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Plant Volatile Organic Compounds: Extraction, Characterization and Biological Activities

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 1

Special Issue Editors

Institute of Agricultural and Environmental Research and Technology (IITAA), University of the Azores, 9700-042 Angra do Heroísmo, Terceira, Azores, Portugal
Interests: essential oils; plant secondary metabolites; chromatographic techniques; biological activities
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Guest Editor
Department of Physics, Chemistry and Engineering (DPCE) and Institute of Agricultural and Environmental Research and Technology (IITAA), University of Azores, 9500-321 Ponta Delgada, São Miguel, Azores, Portugal
Interests: organic chemistry; natural products; phytochemistry; essential oils; biological activities
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Volatile organic compounds (VOCs) are among the most well-known plant specialized metabolites gaining increasing attention due to their ecological functions, chemical diversity, and wide-ranging biological properties. These molecules play key roles in plant defence, communication, and adaptation, and they also hold tremendous potential for applications across the pharmaceutical, agrochemical, food, and cosmetic industries.

This Special Issue aims to gather high-quality original research and review articles that explore the extraction methods, chemical profiling, and functional properties of VOCs from a wide variety of plant species. Emphasis will be placed on sustainable and innovative extraction technologies, including green and circular approaches that valorise agricultural and forestry residues as raw materials.

We encourage submissions that address topics including, but not limited to, the following:

  • Innovative and sustainable extraction techniques (e.g., hydrodistillation, microwave-assisted extraction, supercritical fluid extraction).
  • Chemical characterization of plant VOCs using GC-MS, GC×GC, enantioselective analysis, and related methods.
  • Biological activities of plant VOCs, such as
    • Antioxidant;
    • Anti-inflammatory;
    • Antimicrobial (bacterial, fungal, viral);
    • Insecticidal and pesticidal;
    • Neuroprotective and psychopharmacological effects.
  • Structure–activity relationships (SARs),
  • Valorisation of by-products and waste biomass from agro-industrial and forestry processes
  • Ecological functions and interactions of plant VOCs
  • Formulation and delivery systems for plant VOC-based products.
This Special Issue seeks to promote the development of nature-based solutions through the integration of phytochemistry, pharmacology, biotechnology, and sustainable industrial practices.

Dr. Ana Lima
Prof. Dr. Elisabete Maria de Castro Lima
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • plant volatile organic compounds
  • biosynthesis and emission
  • essential oils
  • biological activities
  • green extraction
  • omics technologies
  • circular bioeconomy

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Published Papers

This special issue is now open for submission.
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