Recent Advances in Autoimmune Rheumatic Diseases—3rd Edition

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Hematology and Immunology".

Deadline for manuscript submissions: 30 April 2026 | Viewed by 110

Special Issue Editor


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Guest Editor
Department of Personalised Medicine, State Research Institute Centre for Innovative Medicine, Vilnius, Lithuania
Interests: autoimmunity; Sjogren’s disease; non-autoimmune/autoimmune epithelitis; sicca syndrome; saliva; microbiota; personalized medicine
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Special Issue Information

Dear Colleagues,

Autoimmune rheumatic diseases represent the leading cause of disability worldwide, with major financial and social consequences across cultures. The number of people suffering from them is increasing, especially in more economically developed countries. Autoimmune rheumatic diseases comprise a group of diseases characterised by heterogeneous clinical, laboratory, and immunological manifestations. Their pathogenesis is not fully understood, but recent research recognises that the pathogenesis of autoimmune rheumatic diseases is multifactorial, emphasizing the need for patient-centred collaboration between clinicians and researchers.

This Special Issue will focus on the latest advances in autoimmune rheumatic diseases, with the aim of significantly contributing to clinical practice, improving public health, and sharing up-to-date information on the latest advances in autoimmune rheumatic diseases. We invite you to submit your original research and review articles to this Special Issue.

Dr. Diana Mieliauskaitė
Guest Editor

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Keywords

  • autoimmune rheumatic diseases
  • rheumatoid arthritis
  • systemic lupus erythematosus
  • Sjogren’s disease
  • systemic scleroderma
  • psoriatic arthritis
  • mixed connective tissue disease
  • ankylosing spondylitis
  • vasculitides
  • juvenile arthritis
  • rare autoimmune rheumatic diseases

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Published Papers (1 paper)

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Review

15 pages, 614 KB  
Review
Oral Manifestations of Sjögren’s Syndrome: Recognition, Management, and Interdisciplinary Care
by Shu-Cheng Liu, Ming-Chi Lu and Malcolm Koo
Medicina 2026, 62(1), 5; https://doi.org/10.3390/medicina62010005 - 19 Dec 2025
Abstract
Background and Objectives: Sjögren’s syndrome (SS) causes destructive salivary gland dysfunction with substantial oral morbidity. To synthesize practical, evidence-based approaches for early recognition, initial oral management, and timely referral to dental care. Materials and Methods: Narrative review of English-language literature from [...] Read more.
Background and Objectives: Sjögren’s syndrome (SS) causes destructive salivary gland dysfunction with substantial oral morbidity. To synthesize practical, evidence-based approaches for early recognition, initial oral management, and timely referral to dental care. Materials and Methods: Narrative review of English-language literature from the Web of Science Core Collection and PubMed, prioritizing systematic reviews, randomized trials, and consensus guidelines. Results: Early oral signs include rapid multifocal root and cervical caries, burning sensations, and rising dental treatment needs. Unstimulated whole saliva ≤ 0.1 mL/min supports significant hypofunction and complements the 2016 ACR/EULAR criteria. Preventive care should combine dietary counseling, salivary stimulation, and topical remineralization. Adjuncts include high-fluoride toothpaste, biomimetic hydroxyapatite dentifrices, and casein phosphopeptide–amorphous calcium phosphate (CPP-ACP). However, evidence for fluoride varnish in SS remains mixed. Pharmacologic sialogogues require screening for contraindications. Conclusions: Embedding oral screening, simple salivary metrics, and a structured referral pathway into rheumatology visits can reduce preventable tooth loss and improve comfort, function, and treatment adherence. Full article
(This article belongs to the Special Issue Recent Advances in Autoimmune Rheumatic Diseases—3rd Edition)
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