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Most Cited

  • Review
  • Open Access
49 Citations
12,599 Views
21 Pages

Long COVID, the Brain, Nerves, and Cognitive Function

  • Allison B. Reiss,
  • Caitriona Greene,
  • Christopher Dayaramani,
  • Steven H. Rauchman,
  • Mark M. Stecker,
  • Joshua De Leon and
  • Aaron Pinkhasov

SARS-CoV-2, a single-stranded RNA coronavirus, causes an illness known as coronavirus disease 2019 (COVID-19). Long-term complications are an increasing issue in patients who have been infected with COVID-19 and may be a result of viral-associated sy...

  • Review
  • Open Access
49 Citations
5,352 Views
14 Pages

Macrophages in Recurrent Glioblastoma as a Prognostic Factor in the Synergistic System of the Tumor Microenvironment

  • Nicola Montemurro,
  • Bhavya Pahwa,
  • Anish Tayal,
  • Anushruti Shukla,
  • Manuel De Jesus Encarnacion,
  • Issael Ramirez,
  • Renat Nurmukhametov,
  • Vishal Chavda and
  • Antonella De Carlo

23 April 2023

Glioblastoma (GBM) is a common and highly malignant primary tumor of the central nervous system in adults. Ever more recent papers are focusing on understanding the role of the tumor microenvironment (TME) in affecting tumorigenesis and the subsequen...

  • Review
  • Open Access
38 Citations
19,372 Views
21 Pages

The Management of Intracranial Aneurysms: Current Trends and Future Directions

  • Aviraj S. Deshmukh,
  • Stefano M. Priola,
  • Aris H. Katsanos,
  • Gianluca Scalia,
  • Aderaldo Costa Alves,
  • Abhilekh Srivastava and
  • Christine Hawkes

3 January 2024

Intracranial aneurysms represent a major global health burden. Rupture of an intracranial aneurysm is a catastrophic event. Without access to treatment, the fatality rate is 50% in the first 30 days. Over the last three decades, treatment approaches...

  • Review
  • Open Access
35 Citations
33,381 Views
16 Pages

Chronic Administration of Melatonin: Physiological and Clinical Considerations

  • Donald Givler,
  • Amy Givler,
  • Patrick M. Luther,
  • Danielle M. Wenger,
  • Shahab Ahmadzadeh,
  • Sahar Shekoohi,
  • Amber N. Edinoff,
  • Bradley K. Dorius,
  • Carlo Jean Baptiste and
  • Alan D. Kaye
  • + 2 authors

15 March 2023

Background: Exogenous melatonin is commonly used to treat insomnia, other sleep problems, and numerous medical illnesses, including Alzheimer’s disease, autism spectrum disorder, and mild cognitive impairment in adults and children. There is ev...

  • Review
  • Open Access
32 Citations
10,077 Views
16 Pages

Oxidative Stress and Neurodegeneration: Insights and Therapeutic Strategies for Parkinson’s Disease

  • Erjola Bej,
  • Patrizia Cesare,
  • Anna Rita Volpe,
  • Michele d’Angelo and
  • Vanessa Castelli

29 April 2024

Parkinson’s disease (PD) is a progressive neurodegenerative condition marked by the gradual deterioration of dopaminergic neurons in the substantia nigra. Oxidative stress has been identified as a key player in the development of PD in recent s...

  • Review
  • Open Access
27 Citations
24,898 Views
54 Pages

Migraine: Advances in the Pathogenesis and Treatment

  • Horia Pleș,
  • Ioan-Alexandru Florian,
  • Teodora-Larisa Timis,
  • Razvan-Adrian Covache-Busuioc,
  • Luca-Andrei Glavan,
  • David-Ioan Dumitrascu,
  • Andrei Adrian Popa,
  • Andrei Bordeianu and
  • Alexandru Vlad Ciurea

31 August 2023

This article presents a comprehensive review on migraine, a prevalent neurological disorder characterized by chronic headaches, by focusing on their pathogenesis and treatment advances. By examining molecular markers and leveraging imaging techniques...

  • Review
  • Open Access
25 Citations
10,490 Views
19 Pages

Pain Catastrophizing: How Far Have We Come

  • Katarina Simic,
  • Boris Savic and
  • Nebojsa Nick Knezevic

26 April 2024

The perception of pain is strongly influenced by various social, emotional, and cognitive factors. A psychological variable which has consistently been shown to exert its influence on pain is a cognitive process referred to as pain catastrophizing. N...

  • Systematic Review
  • Open Access
23 Citations
4,926 Views
17 Pages

Monocyte to HDL and Neutrophil to HDL Ratios as Potential Ischemic Stroke Prognostic Biomarkers

  • Aimilios Gkantzios,
  • Dimitrios Tsiptsios,
  • Vaia Karapepera,
  • Stella Karatzetzou,
  • Stratis Kiamelidis,
  • Pinelopi Vlotinou,
  • Erasmia Giannakou,
  • Evangeli Karampina,
  • Katerina Paschalidou and
  • Konstantinos Vadikolias
  • + 3 authors

20 February 2023

Ischemic stroke (IS) exhibits significant heterogeneity in terms of etiology and pathophysiology. Several recent studies highlight the significance of inflammation in the onset and progression of IS. White blood cell subtypes, such as neutrophils and...

  • Review
  • Open Access
22 Citations
21,738 Views
11 Pages

The Role of Alpha-2 Agonists for Attention Deficit Hyperactivity Disorder in Children: A Review

  • Elisa E. Neuchat,
  • Brooke E. Bocklud,
  • Kali Kingsley,
  • William T. Barham,
  • Patrick M. Luther,
  • Shahab Ahmadzadeh,
  • Sahar Shekoohi,
  • Elyse M. Cornett and
  • Alan D. Kaye

Introduction: Attention Deficit Hyperactivity Disorder (ADHD) is one of the most common neurodevelopmental disorders, characterized by the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), which is marked by symptoms such...

  • Review
  • Open Access
22 Citations
8,599 Views
16 Pages

Processing Speed and Attentional Shift/Mental Flexibility in Patients with Stroke: A Comprehensive Review on the Trail Making Test in Stroke Studies

  • Anna Tsiakiri,
  • Foteini Christidi,
  • Dimitrios Tsiptsios,
  • Pinelopi Vlotinou,
  • Sofia Kitmeridou,
  • Paschalina Bebeletsi,
  • Christos Kokkotis,
  • Aspasia Serdari,
  • Konstantinos Tsamakis and
  • Konstantinos Vadikolias
  • + 1 author

23 January 2024

The Trail Making Test (TMT) is one of the most commonly administered tests in clinical and research neuropsychological settings. The two parts of the test (part A (TMT-A) and part B (TMT-B)) enable the evaluation of visuoperceptual tracking and proce...

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Neurol. Int. - ISSN 2035-8377