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Medicina publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Insights and Advances in Cancer Biomarkers

edited by

Krishan Jain

submission deadline 30 Sep 2025 | 6 articles | Viewed by 6537 | Submission Open

Keywords: liquid biopsies; cancer biomarkers; cellular immunotherapy; single-cell sequencing; immune biomarkers; epigenetic markers; microbiome and metabolomics; proteomics; multiomics; machine learning; generative AI

(This special issue belongs to the Section Oncology)

New Insights into Neurodevelopmental Biology and Disorders

edited by

Rekha Jagadapillai

submission deadline 30 Sep 2025 | 2 articles | Viewed by 5875 | Submission Open

Keywords: neurodevelopment; neurodevelopmental biology; neurodevelopmental disorders; autism spectrum disorders (ASDs); down syndrome; ADHD; cerebral palsy; learning disability

(This special issue belongs to the Section Neurology)

AI in Imaging—New Perspectives, 2nd Edition

edited by

Ivo Dumić-Čule

submission deadline 30 Sep 2025 | 2 articles | Viewed by 3139 | Submission Open

Keywords: artificial intelligence; imaging; machine learning; radiology; ethics; big data

(This special issue belongs to the Section Surgery)

State-of-the-Art Therapeutics and Imaging in Knee Surgery

edited by

Cristian Scheau

Romica Cergan

and

Serban Dragosloveanu

submission deadline 30 Sep 2025 | 2 articles | Viewed by 3059 | Submission Open

Keywords: knee surgery; minimally invasive techniques; regenerative medicine; diagnostic imaging modalities; MRI in knee surgery; CT and ultrasound imaging; novel surgical approaches; pharmacological treatments; patient outcomes; precision surgery; state-of-the-art therapies; clinical advancements; surgical precision; efficacy of knee treatments; robotic knee surgery; surgery-related costs; 3D-printing in knee surgery; novel surgical biomaterials; anatomical landmarks; knee morphometry

(This special issue belongs to the Section Surgery)

Recent Breakthroughs in the Diagnosis and Treatment of Oral Inflammatory Diseases

edited by

Liborija Lugović-Mihić

and

Ana Glavina

submission deadline 30 Sep 2025 | 2 articles | Viewed by 2921 | Submission Open

Keywords: oral inflammatory diseases; multidisciplinary; clinical manifestation; diagnosis; treatment; clinical outcome

(This special issue belongs to the Section Dentistry and Oral Health)

Towards Improved Cancer Diagnosis: New Developments in Histopathology

edited by

Ovidiu Simion Cotoi

and

Iuliu Gabriel Cocuz

submission deadline 30 Sep 2025 | 4 articles | Viewed by 2605 | Submission Open

Keywords: histopathology; cancer diagnosis; digital pathology; molecular pathology; dermatopathology

(This special issue belongs to the Section Oncology)

Updates on Prevention of Acute Heart Failure

edited by

Cristina Tudoran

submission deadline 30 Sep 2025 | 2 articles | Viewed by 2093 | Submission Open

Keywords: acute heart failure; treatment of acute heart failure; management of acute heart failure; prevention of acute heart failure; chronic decompensated heart failure

(This special issue belongs to the Section Cardiology)

Hepato-Biliary-Pancreatic Surgery: Clinical Updates and Future Perspectives

edited by

Marco Massani

and

Tommaso Stecca

submission deadline 30 Sep 2025 | 3 articles | Viewed by 2031 | Submission Open

Keywords: HPB surgery; liver cancer; pancreatic cancer; biliary tract cancer

(This special issue belongs to the Section Surgery)

Advances in Corneal Management

edited by Sanja Masnec and Rafael I. Barraquer

submission deadline 30 Sep 2025 | 2 articles | Viewed by 1990 | Submission Open

Keywords: cornea; corneal disease; corneal transplantation; keratoconus; keratoplasty; penetrating keratoplasty; descemet stripping automated endothelial keratoplasty; deep anterior lamellar keratoplasty; descemet membrane endothelial keratoplasty; cross-linking; corneal infections; refractive surgery; photorefractive keratectomy; laser-assisted in situ keratomileusis; kerato– lenticule extraction; corneal imaging

(This special issue belongs to the Section Ophthalmology)

Surgical Approaches in Thyroid, Breast, and Other Endocrine Cancers: Advances and Challenges

edited by

Francesk Mulita

and Levan Tchabashvili

submission deadline 30 Sep 2025 | 2 articles | Viewed by 1397 | Submission Open

Keywords: endocrine surgery; breast cancer; thyroid diseases; surgical complications

(This special issue belongs to the Section Surgery)

Advances in Imaging and Diagnostics in Lung Disease: A Multimodal Approach

edited by Diana Manolescu and

Emil Robert Stoicescu

submission deadline 30 Sep 2025 | 2 articles | Viewed by 1066 | Submission Open

Keywords: lung imaging; multimodal diagnostics; MRI; HRCT; lung ultrasound; pulmonary biomarkers; hybrid imaging; interstitial lung disease; AI in imaging; pulmonary medicine

(This special issue belongs to the Section Pulmonology)

Magnetic Resonance in Various Diseases and Biomedical Applications

edited by

Francesco Tiralongo

and

Antonio Basile

submission deadline 30 Sep 2025 | 1 articles | Viewed by 969 | Submission Open

Keywords: magnetic resonance imaging; MRI; magnetic resonance imaging biomarkers; neuroimaging; cancer imaging; abdominal imaging; pelvic imaging; musculoskeletal imaging; cardiac imaging; medical imaging; diffusion imaging; tensor imaging; functional imaging; magnetic resonance angiography

(This special issue belongs to the Section Infectious Disease)

Emerging Therapies for Gastric Cancer

edited by

Rui Caetano Oliveira

and

José Guilherme Tralhão

submission deadline 30 Sep 2025 | Viewed by 438 | Submission Open

Keywords: gastric cancer; oncology; therapies; individualized therapy; immunotherapy

(This special issue belongs to the Section Gastroenterology & Hepatology)

Current Advances in Foot and Ankle Surgery

edited by Min Gyu Kyung and Dong-Oh Lee

submission deadline 30 Sep 2025 | Viewed by 330 | Submission Open

Keywords: orthopedics; foot and ankle; osteoarthritis; trauma; gait analysis; advances; diagnosis; treatment; prognosis

(This special issue belongs to the Section Orthopedics)

Clinical and Surgical Updates on Bariatric Surgery

edited by

Claudio Gambardella

submission deadline 30 Sep 2025 | Viewed by 265 | Submission Open

Keywords: bariatric surgery; morbid obesity; sleeve gastrectomy; gastric bypass; surgical complications; diabetes remission; hypertension remission; hypercholesterolemia remission; GERD; de novo GERD

Atrial Fibrillation and Heart Failure Management

edited by Erika Bertella

submission deadline 30 Sep 2025 | Viewed by 195 | Submission Open

Keywords: heart failure; cardiac magnetic resonance; cardiac computed tomography; echocardiography; atrial fibrillation; electrophysiology; surgery

(This special issue belongs to the Section Cardiology)

Advances in Structural Heart Diseases

edited by

Konstantinos Papadopoulos

Ignatios Ikonomidis

and Erwan Donal

submission deadline 30 Sep 2025 | Viewed by 179 | Submission Open

Keywords: valvular heart diseases; transcatheter interventions; TEER; LAA closure; ASD closure; interventional echocardiography; multimodality cardiac imaging; three-dimensional echocardiography

(This special issue belongs to the Section Cardiology)

Advances in the Prevention, Diagnosis and Management of Surgical Complications After Kidney Transplantation

edited by

Vassilios Papalois

and

Nikolaos-Andreas Anastasopoulos

submission deadline 30 Sep 2025 | Viewed by 140 | Submission Open

Keywords: kidney transplantation; bleeding; surgical site infection; post operative pain; incisional hernia; vascular complications; ureteric complications; prevention; surgical technology

(This special issue belongs to the Section Urology & Nephrology)

Recent Advances in Digestive Endoscopy

edited by

Marco Spadaccini

and

Alessandro Fugazza

submission deadline 30 Sep 2025 | Viewed by 115 | Submission Open

Keywords: digestive endoscopy; cholangiopancreatography; advanced endoscopy

(This special issue belongs to the Section Gastroenterology & Hepatology)

Prostate Cancer in the Molecular Era

edited by

Jan Lubinski

and

Milena Matuszczak

submission deadline 30 Sep 2025 | Viewed by 112 | Submission Open

Keywords: prostate cancer; precision medicine; molecular target; molecular oncology; tumor microenvironment; prognostic biomarker; predictive biomarker; liquid biopsy; precision medicine

(This special issue belongs to the Section Oncology)

Coronary Artery Disease from Acute Manifestation to Long Term Consequences

edited by

Elena Emilia Babeş

submission deadline 1 Oct 2025 | 1 articles | Viewed by 913 | Submission Open

Keywords: coronary artery disease; acute coronary syndrome; coronary revascularization; coronary angiography; CT angiography; antiplatelet therapy; inflammation

(This special issue belongs to the Section Cardiology)

Peripheral Artery Disease in Thromboinflammation Era: Pathophysiological, Clinical and Therapeutic Implications

edited by

Giuseppe Miceli

and

Antonino Tuttolomondo

submission deadline 1 Oct 2025 | Viewed by 116 | Submission Open

Keywords: thromboinflammation; peripheral artery disease; atherosclerosis; acute limb ischemia

(This special issue belongs to the Section Cardiology)

Modern Diagnostics and Therapy for Vitreoretinal Diseases

edited by

Miguel Antonio Busquets

and

Anat Lowenstein

submission deadline 10 Oct 2025 | 1 articles | Viewed by 1662 | Submission Open

Keywords: retinal pharmacotherapy; artificial intelligence; image recognition; optical coherence tomography; remote retinal monitoring; exudative retinal disease; geographic atrophy

(This special issue belongs to the Section Ophthalmology)

Clinical Updates and Future Perspectives on the Chronic Pain Management

edited by

Sergio Hernández Sánchez

and

Jasemin Todri

submission deadline 15 Oct 2025 | 1 articles | Viewed by 814 | Submission Open

Keywords: chronic pain management; pain assessment; regenerative medicine in pain management; multidisciplinary pain treatment; wearable technology in pain monitoring; personalized pain therapy

(This special issue belongs to the Section Neurology)

Revolutionizing Cardiopulmonary Resuscitation: Contemporary Advances and Challenges

edited by Georgios Mavrovounis,

Ioannis Pantazopoulos

and

Maria Mermiri

submission deadline 20 Oct 2025 | 2 articles | Viewed by 3714 | Submission Open

Keywords: cardiopulmonary resuscitation; defibrillation; mechanical CPR; emergency medicine; automated external defibrillator; e-CPR; post-resuscitation period; neurological outcomes

(This special issue belongs to the Section Intensive Care/ Anesthesiology)

Gut Microbiota and Gastrointestinal Cancer: Pathways to Progression and Opportunities for Intervention

edited by Vikas Kumar Somani,

Naoshad Muhammad

and

Somya Aggarwal

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1754 | Submission Open

Keywords: gut microbiota; gastrointestinal cancer; dysbiosis; colorectal cancer; gastric cancer; pancreatic cancer; esophageal cancer; cancer progression; tumor microenvironment; inflammation; immune modulation; metabolic alterations; probiotics; prebiotics; microbial therapies; fecal microbiota transplantation; cancer immunotherapy; tumor-associated microbiome; gut– brain axis; microbiome modulation

(This special issue belongs to the Section Oncology)

Pulmonary Fibrosis: Current Understanding and Future Directions

edited by Satoshi Okamori and

Yusuke Nakamura

submission deadline 25 Oct 2025 | 1 articles | Viewed by 458 | Submission Open

Keywords: pulmonary fibrosis; interstitial lung disease (ILD); idiopathic pulmonary fibrosis (IPF); hypersensitivity pneumonitis; bronchoscopy; cryobiopsy; fibrotic lung disease; acute exacerbations; pleuroparenchymal fibroelastosis; rehabilitation; nutrition

(This special issue belongs to the Section Pulmonology)

Epidemiology of Geriatric Syndromes: Life Course Risk or Protective Factors

edited by Carlos Alfonso Reyes-Ortiz

submission deadline 25 Oct 2025 | Viewed by 440 | Submission Open

Keywords: older adults; geriatric syndromes; chronic disease; early life adversity; adverse childhood experiences; risk factors; protective factors

Development and Application of Digestive Endoscopy

edited by

Giacomo Emanuele Maria Rizzo

, Sara Nikolic and

Lucía Guilabert

submission deadline 25 Oct 2025 | Viewed by 133 | Submission Open

Keywords: endoscopy; endoscopic ultrasound; interventional endoscopy; robotic endoscopy; gastroenterology; advanced imaging

(This special issue belongs to the Section Gastroenterology & Hepatology)

Advances in Pathogenesis, Rehabilitation, and Treatment of Knee Osteoarthritis

edited by

László Irsay

and Magdalena-Rodica Trăistaru

submission deadline 25 Oct 2025 | Viewed by 113 | Submission Open

Keywords: pathogenesis; evidence based KOA; rehabilitation KOA; treatment KOA; surgery KOA

(This special issue belongs to the Section Orthopedics)

Multimodal Imaging Techniques in Myocardial Ischemia: Current Applications and Future Prospects

edited by Fausto Pizzino and Giovanni Concistrè

submission deadline 30 Oct 2025 | 3 articles | Viewed by 4948 | Submission Open

Keywords: myocardial ischemia; cardiac magnetic resonance; coronary computed tomography angiography; intravascular imaging; myocardial infarction with non-obstructive coronary arteries; ischemia with non-obstructive coronary arteries; coronary artery disease

(This special issue belongs to the Section Cardiology)

Advances and Perspectives in Esophageal Cancer Treatment

edited by Koji Otsuka and

Florin Achim

submission deadline 30 Oct 2025 | Viewed by 2297 | Submission Open

Keywords: minimally invasive esophagectomy; robotic esophagectomy; locally advanced esophageal cancer; immunotherapy for esophageal cancer; cervical esophageal cancer; multidisciplinary approach to esophageal cancer

(This special issue belongs to the Section Surgery)

The Challenges and Prospects in Clinical Cardiology and Angiology

edited by Vincenzo Zaccone and

Giulio Francesco Romiti

submission deadline 31 Oct 2025 | 6 articles | Viewed by 15317 | Submission Open

Keywords: cardiology; angiology; cardiovascular diseases; vascular health; diagnostic techniques; treatment strategies; translational research

(This special issue belongs to the Section Cardiology)

Current Advancements in Menopause Treatment and Management

edited by Richa Sood

submission deadline 31 Oct 2025 | 3 articles | Viewed by 9967 | Submission Open

Keywords: menopause; vasomotor symptoms; hormone therapy; tele-medicine; drug innovation; machine learning; artificial intelligence; cardiovascular; osteoporosis

(This special issue belongs to the Section Obstetrics and Gynecology)

Innovations in Amputation Care

edited by

Gerhard M. Hobusch

and

Jennifer Ernst

submission deadline 31 Oct 2025 | 4 articles | Viewed by 8787 | Submission Open

Keywords: bone-anchored prosthesis; targeted muscle reinnervation; amputation medicine; targeted sensory reinnervation; artificial intelligence; motor imagery; digital transformation; patient-reported outcome measurement

(This special issue belongs to the Section Orthopedics)

Future Trends in Breast Cancer Management

edited by

Dinesh K. Thekkinkattil

submission deadline 31 Oct 2025 | 5 articles | Viewed by 8616 | Submission Open

Keywords: breast cancer; breast reconstruction; artificial intelligence; machine learning; staging; treatment; targeted therapy; digital pathology; radiomics; oncoplastic surgery; prognosis; immunotherapy; liquid biopsy

(This special issue belongs to the Section Oncology)

Advanced Technologies in Pediatric Nephrology

edited by Kiran K. Upadhyay

submission deadline 31 Oct 2025 | 3 articles | Viewed by 5156 | Submission Open

Keywords: pediatrics; kidney transplantation; dialysis; hypertension; nephrotic syndrome; glomerulonephritis; lupus nephritis; chronic kidney disease; voiding dysfunction; renal tubular disease

(This special issue belongs to the Section Pediatrics)

Addressing the Changes and Innovations in the Treatment of Gynecological Cancers

edited by

Federico Ferrari

submission deadline 31 Oct 2025 | 3 articles | Viewed by 4563 | Submission Open

Keywords: ovarian cancer; endometrial cancer; cervical cancer; minimally invasive surgery; adjuvant treatment; targeted therapy; immunotherapy; endoscopy

(This special issue belongs to the Section Oncology)

Gastric Sleeve Surgery: Techniques, Outcomes, and Future Directions

edited by Anna Maria Różańska-Walędziak and

Maciej Walędziak

submission deadline 31 Oct 2025 | 3 articles | Viewed by 4534 | Submission Open

Keywords: laparoscopic sleeve gastrectomy; bariatric surgery; obesity

(This special issue belongs to the Section Surgery)

Diagnosis and Treatment of Valvular Heart Diseases

edited by

Valentina Grazioli

and Ilaria Franzese

submission deadline 31 Oct 2025 | 3 articles | Viewed by 3392 | Submission Open

Keywords: valvular heart disease; aortic valve disease; mitral valve disease; tricuspid valve disease; pulmonary valve disease; transcatheter intervention; surgery

(This special issue belongs to the Section Cardiology)

Current Management and Future Challenges of Severe Traumatic Brain Injury

edited by Nasim Ahmed

submission deadline 31 Oct 2025 | 1 articles | Viewed by 2293 | Submission Open

Keywords: severe traumatic brain injury; computed tomography; magnetic resonance imaging; decompressive craniectomy; neurosurgical; trauma surgery; Surgical critical care; acute care surgery

(This special issue belongs to the Section Intensive Care/ Anesthesiology)

Transcatheter Therapies for Valvular Heart Disease

edited by

Massimo Baudo

and Basel Ramlawi

submission deadline 31 Oct 2025 | 3 articles | Viewed by 2199 | Submission Open

Keywords: aortic valve transcatheter interventions; mitral valve transcatheter interventions; tricuspid valve transcatheter interventions; pulmonary valve transcatheter interventions; transcatheter aortic valve intervention/replacement; mitral transcatheter edge-to-edge repair; transcatheter mitral valve replacement; percutaneous annuloplasty; tricuspid transcatheter edge-to-edge repair; transcatheter pulmonary valve replacement

(This special issue belongs to the Section Cardiology)

Progress in Venous Thromboembolism Research

edited by Mihaela Hostiuc

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1134 | Submission Open

Keywords: venous thromboembolism; cardiovascular disease; post-thrombotic syndrome; chronic thromboembolic pulmonary disease; prevention

Techniques, Risks and Recovery of Hip Surgery

edited by

Alberto D. Delgado-Martínez

Eduardo García-Rey

and Enrique Guerado

submission deadline 31 Oct 2025 | 1 articles | Viewed by 659 | Submission Open

Keywords: hip surgery; hip fracture; hip arthroplasty; hip arthroscopy

(This special issue belongs to the Section Orthopedics)

Advances and Challenges in Prehospital Emergency Care

edited by Hayley L. Letson

submission deadline 31 Oct 2025 | 1 articles | Viewed by 587 | Submission Open

Keywords: prehospital; trauma; injury; traumatic brain injury; burns; cardiac arrest; stroke; rural/remote; emergency; resuscitation

(This special issue belongs to the Section Intensive Care/ Anesthesiology)

Advances and Future Perspectives in Abdominal and Gastrointestinal Surgery

edited by Stamatis Angelopoulos, Efstathios Kotidis and

Elissavet Anestiadou

submission deadline 31 Oct 2025 | 1 articles | Viewed by 447 | Submission Open

Keywords: abdominal surgery; gastrointestinal surgery; general surgery; minimally invasive surgery; perioperative management; surgical innovation

(This special issue belongs to the Section Gastroenterology & Hepatology)

Advances in Head and Neck Cancer Management

edited by

Primož Strojan

and

Domen Vozel

submission deadline 31 Oct 2025 | 1 articles | Viewed by 395 | Submission Open

Keywords: head and neck cancer; targeted therapies; Immunotherapy; imaging techniques; skull-base cancer; radiation therapy

(This special issue belongs to the Section Oncology)

Impact of Endothelial Dysfunction on Cardiovascular and Pulmonary Diseases

edited by Yuri Matusov and Suhail Dohad

submission deadline 31 Oct 2025 | Viewed by 358 | Submission Open

Keywords: thromboembolic disease; pulmonary hypertension; peripheral arterial disease; coronary artery disease; pulmonary embolism; venous insufficiency

(This special issue belongs to the Section Cardiology)

Clinical Application of State-of-the-Art Robotic Surgery

edited by

Jin Wook Yi

submission deadline 31 Oct 2025 | 1 articles | Viewed by 351 | Submission Open

Keywords: surgery for thyroid; parathyroid; and adrenal glands; endoscopic and robotic surgery; basic research of thyroid; parathyroid; and adrenal glands

(This special issue belongs to the Section Surgery)

Clinical Updates and Future Perspectives on Acute Myocardial Infarction

edited by Ciro Mauro, Fulvio Cacciapuoti and Gerardo Carpinella

submission deadline 31 Oct 2025 | Viewed by 166 | Submission Open

Keywords: acute myocardial infarction; early-phase management; long-term cardiac care; mechanical circulatory support; intensive care; lipid-lowering and cardioprotective therapies; precision medicine and artificial intelligence in cardiology

(This special issue belongs to the Section Cardiology)

Displaying special issue 51-100 on page 2 of 7.

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