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Life
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Laparoscopy and Treatment: An All-Encompassing Solution for Surgeons
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Laparoscopy and Treatment: An All-Encompassing Solution for Surgeons

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".

Deadline for manuscript submissions: closed (26 October 2025) | Viewed by 2218

Special Issue Editors

Prof. Dr. Niculae Iordache

E-Mail Website
Guest Editor
1. Department of Surgery, “Carol Davila” University of Medicine and Pharmacy, 37, Dionisie Lupu Street, 020021 Bucharest, Romania
2. General Surgery Department, “Sf. Ioan” Clinical Emergency Hospital, 13 Vitan-Bârzeşti Road, 042122 Bucharest, Romania
Interests: oncological; staging laparoscopy; tool; radical surgery; diagnostic
Dr. Claudiu-Octavian Ungureanu

E-Mail Website
Guest Editor
1. Department of Surgery, “Carol Davila” University of Medicine and Pharmacy, 37, Dionisie Lupu Street, 020021 Bucharest, Romania 2. General Surgery Department, “Sf. Ioan” Clinical Emergency Hospital, 13 Vitan-Bârzeşti Road, 042122 Bu-charest, Romania
Interests: Laparoscopic surgery, colorectal surgery, coloproctology, hernia surgery, incisional hernia surgery
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In an era where patient-reported outcomes have become more important, one of the tools that every surgeon should have in their bag is diagnostic laparoscopy. This versatile instrument can serve as a diagnostic confirmation and definitive treatment. Through a couple of trocars placed into the abdomen, a surgeon can diagnose a variety of surgical ailments, such as bowel infarction, the site of obstruction in bowel obstruction, occult hernias, and, last but not least, trauma. In addition, the oncological field is another place where it shines: intraperitoneal tumors, peritoneal carcinomatosis, and superficial liver metastases that were not identified upon imaging. Staging laparoscopy is recommended for pancreatic and gastric cancers, thus providing a potential indication for radical surgery. Laparoscopy is not only diagnostic, but after identifying the nature of the surgical disease one can perform various laparoscopic surgeries with net advantages when compared to the open approach.

Prof. Dr. Niculae Iordache
Dr. Claudiu-Octavian Ungureanu
Guest Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • oncological
  • staging laparoscopy
  • tool
  • radical surgery
  • diagnostic

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Published Papers (3 papers)

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Research

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10 pages, 358 KB  
Article
Male Gender Is a Contributing Risk Factor to Predict Sticky Fat in Laparoscopic Partial Nephrectomy
by Erkan Olcucuoglu, Samet Senel, Muhammed Emin Polat, Kazim Ceviz, Emre Uzun, Mevlut Berk Ceri, Antonios Koudonas, Caglar Sarioglu, Yusuf Kasap, Esin Olcucuoglu and Sedat Tastemur
Life 2025, 15(12), 1913; https://doi.org/10.3390/life15121913 - 14 Dec 2025
Viewed by 120
Abstract
Objective: This study aimed to identify predictive factors for adherent perinephric fat (APF), or sticky fat, in patients undergoing laparoscopic partial nephrectomy (LPN), with particular emphasis on evaluating male gender as an independent risk factor beyond the Mayo Adhesive Probability (MAP) Score. Materials [...] Read more.
Objective: This study aimed to identify predictive factors for adherent perinephric fat (APF), or sticky fat, in patients undergoing laparoscopic partial nephrectomy (LPN), with particular emphasis on evaluating male gender as an independent risk factor beyond the Mayo Adhesive Probability (MAP) Score. Materials and Methods: A retrospective analysis was performed on 197 patients who underwent LPN for localized renal tumors between December 2019 and September 2025. Demographic, clinical, radiological, intraoperative, and postoperative variables were collected. Sticky fat was defined intraoperatively. MAP scores were calculated using posterior perinephric fat thickness and fat stranding. Statistical analyses included Mann–Whitney U and Chi-square tests, as well as univariate and multivariate logistic regression (Backward LR method). ROC analysis was used to determine predictive performance. Results: The mean age was 61.3 ± 13.1 years, and 63.5% of patients were male. Sticky fat was observed in 41.6% of cases. Male gender (71.3% vs. 52.4%, p = 0.007), older age (62.9 vs. 58 years, p = 0.031), and higher MAP scores (p = 0.005) were significantly associated with sticky fat. Multivariate analysis identified male gender (OR = 1.97; 95% CI: 1.07–3.61; p = 0.029) and MAP score (OR = 1.27; 95% CI: 1.04–1.56; p = 0.021) as independent predictors. Combining MAP score and gender improved predictive accuracy (AUC = 0.645). Conclusions: Male gender independently predicts APF, and combining gender with MAP score enhances preoperative assessment and surgical planning. Full article
(This article belongs to the Special Issue Laparoscopy and Treatment: An All-Encompassing Solution for Surgeons)
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11 pages, 5203 KB  
Article
Laparoscopic and Robot-Assisted Laparoscopic Management of Iatrogenic Ureteral Strictures: Preliminary Experience
by Roxana Andra Coman and Bogdan Petrut
Life 2025, 15(4), 645; https://doi.org/10.3390/life15040645 - 14 Apr 2025
Viewed by 1349
Abstract
Iatrogenic ureteral strictures are uncommon but challenging to manage. We present our expertise in laparoscopic and robot-assisted laparoscopic ureteroureterostomy (LUU and RAUU) for lumbar and iliac strictures and laparoscopic ureteral reimplantation for pelvic strictures. A descriptive study was conducted on nine adult patients [...] Read more.
Iatrogenic ureteral strictures are uncommon but challenging to manage. We present our expertise in laparoscopic and robot-assisted laparoscopic ureteroureterostomy (LUU and RAUU) for lumbar and iliac strictures and laparoscopic ureteral reimplantation for pelvic strictures. A descriptive study was conducted on nine adult patients who underwent minimally invasive procedures. Six had lumbar or iliac ureteral strictures—five due to ureterorenoscopy and one following pancreaticoduodenectomy for pancreatic cancer. Three developed pelvic strictures after ureterorenoscopy. Preoperative evaluation included a medical history review, abdominal ultrasound, and CT scan. Success was characterized by the absence of symptoms and the lack of obstruction on follow-up imaging at one year. All procedures were technically feasible, with a median operating time of 105 min and a median hospital stay of four days. No major complications occurred. One patient experienced ureteral stricture recurrence following a laparoscopic approach for a lumbar stricture, and required a permanent double-J stent. At a median follow-up of 38 months, 88.88% of patients remained asymptomatic with preserved renal function. Our findings suggest that robotic and laparoscopic ureteral reconstruction performed by experienced surgeons at a tertiary center is a safe and effective option with a low complication rate. Full article
(This article belongs to the Special Issue Laparoscopy and Treatment: An All-Encompassing Solution for Surgeons)
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Review

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12 pages, 1657 KB  
Review
Laparoscopic Management of Boerhaave Syndrome: Case Series and Narrative Review
by Floris Cristian Stănculea, Andrei Razvan Stoica, Claudiu Octavian Ungureanu, Raul Mihailov, Octav Ginghina, Mircea Litescu, Niculae Iordache, Nicoleta Alina Mares and Alexandru Iordache
Life 2025, 15(12), 1865; https://doi.org/10.3390/life15121865 - 5 Dec 2025
Viewed by 180
Abstract
Boerhaave syndrome, or spontaneous rupture of the esophageal wall, is a rare condition that occurs after a violent increase in intraesophageal pressure associated with negative intrathoracic pressure after forceful vomiting or retching. Rupture, usually transmural, often occurs in the distal esophagus and can [...] Read more.
Boerhaave syndrome, or spontaneous rupture of the esophageal wall, is a rare condition that occurs after a violent increase in intraesophageal pressure associated with negative intrathoracic pressure after forceful vomiting or retching. Rupture, usually transmural, often occurs in the distal esophagus and can be complicated by mediastinitis, sepsis, and multiple organ dysfunction. Despite the aid of imaging in diagnosis and rapid management, it is still characterized by a high mortality rate. Surgical and endoscopic approaches are the mainstays of treatment. Case presentation: Here, we describe three cases of Boerhaave’s syndrome managed with minimally invasive surgical treatment and provide a brief literature review of the treatment methods for this rare condition. Conclusions: Early diagnosis and prompt management by a multidisciplinary team increase the chances of survival. The laparoscopic approach is beneficial and can successfully treat esophageal tears associated with this syndrome in early or delayed timing. Full article
(This article belongs to the Special Issue Laparoscopy and Treatment: An All-Encompassing Solution for Surgeons)
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