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Medicina
Special Issues
Advances and Challenges in Skeletal Diseases
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Advances and Challenges in Skeletal Diseases

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Orthopedics".

Deadline for manuscript submissions: 15 December 2026 | Viewed by 1261

Special Issue Editors

Prof. Dr. Sebastian Głowiński

E-Mail Website
Guest Editor
1. Institute of Health Sciences, Pomeranian University in Slupsk, Westerplatte 64, 76-200 Slupsk, Poland
2. Institute of Physical Culture and Health, State Academic of Applied Sciences in Koszalin, Leśna 1, 75-582 Koszalin, Poland
Interests: exoskeletons; spine problems
Special Issues, Collections and Topics in MDPI journals
Dr. Aleksandra Bryndal

E-Mail Website
Guest Editor Assistant
1. Institute of Health Sciences, Pomeranian University in Slupsk, Westerplatte 64, 76-200 Slupsk, Poland
2. Institute of Physical Culture and Health, State Academic of Applied Sciences in Koszalin, Leśna 1, 75-582 Koszalin, Poland
Interests: spinal pain disorders; occupational physiotherapy; physiotherapy in pregnancy; clinical neurophysiology

Special Issue Information

Dear Colleagues,

Musculoskeletal diseases affect millions of people worldwide, with their prevalence increasing due to aging populations and sedentary lifestyles. Conditions such as osteoporosis, degenerative joint disease, and occupational diseases significantly impact quality of life and healthcare systems.

Rehabilitation and physiotherapy have become among the fundamental interventions in the treatment of musculoskeletal diseases. Modern approaches combine evidence-based protocols with innovative technologies, such as virtual reality-assisted rehabilitation, robotic therapy, and wearable monitoring devices. These advances offer new opportunities to optimize treatment outcomes and develop personalized interventions.

This Special Issue focuses on the latest achievements in the treatment of musculoskeletal diseases, with particular emphasis on rehabilitation and physiotherapy interventions. Our goal is to bridge basic research with clinical application, supporting collaboration between researchers and healthcare professionals in the field of musculoskeletal health.

In this Special Issue, we invite submissions on the following topics:

  • Innovative rehabilitation protocols;
  • Exercise therapy optimization and biomechanical analysis in musculoskeletal disease treatment;
  • Technology-enhanced rehabilitation, including virtual reality, robotics, and health monitoring devices;
  • Manual therapy techniques;
  • Pain management strategies in chronic musculoskeletal conditions;
  • Preventive physiotherapy approaches for maintaining musculoskeletal health;
  • Telerehabilitation and digital solutions in musculoskeletal disease treatment;
  • Interdisciplinary approaches combining physiotherapy with other therapeutic methods.

We welcome original research articles, systematic reviews, meta-analyses, and clinical trials that advance our knowledge and improve clinical practice in the rehabilitation and physiotherapy of musculoskeletal diseases.

Prof. Dr. Sebastian Głowiński
Guest Editor

Dr. Aleksandra Bryndal
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • musculoskeletal diseases
  • rehabilitation
  • physiotherapy
  • manual therapy
  • exercise therapy
  • virtual reality rehabilitation
  • robotic therapy
  • pain management
  • telerehabilitation

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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15 pages, 837 KB  
Article
Postoperative Outcomes of Transaxillary First Rib Resection with Anterior Scalenotomy for Thoracic Outlet Syndrome: An Ambispective Multimodal Cohort Study
by Thrasyvoulos Michos, Anastasia Roumpaki, Emmanouil I. Kapetanakis, Petros Michos, Ioannis Gakidis, Christos Chantziantoniou, Aikaterini Kotroni, Ioanna Vlachou, Asterios Kanakis, Vicenzo Castilletti, Chara Tzavara, George Babis, Periklis Tomos and Spiros Pneumaticos
Medicina 2026, 62(4), 735; https://doi.org/10.3390/medicina62040735 - 12 Apr 2026
Viewed by 407
Abstract
Background and Objectives: This study aimed to evaluate postoperative outcomes following transaxillary first rib resection with concomitant anterior scalenotomy (Roos procedure) for Thoracic Outlet Syndrome, using an ambispective design with a standardized two-year multimodal follow-up in a prospectively observed subgroup. Materials and [...] Read more.
Background and Objectives: This study aimed to evaluate postoperative outcomes following transaxillary first rib resection with concomitant anterior scalenotomy (Roos procedure) for Thoracic Outlet Syndrome, using an ambispective design with a standardized two-year multimodal follow-up in a prospectively observed subgroup. Materials and Methods: This ambispective observational cohort study included 32 patients (87.5% women; mean age, 33.8 years) who underwent transaxillary first rib resection with anterior scalenotomy for Thoracic Outlet Syndrome. Of these, seven patients comprised the retrospective cohort, having undergone surgery between 2017 and 2019, while the remaining 25 patients were enrolled prospectively and underwent surgery from 2020 onwards. Patients were classified as having neurogenic, vascular (arterial or venous), or mixed Thoracic Outlet Syndrome. Retrospective data were obtained from medical records, while prospectively treated patients were followed according to a predefined postoperative protocol. Longitudinal changes in clinical outcomes were analyzed using mixed linear and logistic regression models. Results: All analyzed symptoms improved after surgery (p < 0.05), with a significant reduction in upper limb edema over time (OR = 0.44, p = 0.002). The prevalence of positive provocative tests decreased notably across all maneuvers postoperatively. Pathological color duplex ultrasound findings of the upper limb vessels resolved almost completely during follow-up. Patient-reported outcome measures (CBSQ, DASH, and BPI) demonstrated meaningful postoperative improvement with sustained benefits over time. Electrophysiological evaluation revealed notable improvement in median sensory and motor nerve conduction parameters. Conclusions: Transaxillary first rib resection with anterior scalenotomy appears to improve clinical, functional, and objective outcomes in patients with Thoracic Outlet Syndrome; however, findings should be interpreted with caution due to the ambispective design, small sample size, and cohort heterogeneity, and require confirmation in larger prospective studies. Full article
(This article belongs to the Special Issue Advances and Challenges in Skeletal Diseases)
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14 pages, 798 KB  
Article
Intraoperative Electromyographic Evaluation of Brachial Plexus Decompression During the Roos Surgical Procedure for Thoracic Outlet Syndrome
by Thrasyvoulos Michos, Anastasia Roumpaki, Emmanouil I. Kapetanakis, Petros Michos, Ioannis Gakidis, Christos Chantziantoniou, Aikaterini Kotroni, Ioanna Vlachou, Asterios Kanakis, Vicenzo Castilletti, Dimitris Lazos, Chara Tzavara, George Babis, Periklis I. Tomos and Spiros Pneumaticos
Medicina 2026, 62(2), 332; https://doi.org/10.3390/medicina62020332 - 6 Feb 2026
Viewed by 474
Abstract
Background and Objectives: The aim of this retrospective study was to assess brachial plexus decompression throughout the sequential stages of the Roos procedure and to elucidate the role of first rib resection in the surgical management of Thoracic Outlet Syndrome (T.O.S). Materials and [...] Read more.
Background and Objectives: The aim of this retrospective study was to assess brachial plexus decompression throughout the sequential stages of the Roos procedure and to elucidate the role of first rib resection in the surgical management of Thoracic Outlet Syndrome (T.O.S). Materials and Methods: A total of 34 patients with a mean age of 34.6 years were included in this retrospective analysis. All patients underwent transaxillary first rib resection following anterior scalenotomy, consistent with the Roos procedure. Intraoperative brachial plexus functionality was assessed using recording electrodes for sensory and motor stimulation on the deltoid, biceps, triceps brachii, and abductor digiti minimi muscles. Mixed linear models with log-transformed data were used to assess changes in muscle measurements across surgical stages, with statistical significance at p less than 0.05. Results: The electromyographic values of the deltoid, biceps brachii, triceps brachii, and abductor digiti minimi muscles were significantly higher in the final post-operative neutral position compared to both the post-anterior scalenotomy and initial preoperative neutral positions. No significant differences were observed between the initial preoperative neutral position and the post-anterior scalenotomy values for these muscles. However, the abductor digiti minimi muscle exhibited a trend toward decreased values following anterior scalenotomy in comparison to the initial neutral position. Conclusions: Intraoperative outcomes of brachial plexus decompression during the Roos procedure demonstrate that first rib resection contributes to complete decompression of the relevant anatomical structures in Thoracic Outlet Syndrome. Full article
(This article belongs to the Special Issue Advances and Challenges in Skeletal Diseases)
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