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Medicina publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in the Diagnosis and Treatment of Type 2 Diabetes Mellitus

edited by

Bogdan Timar

, Romulus Timar and

Adina Braha

submission deadline 30 Dec 2025 | 3 articles | Viewed by 7108 | Submission Open

Keywords: novel diagnostic markers of type 2 diabetes and its complications; continuous glucose monitoring in type 2 diabetes; time in tight range in type 2 diabetes; nanotechnology in type 2 diabetes; SGLT-2 inhibitors; GLP-1 receptor agonists; dual GIP/GLP-1 receptor agonists; next-generation GLP-1/GIP/glucagon triple agonists; amylin analogues; bariatric surgery in managing type 2 diabetes and obesity; gut microbiota in type 2 diabetes; liposome; monoclonal antibodies; Lp a; MASH in type 2 diabetes; differentiated thyroid cancer and pancreatic cancer in type 2 diabetes mellitus

(This special issue belongs to the Section Endocrinology)

Recent Advances in Gynecological Surgery

edited by

Felice Sorrentino

submission deadline 30 Dec 2025 | 3 articles | Viewed by 1659 | Submission Open

Keywords: hysteroscopy; laparoscopy; robotics; vNOTES; laser; gynecological surgery; resectoscope

(This special issue belongs to the Section Obstetrics and Gynecology)

Psychiatric Comorbidities and Substance Use Among Individuals with Physical Health Issues and Chronic Diseases

edited by

Jagdish Khubchandani

submission deadline 30 Dec 2025 | Viewed by 63 | Submission Open

Keywords: psychiatry; substance use; chronic disease; physical health issues; addiction; mental health; health outcomes; alcohol; tobacco; and other drug use; healthcare utilization

Clinical Applications of Modern Technologies in Neurosurgery and Spine Surgery

edited by

Mirza Pojskić

Christopher Nimsky

and

Miriam Bopp

submission deadline 31 Dec 2025 | 7 articles | Viewed by 17042 | Submission Open

Keywords: modern technologies; neuronavigation; augmented reality; virtual reality; robotics; endoscopy; tumor treating fields; tumor biology; intraoperative ultrasound; intraoperative computed tomography; intraoperative magnetic resonance imaging; neuroradiology; neurosurgery; spine surgery

(This special issue belongs to the Section Neurology)

Advances in Soft and Hard Tissue Management Around Dental Implants

edited by

Roberto Rossi

and

Fabrizio Bambini

submission deadline 31 Dec 2025 | 7 articles | Viewed by 12813 | Submission Open

Keywords: dental implants; soft tissue around implants; bone regeneration; prosthetic implants; esthetic implants

(This special issue belongs to the Section Dentistry and Oral Health)

Chronic Inflammatory Skin Diseases: Where We Are and Where We Are Going: 2nd Edition

edited by

Fabrizio Martora

and

Matteo Megna

submission deadline 31 Dec 2025 | 6 articles | Viewed by 7653 | Submission Open

Keywords: psoriasis; atopic dermatitis; hidradenitis suppurativa; skin inflammatory disease

(This special issue belongs to the Section Dermatology)

Physical Therapy: A New Perspective

edited by

Manuel González-Sánchez

and Laura Zlibinaite

submission deadline 31 Dec 2025 | 4 articles | Viewed by 4591 | Submission Open

Keywords: physical therapy; physiotherapy; therapeutic exercise; rehabilitation; exercise prescription; treatment techniques; musculoskeletal health; movement impairments; functional abilities; innovation

(This special issue belongs to the Section Sports Medicine and Sports Traumatology)

New Insights into Plastic and Reconstructive Surgery

edited by

Francesco De Francesco

and Michele Riccio

submission deadline 31 Dec 2025 | 4 articles | Viewed by 4044 | Submission Open

Keywords: microsurgery; regenerative medicine; tissue engineering; robotic surgery; biomimetic materials; aesthetic surgery; wound healing; 3D printing; reconstructive techniques; psychological impacts

(This special issue belongs to the Section Surgery)

Diabetes and Obesity: What Is New in 2025

edited by

Manfredi Rizzo

and

Ali Abbas Rizvi

submission deadline 31 Dec 2025 | 3 articles | Viewed by 3962 | Submission Open

Keywords: diabetes; obesity; metabolic syndrome; cardiovascular disease; insulin resistance

(This special issue belongs to the Section Endocrinology)

Diagnosis and Treatment of Urologic Oncology

edited by

Juan Gómez Rivas

and Jesús Moreno Sierra

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2389 | Submission Open

Keywords: bladder cancer; kidney cancer; personalized medicine; prostate cancer; robotic surgery; targeted therapy; testicular cancer

(This special issue belongs to the Section Urology & Nephrology)

Early Diagnosis and Management of Glioma

edited by Maurizio Iacoangeli and

Denis Aiudi

submission deadline 31 Dec 2025 | 3 articles | Viewed by 2284 | Submission Open

Keywords: glioma; glioblastoma; neuroimaging; neuro-oncology; early diagnosis; modern technologies; neurosurgery; tumor biology; early therapy; new therapies

(This special issue belongs to the Section Oncology)

Prophylaxis, Diagnosis, and Treatment Strategies of Gastric Cancer

edited by Nadim Al Hajjar and Andra Ciocan

submission deadline 31 Dec 2025 | Viewed by 717 | Submission Open

Keywords: gastric cancer; treatment; prevention; diagnosis; surveillance; follow-up; neoadjuvant therapy; prognosis; biomarkers

(This special issue belongs to the Section Oncology)

Orthopedic Trauma: Surgical Treatment and Rehabilitation

edited by Yong Girl Rhee and Myung-seo Kim

submission deadline 31 Dec 2025 | 1 articles | Viewed by 602 | Submission Open

Keywords: orthopedic trauma; shoulder and elbow; knee; foot; and ankle; spine; fracture and dislocation; rotator cuff tear; surgery; rehabilitation

(This special issue belongs to the Section Orthopedics)

Hernia Repair: Current Advances and Challenges

edited by Fabrizio D'Acapito and Daniela Di Pietrantonio

submission deadline 31 Dec 2025 | 1 articles | Viewed by 597 | Submission Open

Keywords: hernia mesh repair; TAPP; IPOM; TARUP; component separation; artificial intelligence; robotic surgery; laparoscopy; mesh infection

(This special issue belongs to the Section Surgery)

Valve Diseases: Diagnosis and Treatment Innovations

edited by Vincenzo Caruso and Rajdeep Bilkhu

submission deadline 31 Dec 2025 | Viewed by 438 | Submission Open

Keywords: minimally invasive surgery; trans-catheter valve intervention; hybrid cardiac surgery; heart team; valve repair; Ross procedure; infective endocarditis

(This special issue belongs to the Section Cardiology)

Psoriasis and Related Conditions: Recent Advances and Controversies

edited by

Alin Laurentiu Tatu

and

Elena Niculeţ

submission deadline 31 Dec 2025 | Viewed by 150 | Submission Open

Keywords: psoriasis; cytopathology; skin disorder; immunology; patient care

(This special issue belongs to the Section Dermatology)

Melanoma: Updates and Path Forward

edited by

Davide Melandri

and

Fortunato Cassalia

submission deadline 31 Dec 2025 | Viewed by 148 | Submission Open

Keywords: melanoma; epidemiology of skin cancer; social media and skin cancer prevention; early diagnosis; artificial intelligence in dermatology; genetic and epigenetic factors; melanoma oncogenesis; tumour microenvironment; dermatopathology; biomarkers; melanoma-mimicking tumours; immunotherapy; targeted therapy; personalised medicine

(This special issue belongs to the Section Dermatology)

Advanced Research in Clinical Pharmacology and Epidemiology

edited by Dnyandev Gadhave

submission deadline 31 Dec 2025 | Viewed by 94 | Submission Open

Keywords: clinical pharmacology; epidemiology; pharmacokinetics; pharmacodynamics; drug delivery

(This special issue belongs to the Section Epidemiology & Public Health)

Updates on Oral Surgery

edited by

Mario Caggiano

and

Alfonso Acerra

submission deadline 31 Dec 2025 | Viewed by 85 | Submission Open

Keywords: oral surgery; digital technology; minimally invasive techniques; biomaterials; regenerative medicine; 3D printing; artificial intelligence; surgical navigation; robotics

(This special issue belongs to the Section Dentistry and Oral Health)

Tissue-Guided Repair

edited by

Tiberiu Paul Neagu

and

Ileana Peride

submission deadline 31 Dec 2025 | Viewed by 79 | Submission Open

Keywords: tissue injury; tissue repair; chronic wound; wound healing; wound dressing; skin homeostasis; wound microenvironment; wound contraction; scar; skin substitutes; guided regeneration

(This special issue belongs to the Section Dermatology)

Updates on Caries Management in the Primary and Permanent Dentition: 2nd Edition

edited by

Julian Schmoeckel

submission deadline 31 Dec 2025 | Viewed by 74 | Submission Open

Keywords: dental caries; treatment; caries management; children; adults; prevention; minimal-invasive

(This special issue belongs to the Section Dentistry and Oral Health)

Aortic Valve Replacement Innovations and Outcomes

edited by Basel Ramlawi and

Massimo Baudo

submission deadline 31 Dec 2025 | Viewed by 72 | Submission Open

Keywords: aortic valve replacement; cardiac surgery; minimally invasive; transcatheter; innovation; clinical outcomes; aortic stenosis; aortic regurgitation; technology

(This special issue belongs to the Section Cardiology)

Advances in GLP-1 Agonists and Liver Disease

edited by

Emidio Scarpellini

submission deadline 31 Dec 2025 | Viewed by 46 | Submission Open

Keywords: GLP-1 agonist; liver disease; liver steatosis; obesity; liver fibrosis

(This special issue belongs to the Section Gastroenterology & Hepatology)

Advancements in Dental Medicine, Oral Anesthesiology and Surgery

edited by Cosmin Sinescu,

Ciprian Roi

and

Mircea Riviș

submission deadline 10 Jan 2026 | 7 articles | Viewed by 9032 | Submission Open

Keywords: oral surgery; oral anesthesiology; implantology and guided surgery; oral tissue regeneration; periodontal disease; dental materials; oral medical devices; oral diseases

(This special issue belongs to the Section Dentistry and Oral Health)

Advances in Diagnosis and Therapies of Ocular Diseases

edited by

Ana Maria Dascalu

submission deadline 10 Jan 2026 | 3 articles | Viewed by 3254 | Submission Open

Keywords: early biomarkers; retinal and optic nerve imaging; ocular surgery; glaucoma drainage devices; neuroprotection; refraction errors; artificial intelligence

(This special issue belongs to the Section Ophthalmology)

Diabetes, Hypertension, and Cardiovascular Diseases: New Insights, Risk Factors, and Drug Therapies

edited by

Christina Chrysohoou

Panagiotis Theofilis

and

Emmanouil Mantzouranis

submission deadline 10 Jan 2026 | Viewed by 204 | Submission Open

Keywords: diabetes; hypertension; cardiovascular disease; cardiovascular risk factors; novel drug therapies; novel therapies; coronary artery disease; heart failure; precision medicine; artificial intelligence

(This special issue belongs to the Section Cardiology)

New Insights into Hypertension and the Cardiovascular System: 2nd Edition

edited by

Gwo-Ping Jong

submission deadline 15 Jan 2026 | Viewed by 89 | Submission Open

Keywords: hypertension; risk factors; oxidative stress; chronic inflammation; cardiovascular diseases

(This special issue belongs to the Section Cardiology)

Nutritional Management of Adults with Obesity

edited by

Alessandro Laviano

and

Salvatore Vaccaro

submission deadline 20 Jan 2026 | Viewed by 492 | Submission Open

Keywords: obesity; metabolic phenotype of obesity; nutritional management; nutritional intervention; nutritional educational program; precision nutrition; food compounds; dietary patterns; medical nutrition therapy (MNT); lifestyle intervention; physical activity program; traditional and innovative diets; therapeutic innovations

(This special issue belongs to the Section Endocrinology)

Craniomaxillofacial Surgery 4.0: Personalized Digital Planning, Augmented Reality, Point-of-Care Manufacturing and Molecular Data Integration

edited by

Maria J. Troulis

and

Manuel Tousidonis

submission deadline 20 Jan 2026 | Viewed by 77 | Submission Open

Keywords: craniomaxillofacial surgery; 3D printing; point-of-care manufacturing; microsurgery; reconstructive surgery; head and neck oncolog; rare jaw tumors; CCOC; minimally invasive surgery; tissue engineering; personalized digital planning; augmented reality; molecular data integration

(This special issue belongs to the Section Dentistry and Oral Health)

Recent Advances in Lower Urinary Tract Symptoms and Benign Prostatic Hyperplasia

edited by

Apostolos Apostolidis

and Efstathios Papaefstathiou

submission deadline 20 Jan 2026 | Viewed by 56 | Submission Open

Keywords: LUTS; BPH; minimally invasive treatment; digital health tools; biomarkers; microbiome

(This special issue belongs to the Section Urology & Nephrology)

Minimally Invasive Procedures in Cardiac Care

edited by

Antonello D’Andrea

Vincenzo Russo

and

Alfredo Mauriello

submission deadline 24 Jan 2026 | 2 articles | Viewed by 2866 | Submission Open

Keywords: minimally invasive cardiac care; valve surgery; coronary artery bypass grafting; heart failure management; surgical techniques; implantable cardioverter defibrillator; pacemaker; stellate ganglion blockage; aortic valve; mitral valve; hybrid approaches

(This special issue belongs to the Section Cardiology)

Recent Advances and Future Challenges in Orthopaedic Trauma Surgery

edited by Zinon Kokkalis and

Dimitrios Ntourantonis

submission deadline 25 Jan 2026 | Viewed by 134 | Submission Open

Keywords: orthopaedic trauma; fracture fixation; polytrauma; non-union; geriatric fractures; implant design; surgical innovation; perioperative care; postoperative rehabilitation

(This special issue belongs to the Section Orthopedics)

Advancements and Outcomes in Transcatheter Aortic Valve Implantation (TAVI)

edited by Dimitrios Iliopoulos and

Nikolaos Schizas

submission deadline 25 Jan 2026 | Viewed by 89 | Submission Open

Keywords: TAVI; transcatheter aortic valve implantation; TAVR; aortic valve replacement; aortic valve stenosis

(This special issue belongs to the Section Cardiology)

Exercise Rehabilitation Strategies for Long-Term Conditions in the Post-Pandemic Era

edited by

David Varillas-Delgado

and Sofía Laguarta-Val

submission deadline 26 Jan 2026 | Viewed by 63 | Submission Open

Keywords: therapeutic exercise; long covid; post-COVID syndrome; sports medicine; rehabilitation medicine; physiotherapy

(This special issue belongs to the Section Epidemiology & Public Health)

Minimally Invasive Strategies and New Techniques in Cardiovascular Surgery

edited by

Alexander Weymann

, Horatiu Suciu and

Marius Mihai Harpa

submission deadline 30 Jan 2026 | Viewed by 173 | Submission Open

Keywords: minimally invasive; endoscopic surgery; mitral repair; mini-thoracotomy; hybrid approach; percutaneous therapy

(This special issue belongs to the Section Cardiology)

The Association Between Cardiovascular Disease and Lung Cancer

edited by

Francesk Mulita

and

Vasileios Leivaditis

submission deadline 30 Jan 2026 | Viewed by 68 | Submission Open

Keywords: cardiovascular disease; lung cancer; incidence; mortality; survival; radiotherapy; chemotherapy

(This special issue belongs to the Section Cardiology)

Medicine and Dentistry: New Methods and Clinical Approaches—2nd Edition

edited by

Stefano Rizza

and Rocco Franco

submission deadline 31 Jan 2026 | 15 articles | Viewed by 24682 | Submission Open

Keywords: oral health; new materials; medical approach; periodontal disease; bruxism; oral surgery

(This special issue belongs to the Section Dentistry and Oral Health)

Current and Future Trends in Dentistry and Oral Health

edited by

Eva Klarić

Bruno Špiljak

and

Luka Šimunović

submission deadline 31 Jan 2026 | 5 articles | Viewed by 5643 | Submission Open

Keywords: digital dentistry; artificial intelligence in dentistry; biomaterials; orthodontics; endodontics; periodontics; oral– systemic health; dental public health; esthetic dentistry; implantology

(This special issue belongs to the Section Dentistry and Oral Health)

Clinical Recent Research in Rehabilitation and Preventive Medicine

edited by Mihai Berteanu,

Marius Nicolae Popescu

and

Mădălina-Gabriela Iliescu

submission deadline 31 Jan 2026 | 3 articles | Viewed by 4153 | Submission Open

Keywords: physical medicine; rehabilitation; injury prevention; wearable sensor devices (WSDs); biomechanics; regenerative medicine; musculoskeletal ultrasound (MSKUS); AI in medicine; telehealth; motion analysis

(This special issue belongs to the Section Sports Medicine and Sports Traumatology)

Novel Innovations in Diabetes Mellitus Prevention, Screening and Management

edited by

Anca Pantea Stoian

Teodor Salmen

and

Mihaela Adela Iancu

submission deadline 31 Jan 2026 | 3 articles | Viewed by 3320 | Submission Open

Keywords: diabetes mellitus; prevention; screening; complications; cardiovascular disease; neuropathy; retinopathy; nephropathy

(This special issue belongs to the Section Endocrinology)

Anterior Cruciate Ligament (ACL) Injury

edited by

Riccardo D'Ambrosi

and Alessandro Carrozzo

submission deadline 31 Jan 2026 | 3 articles | Viewed by 3077 | Submission Open

Keywords: anterior cruciate ligament; anterolateral ligament; arthroscopy; knee; sports medicine

(This special issue belongs to the Section Orthopedics)

Advances in Gynecological Cancer Research: Emerging Technologies and Future Therapeutic Strategies

edited by Jae-Yun Song and

Seongmin Kim

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2046 | Submission Open

Keywords: gynecological cancer; innovative surgical techniques; genomic profiling; personalized medicine; artificial intelligence (AI) in oncology; machine learning in diagnosis; cancer research technologies; future therapeutic strategies

(This special issue belongs to the Section Obstetrics and Gynecology)

Cardiovascular Disease: From Clinical Diagnosis to Management and Treatment

edited by Florin Mitu,

Maria-Magdalena Leon

and

Alexandra Maștaleru

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1717 | Submission Open

Keywords: cardiovascular disease; cardiac rehabilitation; secondary prevention; innovative treatment; risk stratification

(This special issue belongs to the Section Cardiology)

Recent Advances in Anesthesiology and Pain Medicine

edited by Adam Rudnik and

Izabela Duda

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1709 | Submission Open

Keywords: anesthetic procedures; perioperative monitoring; airway management; pain management; standards of anesthesia; perioperative care

(This special issue belongs to the Section Intensive Care/ Anesthesiology)

Clinical Treatment of Neuroendocrine Neoplasm

edited by Michele Klain and

Leandra Piscopo

submission deadline 31 Jan 2026 | 1 articles | Viewed by 814 | Submission Open

Keywords: neuroendocrine neoplasms; neuroendocrine cell system; gastro-entero-pancreatic NENs; immunohistochemical analysis; Ki-67 index; mitotic count; somatostatin analogue therapy; antiproliferative effect; positron emission tomography/computed tomography (PET/CT); peptide receptor radionuclide therapy (PRRT)

(This special issue belongs to the Section Oncology)

Clinical Advances in Cardiopulmonary Bypass Surgery: Innovations and Impacts on Patient Outcomes

edited by

Irina-Iuliana Costache

Ștefania-Teodora Duca

and Lucian Stoica

submission deadline 31 Jan 2026 | 1 articles | Viewed by 569 | Submission Open

Keywords: cardiac surgery; cardiopulmonary bypass; patient outcome; surgical techniques; extracorporeal circulation; postoperative care; perfusion strategies

(This special issue belongs to the Section Cardiology)

Advances in Gastrointestinal Surgeries

edited by Matei Bratu, Bogdan Diaconescu and Florin Iordache

submission deadline 31 Jan 2026 | 1 articles | Viewed by 385 | Submission Open

Keywords: minimal invasive surgery; oncologic surgery; endoscopic surgery; rare cases

(This special issue belongs to the Section Surgery)

Coronary CT Angiography in Coronary Artery Disease: Challenges and Future Opportunities

edited by

Nikolaos Ktenopoulos

and Andreas Synetos

submission deadline 31 Jan 2026 | Viewed by 132 | Submission Open

Keywords: coronary CT angiography; coronary artery disease; cardiac imaging; non-invasive imaging; INOCA/ANOCA

(This special issue belongs to the Section Cardiology)

Clinical Ophthalmology: Current Status and Future Challenges

edited by

Theodora Papamitsou

, Athanasios Karamitsos and

Sofia Karachrysafi

submission deadline 31 Jan 2026 | Viewed by 122 | Submission Open

Keywords: clinical ophthalmology; ophthalmic pharmacology; biomarkers in eye diseases; ocular diagnostics; AI in ophthalmology; minimally invasive eye surgery; retinal diseases; gene therapy in ophthalmology; surgical innovations in ophthalmology; regenerative medicine for eye diseases

(This special issue belongs to the Section Ophthalmology)

Research Progress in Oral and Periodontal Surgery

edited by

Pradeep Koppolu

submission deadline 31 Jan 2026 | Viewed by 110 | Submission Open

Keywords: implants; biomarkers; mucogingival procedures; regeneration; lasers

(This special issue belongs to the Section Dentistry and Oral Health)

Displaying special issue 151-200 on page 4 of 7.

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