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Most Cited

  • Article
  • Open Access
114 Citations
20,954 Views
11 Pages

20 December 2022

This study sought to ascertain the prevalence of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) among a sample of 465 patients with Long COVID. The participants completed three questionnaires: (1) a new questionnaire measuring both the f...

  • Review
  • Open Access
48 Citations
5,225 Views
14 Pages

Macrophages in Recurrent Glioblastoma as a Prognostic Factor in the Synergistic System of the Tumor Microenvironment

  • Nicola Montemurro,
  • Bhavya Pahwa,
  • Anish Tayal,
  • Anushruti Shukla,
  • Manuel De Jesus Encarnacion,
  • Issael Ramirez,
  • Renat Nurmukhametov,
  • Vishal Chavda and
  • Antonella De Carlo

23 April 2023

Glioblastoma (GBM) is a common and highly malignant primary tumor of the central nervous system in adults. Ever more recent papers are focusing on understanding the role of the tumor microenvironment (TME) in affecting tumorigenesis and the subsequen...

  • Review
  • Open Access
47 Citations
12,157 Views
21 Pages

Long COVID, the Brain, Nerves, and Cognitive Function

  • Allison B. Reiss,
  • Caitriona Greene,
  • Christopher Dayaramani,
  • Steven H. Rauchman,
  • Mark M. Stecker,
  • Joshua De Leon and
  • Aaron Pinkhasov

SARS-CoV-2, a single-stranded RNA coronavirus, causes an illness known as coronavirus disease 2019 (COVID-19). Long-term complications are an increasing issue in patients who have been infected with COVID-19 and may be a result of viral-associated sy...

  • Review
  • Open Access
34 Citations
18,307 Views
21 Pages

The Management of Intracranial Aneurysms: Current Trends and Future Directions

  • Aviraj S. Deshmukh,
  • Stefano M. Priola,
  • Aris H. Katsanos,
  • Gianluca Scalia,
  • Aderaldo Costa Alves,
  • Abhilekh Srivastava and
  • Christine Hawkes

3 January 2024

Intracranial aneurysms represent a major global health burden. Rupture of an intracranial aneurysm is a catastrophic event. Without access to treatment, the fatality rate is 50% in the first 30 days. Over the last three decades, treatment approaches...

  • Review
  • Open Access
31 Citations
31,063 Views
16 Pages

Chronic Administration of Melatonin: Physiological and Clinical Considerations

  • Donald Givler,
  • Amy Givler,
  • Patrick M. Luther,
  • Danielle M. Wenger,
  • Shahab Ahmadzadeh,
  • Sahar Shekoohi,
  • Amber N. Edinoff,
  • Bradley K. Dorius,
  • Carlo Jean Baptiste and
  • Elyse M. Cornett
  • + 2 authors

15 March 2023

Background: Exogenous melatonin is commonly used to treat insomnia, other sleep problems, and numerous medical illnesses, including Alzheimer’s disease, autism spectrum disorder, and mild cognitive impairment in adults and children. There is ev...

  • Review
  • Open Access
29 Citations
9,560 Views
16 Pages

Oxidative Stress and Neurodegeneration: Insights and Therapeutic Strategies for Parkinson’s Disease

  • Erjola Bej,
  • Patrizia Cesare,
  • Anna Rita Volpe,
  • Michele d’Angelo and
  • Vanessa Castelli

29 April 2024

Parkinson’s disease (PD) is a progressive neurodegenerative condition marked by the gradual deterioration of dopaminergic neurons in the substantia nigra. Oxidative stress has been identified as a key player in the development of PD in recent s...

  • Review
  • Open Access
24 Citations
23,863 Views
54 Pages

Migraine: Advances in the Pathogenesis and Treatment

  • Horia Pleș,
  • Ioan-Alexandru Florian,
  • Teodora-Larisa Timis,
  • Razvan-Adrian Covache-Busuioc,
  • Luca-Andrei Glavan,
  • David-Ioan Dumitrascu,
  • Andrei Adrian Popa,
  • Andrei Bordeianu and
  • Alexandru Vlad Ciurea

31 August 2023

This article presents a comprehensive review on migraine, a prevalent neurological disorder characterized by chronic headaches, by focusing on their pathogenesis and treatment advances. By examining molecular markers and leveraging imaging techniques...

  • Systematic Review
  • Open Access
22 Citations
4,747 Views
17 Pages

Monocyte to HDL and Neutrophil to HDL Ratios as Potential Ischemic Stroke Prognostic Biomarkers

  • Aimilios Gkantzios,
  • Dimitrios Tsiptsios,
  • Vaia Karapepera,
  • Stella Karatzetzou,
  • Stratis Kiamelidis,
  • Pinelopi Vlotinou,
  • Erasmia Giannakou,
  • Evangeli Karampina,
  • Katerina Paschalidou and
  • Nikolaos Kourkoutsakis
  • + 3 authors

20 February 2023

Ischemic stroke (IS) exhibits significant heterogeneity in terms of etiology and pathophysiology. Several recent studies highlight the significance of inflammation in the onset and progression of IS. White blood cell subtypes, such as neutrophils and...

  • Review
  • Open Access
22 Citations
9,458 Views
19 Pages

Pain Catastrophizing: How Far Have We Come

  • Katarina Simic,
  • Boris Savic and
  • Nebojsa Nick Knezevic

26 April 2024

The perception of pain is strongly influenced by various social, emotional, and cognitive factors. A psychological variable which has consistently been shown to exert its influence on pain is a cognitive process referred to as pain catastrophizing. N...

  • Article
  • Open Access
21 Citations
4,243 Views
21 Pages

Inflammation and Treatment-Resistant Depression from Clinical to Animal Study: A Possible Link?

  • Lara F. Almutabagani,
  • Raghad A. Almanqour,
  • Jawza F. Alsabhan,
  • Abdulaziz M. Alhossan,
  • Maha A. Alamin,
  • Haya M. Alrajeh,
  • Asma S. Alonazi,
  • Ahmed M. El-Malky and
  • Nouf M. Alrasheed

16 January 2023

The aim of this study was to investigate the relationship between treatment-resistant depression (TRD) and inflammation in humans and experimental models. For the human study, a retrospective cohort study was conducted with 206 participants; half wer...

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Neurol. Int. - ISSN 2035-8377