—2nd Edition

edited by

Abdallah Hamze

submission deadline 28 Aug 2026 | 1 articles | Viewed by 882 | Submission Open

Keywords: multitargeted compounds; medicinal chemistry; rational design; drug discovery; synergistic effects; emerging technologies; therapeutic applications; dual compounds

(This special issue belongs to the Section Medicinal Chemistry)

Natural Compounds and Extracts Loaded into Advanced Delivery Platforms

edited by Judyta Cielecka-Piontek,

Anna Stasiłowicz-Krzemień

and

Nunzio Denora

submission deadline 30 Aug 2026 | Viewed by 364 | Submission Open

Keywords: bioavailability enhancement; biopolymer-based carriers; controlled delivery; nanoencapsulation; nanocarriers; natural bioactive compounds; phytochemical delivery systems; plant extract formulations; sustainable delivery systems; targeted delivery

(This special issue belongs to the Section Natural Products)

Plant-Based Extracts and the Therapeutic Potential of Bioactive Compounds, 2nd Edition

edited by

Grażyna Zgórka

submission deadline 31 Aug 2026 | 9 articles | Viewed by 20086 | Submission Open

Keywords: plant extracts; herbal medicinal products; standardization; phytochemical profiling; bioactive plant compounds; therapeutic effects

(This special issue belongs to the Section Natural Products)

Bioactive Compounds from Plants and Foods: From Traditional Medicine to Modern Applications in Nutrition and Health

edited by

Sendar Nery-Flores

,

Filiberto Gutierrez-Gutierrez

, Walter Trujillo-Rangel and

Raúl Rodríguez-Herrera

submission deadline 31 Aug 2026 | 5 articles | Viewed by 7447 | Submission Open

Keywords: herbal extracts; natural compounds; nutraceuticals; bioactive compounds; in vitro and in vivo studies; biological activities; phytochemistry; natural product drug discovery; computational screening of natural products; nanomaterials for natural product extraction

(This special issue belongs to the Section Natural Products)

Metabolism, Inflammation and Neurodegeneration: Natural Compounds as Therapeutic Agents

edited by Pedro Cisternas

submission deadline 31 Aug 2026 | 3 articles | Viewed by 4346 | Submission Open

Keywords: neurodegenerative diseases; natural compounds; metabolic dysfunction; neuroinflammation; therapeutic strategies

(This special issue belongs to the Section Natural Products)

Applications of Pharmacogenomics in Precision Medicine

edited by

Kariofyllis Karamperis

, Branka Zukic and

Fernanda Rodrigues-Soares

submission deadline 31 Aug 2026 | 2 articles | Viewed by 4138 | Submission Open

Keywords: personalized medicine; pharmacogenomics; drug–gene interactions; adverse drug reactions; pharmacogenomic biomarkers; multi-omics; population pharmacogenomics; precision therapeutics

(This special issue belongs to the Section Pharmacology)

Pyrazole and Its Derivatives: Drug Design, Synthesis, and Biological Evaluation

edited by

Matteo Lusardi

and

Marco Ponassi

submission deadline 31 Aug 2026 | 3 articles | Viewed by 3344 | Submission Open

Keywords: medicinal chemistry; drug design; drug discovery; pyrazole-based compounds; innovative synthesis; structure–activity relationships; biological activities; drug-like properties

(This special issue belongs to the Section Medicinal Chemistry)

Novel Vasoactive and Anti-Inflammatory Agents: From Mechanisms to Therapeutic Applications

edited by

Thyago Moreira De Queiroz

and Alice Valença Araújo

submission deadline 31 Aug 2026 | 3 articles | Viewed by 3228 | Submission Open

Keywords: vasorelaxation; inflammation; oxidative stress; nitric oxide; natural and synthetic products; blood pressure

(This special issue belongs to the Section Pharmacology)

Research on Guanidine-Based Drugs: Synthesis, Antiparasitic, Antifungal, Antiviral, and Anticancer Activities

edited by

Eduardo René Pérez González

,

Eduardo Henrique Zampieri

, Francisco Jaime Bezerra Mendonça-Junior,

Eduardo Maffud Cilli

and

Ana Marisa Fusco Almeida

submission deadline 31 Aug 2026 | 2 articles | Viewed by 2448 | Submission Open

Keywords: guanidine derivatives; medicinal chemistry; SAR analysis; neglected diseases; antiparasitic; antifungal; antiviral; anticancer; drug development

(This special issue belongs to the Section Medicinal Chemistry)

Cancer Therapeutics: Drug Repurposing and Computational Strategies

edited by

Minh Tuan Nguyen

submission deadline 31 Aug 2026 | 3 articles | Viewed by 2260 | Submission Open

Keywords: cancer therapeutics; drug repurposing; computer-aided drug design (CADD); molecular dynamics simulation; virtual screening; targeted therapy; structure-based drug design; molecular docking; pharmacophore modeling

(This special issue belongs to the Section AI in Drug Development)

New Perspective of Antiviral Drugs

edited by

Grigoris Zoidis

submission deadline 31 Aug 2026 | 1 articles | Viewed by 2193 | Submission Open

Keywords: antiviral drugs; antiviral agents; small organic molecules; metal complexes; natural products

(This special issue belongs to the Section Medicinal Chemistry)

Current Advances, Applications and Future Development of Transition Metal Complexes, 2nd Edition

edited by

Domenico Iacopetta

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1767 | Submission Open

Keywords: transition metal complexes; synthesis; catalysis; ligands; biological activity; applications; enzyme inhibition

(This special issue belongs to the Section Medicinal Chemistry)

Application of Natural Products in Retinal Disorders Therapy

edited by

Francesca Corsi

and

Maria Claudia Gargini

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1730 | Submission Open

Keywords: natural products; retinal disorders; neuroprotection; oxidative stress; retinal inflammation; retinal neurodegeneration; nutraceuticals; in vitro and in vivo retinal models

(This special issue belongs to the Section Natural Products)

Molecular Systems for the Delivery of Drugs and Contrast Agents, 2nd Edition

edited by

Angelo Maspero

,

Luca Nardo

and

Marco Lamperti

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1724 | Submission Open

Keywords: biomarker-targeted drugs; contrast media for diagnostic imaging; drug delivery systems; photoactivated drugs and photoswitches; theranostics; liposomes; biomaterials-based drugs and drug shuttles (e.g., DNA origami); biomimetic materials; nanoparticle applications to diagnostics and therapy; in silico drug design

(This special issue belongs to the Section Medicinal Chemistry)

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