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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Polymer Materials Based on Lignocellulosic Biomass
edited by Roland El Hage and
submission deadline 30 Nov 2025 | 15 articles | Viewed by 29631 | Submission Open
Keywords: natural fibers; agricultural wastes; pre-treatments; functionalisation; sustainability
(This special issue belongs to the Section Materials Chemistry)
Applied Analytical Chemistry: Second Edition
edited by
submission deadline 30 Nov 2025 | 8 articles | Viewed by 27608 | Submission Open
Keywords: food production; forensic practice and archaeology; environmental monitoring; clinical practice; quality control in industry; analysis of plant material
(This special issue belongs to the Section Analytical Chemistry)
10th Anniversary of Green Chemistry Section submission deadline 30 Nov 2025 | 19 articles | Viewed by 27007 | Submission Open
Keywords: green catalysts; green extraction and processing; chemistry based on natural products; bio-based solvents with sub- and super-critical fluids; microwave and ultrasound; organic reaction in green solvents; bioconversion of biomass and sustainable biomaterials; creating fine chemicals and polymers from renewable resources; green nanotechnology; green analytical chemistry; green degradation process
(This special issue belongs to the Section Green Chemistry)
10th Anniversary of the Bioorganic Chemistry Section of Molecules submission deadline 30 Nov 2025 | 8 articles | Viewed by 18881 | Submission Open
Keywords: chemoenzymatic synthesis and use of enzymes in organic chemistry; enzyme inhibitors; enzyme immobilization and controlled enzyme immobilization; biocatalysis (ribozymes and catalytic antibodies); biosynthesis; combinatorial biosynthesis; biomimetic synthesis; synthetic glycobiology; immunochemical techniques; membrane chemistry; protein and small biomolecules; protein– protein interactions; protein– molecule interactions; functional proteins and peptides; peptide chemistry; biopolymers and artificial supramolecular assemblies; the organic chemistry aspects of genetic engineering; neurotoxins and neuronal receptors; molecular recognition of nucleic acids; bioactive lipids; non-natural amino acids; mass spectrometry studies on biomolecules; bioactive peptides and proteins; biological signalling
(This special issue belongs to the Section Bioorganic Chemistry)
Medicinal Value of Natural Bioactive Compounds and Plant Extracts, 3rd Edition submission deadline 30 Nov 2025 | 6 articles | Viewed by 17370 | Submission Open
Keywords: secondary plant metabolites; plant extracts; biological activity; polyphenols; alkaloids; in vitro; in vivo and study; cosmetology; ethnopharmacology; isolation and structure elucidation of plant metabolites
(This special issue belongs to the Section Natural Products Chemistry)
Functional Evaluation of Bioactive Compounds from Natural Sources, 2nd Edition submission deadline 30 Nov 2025 | 6 articles | Viewed by 17103 | Submission Open
Keywords: bioactive compounds; natural sources; functional evaluation; biological activities; health benefits; mechanisms of action; bioactivity; phytochemicals
(This special issue belongs to the Section Natural Products Chemistry)
Food Chemistry and Bioactive Compounds in Relation to Health, 2nd Edition submission deadline 30 Nov 2025 | 6 articles | Viewed by 15334 | Submission Open
Keywords: biologically active compounds; functional food ingredients; metabolic pathways; health benefits; foodborne pathogens; probiotics; chromatographic analysis; enzymes applied in food industry
(This special issue belongs to the Section Food Chemistry)
Research Progress of New Antimicrobial Drugs submission deadline 30 Nov 2025 | 9 articles | Viewed by 15276 | Submission Open
Keywords: synthesis of new antimicrobials; bioactive compounds; antimicrobial derivatives; synthetic and natural compounds; pathogens and opportunistic microbes; prevention and treatment; antibiofilm; discovery of antimicrobials
(This special issue belongs to the Section Medicinal Chemistry)
Recent Advances in the Valorization of Food, Agricultural By-Products and Waste, 2nd Edition submission deadline 30 Nov 2025 | 11 articles | Viewed by 12631 | Submission Open
Keywords: agro-food byproducts; green extraction methods; bioactive compounds; in vitro analysis; ex vivo and in vivo studies; health benefits; nutraceuticals
(This special issue belongs to the Section Green Chemistry)
Insights for Organofluorine Chemistry, 2nd Edition
edited by
submission deadline 30 Nov 2025 | 3 articles | Viewed by 11838 | Submission Open
Keywords: organofluorine compounds; fluorination; fluoroalkylation; fluorination reagents; fluoroalkylation reagents; fluorine building blocks; fluorine drugs; fluorine pesticides; fluorinated materials
(This special issue belongs to the Section Organic Chemistry)
Amphiphilic Molecules, Interfaces and Colloids: 2nd Edition
edited by and Khristo Khristov
submission deadline 30 Nov 2025 | 8 articles | Viewed by 11384 | Submission Open
Keywords: emulsions; foams; sols; gels; amphiphilic molecules; self-assembled structures; phase behavior; surface forces; intermolecular forces; adsorption; rheology; design of functionalized colloids; thin liquid films
(This special issue belongs to the Section Physical Chemistry)
Heterogeneous Catalysis for Sustainability and Carbon-Neutrality
edited by Ruiyang Qu
submission deadline 30 Nov 2025 | 10 articles | Viewed by 11046 | Submission Open
Keywords: heterogeneous catalysis; photocatalysis; electrocatalysis; catalytic materials; renewable energy; sustainable development; carbon-neutrality
(This special issue belongs to the Section Cross-Field Chemistry)
Advances in the Mass Spectrometry of Chemical and Biological Samples
edited by
submission deadline 30 Nov 2025 | 5 articles | Viewed by 10570 | Submission Open
Keywords: sample preparation; extraction; and ionization techniques; targeted and untargeted MS-based methods; high-resolution mass spectrometry (HRMS); MS-based omics; MS imaging; MS-based biomarker discovery and clinical diagnosis; MS-based drug development and toxicity monitoring; MS-based analysis of microbiome; MS in food chemistry and control; MS in forensic science; MS in cosmetic science; MS in environmental science; miniature MS systems; MS applications in nanomaterials development; MS applications in synthetic chemistry
(This special issue belongs to the Section Analytical Chemistry)
Bee Products: Recent Progress in Health Benefits Studies, 2nd Edition submission deadline 30 Nov 2025 | 4 articles | Viewed by 10454 | Submission Open
Keywords: honey bee products; bioactive compounds; biological and phamacological activity; health benefits; side effects of honey bee products
(This special issue belongs to the Section Natural Products Chemistry)
Lipids and Surfactants in Delivery Systems
edited by Agnieszka Lewińska and Marta Domżał-Kędzia
submission deadline 30 Nov 2025 | 4 articles | Viewed by 8900 | Submission Open
Keywords: delivery systems; controlled-release systems; targeted delivery systems; preparation and characterization; surfactant– lipid interactions; lipid and surfactant nanocarriers; bioavailability enhancement; nanotechnology
(This special issue belongs to the Section Nanochemistry)
Recent Advances in Supramolecular Chemistry
edited by Wen-Chao Geng
submission deadline 30 Nov 2025 | 7 articles | Viewed by 7997 | Submission Open
Keywords: supramolecular chemistry; molecular recognition; self-assembly; supramolecular materials; macrocycles
(This special issue belongs to the Section Macromolecular Chemistry)
Featured Reviews in Organometallic Chemistry, 2nd Edition
edited by
submission deadline 30 Nov 2025 | 3 articles | Viewed by 7932 | Submission Open
Keywords: organometallic chemistry; complexes; metals; metal– carbon bonding; main group metals; transition metals; lanthanides; catalysis; ligands; metal chemistry; phosphines; N-heterocyclic carbenes; bipyridines; homogeneous catalysis; cross coupling; bond activation; ancillary ligands; photoredox catalysis; asymmetric catalysis; crystallography; spectroscopy
(This special issue belongs to the Section Organometallic Chemistry)
Advanced Luminescent Materials: From Design, Synthesis, Fluorescent Mechanism to Applications
edited by Wei Chen
submission deadline 30 Nov 2025 | 4 articles | Viewed by 7917 | Submission Open
Keywords: fluorescent probes; bioimaging; biosensing; biomaterials
(This special issue belongs to the Section Nanochemistry)
Advances in Green Solvents for Analytical Chemistry: Deep Eutectic Solvents and Biosolvents submission deadline 30 Nov 2025 | 4 articles | Viewed by 7391 | Submission Open
Keywords: eutectic Solvents; biosolvents; green chemistry; microextraction techniques; environmentally friendly methods; green sample preparation; chromatography modifiers; sample preparation
(This special issue belongs to the Section Analytical Chemistry)
Synthesis and Crystal Structure of Rare-Earth Metal Compounds
edited by
submission deadline 30 Nov 2025 | 5 articles | Viewed by 7091 | Submission Open
Keywords: synthesis; crystal structure; luminescence; magnetism; catalysts; optical properties
(This special issue belongs to the Section Inorganic Chemistry)
Advanced Analytical Tools for Characterization and Quality Control of Food, Drugs, and Natural Active Ingredients, 3rd Edition submission deadline 30 Nov 2025 | 5 articles | Viewed by 6831 | Submission Open
Keywords: authentication; classification; pharmaceutical drugs; food; quality control; natural products; geographical origin; chemometrics
(This special issue belongs to the Section Analytical Chemistry)
Recent Advances in Mass Spectrometry Analysis for Medical and Pharmaceutical Applications
edited by Wojciech Piekoszewski
submission deadline 30 Nov 2025 | 3 articles | Viewed by 5956 | Submission Open
Keywords: mass spectrometry (MS); biomarkers; drug metabolism; proteomics; metabolomics; pharmaceutical analysis; personalized medicine; therapeutic drug monitoring
(This special issue belongs to the Section Analytical Chemistry)
Small Molecule Drug Discovery and Development to Face Neurodegenerative Threads submission deadline 30 Nov 2025 | 4 articles | Viewed by 5918 | Submission Open
Keywords: neurodegenerative diseases; neuroprotection; drug discovery; synthesis of pharmaceutically relevant compounds; isolation and identification of biologically active natural products; in vitro; ex vivo; and in vivo biological evaluation; molecular docking; drug repositioning
(This special issue belongs to the Section Medicinal Chemistry)
Advanced Polymer Nanocomposites for Energy Applications for a Sustainable Environment submission deadline 30 Nov 2025 | 2 articles | Viewed by 5601 | Submission Open
Keywords: polymer nanocomposites; multifunctional materials; heat storage; energy conversion; energy harvesting; thermal management of batteries; characterization; applications
(This special issue belongs to the Section Materials Chemistry)
Quantum Chemical Calculations of Molecular Reaction Processes, 2nd Edition
edited by and Shiro Koseki
submission deadline 30 Nov 2025 | 5 articles | Viewed by 4998 | Submission Open
Keywords: computational chemistry; electronic structure; MO theory; DFT calculation; reaction process; Ab initio molecular dynamics; molecular design
(This special issue belongs to the Section Computational and Theoretical Chemistry)
Extraction and Analysis of Natural Products in Food—3rd Edition submission deadline 30 Nov 2025 | 4 articles | Viewed by 4218 | Submission Open
Keywords: natural products; extraction methodologies: green impacts and sustainability  ; separation and purification techniques  ; agri-food byproducts  ; natural bioactive compounds  ; food ingredients  ; industrial application
(This special issue belongs to the Section Natural Products Chemistry)
Innovative Materials for Advanced Lithium, Sodium and Zinc Batteries: Design, Synthesis and Application
edited by Ting He
submission deadline 30 Nov 2025 | 2 articles | Viewed by 4190 | Submission Open
Keywords: functional electrode material; electrochemistry; energy storage; Li/Na/Zn-ion battery; aqueous battery
(This special issue belongs to the Section Electrochemistry)
Advances in Food Analytical Methods
edited by Yahui Guo
submission deadline 30 Nov 2025 | 4 articles | Viewed by 4104 | Submission Open
Keywords: food analysis; food component; food contaminant; food additive; functional compound; chromatography; mass spectrometry; spectroscopy; biosensor; chemometrics; AI-based approach; food safety; food authenticity; nutritional quality; food traceability
(This special issue belongs to the Section Food Chemistry)
Extraction and Antioxidant Activity of Bee Products submission deadline 30 Nov 2025 | 2 articles | Viewed by 4050 | Submission Open
Keywords: bee products; extraction; chemical composition; isolation and identification; chromatographic analysis; analytical methods; antioxidants; biologically active compounds
(This special issue belongs to the Section Natural Products Chemistry)
Advanced Materials for Photocatalytic and Photoelectrocatalytic Water-Splitting submission deadline 30 Nov 2025 | 2 articles | Viewed by 3834 | Submission Open
Keywords: photocatalysis; photoelectrocatalysis; water splitting; bandgap engineering; semiconductor materials; visible-light-driven catalysis
(This special issue belongs to the Section Materials Chemistry)
Natural-Based Sorbents for Water Remediation submission deadline 30 Nov 2025 | 4 articles | Viewed by 3366 | Submission Open
Keywords: natural sorbents; removal of organic or inorganic contaminants from water; physical and chemical characterization of the sorbent; kinetic and equilibrium sorptive tests; evaluation of thermodynamic and kinetic parameters; determination of the actual sorption mechanism
(This special issue belongs to the Section Physical Chemistry)
Advances in 2D Materials for Electrochemical Applications
edited by Le Li, Dan Zhang and
submission deadline 30 Nov 2025 | 2 articles | Viewed by 3252 | Submission Open
Keywords: electrochemistry; 2D materials and their composites; materials chemistry; energy storage and conversion; batteries; solar cells and electrocatalysis
(This special issue belongs to the Section Electrochemistry)
Functional Nanomaterials for Food Safety and Biomedicine Analysis Applications
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 3198 | Submission Open
Keywords: functional nanomaterials; biosensors; food safety; biomedicine analysis; disease diagnosis
(This special issue belongs to the Section Applied Chemistry)
Synthesis and Application of Multifunctional Nanocomposites
edited by , Yao Yuan and Lulu Xu
submission deadline 30 Nov 2025 | 1 articles | Viewed by 2780 | Submission Open
Keywords: nanocomposites; functional materials; molecules; synthesis; characterization
(This special issue belongs to the Section Nanochemistry)
Functional Crystal Materials: Challenges and Opportunities
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 2686 | Submission Open
Keywords: functional crystal materials; crystal engineering; structure-property relationship; multi stimulus responsive crystals; artificial intelligence; molecular self-assembly; meso-scale
(This special issue belongs to the Section Materials Chemistry)
Valorization of Biomass and Waste: Transforming Renewable Resources into High-Value Chemicals and Fuels
edited by
submission deadline 30 Nov 2025 | 2 articles | Viewed by 2502 | Submission Open
Keywords: thermochemical; biochemical; and hybrid conversion processes; noncatalytic; catalytic; and biocatalytic valorization pathways; platform chemicals and bio-based polymers from biomass; biofuels production (biodiesel; bioethanol; biogas; etc.); upcycling of agricultural; industrial; and municipal waste; process optimization and scale-up; novel materials derived from renewable or waste sources
(This special issue belongs to the Section Green Chemistry)
Metal Complexes: Synthesis, Characterization and Applications submission deadline 30 Nov 2025 | 2 articles | Viewed by 2333 | Submission Open
Keywords: coordination compounds; synthetic strategies; magnetic properties; optical properties; metallodrugs; catalysis
(This special issue belongs to the Section Organometallic Chemistry)
Novel Membranes and Coatings for Biomedical and Food Applications
edited by
submission deadline 30 Nov 2025 | 2 articles | Viewed by 2130 | Submission Open
Keywords: model cell membranes; biocompatible and edible coatings; bioactive compounds; nutrients; biomaterials; surface characteristics; dispersion systems
(This special issue belongs to the Section Applied Chemistry)
Advances in Anticancer Activity of Natural Products and Related Compounds
edited by
submission deadline 30 Nov 2025 | 2 articles | Viewed by 2093 | Submission Open
Keywords: natural compounds; anticancer activity; bioactive compounds; cancer therapeutics; drug resistance; synergistic effect
(This special issue belongs to the Section Natural Products Chemistry)
Inorganic Photoelectric Functional Materials: Design, Synthesis and Applications
edited by Luyi Zou
submission deadline 30 Nov 2025 | 2 articles | Viewed by 1786 | Submission Open
Keywords: photoelectric material; molecular structure; molecular composition; structural performance
(This special issue belongs to the Section Inorganic Chemistry)
Novel Antimicrobial Molecules Derived from Natural Sources submission deadline 30 Nov 2025 | 1 articles | Viewed by 1724 | Submission Open
Keywords: antibiotics; mechanism of action; plant antimicrobials; animal antimicrobials; chemical characterization; bacteriocins
(This special issue belongs to the Section Natural Products Chemistry)
Natural Bioactive Compounds from Traditional Asian Plants—Second Edition
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1459 | Submission Open
Keywords: natural product; medicinal plants; traditional medicine; bioactive molecules; crude drugs
(This special issue belongs to the Section Natural Products Chemistry)
Design, Synthesis and Evaluation of Novel Anticancer Agents, 2nd Edition submission deadline 30 Nov 2025 | 1 articles | Viewed by 1291 | Submission Open
Keywords: anticancer agents; medicinal chemistry; heterocycles; azines; azoles
(This special issue belongs to the Section Medicinal Chemistry)
Physical–Chemical Interactions and Composition–Structure–Property Modifications During Food Processing submission deadline 30 Nov 2025 | 1 articles | Viewed by 1270 | Submission Open
Keywords: structure; food; thermal properties; chemical composition
(This special issue belongs to the Section Food Chemistry)
Extraction of Plant-Derived Bioactives: Impacts on Human Health and Pharmacological Applications
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1266 | Submission Open
Keywords: plant extracts; bioactivity; pharmacology; human health; natural compounds extraction; natural compounds activity; pharmacokinetics
(This special issue belongs to the Section Natural Products Chemistry)
From Biomass to High-Value Products: Processes and Applications
edited by
submission deadline 30 Nov 2025 | 2 articles | Viewed by 1187 | Submission Open
Keywords: biomass valorization; biorefineries; green chemistry; bio-based products; catalysis; thermochemical conversion; sustainable materials
(This special issue belongs to the Section Applied Chemistry)
30th Anniversary of Molecules—Recent Advances in Ultrasound Chemistry submission deadline 30 Nov 2025 | Viewed by 491 | Submission Open
Keywords: ultrasound; hydrodynamic cavitation; sonochemistry; sonocrystallisation; sono processing; sono extraction; applications in chemical engineering
(This special issue belongs to the Section Ultrasound Chemistry)
Phytochemicals from Agricultural Production By-Products and Wastes and Their Re-Use submission deadline 30 Nov 2025 | Viewed by 348 | Submission Open
Keywords: phytochemical recovery; agricultural by-products; sustainable valorization; circular economy; bioactive compounds; biorefinery processes
(This special issue belongs to the Section Natural Products Chemistry)
Innovative and Sustainable Enzymatic Strategies Towards Chiral Products
edited by Enikő Forró and
submission deadline 30 Nov 2025 | Viewed by 344 | Submission Open
Keywords: dynamic kinetic resolution; enzyme catalyzed transformation; green technology; kinetic resolution; pharmaceutically important enantiomers; sequential kinetic resolution; sustainable enzymatic strategy
(This special issue belongs to the Section Green Chemistry)
Photo- and Electro-Catalysts for Carbon Neutrality
edited by Niantzu Suen and Jianhua Hou
submission deadline 30 Nov 2025 | Viewed by 313 | Submission Open
Keywords: photocatalyst; electrocatalyst; hydrogen evolution reaction; CO2 reduction; carbon neutrality; heterogeneous catalyst; renewable energy
(This special issue belongs to the Section Materials Chemistry)
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