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Medicina
Special Issues
Updates on Oral Surgery
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Updates on Oral Surgery

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Dentistry and Oral Health".

Deadline for manuscript submissions: 20 November 2026 | Viewed by 5700

Special Issue Editors

Dr. Mario Caggiano

E-Mail Website
Guest Editor
Department of Medicine, Surgery and Dentistry, University of Salerno, 84084 Baronissi, Italy
Interests: implant dentistry; oral surgery; bone reconstructive surgery; dental materials; periodontology
Special Issues, Collections and Topics in MDPI journals
Dr. Alfonso Acerra

E-Mail Website
Guest Editor Assistant
Department of Medicine, Surgery and Dentistry, University of Salerno, 84084 Baronissi, Italy
Interests: oral surgery; implant dentistry; bone reconstructive surgery; dental materials; periodontology

Special Issue Information

Dear Colleagues,

Oral surgery is undergoing significant transformations due to the integration of new technologies, advanced surgical techniques and innovative biomaterials.

From minimally invasive procedures to digital planning and regenerative solutions, these advances are reshaping patient care, improving outcomes and expanding treatment options.

This Special Issue of Medicina, entitled "Updates on Oral Surgery", aims to highlight the latest developments in the field. These include novel surgical approaches, state-of-the-art imaging and navigation systems, 3D printing applications and biomaterials for improved tissue regeneration. This issue also encompasses technological innovations such as artificial intelligence in diagnostics and robotic surgery, which are laying the foundation for precision-guided interventions.

By bringing together research on these emerging trends, this Special Issue aims to provide a comprehensive resource for clinicians and researchers committed to the advancement of oral surgery. We invite contributions that address clinical applications, experimental studies and future directions in this dynamic and evolving specialty.

Dr. Mario Caggiano
Guest Editor

Dr. Alfonso Acerra
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • oral surgery
  • digital technology
  • minimally invasive techniques
  • biomaterials
  • regenerative medicine
  • 3D printing
  • artificial intelligence
  • surgical navigation
  • robotics

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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20 pages, 588 KB  
Article
Comparative Evaluation of Soft Tissue Regeneration Rate Using Different Wound Closure Methods After Palatal Donor Site Harvesting: A Retrospective Cohort Study
by Timofei Ryko, Anton Timoshin, Alla Shakaryants, Vitaly Borisov, Kirill Ershov, Maria Timoshina, Elena Emelina and Aglaya Kazumova
Medicina 2026, 62(5), 997; https://doi.org/10.3390/medicina62050997 - 20 May 2026
Viewed by 193
Abstract
Background and Objectives: This study evaluated the effect of two wound closure methods—polypropylene sutures and a butyl-2-cyanoacrylate tissue adhesive—on the rate of soft tissue regeneration following palatal donor site harvesting. A bovine collagen sponge, used as a secondary-intention dressing, was evaluated descriptively. [...] Read more.
Background and Objectives: This study evaluated the effect of two wound closure methods—polypropylene sutures and a butyl-2-cyanoacrylate tissue adhesive—on the rate of soft tissue regeneration following palatal donor site harvesting. A bovine collagen sponge, used as a secondary-intention dressing, was evaluated descriptively. Materials and Methods: Data from 300 patients (n = 100/group) with palatal donor sites were analyzed. Primary analysis compared suture vs. adhesive using Early Wound Healing Score (EHS) at days 7 and 14. Secondary outcomes were granulation tissue (day 7) and complications. Statistical methods: Mann–Whitney U test for between-group comparison (suture vs. adhesive); Kruskal–Wallis with Dunn’s post hoc for granulation across all three groups; Spearman’s correlation and logistic regression for the relationship between granulation tissue and EHS within primary healing groups. Results: At day 7, median EHS was similar between suture and adhesive groups (7.0 [interquartile range (IQR) 5.0–9.0] vs. 7.0 [IQR 7.0–9.0]; p = 0.31). By day 14, both groups achieved excellent healing (median 10.0, IQR 9.0–10.0 in both; p = 0.82). The collagen sponge group showed slower healing (median EHS day 7 = 4.0 [IQR 3.0–5.0], day 14 = 6.0 [IQR 5.0–7.0]), reported descriptively as expected for secondary intention. Granulation tissue on day 7 was highest in the adhesive group (p < 0.001 vs. collagen; p = 0.024 vs. suture). A strong positive correlation between day-7 granulation tissue and day-14 EHS was found in the primary-healing groups (ρ = 0.78, p < 0.001). Receiver operating characteristic (ROC) analysis established a granulation score ≥ 2 as the optimal cut-off for predicting successful healing (EHS ≥ 9) by day 14 (sensitivity 89.4%, specificity 76.0%, area under the curve (AUC) = 0.80), pending external validation. Conclusions: Surgical adhesive may be considered a viable alternative to sutures for palatal donor sites closed by primary intention, offering comparable healing by day 14. Collagen sponges result in slower healing and should be considered only when secondary intention is specifically desired. Early assessment of granulation tissue may serve as a simple prognostic indicator, but external validation is needed before clinical application. Full article
(This article belongs to the Special Issue Updates on Oral Surgery)
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16 pages, 329 KB  
Perspective
Impacted Mandibular Third Molar: Approaches and Current Perspectives in Surgical Therapy
by Federica Di Spirito, Pierpaolo Di Lorenzo, Iman Rizki, Alfonso Acerra, Francesco Giordano, Massimo Amato and Alessandro Santurro
Medicina 2025, 61(9), 1683; https://doi.org/10.3390/medicina61091683 - 17 Sep 2025
Cited by 5 | Viewed by 5062
Abstract
Mandibular third molar surgery is a procedure that can be accompanied by several complications, one of the most important being neurological ones, resulting from transient or permanent injury to the lingual nerve (LNI) or inferior alveolar nerve (IANI). For this reason, a conservative [...] Read more.
Mandibular third molar surgery is a procedure that can be accompanied by several complications, one of the most important being neurological ones, resulting from transient or permanent injury to the lingual nerve (LNI) or inferior alveolar nerve (IANI). For this reason, a conservative technique, coronectomy, has been proposed. Despite the fact that this procedure seems to have important advantages, such as IANI reduction, it turns out that it is currently a non-standardized procedure, showing several limitations and requiring a precise and well-documented informed consent process because its use may potentially increase the practitioner’s medico-legal vulnerability. Full article
(This article belongs to the Special Issue Updates on Oral Surgery)
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