Prophylaxis, Diagnosis, and Treatment Strategies of Gastric Cancer
A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Oncology".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 1184
Special Issue Editors
Interests: surgery
Special Issue Information
Dear Colleagues,
Gastric cancer (GC) is a malignancy that is both aggressive and diverse. It is one of the most prevalent cancers in the world and a significant global health concern owing to the fact that it has a high death rate and poor prognosis.
There are two types of early screening for stomach cancer: mass screening, which is used on large populations, and opportunistic screening, which is used on people who are at risk.
Endoscopy and imaging are diagnostic methods that are utilized for the qualitative localization and staging of gastric cancer. These tools are considered to be the fundamental diagnostic tools for gastric cancer. Physical examination, laboratory testing, biopsy of metastases, diagnostic laparoscopic exploration, and study of abdominal lavage fluid are some of the other procedures that may be performed. The most fundamental method for pre-treatment staging is contrast-enhanced computer tomography (CT) of the thorax, abdomen, and pelvis. In addition, magnetic resonance imaging (MRI), laparoscopic exploration, and positron emission tomography (PET) are used as alternate methods for CT suspicion of liver metastases, peritoneal metastases, and lung metastases, respectively.
In the case of stomach cancer, the clinical stage should be taken into consideration while selecting the most suitable treatment strategy. Treatment using endoscopic techniques, including endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD), is the method of choice for patients with in situ stomach. Open or laparoscopic surgery should be conducted on individuals who have localized cancer with curative intention. Patients with loco-regionally and systemically advanced gastric cancer who cannot undergo surgical options present a significant challenge in terms of treatment. It is now widely acknowledged that a combination of systemic drug chemo- or immunotherapy and local therapies, including palliative surgery, radiotherapy, and peritoneal perfusion, can be utilized in order to effectively treat these patients.
Improved early cancer detection, more appropriate monitoring of gastric premalignant lesions, more precise identification of patients who are likely to benefit from specific treatments, and a better understanding of gastric carcinogenesis in order to develop new therapeutic targets are all areas that need to be addressed in the field of gastric cancer.
We are looking forward to receiving articles on subjects related to the diagnosis, treatment, and prevention of stomach cancer for this Special Issue.
Dr. Andra Ciocan
Prof. Dr. Nadim Al Hajjar
Guest Editors
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Keywords
- gastric cancer
- treatment
- prevention
- diagnosis
- surveillance
- follow-up
- neoadjuvant therapy
- prognosis
- biomarkers
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