Application of Natural Products in Retinal Disorders Therapy
A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Natural Products".
Deadline for manuscript submissions: 31 August 2026 | Viewed by 907
Special Issue Editors
Interests: neurodegeneration; retinitis pigmentosa; natural products; neuroprotection; anti-oxidant and anti-inflammatory compounds; diabetic retinopathy; in vitro and in vivo retinal models
Special Issue Information
Dear Colleagues,
Retinal disorders, including age-related macular degeneration, diabetic retinopathy, glaucoma, and inherited retinal dystrophies, represent a major cause of visual impairment worldwide and are characterised by progressive structural and functional alterations of the retina, ultimately resulting in photoreceptor dysfunction and vision loss. Despite significant advances in pharmacological interventions, current therapeutic options often remain limited by incomplete efficacy, adverse effects, or high costs. In this context, natural products have emerged as a promising source of bioactive compounds with potential applications in retinal disease prevention and therapy.
This Special Issue, “Application of Natural Products in Retinal Disorders Therapy”, aims to provide a comprehensive overview of recent advances in the use of natural compounds, plant extracts, marine-derived substances, and nutraceuticals for the management of retinal pathologies. Particular attention is given to compounds exhibiting antioxidant, anti-inflammatory, anti-angiogenic, and neuroprotective properties, which are key mechanisms involved in retinal degeneration and dysfunction.
We welcome original research articles, reviews, and short communications that explore the effects of natural treatments on retinal structure and function. Particular emphasis is placed on studies investigating cellular and molecular mechanisms of action, including pathways involved in photoreceptor survival, retinal metabolism, oxidative stress, inflammation, neurodegeneration, and microvascular alterations. Contributions addressing functional outcomes, innovative delivery systems, bioavailability, and combination strategies with conventional therapies are also encouraged.
By bringing together multidisciplinary contributions from physiological, pharmacological, and molecular approaches, this Special Issue aims to stimulate scientific discussion and foster the development of novel, safe, and effective therapeutic strategies for retinal disorders. Ultimately, the collected contributions seek to foster the development of safe, effective, and mechanism-based therapeutic strategies to slow retinal degeneration and improve visual function.
Dr. Francesca Corsi
Dr. Maria Claudia Gargini
Guest Editors
Manuscript Submission Information
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Keywords
- natural products
- retinal disorders
- neuroprotection
- oxidative stress
- retinal inflammation
- retinal neurodegeneration
- nutraceuticals
- in vitro and in vivo retinal models
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