Life, Volume 15, Issue 9

Introduction: Penile fibro-ligaments have been extensively studied for many centuries; however, there is, unfortunately, a lack of thorough understanding. We aimed to bridge the research gap between anatomy and surgical reconstruction. Methods: We ex...

In response to the growing demand for agricultural production and the need for more sustainable practices, the use of biofertilizers based on the valorization of agricultural residues is presented as an alternative to traditional chemical fertilizers...

This study evaluated six supervised machine learning (ML) models for early detection of subclinical ketosis and low-grade ruminal acidosis in dairy cows during the transition period. Ninety-four Holstein cows were monitored for 21 days postpartum usi...

Rootstock choice offers a powerful lever for tailoring economically important trees to adverse environments. Camellia oleifera Abel., a premier oil-producing species cultivated widely on red-soil hills, suffers large yield losses under chronic phosph...

Background: Sepsis is a leading cause of morbidity and mortality among patients receiving maintenance hemodialysis (HD), reflecting a unique combination of immunologic dysfunction, comorbidities, and healthcare-related exposures. Despite advances in...

In recent years, in response to the demand for the livestock industry to enhance cattle production performance, scholarly inquiries have centered on elucidating the underlying mechanisms by which feed additives modulate rumen microenvironment and met...

Background: Deep gluteal syndrome (DGS) is an underdiagnosed cause of sciatica-like pain, involving the entrapment of the sciatic nerve by various structures within the subgluteal space. While cases of ossification or calcification in the context of...

Drought stress critically constrains agricultural productivity in arid and semi-arid regions, necessitating the development of drought-tolerant crop varieties for sustainable food security. This study evaluated drought tolerance in 222 foxtail millet...

Background: The application of sunscreen after light and laser facial treatments is vital for optimizing patient outcomes and minimizing complications. This review aims to highlight the importance of sunscreen use in post-procedural care within aesth...

Background: In arterial hypertension (AH), adverse hemodynamic consequences in the left atrium (LA) are often observed. The prognostic significance of functional vs. structural LA abnormalities among high-risk AH patients (with heart failure with pre...

Anomalous origin of the Left Coronary Artery from the Pulmonary Artery (ALCAPA), also known as Bland-White-Garland syndrome, is a rare congenital coronary anomaly with an estimated incidence of 1 in 300,000 live births. While commonly diagnosed in in...

Background: Despite anatomically successful surgical correction, postoperative hypertension remains a significant concern in patients with coarctation of the aorta, even when repair is performed during infancy. Inflammation and neurohormonal activati...

Background/Objective: Parkinson’s disease (PD) is the most common neurodegenerative movement disorder, in which the inflammatory hypothesis posits that dysregulation of the immune system is an important factor in its etiology. Based on our prev...

Sepsis causes profound microcirculatory dysfunction, where heterogeneous capillary perfusion and abnormal vasomotion contribute to tissue hypoxia and organ failure. Sublingual videomicroscopy is established in large animals and humans to monitor thes...

The process of dissection is essential to the study of anatomy, with the variety of colours, shapes, patterns and textures revealing the distinctive features of each anatomical system, but it can also be misleading, because while the body’s con...

Metal oxide nanoparticles, such as ZnONPs and TiO₂NPs, are increasingly applied in various industries. However, their effects on photosynthetic microorganisms at environmentally relevant concentrations remain poorly understood. This study evaluated t...

Background: The ice plant (Mesembryanthemum crystallinum L.) is a typical halophyte with remarkable stress resistance traits, including salinity and alkalinity tolerance. As a crucial signaling transduction pathway for plant responses to environmenta...

In the present study, a new Ganoderma sp. (ZHM1939) was collected from Lincang, Yunnan, China, and described on the basis of morphological characters and multigene phylogenetic analysis of rDNA-ITS, TEF1α and RPB2 sequences. This fungus is char...

Background/Objectives: Gastric mucosal lesions represent a significant health burden, with Helicobacter pylori infection being the primary cause of chronic gastritis worldwide. However, the role of modifiable lifestyle factors in modulating the sever...

Diabetic retinopathy (DR) causes visual impairment and blindness in millions of diabetic patients globally. Fundus image-based Automatic Diabetic Retinopathy Classifiers (ADRCs) can ensure regular retina checkups for many diabetic patients and reduce...

This study investigates the taxon composition, seasonal variations, and diversity dynamics of macroinvertebrate communities associated with Mytilus galloprovincialis cultivated in mussel longline systems in the central Black Sea. Monthly sampling con...

It is estimated that one in four people worldwide carries Mycobacterium tuberculosis bacteria. MPT64 is a protein exclusively secreted by Mycobacterium tuberculosis complex (MTC) bacteria. It serves as a crucial diagnostic marker and plays a role in...

Traumatic brain injury (TBI) is a major global health concern and a leading cause of long-term disability and mortality. While the primary mechanical insult is often the focus of acute care, secondary injury mechanisms—particularly cerebrovascu...

Objective: This cross-sectional study aimed to investigate the associations between physical performance, gait variability, and fall risk in community-dwelling older adults. Methods: A total of 446 participants were divided into fall-risk and non-fal...

Cadmium exposure has been associated with shortened telomeres, alterations in DNA methylation patterns, and increased mortality. However, the role of DNA methylation in mediating the relationship between cadmium and telomere dynamics is still unclear...

Introduction: Expanded hemodialysis using medium cut-off (MCO) dialyzers effectively removes middle-molecule uremic toxins, comparable to hemodiafiltration, but their single-use designation increases the dialysis costs. This study evaluated the effic...

5-aminolevulinic acid (5-ALA) is a heme precursor involved in mitochondrial activation. A clinical study suggested that 5-ALA supplementation alleviates fatigue in healthy individuals who experience chronic physical tiredness. However, the detailed m...

Glechoma hederacea L. (GH) is an understudied species with significant phytotherapeutic potential, whose botanical characteristics and phytochemical profile have not previously been investigated from Bihor County, North-West Romania, namely Săld...

Background: Sarcoidosis is a systemic inflammatory disease characterized by the formation of non-caseating granulomas, predominantly affecting the lungs and lymph nodes. However, the disease can affect any organ, including the eye, where it most comm...

Objective: We aimed to determine the incidence and screening outcomes of retinopathy of prematurity (ROP) in preterm infants managed at a tertiary neonatal intensive care unit (NICU) and to identify associated risk factors. Material and Methods: Medi...

Acute rejection and infections are the most frequent complications in the first year after lung transplantation, often representing relevant causes of death. There is still no consensus on the ideal strategy for preventing these events, with a still...

Neuronal chloride (Cl⁻) homeostasis is fundamental for brain function, with disruptions increasingly recognized as pathogenic across neurological disorders. This review synthesizes evidence from preclinical models and clinical studies, integrat...

Objective: The role of calcium in coagulation homeostasis is well established, although the relationship between calcium levels and postoperative bleeding in major cardiac surgery remains largely unexplored. Methods: This retrospective, single-center...

The main goal of this study was to consider the role of obesity/overweight as a potential modifier of associations between gene single nucleotide polymorphisms (SNPs) affecting the sex hormone-binding globulin level (SHBG_level) and uterine myoma (UM)...

Fibromyalgia (FM) is characterized by widespread musculoskeletal pain and tenderness, cognitive dysfunction, fatigue, and insomnia. Electroacupuncture (EA) has documented efficacy against FM-associated pain, while cannabinoid receptor 1 (CB1) plays a...

Refractory neuropathic pain of the head and neck remains a major clinical challenge, particularly when mediated through the cervicotrigeminal complex (CTC), a unique anatomical hub integrating trigeminal and upper cervical nociceptive inputs. This na...

Annexin A3 (ANXA3) is a calcium-binding protein that plays a role in membrane phospholipid metabolism and inflammation, and significant alterations have been shown in some psychotic disorders. Because its association with major depressive disorder (M...

This study evaluated the utility of the 2HELPS2B score in predicting seizures from routine electroencephalographs (rEEGs). In total, 670 rEEGs obtained in a medical intensive care unit (MICU) between October 2018 and March 2023 were analyzed. More th...

Background: Premenstrual syndrome (PMS) affects 950 million women worldwide. However, conventional pharmacological treatments offer limited improvements. Objective: This study aimed to evaluate the effectiveness of the FemmeBalance supplement in reli...

Background: Purpureocillium lilacinum (P. lilacinum) is an emerging filamentous fungus known to cause opportunistic infections, particularly in immunocompromised patients. Formerly known as Paecilomyces lilacinus, this pathogen is widespread in the e...

Background: One of the important mechanisms of depression is long-term high levels of inflammation. Exercise may help relieve depressive symptoms and is associated with anti-inflammatory effects. This research methodically assesses how various exerci...

The present work focuses on seven megaliths sampled for the first time as a continuation of our studies on the biodiversity of algae on megaliths in Bulgaria. A total of 55 species from four divisions were identified (Chlorophyta was the richest with...

Cardiovascular diseases (CVDs) are generally associated with adulthood, although the underlying processes may begin in childhood and adolescence. Thus, detecting increased cardiovascular risk in adolescence is essential for prevention. In this cross-...

Microplastics (MPs) and nanoplastics (NPs) have emerged as ubiquitous environmental contaminants that pose significant threats to human health, with multiple exposure pathways (e.g., ingestion and inhalation) contributing to systemic exposure. Althou...

Ochradenus baccatus (O. baccatus), a resilient medicinal plant native to arid regions, was systematically investigated for its neuroprotective potential against Alzheimer’s disease. Comprehensive phytochemical profiling of different plant parts...

Skin cancer is the most common cancer worldwide. The incidence of skin cancer has been increasing worldwide. Nearly 75% of all skin cancers are basal cell carcinomas (BCC), cutaneous squamous cell carcinoma (cSCC) represents approximately 20%, and th...

The ancestry of domestic species from their closest wild relatives is one of the most debated and intriguing topics in evolutionary genetics. This review synthesizes current scientific understanding of the phylogenetic relationships between wild mouf...

Diagnosis of neuropsychiatric (NP) involvement in pediatric systemic lupus erythematosus (pNPSLE) remains challenging due to NP symptom heterogeneity, lack of specific clinical criteria and validated diagnostic biomarkers, and invasiveness of common...

Certain esophageal diseases have a predilection for affecting different parts of the esophagus. This predilection is noted in our clinical practice as we investigate various esophageal diseases using multiple imaging and motility studies, as well as...

In metabolic syndrome, cardiomyocyte changes induced by metabolic and proinflammatory factors impair repolarization and exacerbate the heterogeneity of the transmural dispersion of repolarization, and this is proarrhythmogenic. Limited data in the li...