Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
4.1
2.4
Journals
Medicina
Special Issues
Valve Diseases: Diagnosis and Treatment Innovations
share announcement

Valve Diseases: Diagnosis and Treatment Innovations

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: closed (31 December 2025) | Viewed by 1189

Special Issue Editors

Dr. Vincenzo Caruso

E-Mail Website
Guest Editor
Cardiovascular Department, St. Thomas’ Hospital, London, UK
Interests: minimally invasive surgery; trans-catheter intervention; valve disease; stem cell
Dr. Rajdeep Bilkhu

E-Mail Website
Guest Editor
Cardiovascular Department, St. Thomas’ Hospital, London, UK
Interests: minimally invasive surgery; trans-catheter intervention; valve disease; operative outcomes

Special Issue Information

Dear Colleagues,

Cardiac surgery has recently seen significant advancements with innovative technologies reshaping cardiovascular care.

Valve diseases remain a major global health issue, necessitating novel approaches to improve patient outcomes.

This Special Issue presents cutting-edge research, comprehensive reviews, and expert opinions on the latest concepts revolutionizing cardiac surgery.

Focusing on minimally invasive techniques, robot-assisted surgeries, trans-catheter interventions, and hybrid procedures, this Special Issue highlights advancements that enhance recovery and reduce complications. Additionally, it explores regenerative medicine and tissue engineering, offering new therapeutic opportunities for patients with heart diseases. We will also address valve repair and the renewed interest in the Ross procedure, which is particularly important for infective endocarditis.

Also, with the idea of Heart Team, by fostering multidisciplinary collaboration among cardiac surgery, cardiology, and radiology experts, this Special Issue aims to inspire further research and innovation, ultimately striving to redefine the future of cardiac surgery and improve patient care.

Dr. Vincenzo Caruso
Dr. Rajdeep Bilkhu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • minimally invasive surgery
  • trans-catheter valve intervention
  • hybrid cardiac surgery
  • heart team
  • valve repair
  • Ross procedure
  • infective endocarditis

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

8 pages, 243 KB  
Article
Transthoracic Cross-Clamping Versus Endo-Aortic Balloon Occlusion in Minimally Invasive Mitral Valve Surgery: A Single-Center Retrospective Cohort Study
by Ahmed Shazly, Vincenzo Caruso, Arvind Singh, Alessia Rossi, Inderpaul Birdi and Antonio Bivona
Medicina 2026, 62(2), 370; https://doi.org/10.3390/medicina62020370 - 13 Feb 2026
Viewed by 542
Abstract
Background and Objectives: Minimally invasive surgery (MIS) has become a cornerstone approach in cardiac surgery. A debate persists regarding the optimal aortic clamp occlusion strategy, with limited comparative data. The two principal strategies, which are transthoracic cross-clamping (TTCC) and endo-aortic balloon occlusion (EABO), [...] Read more.
Background and Objectives: Minimally invasive surgery (MIS) has become a cornerstone approach in cardiac surgery. A debate persists regarding the optimal aortic clamp occlusion strategy, with limited comparative data. The two principal strategies, which are transthoracic cross-clamping (TTCC) and endo-aortic balloon occlusion (EABO), offer distinct advantages, but comparative clinical data remain limited. This study compares the two techniques in terms of procedural safety and early outcome. Materials and Methods: This single-center retrospective study included consecutive adult patients undergoing elective MIS via video-assisted right mini-thoracotomy between 2012 and 2018 for mitral valve surgery. Tricuspid repair, atrial fibrillation and redo surgery were included in the final cohort. Aortic occlusion was performed with transthoracic cross-clamping (TTCC) or endo-aortic balloon occlusion (EABO). Primary endpoints were intra-operative complications and the rate of conversion to full sternotomy; secondary outcomes were overall mortality and Society of Thoracic Surgeons (STS)-defined comorbidities. Results: A total of 163 patients were analyzed (TTCC: n = 99, 60%; EABO: n = 64, 40%). While both techniques demonstrated equivalent safety profiles (overall mortality: 0%), EABO was associated with higher conversion to full sternotomy [(n = 7, 10.9%) vs. TTCC (n = 1, 1.3%), p = 0.016]. In a generalized estimation equations (GEE) model, no patient-level covariate predicted conversion, suggesting technical or procedural factors as the primary contributors. In addition, EABO was associated with longer cross-clamp time [median: 87 min (IQR: 73, 100) vs. TTCC median: 77 min (IQR: 65.5, 87.5), p = 0.03]. Stroke, acute kidney injury, respiratory failure, reoperation and wound infection did not differ significantly; also, hospital stay was similar between groups. Conclusions: In this single-center series, EABO showed longer operative times and a higher conversion rate to sternotomy, but without excess mortality or major complications. This may be correlated with the initial learning phase and redo cases; further comparison is needed to assess the benefits of EABO. Full article
(This article belongs to the Special Issue Valve Diseases: Diagnosis and Treatment Innovations)
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-1
Back to TopTop