Update on Surgical Treatment for Ovarian Cancer

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Obstetrics and Gynecology".

Deadline for manuscript submissions: 31 January 2026 | Viewed by 14

Special Issue Editors


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Guest Editor
Gynaecological Oncology Department, Metaxa Cancer Hospital, 18537 Piraeus, Greece
Interests: gynaecological oncology; robotic gynaecology; laparoscopic gynaecology; cancer; endometriosis
Special Issues, Collections and Topics in MDPI journals

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Guest Editor Assistant
Department of Gynecologic Oncology, Metaxa Memorial Cancer Hospital, 51 Botassi Str., 18537 Piraeus, Greece
Interests: gynaecologic oncology; ovarian cancer

Special Issue Information

Dear Colleagues,

The first recorded surgical removal of an ovarian tumour was performed in 1809 in a patient with a large abdominal mass by Dr. Ephraim McDowell. Remarkably, the patient made a full recovery and lived another 32 years. This groundbreaking procedure is considered the first successful ovariotomy, marking a major milestone in the surgical treatment of ovarian cancer.

Today, surgical resection remains the cornerstone of multidisciplinary treatment for patients with resectable ovarian cancer. Recent advances have significantly transformed this field. These include hyperthermic intraperitoneal chemotherapy (HIPEC), minimally invasive surgery (MIS), fertility-preserving procedures, real-time intraoperative tools, AI-assisted technologies, and machine learning, neoadjuvant chemotherapy (NACT) to reduce the tumour burden preoperatively. There is a growing emphasis on combining these technologies to enhance surgical precision, broaden patient eligibility, improve quality of life, and predict disease recurrence more accurately, with the ultimate goal of achieving long-term survival.

This Special Issue will highlight recent innovations that could reshape current clinical practice and inform future clinical trials, while also introducing multiple new perspectives in relation to ovarian cancer surgery, such as patient-specific 3D modelling and simulation and immunological/neurobiological integration as a polyvagal perspective in stress, recovery, and resilience in ovarian cancer surgery.

Dr. Christos R. Iavazzo
Guest Editor

Dr. Victoria Psomiadou
Guest Editor Assistant

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Keywords

  • ovarian cancer
  • surgical resection
  • ovariotomy
  • HIPEC (hyperthermic intraperitoneal chemotherapy)
  • minimally invasive surgery (MIS)
  • neoadjuvant chemotherapy (NACT)
  • fertility-preserving procedures
  • AI-assisted technologies

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