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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Current Trends in Materials for Beauty and Health submission deadline 20 Sep 2025 | Viewed by 923 | Submission Open
Keywords: beauty; health; biomaterials; eco-friendly; natural products; cosmetics
(This special issue belongs to the Section Materials Chemistry)
Critical Quality Attributes of Natural Products
edited by Luca Giovanni Regazzoni
submission deadline 28 Sep 2025 | 1 articles | Viewed by 1285 | Submission Open
Keywords: critical quality attributes; natural product characterization; bioactive natural compounds; human health
(This special issue belongs to the Section Analytical Chemistry)
Bioactive and Nutritional Molecules: From Natural Sources to Therapeutic and Health Applications
edited by
submission deadline 30 Sep 2025 | 7 articles | Viewed by 38695 | Submission Open
Keywords: bioactive and nutritional molecules; natural therapeutic agents; bioactive compounds
(This special issue belongs to the Section Cross-Field Chemistry)
Bioactive Molecules Targeting Inflammation Processes in Related Diseases—2nd Edition
edited by
submission deadline 30 Sep 2025 | 5 articles | Viewed by 24748 | Submission Open
Keywords: plant bioactive compounds; inflammation; chronic diseases; in vivo; in vitro
(This special issue belongs to the Section Natural Products Chemistry)
Advances in Targeted Delivery of Nanomedicines submission deadline 30 Sep 2025 | 6 articles | Viewed by 24584 | Submission Open
Keywords: nanomedicines; drug delivery; target delivery; nanoscience; cancer signalling
(This special issue belongs to the Section Medicinal Chemistry)
Phytochemistry, Human Health and Molecular Mechanisms submission deadline 30 Sep 2025 | 12 articles | Viewed by 21882 | Submission Open
Keywords: bioactive compounds; bioavailability; extraction methods; biological activities; functional applications; nutraceuticals; human metabolism; toxicity; bioactive-gut microbiota relationships
(This special issue belongs to the Section Natural Products Chemistry)
Chromatographic Methods for Monitoring Food Safety and Quality submission deadline 30 Sep 2025 | 7 articles | Viewed by 17986 | Submission Open
Keywords: antibiotics; bioactive compounds; chromatography; contaminants; food chemistry; food authentication; food safety; food quality; food safety; method validation; microplastics; pesticides; veterinary drugs
(This special issue belongs to the Section Analytical Chemistry)
Metal-Catalyzed Organic Transformations: Expanding Horizons in Synthetic Methodology
edited by Chen Chen
submission deadline 30 Sep 2025 | 9 articles | Viewed by 17981 | Submission Open
Keywords: multicomponent reactions; transition metal catalysis; organometallic chemistry; electrosynthesis; photocatalysis; green organic synthesis; bioactive molecules
(This special issue belongs to the Section Organic Chemistry)
Metal Complexes for Optical and Electronics Applications submission deadline 30 Sep 2025 | 8 articles | Viewed by 16763 | Submission Open
Keywords: coordination chemistry; metal complexes; transition metals; lanthanides; luminescence; nonlinear optics; photo-switching; conductivity
(This special issue belongs to the Section Applied Chemistry)
Natural Products and Microbiology in Human Health
edited by
submission deadline 30 Sep 2025 | 8 articles | Viewed by 15173 | Submission Open
Keywords: traditional medicine; antibiotics; antibiotic natural products; probiotics; novel antimicrobial therapies; microbial toxins; phytochemicals; antibiotic-resistant bacteria; drug potentiation
(This special issue belongs to the Section Medicinal Chemistry)
Application of Computational Studies for Elucidation of Protein Structure and Function
edited by
submission deadline 30 Sep 2025 | 12 articles | Viewed by 13722 | Submission Open
Keywords: simulation; artificial intelligence; bioinformatics; sequence analysis; protein assembly; drug discovery; theory
(This special issue belongs to the Section Chemical Biology)
Recent Research Progress of Novel Ion Adsorbents submission deadline 30 Sep 2025 | 8 articles | Viewed by 12715 | Submission Open
Keywords: synthesis of adsorbents; adsorbents regeneration; ionic adsorbates; purification of water; removal of impurities; adsorption mechanisms; desorption; equilibrium data; adsorption isotherms; kinetic models
(This special issue belongs to the Section Physical Chemistry)
Heterocyclic Compounds: Synthesis, Application and Theoretical Study
edited by
submission deadline 30 Sep 2025 | 5 articles | Viewed by 9956 | Submission Open
Keywords: synthesis and transformation of heterocycles; structural chemistry; reaction mechanisms; stereochemistry; regiochemistry; quantum chemical computations; biological activity of heterocyclic compounds; green chemistry
(This special issue belongs to the Section Organic Chemistry)
Natural Compounds in Modern Therapies, 2nd Edition submission deadline 30 Sep 2025 | 5 articles | Viewed by 9648 | Submission Open
Keywords: natural compounds; plant extract; nutraceuticals; anticancer activity; antimicrobial activity; anti-inflammatory activity; synergistic effect
(This special issue belongs to the Section Natural Products Chemistry)
Extraction and Analysis of New Bioactive Compounds Derived from Natural Products, 2nd Edition submission deadline 30 Sep 2025 | 10 articles | Viewed by 9191 | Submission Open
Keywords: phytochemicals; natural products; traditional medicine; liquid– liquid extraction; hydro distillation and steam distillation; solid-phase extraction; Soxhlet extraction; pressurized liquid extraction; supercritical fluid extraction; ultrasound-assisted extraction; microwave-assisted extraction; enzyme-assisted extraction; pulsed electric field extraction; HPLC; HPLC-MS; GC-MS; NMR; IR; in vitro assay; in vivo assay; antioxidant; anti-inflammatory; antimicrobial; antitumoral activity
(This special issue belongs to the Section Natural Products Chemistry)
Anti-inflammatory Activities of Natural Products—Third Edition submission deadline 30 Sep 2025 | 5 articles | Viewed by 8581 | Submission Open
Keywords: inflammation; anti-inflammatory; natural products; pharmacology; plant; marine
(This special issue belongs to the Section Natural Products Chemistry)
Exclusive Feature Papers in Physical Chemistry, 3rd Edition
edited by
submission deadline 30 Sep 2025 | 13 articles | Viewed by 8269 | Submission Open
Keywords: catalysis; energy electrochemistry; kinetic; interface chemistry; biophysical chemistry
(This special issue belongs to the Section Physical Chemistry)
Organic and Inorganic Luminescent Materials, 2nd Edition
edited by
submission deadline 30 Sep 2025 | 7 articles | Viewed by 7675 | Submission Open
Keywords: luminescent materials; molecular design; luminescent mechanisms and processes; luminescent devices; display; lighting; detection
(This special issue belongs to the Section Photochemistry)
Novel Inhibitors: Design, Synthesis, Biological Activities and Modelling Studies submission deadline 30 Sep 2025 | 4 articles | Viewed by 7210 | Submission Open
Keywords: drug design; medicinal chemistry; organic synthesis; total synthesis; multi-drug resistance; biological activity; anticancer; heterocyclic compounds; cytotoxicity; structure– activity relationship; molecular modeling
(This special issue belongs to the Section Medicinal Chemistry)
Natural Products in Anticancer Activity: 2nd Edition submission deadline 30 Sep 2025 | 5 articles | Viewed by 7171 | Submission Open
Keywords: natural products; anticancer; drug; nature; molecule
(This special issue belongs to the Section Natural Products Chemistry)
Energy Storage Materials: Synthesis and Application
edited by Yuanyuan Ma
submission deadline 30 Sep 2025 | 5 articles | Viewed by 6996 | Submission Open
Keywords: energy storage; inorganic material; organic material; sol– gel method; hydrothermal; coprecipitation method; lithium-ion battery; lithium– sulfur battery; air battery; supercapacitor; aqueous battery
(This special issue belongs to the Section Applied Chemistry)
Green Chemistry Approaches to Analysis and Environmental Remediation
edited by
submission deadline 30 Sep 2025 | 8 articles | Viewed by 6923 | Submission Open
Keywords: chromatography; mass spectrometry; extraction; green analytical chemistry; emerging contaminants
(This special issue belongs to the Section Analytical Chemistry)
Photocatalytic Materials and Photocatalytic Reactions, 2nd Edition
edited by and
submission deadline 30 Sep 2025 | 7 articles | Viewed by 6362 | Submission Open
Keywords: photocatalysts; carbon neutral; charge carrier separation; photocatalytic mechanism; photoredox reaction; nanocomposites
(This special issue belongs to the Section Photochemistry)
Natural Products: Extraction, Analysis and Biological Activities
edited by and Łukasz Paprotny
submission deadline 30 Sep 2025 | 5 articles | Viewed by 5917 | Submission Open
Keywords: plant products; secondary metabolites; extraction; analysis; quality of natural products; biological activity; health-promoting properties; agricultural waste
(This special issue belongs to the Section Natural Products Chemistry)
Discovery of Antibacterial Drugs
edited by
submission deadline 30 Sep 2025 | 3 articles | Viewed by 5844 | Submission Open
Keywords: antibacterial effect; antibiotics; drug discovery; natural compounds; pharmacodynamic and pharmacokinetic characteristics
(This special issue belongs to the Section Medicinal Chemistry)
Innovative Analytical Techniques in Food Chemistry
edited by , and Ying Gu
submission deadline 30 Sep 2025 | 5 articles | Viewed by 5793 | Submission Open
Keywords: sensor; biosensor; food safety; advanced functional material; dual-mode; visualization; array sensor; paper-based sensor
(This special issue belongs to the Section Food Chemistry)
New Insight in Catalysis and Electrocatalysis for CO2 Conversion submission deadline 30 Sep 2025 | 2 articles | Viewed by 5456 | Submission Open
Keywords: CO2; fine chemicals; bulk chemicals; catalysis; electrocatalysis; surfaces
(This special issue belongs to the Section Green Chemistry)
Exploring Analytical Techniques in Pharmaceutical and Biomedical Analysis
edited by and
submission deadline 30 Sep 2025 | 5 articles | Viewed by 5368 | Submission Open
Keywords: pharmaceutical analysis; biomedical analysis; chromatographic analysis; spectroscopic analysis; mass spectrometry analysis; capillary electrophoresis; electrochemical analysis
(This special issue belongs to the Section Medicinal Chemistry)
Natural Products for the Treatment of Diabetes and Obesity II
edited by
submission deadline 30 Sep 2025 | 2 articles | Viewed by 5136 | Submission Open
Keywords: natural products; bioactive compounds; obesity; diabetes; metabolic syndrome; human health; molecular mechanism; nutrients
(This special issue belongs to the Section Natural Products Chemistry)
Materials for Emerging Electrochemical Devices—2nd Edition submission deadline 30 Sep 2025 | 4 articles | Viewed by 5106 | Submission Open
Keywords: solid-state devices; batteries; electrochromic devices; smart windows; electrochemical devices
(This special issue belongs to the Section Materials Chemistry)
Anticancer Natural Products
edited by Zongtao Tom Lin
submission deadline 30 Sep 2025 | 3 articles | Viewed by 5078 | Submission Open
Keywords: anticancer; drug discovery; chemical biology; natural products; analytical methods; bioactive compounds; cancer therapy
(This special issue belongs to the Section Natural Products Chemistry)
Novel Metabolism-Related Biomarkers in Cancer submission deadline 30 Sep 2025 | 3 articles | Viewed by 4746 | Submission Open
Keywords: cancer biomarkers; personalized medicine; metabolism; glucose; amino acid; glutamine; lipid; iron
(This special issue belongs to the Section Bioorganic Chemistry)
Therapeutic Agents for Neurodegenerative Disorders—2nd Edition
edited by
submission deadline 30 Sep 2025 | 4 articles | Viewed by 4672 | Submission Open
Keywords: beta amyloid; tau; alpha-synuclein; huntingtin; autophagy; neuromodulators; neurotrophins; natural compounds; neuroinflammation; vascular dysfunction; neuronal death; drug development; therapeutic biomarkers; blood– brain barrier; small-molecule therapeutics; theranostics
(This special issue belongs to the Section Medicinal Chemistry)
Novel Functional Nanomaterials: Synthesis, Characterization and Applications
edited by Haoyan Cheng and
submission deadline 30 Sep 2025 | 4 articles | Viewed by 4311 | Submission Open
Keywords: nanomaterials; biomedicine; synthesis; characterization; applications; fabrication; optical properties; electrical properties; magnetic properties; mechanical properties; nanoscience; nanotechnology
(This special issue belongs to the Section Materials Chemistry)
Advances in the Recycling of Industrial Waste: Critical Minerals in the Clean Energy Transition
edited by María Isabel Martín Hernández and
submission deadline 30 Sep 2025 | 3 articles | Viewed by 4124 | Submission Open
Keywords: waste material recycling; metal removal; metal recovery; critical metal separation; hydrometallurgical processes; pyrometallurgical process; urban mining
(This special issue belongs to the Section Green Chemistry)
Synthesis, Characterization, and Biological Evaluation of Alkaloids
edited by Yucheng Zhao
submission deadline 30 Sep 2025 | 3 articles | Viewed by 3984 | Submission Open
Keywords: biological evaluation; alkaloids; biosynthesis; synthetic biology; catalytic mechanism; biosynthesis enzymes
(This special issue belongs to the Section Natural Products Chemistry)
Chemical Composition and Bioactivities of Essential Oils, 3rd Edition submission deadline 30 Sep 2025 | 4 articles | Viewed by 3855 | Submission Open
Keywords: bioactive natural compounds; essential oils; chemical characterization; the essential oil mechanism of action; biological activities in vitro and in vivo; antitumor; antimicrobials; antioxidant; EO delivery strategies
(This special issue belongs to the Section Natural Products Chemistry)
Advanced Materials for Environmental Remediation: Design and Applications
edited by Meijuan Chen and Yuru Wang
submission deadline 30 Sep 2025 | 2 articles | Viewed by 3800 | Submission Open
Keywords: advanced materials; environmental remediation; nanomaterials; biomaterials; porous materials; composites; water purification; air purification; soil remediation
(This special issue belongs to the Section Materials Chemistry)
Enhanced Bioapplications of Biomolecules Mediated by Nanomaterials
edited by and Donghong Yu
submission deadline 30 Sep 2025 | 2 articles | Viewed by 3678 | Submission Open
Keywords: nanofunctional materials; biomolecular recognition; molecular probes; biosensors; micro/nano chips; organic optoelectronic materials; bioenergy materials
(This special issue belongs to the Section Medicinal Chemistry)
Chemistry of Nucleic Acids: From Structure to Biological Interactions
edited by and Federica D'Aria
submission deadline 30 Sep 2025 | 3 articles | Viewed by 3614 | Submission Open
Keywords: nucleic acid structures and function; modified nucleic acids; nucleic acid-targeting ligands; physicochemical studies of nucleic acids; thermodynamics and kinetics of nucleic acid structures; structure– function relationship of nucleic acids; nucleic acid– protein interactions; aptamers
(This special issue belongs to the Section Chemical Biology)
Polymeric Liquid Crystals and Applications, 2nd Edition submission deadline 30 Sep 2025 | 3 articles | Viewed by 3570 | Submission Open
Keywords: phases; structures and ordering; self-assembly; colloids; instabilities; pattern formation and chaos; fibers; biological and bio-inspired liquid crystals; polymer-liquid crystal blends; conductive liquid crystals; switchable polymers; nanostructured systems; supramolecules; polymers; elastomers and gels; photosensitive liquid crystals; confined liquid crystals; molecular design; synthesis and new materials; sensors; actuators; O-LED and polymer LCD devices; conducting polymer liquid crystals; biopolymer liquid crystals; drug delivery; mathematical modelling; novel applications of liquid crystalline systems
(This special issue belongs to the Section Applied Chemistry)
Advancements in Analytical Chemistry for the Analysis and Detection of Food and Environment
edited by
submission deadline 30 Sep 2025 | 2 articles | Viewed by 3348 | Submission Open
Keywords: analytical chemistry; food analysis; environmental analysis; innovative qualitative/quantitative detection techniques; trace analysis; food quality/safety; environmental protection/management
(This special issue belongs to the Section Analytical Chemistry)
Between Solid-State NMR and Nanoscience—a Long Journey with Great Perspectives: A Themed Issue in Honor of Professor Jacek Klinowski
edited by Leszek Stobinski and
submission deadline 30 Sep 2025 | 3 articles | Viewed by 3344 | Submission Open
Keywords: solid-state NMR; NMR; zeolites; ordered carbon nanostructures; MOFs; mathematics in crystallography
(This special issue belongs to the Section Physical Chemistry)
Catalytic Approaches in Flow Chemistry submission deadline 30 Sep 2025 | 2 articles | Viewed by 3269 | Submission Open
Keywords: organocatalysis in continuous flow; flow chemistry for the preparation of APIs; green technologies in organic synthesis; green chemistry; organic synthesis; heterogeneous catalysis; scale-up
(This special issue belongs to the Section Organic Chemistry)
The Design, Synthesis, and Biological Activity of New Drug Candidates, 2nd Edition
edited by Carolina S. Marques, and
submission deadline 30 Sep 2025 | 3 articles | Viewed by 3108 | Submission Open
Keywords: bioactive; in silico; in vitro; in vivo; ADMET; synthesis; privilege scaffold; active pharmaceutical ingredients
(This special issue belongs to the Section Medicinal Chemistry)
Fundamental Concepts and Recent Developments in Chemical Bonding
edited by Hajime Hirao
submission deadline 30 Sep 2025 | 2 articles | Viewed by 3095 | Submission Open
Keywords: conventional bonding; unconventional bonding; valence bond theory; molecular orbital theory; energy decomposition analysis; spin; aromaticity; nonbonded interactions
(This special issue belongs to the Section Cross-Field Chemistry)
New Insights into Bioactive Compounds from Natural Sources—Second Edition
edited by and
submission deadline 30 Sep 2025 | 2 articles | Viewed by 3046 | Submission Open
Keywords: bioactive plant-specialized metabolites; isolation and identification; bioactive compounds; qualitative and quantitative profiling; biotechnological strategies; biological activity; structure and bioactivity
(This special issue belongs to the Section Medicinal Chemistry)
Metabolites from Algae: Discovery, Identification and Multifaceted Applications submission deadline 30 Sep 2025 | 1 articles | Viewed by 2957 | Submission Open
Keywords: marine algae-derived metabolites; marine photosynthetic organisms as a source of drugs; nutraceuticals; cosmeceuticals; biotechnological applications of macro- and microalgae; novel strategies for industrial production of marine-derived compounds
(This special issue belongs to the Section Natural Products Chemistry)
Advances in Computational Spectroscopy, 2nd Edition
edited by and Małgorzata Biczysko
submission deadline 30 Sep 2025 | 4 articles | Viewed by 2781 | Submission Open
Keywords: spectroscopy; computational spectroscopy in inorganic chemistry; computational spectroscopy in bioinorganic chemistry; computational spectroscopy in biological systems; molecular and supramolecular structure; crystal structure; molecular modelling; time-independent and time-dependent approaches; molecular dynamics; density functional theory (DFT); time-dependent DFT (TD-DFT); coupled cluster (CC) approaches and composite schemes; bottom-up and top-down semi-experimental approaches
(This special issue belongs to the Section Computational and Theoretical Chemistry)
The Impact of Metal Complexes with Active Small Molecules in Biological Systems submission deadline 30 Sep 2025 | 2 articles | Viewed by 2733 | Submission Open
Keywords: metal complexes; active small molecules; biological systems; signaling and regulatory functions; DNA-targeted therapy; new drugs and therapies; cellular therapeutics
(This special issue belongs to the Section Inorganic Chemistry)
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