Recent Advances in Diagnosis and Therapy of Inflammatory Skin Diseases

Dear Colleagues,

Inflammatory skin diseases represent a significant global health burden, affecting millions of patients worldwide and substantially impacting quality of life. These immune-mediated conditions, including psoriasis, atopic dermatitis, hidradenitis suppurativa, vitiligo, and other dermatoses, have historically posed diagnostic and therapeutic challenges. However, recent years have witnessed transformative advances that are reshaping clinical practice and patient outcomes.

Diagnostic innovation has been accelerated by the integration of artificial intelligence and machine learning applications, enabling more accurate disease classification, severity assessment, and outcome prediction. Novel imaging modalities, biomarker discovery, and digital health technologies are revolutionizing clinical evaluation and monitoring strategies. Concurrently, the therapeutic landscape has expanded dramatically with targeted biologic agents, small molecule inhibitors (including JAK inhibitors), and emerging gene therapies, offering unprecedented treatment options for patients with moderate-to-severe disease.

We are pleased to invite you to contribute to this Special Issue, which aims to showcase cutting-edge research across the translational spectrum of inflammatory skin diseases.

This Special Issue aims to provide a comprehensive overview of recent advances in the diagnosis and treatment of inflammatory skin diseases, aligning with Medicina's scope of publishing high-quality clinical and translational research. By bringing together innovative diagnostic tools, breakthrough therapeutic strategies, and mechanistic insights, this collection will serve as a valuable resource for clinicians, researchers, and healthcare professionals seeking to optimize patient care. The integration of artificial intelligence in dermatology represents a particularly timely focus area, reflecting the rapid technological transformation of our field.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:

• Novel diagnostic technologies and artificial intelligence applications in inflammatory skin diseases;
• Biomarker discovery and validation for disease diagnosis, prognosis, and treatment response;
• Advances in biologic therapies for psoriasis, atopic dermatitis, and other inflammatory dermatoses;
• JAK inhibitors and small-molecule therapeutics in inflammatory skin conditions;
• Precision medicine approaches and personalized treatment strategies;
• Digital health technologies and telemedicine in dermatology;
• Comparative effectiveness research and real-world evidence studies;
• Mechanisms of disease pathogenesis and therapeutic targets;
• Treatment of refractory or difficult-to-treat inflammatory skin diseases;
• Health outcomes research and quality of life assessments;
• Emerging therapies, including gene therapy and microbiome-based interventions;
• Pediatric inflammatory skin diseases: diagnosis and management;
• Combination therapy strategies and treatment optimization.

We look forward to receiving your contributions.

Dr. Neil Kunal Jairath
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.