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Medicina publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Outcomes After Surgical Treatment of Pelvic Organ Prolapse

edited by Justina Kačerauskienė and Roger Roman Dmochowski

submission deadline 30 Apr 2026 | 1 articles | Viewed by 947 | Submission Open

Keywords: pelvic organ prolapse; surgery; recurrence; vaginal hysterectomy; sacrocolpopexy; Manchester operation; sacrospinous fixation; native tissue

(This special issue belongs to the Section Obstetrics and Gynecology)

Underserved Ophthalmology Healthcare

edited by

Jay Chhablani

and Anindya Samanta

submission deadline 30 Apr 2026 | 2 articles | Viewed by 831 | Submission Open

Keywords: underserved ophthalmology; unsheltered ophthalmology; homeless ophthalmology; telemedicine; mobile ophthalmology clinic; free ophthalmology clinic

(This special issue belongs to the Section Ophthalmology)

Physiotherapy for Head and Neck Cancer

edited by

Ernesto Anarte-Lazo

submission deadline 30 Apr 2026 | 1 articles | Viewed by 776 | Submission Open

Keywords: physiotherapy; head and neck cancer; neuromusculoskeletal impairments

(This special issue belongs to the Section Oncology)

Recent Advances in Otological Diseases

edited by

Andrea Frosolini

submission deadline 30 Apr 2026 | Viewed by 239 | Submission Open

Keywords: otology; hearing loss; tinnitus; otitis media; vestibular disorders; diagnostic methods; treatment; surgery; epidemiology; medical devices

Innovations in Sports Injury Prevention and Rehabilitation

edited by

Sofia Xergia

and

Nikolaos I. Liveris

submission deadline 30 Apr 2026 | Viewed by 146 | Submission Open

Keywords: sports injury rehabilitation; injury prevention; risk factors; return-to-play (RTP) criteria; biomechanical analysis; sports psychology; surgical intervention methods; ligament repair; joint reconstruction; physical therapy and rehabilitation

(This special issue belongs to the Section Orthopedics)

Trauma-Associated Tinnitus and Hearing Loss

edited by

Sebastian Cozma

and Madalina Gabriela Georgescu

submission deadline 30 Apr 2026 | Viewed by 126 | Submission Open

Keywords: acute tinnitus; chronic tinnitus; tinnitus related quality of life; traumatic brain injury; cochlear concussion; third window syndrome; tinnitus management

(This special issue belongs to the Section Neurology)

Recent Breakthroughs in Orthodontic Treatment

edited by

Saverio Cosola

and

Michela Boccuzzi

submission deadline 30 Apr 2026 | Viewed by 93 | Submission Open

Keywords: orthodontics; digital orthodontics; artificial intelligence; clear aligners; biomaterial; skeletal anchorage; CAD– CAM technology; customized appliances; oral health

(This special issue belongs to the Section Dentistry and Oral Health)

Application of Endoscopy in Gastrointestinal Disease

edited by

Irina Girleanu

Cristina Muzica

and Ana Maria Trofin

submission deadline 30 Apr 2026 | Viewed by 87 | Submission Open

Keywords: gastrointestinal endoscopy; colonoscopy; colorectal cancer screening; endoscopic therapy; EMR and ESD; artificial intelligence in endoscopy; upper GI endoscopy; GI bleeding; image-enhanced endoscopy; therapeutic endoscopy

(This special issue belongs to the Section Gastroenterology & Hepatology)

Clinical Diagnosis and Management of Cardiovascular Disease

edited by Federica Marzano,

Paola Gargiulo

and Stefania Paolillo

submission deadline 30 Apr 2026 | Viewed by 79 | Submission Open

Keywords: cardiovascular disease; clinical diagnosis; risk stratification; biomarkers; cardiovascular imaging; personalized medicine; therapeutic management; preventive cardiology

(This special issue belongs to the Section Cardiology)

Advances in Laparoscopic Surgery

edited by

Mario Palumbo

and

Luigi Della Corte

submission deadline 30 Apr 2026 | Viewed by 76 | Submission Open

Keywords: laparoscopic surgery; minimally invasive gynecology; robotic-assisted surgery intraoperative ultrasound; hysteroscopy; gynecologic oncology; endometriosis; benign gynecology

(This special issue belongs to the Section Surgery)

New Insights into Heart Failure Management and Treatment

edited by

Alejandro N. Barbagelata

and Edgardo J. Kaplinsky

submission deadline 30 Apr 2026 | Viewed by 67 | Submission Open

Keywords: heart failure; cardiovascular disease; treatment advances; management strategies; personalized medicine; clinical guidelines; diagnostic innovations; multidisciplinary care; emerging therapies; patient outcomes

(This special issue belongs to the Section Cardiology)

Tendon Injury and Reconstruction

edited by

Marisa Megna

, Maurizio Ranieri and

Riccardo Marvulli

submission deadline 30 Apr 2026 | Viewed by 52 | Submission Open

Keywords: tendon injuries; tendon function; pain management; physical therapy; tendon rehabilitation; shock waves therapy; health promotion; pain perception; biological terapies; tendon surgery

(This special issue belongs to the Section Orthopedics)

Advances in the Prevention and Treatment of Mycobacterial Diseases

edited by

Selvakumar Subbian

submission deadline 30 Apr 2026 | Viewed by 52 | Submission Open

Keywords: mycobacterium tuberculosis; non-tuberculous mycobacteria; tuberculosis; granuloma; pathogenesis; antimicrobial drug resistance; molecular diagnostics; host-directed therapy; BCG vaccine; immune response; host– pathogen interactions

(This special issue belongs to the Section Infectious Disease)

Advances in Total Hip Arthroplasty: From Diagnosis to Treatment

edited by

Thomas W. Wainwright

and

Rob Middleton

submission deadline 30 Apr 2026 | Viewed by 48 | Submission Open

Keywords: total hip arthroplasty; preoperative planning and imaging; robotics and navigation; patient-specific instrumentation; smart prostheses; augmented reality in surgery; digital rehabilitation; multidisciplinary care

(This special issue belongs to the Section Orthopedics)

The Role of Arthroscopy in Modern Orthopedics

edited by

Jae-Sung Yoo

submission deadline 30 Apr 2026 | Viewed by 47 | Submission Open

Keywords: arthroscopy; minimally invasive surgery; soft tissue preservation; high-resolution imaging; surgical precision; small joint arthroscopy; special condition arthroscopy

(This special issue belongs to the Section Orthopedics)

Recent Progress in Cardiac Surgery

edited by

Giuseppe Nasso

and

Walter Vignaroli

submission deadline 30 Apr 2026 | Viewed by 47 | Submission Open

Keywords: mitral valve; TAVI; aortic valve; coronary artery bypass; ascending aorta; valve sparing; innovation in cardiac surgery; ventricular assist device; ECMO; cardiac support

(This special issue belongs to the Section Cardiology)

Immune Checkpoint Inhibitors for Thoracic Malignant Tumors

edited by

Hisao Imai

submission deadline 30 Apr 2026 | Viewed by 43 | Submission Open

Keywords: immune checkpoint inhibitors; thoracic malignancies; non-small cell lung cancer; small cell lung cancer; malignant pleural mesothelioma; PD-1/PD-L1 blockade; combination immunotherapy; biomarkers; tumor microenvironment; resistance mechanisms

(This special issue belongs to the Section Oncology)

Psychosis Mechanisms and Interventions

edited by

Giorgia Varallo

and

Valentina Baldini

submission deadline 30 Apr 2026 | Viewed by 38 | Submission Open

Keywords: psychosis; neurobiology; early intervention; cognitive dysfunction; trauma; dopamine; sleep disturbances; antipsychotics; digital psychiatry; precision medicine

(This special issue belongs to the Section Psychiatry)

Perioperative Medicine: Optimizing Outcomes Through Anesthesia

edited by

Lucía Valencia

submission deadline 30 Apr 2026 | Viewed by 36 | Submission Open

Keywords: anesthesia; analgesia; enhanced recovery after surgery; intensive care unit

(This special issue belongs to the Section Intensive Care/ Anesthesiology)

Updates on Allergies and Immunodeficiencies

edited by

Carmen Panaitescu

and

Maria Roxana Buzan

submission deadline 30 Apr 2026 | Viewed by 36 | Submission Open

Keywords: allergy; immunodeficiency; allergens; cross-reactivity; molecular allergy diagnostics; immunotherapy; precision medicine; exposome

(This special issue belongs to the Section Hematology and Immunology)

Recent Advances in Autoimmune Rheumatic Diseases—3rd Edition

edited by

Diana Mieliauskaitė

submission deadline 30 Apr 2026 | Viewed by 33 | Submission Open

Keywords: autoimmune rheumatic diseases; rheumatoid arthritis; systemic lupus erythematosus; Sjogren’ s disease; systemic scleroderma; psoriatic arthritis; mixed connective tissue disease; ankylosing spondylitis; vasculitides; juvenile arthritis; rare autoimmune rheumatic diseases

(This special issue belongs to the Section Hematology and Immunology)

An Update to the Epidemiology, Diagnostic Challenges, and Molecular Bases of Nonalcoholic Fatty Liver Disease: 2nd Edition

edited by

Galileo Escobedo

submission deadline 30 Apr 2026 | Viewed by 33 | Submission Open

Keywords: fatty liver disease; steatohepatitis; fibrosis; COVID-19 lockdown; insulin resistance; metabolic syndrome; T cell; macrophage; computed tomography; magnetic resonance imaging

(This special issue belongs to the Section Gastroenterology & Hepatology)

Advances in Reproductive Health

edited by

Anca Huniadi

submission deadline 1 May 2026 | Viewed by 185 | Submission Open

Keywords: in vitro fertilization; PGT-A; non-invasive embryo testing; chronic endometritis; embryo culture; aneuploidy; artificial intelligence

(This special issue belongs to the Section Obstetrics and Gynecology)

Hematologic Malignancies: Diagnosis, Prognosis and Management

edited by Ádám Jona and

Zsófia Miltényi

submission deadline 1 May 2026 | Viewed by 52 | Submission Open

Keywords: malignant lymphoma; treatment; prognostication; stem cell transplantation; cellular therapy

(This special issue belongs to the Section Oncology)

Bariatric Surgery and Postoperative Management

edited by

Adam Abu Abeid

submission deadline 1 May 2026 | Viewed by 43 | Submission Open

Keywords: bariatric surgery; metabolic surgery; obesity treatment; postoperative management; revisional surgery; nutritional outcomes; complications; weight regain; comorbidity resolution; long-term follow-up

(This special issue belongs to the Section Surgery)

Optimizing Athlete Health and Performance: Multidisciplinary Perspectives in Sports Medicine

edited by

Carlos Braga

and

Júlio A. Costa

submission deadline 1 May 2026 | Viewed by 41 | Submission Open

Keywords: sports medicine; athlete health; performance optimization; injury prevention; multidisciplinary approaches; rehabilitation; nutrition in sports; wearable technologies; preventive medicine; sports psychology

Diagnosis, Management, and Treatment of Hearing Loss

edited by

Francesco Ciodaro

and

Daniele Portelli

submission deadline 10 May 2026 | Viewed by 44 | Submission Open

Keywords: hearing loss; otology; auditory rehabilitation; hearing aids; cochlear implants; regenerative medicine; precision audiology; artificial intelligence; tele-audiology; hearing health

Diabetic Retinopathy: Advances in Diagnosis and Therapeutic Strategies

edited by

Rossella D'Aloisio

and Marco Rocco Pastore

submission deadline 10 May 2026 | Viewed by 35 | Submission Open

Keywords: diabetes mellitus; diabetic retinopathy; diabetic macular edema; retinal imaging; anti-vascular endothelial growth factor injections; dexamethasone implant; vitreoretinal surgery; photocoagulation laser; diabetic eye-screening program; artificial intelligence

(This special issue belongs to the Section Ophthalmology)

Perioperative Care and Surgical Techniques in Colorectal Cancer

edited by

Giulia Turri

and

Raffaele De Luca

submission deadline 10 May 2026 | Viewed by 25 | Submission Open

Keywords: colorectal cancer; laparoscopy; robotic surgery; minimally invasive surgery; perioperative care; enhanced recovery after surgery; prehabilitation

(This special issue belongs to the Section Surgery)

Ophthalmology, Environment, and Lifestyle: New Pathways in Diagnosis and Treatment

edited by Jesús Merayo-Lloves and Rodrigo Martin Torres

submission deadline 15 May 2026 | 2 articles | Viewed by 790 | Submission Open

Keywords: vision science; ophthalmology; environment; lifestyle; aging

(This special issue belongs to the Section Ophthalmology)

Clinical Diagnosis and Treatment of Osteoporosis and Fractures

edited by Nicolas Martinez-Velilla,

Bernardo Abel Cedeño-Veloz

and

Jose Manuel Cancio-Trujillo

submission deadline 15 May 2026 | Viewed by 119 | Submission Open

Keywords: osteoporosis; fragility fractures; bone mineral density (DXA); FRAX score; bone turnover markers; precision medicine; artificial intelligence; proteomic biomarkers; anabolic and antiresorptive therapies; integrated care for fracture patients

(This special issue belongs to the Section Orthopedics)

Advances in Use of PET-CT Imaging in Disease Diagnosis

edited by Ana María García-Vicente and

Edel Noriega-Álvarez

submission deadline 15 May 2026 | Viewed by 65 | Submission Open

Keywords: PET-CT; molecular imaging; diagnostic imaging; radiotracers; oncology; inflammation and infection; neurology; cardiovascular imaging; artificial intelligence in imaging; precision medicine

Translating CBT for OCD into Practice: Modalities, Effectiveness, and Implementation

edited by

Keiichiro Mukai

and Bethany May Wootton

submission deadline 15 May 2026 | Viewed by 39 | Submission Open

Keywords: obsessive– compulsive disorder (OCD); cognitive behavioral therapy (CBT); treatment effectiveness; stepped care; low-intensity CBT with ICT (e.g.; apps; online programs); high-intensity CBT (e.g.; inpatient; residential); access to care; therapist variation; cost-effectiveness; healthcare implementation

(This special issue belongs to the Section Psychiatry)

Updates on Chronic Heart Failure and Hypertension

edited by

Ioannis Leontsinis

and

Eleni Manta

submission deadline 15 May 2026 | Viewed by 6 | Submission Open

Keywords: hypertension; heart failure; pathophysiology; device therapy; treatment; research; biomarkers

(This special issue belongs to the Section Cardiology)

Advances in Thoracic Surgery and Lung Cancer Treatment

edited by Seyer Safi and Katrin Welcker

submission deadline 15 May 2026 | Viewed by 5 | Submission Open

Keywords: lung cancer; hybrid operation; one-stop shop; segmentectomy

(This special issue belongs to the Section Pulmonology)

Combined Anterior Cruciate Ligament Reconstruction and Lateral Augmentation

edited by Theofylaktos Kyriakidis and Dimitrios Koulalis

submission deadline 15 May 2026 | Viewed by 5 | Submission Open

Keywords: anterior cruciate ligament reconstruction (ACLR); anterolateral ligament reconstruction; lateral extra-articular tenodesis; anterolateral rotatory instability; knee instability; clinical outcomes

(This special issue belongs to the Section Orthopedics)

New Insights into Neurodevelopmental Biology and Disorders

edited by

Rekha Jagadapillai

submission deadline 20 May 2026 | 3 articles | Viewed by 8262 | Submission Open

Keywords: neurodevelopment; neurodevelopmental biology; neurodevelopmental disorders; autism spectrum disorders (ASDs); down syndrome; ADHD; cerebral palsy; learning disability

(This special issue belongs to the Section Neurology)

Intracranial Aneurysms, Subarachnoid Hemorrhage and Delayed Cerebral Ischemia

edited by Leszek Michał Sagan and

Tomasz Klepinowski

submission deadline 20 May 2026 | 3 articles | Viewed by 5622 | Submission Open

Keywords: intracranial aneurysm; subarachnoid hemorrhage; vasospasm; delayed cerebral ischemia; stroke; embolization; coiling; clipping

(This special issue belongs to the Section Neurology)

Chronic Rhinosinusitis with Nasal Polyps: Latest Trends in Diagnosis and Treatment

edited by

Bruno Galletti

and

Cosimo Galletti

submission deadline 20 May 2026 | 2 articles | Viewed by 2698 | Submission Open

Keywords: chronic rhinosinusitis with nasal polyps; real-word evidence; otorhinolaryngology; rhinology; quality of life; therapeutic advances; monoclonal antibodies

(This special issue belongs to the Section Surgery)

Atrial Fibrillation and Heart Failure Management

edited by Erika Bertella

submission deadline 20 May 2026 | 1 articles | Viewed by 618 | Submission Open

Keywords: heart failure; cardiac magnetic resonance; cardiac computed tomography; echocardiography; atrial fibrillation; electrophysiology; surgery

(This special issue belongs to the Section Cardiology)

Anesthesiology, Resuscitation, and Pain Management

edited by

Diana Cimpoesu

, Ovidiu-Horea Bedreag and Mihai Octavian Botea

submission deadline 20 May 2026 | Viewed by 202 | Submission Open

Keywords: anesthesiology; resuscitation; pain medicine; general anesthesia; regional anesthesia; emergency medicine; perioperative anesthesia

(This special issue belongs to the Section Intensive Care/ Anesthesiology)

Innovations and Challenges in Thoracic Surgery: Present and Future Directions

edited by Servet Bölükbas and Konstantinos Grapatsas

submission deadline 20 May 2026 | Viewed by 75 | Submission Open

Keywords: thoracic surgery; lung cancer; pulmonary metastasectomy; mesothelioma; lung volume reduction surgery; minimally invasive surgery (VATS/ RATS); enhanced recovery after surgery (ERAS) protocols; multidisciplinary care; surgical oncology; postoperative outcomes

(This special issue belongs to the Section Surgery)

Orthopaedic Surgery: Exploring the Nonoperative Predictors of Surgical Success

edited by Mohammad Daher

submission deadline 20 May 2026 | Viewed by 24 | Submission Open

Keywords: orthopaedic surgery; surgical outcomes; nonoperative predictors; patient-reported outcomes; preoperative assessment; risk stratification; functional recovery; comorbidities; mental health in surgery; predictive modelling

(This special issue belongs to the Section Orthopedics)

Navigating from Cancer to Urolithiasis and Urinary Tract Infections: Updates in Diagnosis and Emerging Treatment Strategies in Modern Urology

edited by Razvan-Ionut Popescu

submission deadline 20 May 2026 | Viewed by 20 | Submission Open

Keywords: urolithiasis; urinary tract infections; prostate cancer; bladder cancer

(This special issue belongs to the Section Urology & Nephrology)

Advances in Diagnosis, Treatment, and Prognosis in Glomerular Diseases

edited by Dimitrios I. Petras and

Aglaia Chalkia

submission deadline 20 May 2026 | Viewed by 18 | Submission Open

Keywords: glomerular diseases; IgA nephropathy; membranous nephropathy; nephrotic syndrome; ANCA-associated vasculitis; lupus nephritis; B-cell; complement; kidney prognosis

(This special issue belongs to the Section Urology & Nephrology)

Prenatal Diagnosis: Current Challenges and Future Perspectives

edited by Yaron Zalel, Kristiina Rull and

Natalija Vedmedovska

submission deadline 20 May 2026 | Viewed by 18 | Submission Open

Keywords: prenatal diagnosis; non-invasive prenatal testing; fetal imaging; genomic medicine; multiomics; artificial intelligence in prenatal care; maternal– fetal health

(This special issue belongs to the Section Obstetrics and Gynecology)

Bronchiectasis

edited by Bryan A. Garcia and Kadambari Vijaykumar

submission deadline 20 May 2026 | Viewed by 12 | Submission Open

Keywords: bronchiectasis; cystic fibrosis (CF); allergic bronchopulmonary aspergillosis (ABPA); nontuberculous mycobacteria (NTM); aero-digestive disease; primary ciliary dyskinesia (PCD); mucolytics; pseudomonas aeruginosa; combined variable immunodeficiency (CVID); innate and adaptive airway immune responses

(This special issue belongs to the Section Pulmonology)

Recent Advances in Cardiovascular Surgery

edited by Massimo Baudo and

Lorenzo Di Bacco

submission deadline 25 May 2026 | Viewed by 40 | Submission Open

Keywords: cardiac surgery; surgical outcomes; heart valves; cabg; left atrial appendage; aortic diseases; heart failure; new technologies

(This special issue belongs to the Section Cardiology)

Personal and Pervasive Health Care for the Elderly

edited by

Yupin Aungsuroch

submission deadline 25 May 2026 | Viewed by 34 | Submission Open

Keywords: pervasive health care; personalized medicine; elderly care; wearable and ambient sensors; smart homes; telemedicine; assistive robotics; AI in health care; cognitive health; gerontechnology

(This special issue belongs to the Section Epidemiology & Public Health)

Updates on Risk Factors and Prevention of Coronary Artery Disease

edited by