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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Environmental Remediation and Wind–Sand Stabilization Materials
edited by
submission deadline 30 Jun 2026 | 2 articles | Viewed by 1381 | Submission Open
Keywords: soil remediation and improvement; water purification; windbreak and sand fixation; air purification materials; natural eco-materials
(This special issue belongs to the Section Applied Chemistry)
Advances in Amylases, 2nd Edition
edited by
submission deadline 30 Jun 2026 | 1 articles | Viewed by 1329 | Submission Open
Keywords: enzyme; alpha-amylase enzyme; starch and glycogen; gut microbiome oriented study
(This special issue belongs to the Section Bioorganic Chemistry)
Nanomaterial-Based Sensors for Food Safety Analysis
edited by and
submission deadline 30 Jun 2026 | 1 articles | Viewed by 1312 | Submission Open
Keywords: nanomaterial-based sensors; electrochemical/optical sensors; pathogen/toxin/pesticide/heavy metal ion detection; point-of-care testing; on-site; all-in-one; sensitivity enhancement
(This special issue belongs to the Section Nanochemistry)
Synthesis and Characterization of Hybrid Biomaterials for Life Sciences submission deadline 30 Jun 2026 | 2 articles | Viewed by 1301 | Submission Open
Keywords: hybrid material; biomaterials; drug release; antimicrobial test; chemical characterization; natural polymers; bioactivity assessment; bioactivity
(This special issue belongs to the Section Materials Chemistry)
Natural Products and Microbiology in Human Health, 2nd Edition
edited by
submission deadline 30 Jun 2026 | 3 articles | Viewed by 1242 | Submission Open
Keywords: traditional medicine; antibiotics; antibiotic natural products; probiotics; novel antimicrobial therapies; microbial toxins; phytochemicals; antibiotic-resistant bacteria; drug potentiation
(This special issue belongs to the Section Natural Products Chemistry)
Advances in Porphyrinoid-Based Functional Materials submission deadline 30 Jun 2026 | 1 articles | Viewed by 1233 | Submission Open
Keywords: porphyrinoids; synthetic approaches; functional materials; medicine; environment; energy; sensing; catalysis
(This special issue belongs to the Section Organic Chemistry)
Recent Advances on Biomass Conversion and CO2 Valorization: Steeping Towards a Circular Economy, 2nd Edition
edited by and Eva Castillejos-Lopéz
submission deadline 30 Jun 2026 | 1 articles | Viewed by 1230 | Submission Open
Keywords: CO2 valorization; biomass conversion; catalysis
(This special issue belongs to the Section Green Chemistry)
Hybrid and Hierarchical Zeolite-Based Platforms for Sustainable Remediation and Resource Recovery
edited by and
submission deadline 30 Jun 2026 | 1 articles | Viewed by 1207 | Submission Open
Keywords: hybrid and hierarchical zeolite-based materials; environmental remediation technologies; PFAS and emerging persistent pollutants; water; air; and soil treatment; functional porous platforms; natural; synthetic; composite; and nano-zeolites; structure– contaminant interaction mechanisms; circular economy and sustainable applications
(This special issue belongs to the Section Materials Chemistry)
Unlocking the Potential of Agro-Forestry Residues: Biomolecules for Diverse Applications and Multifunctional Uses submission deadline 30 Jun 2026 | 1 articles | Viewed by 1170 | Submission Open
Keywords: waste management; recycling; lignin; tannins; cellulose; additives; eco-friendly materials; nanotechnology; sustainability; circular economy
(This special issue belongs to the Section Green Chemistry)
Boron-Containing Compounds: Chemistry, Biological Functions, and Emerging Biomedical Applications
edited by
submission deadline 30 Jun 2026 | 1 articles | Viewed by 1152 | Submission Open
Keywords: boron-containing compounds; organoboron chemistry; boron– carbohydrate complexes; boronated lipids; BNCT; boron essentiality; microbiota-accessible boron; boron-based therapeutics; boron prebiotic chemistry; molecular nutrition; membrane biology; carboranes
Design of Chemically Recyclable Polymers in Sustainable Chemistry: A Minimalist Perspective
edited by Francesco Stellacci, Youwei Ma and Ping Yu
submission deadline 30 Jun 2026 | 1 articles | Viewed by 1147 | Submission Open
Keywords: chemically recyclable polymers; sustainable polymers; biomass-based polymers; dynamic (covalent) bonds; minimalist sustainable design
(This special issue belongs to the Section Green Chemistry)
Fluorescent Molecular Tools for Neuroscience Research
edited by Sheng Xie
submission deadline 30 Jun 2026 | 1 articles | Viewed by 1113 | Submission Open
Keywords: histochemical method; fluorescent probes; brain-wide 3D imaging; neuropathology; immunofluorescence labeling; transgenic labeling; small-fluorophore labeling; metallophilic labeling; virus-based labeling
(This special issue belongs to the Section Cross-Field Chemistry)
New Achievements and Challenges in Food Chemistry, 2nd Edition
edited by and Qiuming Chen
submission deadline 30 Jun 2026 | 1 articles | Viewed by 1081 | Submission Open
Keywords: food processing innovations; alternative proteins; bioactive compounds; food safety; food storage; flavor chemistry; food enzyme design; AI-assisted technologies; novel analytical methods
(This special issue belongs to the Section Food Chemistry)
Biobased Chemicals: Environmentally Friendly Solutions for Sustainable Development, 3rd Edition
edited by
submission deadline 30 Jun 2026 | 1 articles | Viewed by 1073 | Submission Open
Keywords: bioproducts; biochar; hydrochar; by-products; biofuels; biomass; hydrothermal carbonization; torrefaction
Innovative Analytical Approaches for the Isolation and Characterization of Drugs, Metabolites and Natural Bioactive Compounds submission deadline 30 Jun 2026 | 1 articles | Viewed by 1053 | Submission Open
Keywords: analytical chemistry; chromatography; extraction; green chemistry; bioactive compounds; drugs; metabolites
(This special issue belongs to the Section Analytical Chemistry)
Drug Resistance and Antimicrobial Activities of Natural Products submission deadline 30 Jun 2026 | 1 articles | Viewed by 1017 | Submission Open
Keywords: natural products; antimicrobial resistance; antibiofilm activity; synergy; drug discovery
(This special issue belongs to the Section Natural Products Chemistry)
Extraction and Analysis of New Bioactive Compounds Derived from Natural Products, 3rd Edition submission deadline 30 Jun 2026 | 1 articles | Viewed by 995 | Submission Open
Keywords: phytochemicals; natural products; traditional medicine; liquid– liquid extraction; hydro distillation and steam distillation; solid-phase extraction; Soxhlet extraction; pressurized liquid extraction; supercritical fluid extraction; ultrasound-assisted extraction; microwave-assisted extraction; enzyme-assisted extraction; pulsed electric field extraction; HPLC; HPLC-MS; GC-MS; NMR; IR; in vitro assay; in vivo assay; antioxidant; anti-inflammatory; antimicrobial; antitumoral activity
(This special issue belongs to the Section Natural Products Chemistry)
Computational Design of Nanomaterials for Environmental and Biomedical Applications submission deadline 30 Jun 2026 | Viewed by 951 | Submission Open
Keywords: computational nanomaterials design; molecular modeling and simulation; machine learning in materials science; environmental remediation nanomaterials; nanomedicine and drug delivery; biocompatibility and safety assessment; quantum chemistry and multiscale modeling; sustainable nanotechnology
(This special issue belongs to the Section Computational and Theoretical Chemistry)
Insight into Organic Semiconductor Materials
edited by Runfeng Chen and Chao Zheng
submission deadline 30 Jun 2026 | 1 articles | Viewed by 917 | Submission Open
Keywords: organic semiconductors; organic photonics; inorganic/organic hybrid materials; excitons; electroluminescence; photovoltaics; vacuum/solution process; energy transfer
(This special issue belongs to the Section Materials Chemistry)
Ionic Liquids and Deep Eutectic Solvents: From Synthesis to Emerging Applications
edited by Marina Cvjetko Bubalo and
submission deadline 30 Jun 2026 | 1 articles | Viewed by 905 | Submission Open
Keywords: microwave-assisted organic synthesis; biotransformation; green chemistry; ionic liquids; antioxidant activity; phenolic compounds; reactor design; cytotoxicity; environmental engineering; green technology
(This special issue belongs to the Section Green Chemistry)
Chemical Composition, Antiradical Potential and Sensory Qualities of Lesser-Known Fruits submission deadline 30 Jun 2026 | 1 articles | Viewed by 879 | Submission Open
Keywords: chemical composition; lesser-known fruits; antiradical potential; sensory and instrumental analysis; health-promoting activity
(This special issue belongs to the Section Food Chemistry)
Supramolecular Catalytic Systems Build on Macrocycle-Base Host-Guest Interactions
edited by
submission deadline 30 Jun 2026 | 1 articles | Viewed by 870 | Submission Open
Keywords: supramolecular catalysis; host– guest systems; macrocycles; noncovalent interactions; microenvironments; activity; stimuli-responsiveness; enantioselectivity/selectivity; transition state stabilization; product inhibition; tandem catalysis
(This special issue belongs to the Section Organic Chemistry)
Circular Economy: Agri-Food Byproducts as Source of Bioactive Compounds, 2nd Edition submission deadline 30 Jun 2026 | 1 articles | Viewed by 868 | Submission Open
Keywords: agri-food byproducts; plant extracts; food extracts; essential oils; bioactive compounds; nutraceuticals; micromorphology; phytochemistry; health effects; eco-sustainability
(This special issue belongs to the Section Green Chemistry)
Design, Synthesis, and Photochemical Studies of Functional Dyes
edited by Liang Han
submission deadline 30 Jun 2026 | 1 articles | Viewed by 868 | Submission Open
Keywords: synthesis of functional dyes; photochemistry of dyes; organic dyes; functional organic dyes; photo-inducing materials; organic photoelectric materials
(This special issue belongs to the Section Photochemistry)
Deep Eutectic Solvents: Properties, Applications and Perspectives submission deadline 30 Jun 2026 | 1 articles | Viewed by 844 | Submission Open
Keywords: green chemistry; deep eutectic systems; physico-chemical properties; thermodynamic modelling; application development; extraction; biocatalysis; CO2 capture; electrochemistry
(This special issue belongs to the Section Green Chemistry)
Chemical Transformations and Analysis in Food: Nutrition, Flavor Compounds, and Microbiological Research submission deadline 30 Jun 2026 | 1 articles | Viewed by 842 | Submission Open
Keywords: flavor compounds; fermented food; flavor formation; flavor compound production/synthesis
(This special issue belongs to the Section Food Chemistry)
Synthesis and Characterization of Heterocycles with Potential Applications submission deadline 30 Jun 2026 | 1 articles | Viewed by 794 | Submission Open
Keywords: heterocycles; synthesis; design; characterization; green methods; applications
(This special issue belongs to the Section Organic Chemistry)
Computational Drug Design
edited by Hajime Hirao
submission deadline 30 Jun 2026 | 1 articles | Viewed by 775 | Submission Open
Keywords: AI-based drug design; molecular docking; molecular dynamics simulations; QM/MM calculations; pharmacophore modeling; cheminformatics; ADMET prediction
(This special issue belongs to the Section Medicinal Chemistry)
Topological Polymers for Advanced Materials
edited by , and Jiatao Yan
submission deadline 30 Jun 2026 | 1 articles | Viewed by 775 | Submission Open
Keywords: dendritic macromolecules; molecular brushes; polymer brushes; comb-like polymers; star polymers; graft polymers; polyrotaxanes; 2D polymers
(This special issue belongs to the Section Materials Chemistry)
Bioactive Secondary Metabolites in Natural Products submission deadline 30 Jun 2026 | 1 articles | Viewed by 765 | Submission Open
Keywords: bioactive metabolites from mushrooms; medicinal plant metabolites; pro-health secondary metabolites from natural products; antiaging natural sources metabolites; natural dietary supplements
(This special issue belongs to the Section Natural Products Chemistry)
Advances in the Chemical Analysis of Prehistoric Materials
edited by
submission deadline 30 Jun 2026 | 1 articles | Viewed by 757 | Submission Open
Keywords: archaeological tools (resins; adhesives); chromatography (gas chromatography); infrared spectroscopy; nuclear magnetic resonance (NMR); archaeobotany; archaeology; terpenoids; sesquiterpenes; volatile organic compounds (VOCs)
(This special issue belongs to the Section Analytical Chemistry)
Bioactive Natural Product Compounds in Cancer Prevention and Therapy submission deadline 30 Jun 2026 | 1 articles | Viewed by 733 | Submission Open
Keywords: natural product; cytotoxic; bioactivity mechanism; cancer; drug discovery; drug delivery; chemoprevention
(This special issue belongs to the Section Natural Products Chemistry)
Progress in Green Analytical Methods for the Detection of Trace Substances in Complex Matrices submission deadline 30 Jun 2026 | 2 articles | Viewed by 732 | Submission Open
Keywords: green analytical chemistry; greenness evaluation metrics; integrated analytical platforms; miniaturized sample preparation; green materials for sample pre-treatment; on-line and in-line sampling; automatization
(This special issue belongs to the Section Analytical Chemistry)
Carbohydrate-Based Drug Delivery Systems: Chemistry, Design, and Therapeutic Potential
edited by , and Paraskevi Papakyriakopoulou
submission deadline 30 Jun 2026 | 1 articles | Viewed by 645 | Submission Open
Keywords: carbohydrate-based drug delivery systems; polysaccharides; cyclodextrins; drug loading and release; routes of administration; in vitro– in vivo evaluation; PK/PD studies
(This special issue belongs to the Section Macromolecular Chemistry)
Nanocarriers for Diagnostics, Imaging and Drug Delivery
edited by Jie Pan and Yonghui Liu
submission deadline 30 Jun 2026 | 1 articles | Viewed by 606 | Submission Open
Keywords: nanocarriers; diagnostics; imaging; drug delivery; targeted therapy
(This special issue belongs to the Section Nanochemistry)
Ligands: Design, Syntheses, and Applications in Organometallic Catalysis
edited by
submission deadline 30 Jun 2026 | 1 articles | Viewed by 593 | Submission Open
Keywords: ligand design; organometallic catalysis; green & sustainable chemistry; industrial catalysis; synthesis & applications
(This special issue belongs to the Section Organometallic Chemistry)
Advances in Solid-State Culture for Obtaining Bioactive Molecules submission deadline 30 Jun 2026 | Viewed by 492 | Submission Open
Keywords: solid-state culture; bioactive molecules; bioactive compounds characterization; biomanufacturing process design; bioprocess optimization
Plant-Based Bioactives and Sustainable Sources: Unlocking the Potential of Underutilized Resources submission deadline 30 Jun 2026 | Viewed by 471 | Submission Open
Keywords: valorization of agricultural and food processing by-products as sources of bioactives; extraction and purification techniques for plant-derived bioactive compounds; bioactive peptides and polyphenols from underutilized or wild plant species; functional and health-promoting properties of plant-based bioactives; sustainable biorefinery approaches for bioactive recovery; In vitro and in vivo evaluation of bioactivity (e.g.; antioxidant; anti-inflammatory; antimicrobial); applications in functional foods; nutraceuticals; and cosmeceuticals; environmental and economic assessments of sustainable bioactive sourcing
(This special issue belongs to the Section Natural Products Chemistry)
Advances in Porous Organic Materials: Syntheses, Structures and Applications
edited by Tianqiong Ma, Wankai An and
submission deadline 30 Jun 2026 | Viewed by 467 | Submission Open
Keywords: porous organic materials; porous organic polymers (POPs); covalent organic frameworks (COFs); conjugated microporous polymers (CMPs); porous aromatic frameworks (PAFs); polymers of intrinsic microporosity (PIMs); hyper-cross-inked polymers (HCPs); porous organic cages
(This special issue belongs to the Section Materials Chemistry)
Applications of Porous Organic Frameworks in Environmental Remediation
edited by , Xingjie Wang and Kaikai Ma
submission deadline 30 Jun 2026 | 1 articles | Viewed by 429 | Submission Open
Keywords: porous organic frameworks (POFs); covalent organic frameworks (COFs); porous aromatic frameworks (PAFs); hydrogen-bonded organic frameworks (HOFs); environmental remediation; pollutant adsorption; catalytic degradation; gas capture and conversion; functional porous materials
(This special issue belongs to the Section Applied Chemistry)
Synthesis, Characterization and Anticancer Activities of Metal Complexes
edited by
submission deadline 30 Jun 2026 | Viewed by 423 | Submission Open
Keywords: in vitro activity; in vivo activity; metal complex; biological studies; anticancer activity; bimetallic complexes; mechanistic studies
(This special issue belongs to the Section Inorganic Chemistry)
Microbe Metabolites as Functional and Bioactive Components in Food
edited by
submission deadline 30 Jun 2026 | Viewed by 417 | Submission Open
Keywords: microbial metabolites; functional food; bioactive compounds; fermentation; gut microbiota; single-cell protein; microbial lipids; natural pigments; probiotics
Recent Advances in the Development of Innovative Anticancer Agents and Antitumor Strategies submission deadline 30 Jun 2026 | 1 articles | Viewed by 412 | Submission Open
Keywords: anticancer strategies; anticancer agents; drug design; drug development; chemical synthesis; small molecules; drug delivery; prodrugs; hybrid compounds; multitarget ligands; conjugate derivatives; polypharmacology; hybrid nanoassemblies; nanoparticles; supramolecular systems; theranostics
(This special issue belongs to the Section Medicinal Chemistry)
New Insights into Porous Carbon Materials for a Sustainable Future
edited by
submission deadline 30 Jun 2026 | Viewed by 400 | Submission Open
Keywords: porous carbon materials; biomass-derived carbon; waste-to-carbon; energy storage; carbon capture; supercapacitors; green synthesis; functionalized carbon; environmental applications
Feature Review Papers in Electrochemistry, 2nd Edition submission deadline 30 Jun 2026 | 1 articles | Viewed by 393 | Submission Open
Keywords: electrochemical science; electrochemical technology; environmental applications; new materials; energy conversion; energy storage; electrocatalysis; combined electrochemical technologies
(This special issue belongs to the Section Electrochemistry)
Novel Research and Applications of Aptasensors Based on Evolutional Selection of Aptamers
edited by , and Liling Hao
submission deadline 30 Jun 2026 | Viewed by 382 | Submission Open
Keywords: aptasensor; food contaminant analysis; environment pollutant analysis; medical analysis; point-of-care testing; nanomaterial functionalization; artificial intelligence-aided analysis; process monitoring
(This special issue belongs to the Section Analytical Chemistry)
Natural Products for Chronic Disease: Mechanisms and Applications
edited by and
submission deadline 30 Jun 2026 | Viewed by 381 | Submission Open
Keywords: natural products; chronic diseases; mechanism; herbal compound; drug delivery system; molecular modification
(This special issue belongs to the Section Natural Products Chemistry)
Biological Properties of Terpenoids submission deadline 30 Jun 2026 | Viewed by 367 | Submission Open
Keywords: terpenoids; biological activities; anticancer; anti-infectives; anti-inflammatory; antioxidant
(This special issue belongs to the Section Natural Products Chemistry)
Nicotinamide Adenine Dinucleotide (NAD) Metabolism and Related Drug Compounds (Second Edition) submission deadline 30 Jun 2026 | Viewed by 359 | Submission Open
Keywords: NAD metabolism; NAD enzymology; NAD biosynthesis; NAD degradation; pyridine drugs; niacin; vitamin B3; drug discovery; NAD-based therapeutics
(This special issue belongs to the Section Chemical Biology)
Terpenes, Steroids and Their Derivatives, 3rd Edition
edited by
submission deadline 30 Jun 2026 | Viewed by 348 | Submission Open
Keywords: terpene and steroid chemistry; biochemistry; repurposing; and practical utilization; terpene and steroid derivative synthesis; isolation and analysis of terpenes and steroids; terpene and steroid medicinal; as well as cosmetic; utilization; fluorescent labelling; bio-imaging
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