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Medicina
Special Issues
Recent Advances in Anesthesiology and Pain Medicine
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Recent Advances in Anesthesiology and Pain Medicine

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Intensive Care/ Anesthesiology".

Deadline for manuscript submissions: 31 January 2026 | Viewed by 8920

Special Issue Editors

Dr. Adam Rudnik

E-Mail Website
Guest Editor
Department of Neurosurgery, University Clinical Center, Faculty of Medical Sciences in Katowice, Medical University of Silesia, 40-055 Katowice, Poland
Interests: general anesthesia; neuroanesthesia; traumatic brain injury; perioperative care
Dr. Izabela Duda

E-Mail Website
Guest Editor Assistant
Department of Anesthesiology and Intensive Care, School of Medicine in Katowice, Medical University of Silesia, 40-572 Katowice, Poland
Interests: general anesthesia; neuroanesthesia; traumatic brain injury; perioperative care

Special Issue Information

Dear Colleagues,

Ensuring patient safety in the perioperative period is the most important task of modern anesthesiology. Anesthesiology as a clinical field is inextricably linked to technology. Technology has enabled the development of anesthesiology and made it safer. This relationship continues to increase patient safety even further. Clinical decision support and anesthesia information management systems are key areas of progress and controversy and have a significant impact on daily perioperative patient care.

There are many areas of anesthesiology in which dynamic development is observed. The most important include the use of minimally invasive techniques in monitoring vital functions. Other important issues include perioperative risk assessment, perioperative pain management, research on the mechanism of action of anesthetics, difficult airways, recognition of awareness and pain during operation, procedural sedation, and the organization of an integrated standard in anesthesiological care. However, many other areas of anesthesiological care also require discussion.

The main aim of this Special Issue of Medicina is to showcase new advances in anesthesiology and pain medicine. This Special Issue is open to studies covering new strategies and decision making.

We invite colleagues from around the world to report their experience and knowledge with original studies, case series or case reports, reviews, and meta-analyses.

Dr. Adam Rudnik
Guest Editor

Dr. Izabela Duda
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • anesthetic procedures
  • perioperative monitoring
  • airway management
  • pain management
  • standards of anesthesia
  • perioperative care

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (4 papers)

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Research

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12 pages, 490 KB  
Article
Prolonged Corrected QT Interval Is Associated with Lower Incidence of Maternal Hypotension During Spinal Anesthesia in Cesarean Delivery: A Prospective Observational Study
by Hee-Sun Park, Dong-Min Jang, Jong Yeon Park, Won Uk Koh and Woo-Jong Choi
Medicina 2025, 61(11), 1925; https://doi.org/10.3390/medicina61111925 - 27 Oct 2025
Viewed by 436
Abstract
Background and Objectives: Spinal anesthesia is a common anesthetic method for cesarean delivery. However, it is associated with spinal hypotension, which can negatively impact both the mother and the fetus. We hypothesized that parturients with preoperatively prolonged corrected QT interval (QTc) would [...] Read more.
Background and Objectives: Spinal anesthesia is a common anesthetic method for cesarean delivery. However, it is associated with spinal hypotension, which can negatively impact both the mother and the fetus. We hypothesized that parturients with preoperatively prolonged corrected QT interval (QTc) would have a lower incidence of developing spinal hypotension. Materials and Methods: This prospective observational study analyzed eighty-five parturients undergoing cesarean delivery. The participants were divided into two groups based on their baseline QTc, which was measured automatically using a patient monitor in the operating room rather than using a standardized 12-lead electrocardiogram: <440 ms (n = 42) or ≥440 ms (n = 43). Following combined spinal-epidural anesthesia, the incidence of spinal hypotension until delivery was analyzed and the vasopressor requirements within 30 min were compared between the QTc groups. The area under the receiver operating characteristic curve was measured to identify the optimal QTc cut-off for predicting spinal hypotension. Results: Spinal hypotension was observed in 37/43 parturients (86.0%) with QTc < 440 ms, compared to 17/42 (40.5%) with QTc ≥ 440 ms (p < 0.001). The total amount of phenylephrine significantly differed between groups (300 μg [100–400] vs. 100 μg [0–300], p = 0.009). The area under the ROC curve for spinal hypotension prediction was 0.75 (95% confidence interval [CI] 0.64–0.86). The optimal QTc cut-off interval, determined using the maximum Youden index (J = 0.510), which corresponded to the best combination of sensitivity and specificity, was 441 ms. Conclusions: These preliminary patient-monitor-based findings indicate an association between preoperative QTc and spinal hypotension, which should be validated using standardized electrocardiographic methods. Full article
(This article belongs to the Special Issue Recent Advances in Anesthesiology and Pain Medicine)
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Review

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13 pages, 597 KB  
Review
Current Perspectives on Remifentanil-PCA for Labor Analgesia: A Narrative Review
by Pia Vovk Racman, Miha Lučovnik and Tatjana Stopar Pintarič
Medicina 2025, 61(9), 1550; https://doi.org/10.3390/medicina61091550 - 29 Aug 2025
Viewed by 2942
Abstract
Remifentanil is a potent opioid characterized by a unique pharmacokinetic profile that makes it well-suited for analgesia in obstetrics. When administered in a patient-controlled analgesia (PCA) modality, remifentanil has become a recognized and versatile alternative for labor pain relief in cases where epidural [...] Read more.
Remifentanil is a potent opioid characterized by a unique pharmacokinetic profile that makes it well-suited for analgesia in obstetrics. When administered in a patient-controlled analgesia (PCA) modality, remifentanil has become a recognized and versatile alternative for labor pain relief in cases where epidural analgesia is contraindicated or is declined by the parturient. It offers mild to moderate pain relief, effectively decreasing pain from severe levels to a more manageable, moderate intensity. Remifentanil can be administered promptly and acts quickly, making it particularly useful in rapidly progressing or advanced labor. It can also benefit women with anxiety or tokophobia, as its sedative, anxiolytic, and euphoric effects help reduce pain perception and facilitate coping during labor. While it is not superior to epidural analgesia in terms of analgesic efficacy, remifentanil-PCA has obtained a role as a complementary pain-relieving option in several obstetric situations. Remifentanil-PCA is associated with high patient satisfaction, which is closely linked to realistic counseling and proper expectation management. The safety profile for both mother and neonate has been established; however, safety depends on cautious incremental dosing tailored to sedation levels, the use of supplemental oxygen, rigorous monitoring, and avoiding background infusion. Vigilant supervision by healthcare providers is essential, ideally supported by the continuous presence of an anesthesia team in the labor ward. Full article
(This article belongs to the Special Issue Recent Advances in Anesthesiology and Pain Medicine)
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17 pages, 1043 KB  
Review
Normal Haemostasis, Inherited Bleeding Disorders and Surgery: What Does the Anaesthesiologist Need to Know?
by Mihai Ștefan, Daniela Filipescu, Cornelia Predoi, Liana Văleanu, Ștefan Andrei and Dana Tomescu
Medicina 2025, 61(6), 1087; https://doi.org/10.3390/medicina61061087 - 13 Jun 2025
Viewed by 2932
Abstract
Haemostasis is a critical physiological process that ensures blood loss is minimised following vascular injury. Understanding the mechanisms of normal haemostasis is essential for managing patients with inherited bleeding disorders, particularly in the surgical setting. Inherited bleeding disorders, such as haemophilia and von [...] Read more.
Haemostasis is a critical physiological process that ensures blood loss is minimised following vascular injury. Understanding the mechanisms of normal haemostasis is essential for managing patients with inherited bleeding disorders, particularly in the surgical setting. Inherited bleeding disorders, such as haemophilia and von Willebrand disease (vWD), pose unique challenges for anaesthesiologists and surgeons due to the increased risk of excessive bleeding during and after surgery. This state-of-the-art review outlines the essential knowledge for anaesthesiologists regarding normal haemostasis, the pathophysiology of inherited bleeding disorders, and the perioperative management strategies required for these patients. It draws on existing literature and current clinical guidelines to offer practical approaches for assessing and managing bleeding risks in surgical settings. Full article
(This article belongs to the Special Issue Recent Advances in Anesthesiology and Pain Medicine)
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10 pages, 1376 KB  
Review
Rebound Pain After Regional Anaesthesia
by Frances Fallon, Mohd Shazrul Ramly and Aneurin Moorthy
Medicina 2025, 61(5), 790; https://doi.org/10.3390/medicina61050790 - 24 Apr 2025
Cited by 2 | Viewed by 1858
Abstract
The last decade of anaesthesia practice worldwide has seen considerable advancements in the field of regional anaesthesia with new equipment, techniques, and drug developments. With these advancements, regional anaesthesia practice has gained considerable momentum, and more patients benefit from it. Here, we review [...] Read more.
The last decade of anaesthesia practice worldwide has seen considerable advancements in the field of regional anaesthesia with new equipment, techniques, and drug developments. With these advancements, regional anaesthesia practice has gained considerable momentum, and more patients benefit from it. Here, we review rebound pain after regional anaesthesia, a common yet poorly understood phenomenon that all regional anaesthesiologists should be familiar with in order to recognise, manage, and, where possible, prevent it. Full article
(This article belongs to the Special Issue Recent Advances in Anesthesiology and Pain Medicine)
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