Cardiovascular Disease: From Clinical Diagnosis to Management and Treatment

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: 31 January 2026 | Viewed by 1349

Special Issue Editors


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Guest Editor
1. Department of Medical Specialties I, Faculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, Romania
2. Clinical Rehabilitation Hospital, 700661 Iasi, Romania
Interests: cardiology; internal medicine; cardiac rehabilitation; sports medicine

E-Mail Website
Guest Editor
1. Department of Medical Specialties I, Faculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, Romania
2. Clinical Rehabilitation Hospital, 700661 Iasi, Romania
Interests: cardiology; internal medicine; cardiac rehabilitation; sports medicine
Special Issues, Collections and Topics in MDPI journals

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Guest Editor Assistant
1. Department of Medical Specialties I, Faculty of Medicine, University of Medicine and Pharmacy “Grigore T. Popa”, 700115 Iasi, Romania
2. Clinical Rehabilitation Hospital, 700661 Iasi, Romania
Interests: cardiology; cardiovascular; cholesterol

Special Issue Information

Dear Colleagues,

Cardiovascular diseases (CVDs) are a leading cause of death worldwide. Their prevalence has increased due to an aging population, lifestyle changes, and rising diabetes and obesity rates. Despite medical advances, cardiovascular diseases continue to challenge healthcare systems worldwide, requiring ongoing research for new treatments, diagnostic tools, and prevention methods. This Special Issue combines cutting-edge clinical practice research with scientific discoveries. The goals are to develop innovative diagnosis, risk stratification, management, and treatment methods, as well as a better understanding of pathophysiological mechanisms. The Special Issue will collate cutting-edge research in personalized medicine in cardiovascular rehabilitation, artificial intelligence in heart disease prediction and management, and new drug therapies. We are particularly interested in cardiovascular rehabilitation, stem cell therapies for cardiac tissue repair, and the genetics of cardiovascular disorders. We are also interested in novel approaches to comorbidities such as diabetes and chronic kidney disease, which increase cardiovascular risk. We seek original research articles, systematic reviews, and clinical studies on the latest cardiovascular diagnostic tools, therapeutic approaches, and technologies. This Special Issue provides a comprehensive overview of the current clinical practices and future cardiovascular disease management and treatment trends to improve patient outcomes and reduce heart disease worldwide.

Yours faithfully,

Prof. Dr. Florin Mitu
Prof. Dr. Maria-Magdalena Leon
Guest Editors

Dr. Alexandra Maștaleru
Guest Editor Assistant

Manuscript Submission Information

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Keywords

  • cardiovascular disease
  • cardiac rehabilitation
  • secondary prevention
  • innovative treatment
  • risk stratification

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Published Papers (1 paper)

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Review

21 pages, 605 KiB  
Review
Cardiac Rehabilitation in TAVI Patients: Safety and Benefits: A Narrative Review
by Theodor Constantin Stamate, Cristina Andreea Adam, Radu Sebastian Gavril, Radu Ștefan Miftode, Andreea Rotundu, Ovidiu Mitu, Doina Clementina Cojocaru, Grigore Tinică and Florin Mitu
Medicina 2025, 61(4), 648; https://doi.org/10.3390/medicina61040648 - 1 Apr 2025
Viewed by 736
Abstract
Transcatheter aortic valve implantation (TAVI) has redefined the management of severe aortic stenosis, particularly in surgical high-risk patients. As the number of TAVI procedures increases, there is a growing need for effective post-procedural care. Cardiac rehabilitation (CR) has emerged as a critical component [...] Read more.
Transcatheter aortic valve implantation (TAVI) has redefined the management of severe aortic stenosis, particularly in surgical high-risk patients. As the number of TAVI procedures increases, there is a growing need for effective post-procedural care. Cardiac rehabilitation (CR) has emerged as a critical component of treatment in these patients. The most recent update of the European recommendations highlights the importance of including post-TAVI patients in CR programs. However, the benefits of CR in this particular patient group still need to be fully understood. The objective of this narrative review is to summarize the safety and benefits of post-TAVI CR by evaluating its impact on functional capacity, frailty, muscular strength, mental health, quality of life, and long-term survival. While emerging evidence supports its safety and effectiveness in the aforementioned outcomes, gaps remain regarding the optimal rehabilitation protocols, including the timing, duration, and intensity of CR as well as its long-term cardiovascular benefits. Further research is needed to develop personalized approaches for different patient groups. This article highlights the current knowledge, identifies critical gaps, and underlines the need for tailored rehabilitation strategies to improve post-TAVI recovery and patient outcomes. Full article
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