Advances in the Prevention and Treatment of Mycobacterial Diseases

Dear Colleagues,

Mycobacterial diseases, including tuberculosis (TB) and infections caused by non-tuberculous mycobacteria (NTM), represent a persistent global health challenge. While TB remains a leading cause of infectious mortality, NTM infections are increasingly prevalent, particularly among immunocompromised individuals and those with chronic pulmonary conditions. The immunological complexity of these diseases, coupled with diagnostic and therapeutic limitations, underscores the urgent need for deeper scientific inquiry. Recent advances in molecular diagnostics, imaging, and host-directed therapies have begun to reshape the clinical landscape. Studies on granuloma biology, fibrosis, and immune gene polymorphisms (e.g., TLRs, ADAM17) have provided new insights into host–pathogen interactions. However, the emergence of multidrug-resistant strains, biofilm formation, and limited vaccine efficacy continue to hinder progress. Moreover, overlapping clinical presentations between TB and NTM complicate diagnosis and treatment, especially in resource-limited settings.

With due recognition of the gaps in our understanding of host–pathogen interactions, drug resistance, and treatment of mycobacterial infection, the Editorial Board of Medicina has decided to bring out a Special Issue titled “Advances in the Prevention and Treatment of Mycobacterial Diseases”. This Special Issue, edited by Dr. Selvakumar Subbian, aims to consolidate cutting-edge research that advances our immunological understanding of mycobacterial diseases and informs innovative strategies for their diagnosis, prevention, and therapy.

We invite original research, reviews, and perspectives that explore immune mechanisms, host–pathogen dynamics, novel therapeutics, and translational approaches. Interdisciplinary contributions bridging immunology, microbiology, and clinical science are especially encouraged. The last day for submission for all contributions to the Special Issue is 30 April 2026.

Dr. Selvakumar Subbian
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the Special Issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.