Advances in the Prevention and Treatment of Mycobacterial Diseases
A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Infectious Disease".
Deadline for manuscript submissions: 30 April 2026 | Viewed by 16
Special Issue Editor
Interests: cytokine storm and type i interferon response in COVID-19 pathogenesis; mycobacterial infections; host directed therapy; tuberculosis; rabbit model; animal models; human pulmonary tb
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Mycobacterial diseases, including tuberculosis (TB) and infections caused by non-tuberculous mycobacteria (NTM), represent a persistent global health challenge. While TB remains a leading cause of infectious mortality, NTM infections are increasingly prevalent, particularly among immunocompromised individuals and those with chronic pulmonary conditions. The immunological complexity of these diseases, coupled with diagnostic and therapeutic limitations, underscores the urgent need for deeper scientific inquiry. Recent advances in molecular diagnostics, imaging, and host-directed therapies have begun to reshape the clinical landscape. Studies on granuloma biology, fibrosis, and immune gene polymorphisms (e.g., TLRs, ADAM17) have provided new insights into host–pathogen interactions. However, the emergence of multidrug-resistant strains, biofilm formation, and limited vaccine efficacy continue to hinder progress. Moreover, overlapping clinical presentations between TB and NTM complicate diagnosis and treatment, especially in resource-limited settings.
With due recognition of the gaps in our understanding of host–pathogen interactions, drug resistance, and treatment of mycobacterial infection, the Editorial Board of Medicina has decided to bring out a Special Issue titled “Advances in the Prevention and Treatment of Mycobacterial Diseases”. This Special Issue, edited by Dr. Selvakumar Subbian, aims to consolidate cutting-edge research that advances our immunological understanding of mycobacterial diseases and informs innovative strategies for their diagnosis, prevention, and therapy.
We invite original research, reviews, and perspectives that explore immune mechanisms, host–pathogen dynamics, novel therapeutics, and translational approaches. Interdisciplinary contributions bridging immunology, microbiology, and clinical science are especially encouraged. The last day for submission for all contributions to the Special Issue is 30 April 2026.
Dr. Selvakumar Subbian
Guest Editor
Manuscript Submission Information
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Keywords
- mycobacterium tuberculosis
- non-tuberculous mycobacteria
- tuberculosis
- granuloma
- pathogenesis, Antimicrobial drug resistance
- molecular diagnostics
- host-directed therapy
- BCG vaccine
- immune response, host–pathogen interactions
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